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Effects of Food Material Water Extracts on Content of Testosterone and Dihydrotestosteron in Serum and Skin of Rat  

이윤경 (대구가톨릭대학교 식품산업과학연구소)
김정기 (대구가톨릭대학교 식품산업과학연구소)
조종원 (바오로식품)
김순동 (대구가톨릭대학교 식품산업학부)
Publication Information
Food Science and Preservation / v.10, no.1, 2003 , pp. 94-98 More about this Journal
Abstract
Effect of mixture of food material water extracts(modouri) composed of Job's tears, maize, buckwheat Japanese mushroom, lovage, licorice and jujube(13 : 50 : 15 : 2 : 5 : 5 : 5, v/v)] on the content of testosterone(T) and dihydrotestosterone(DHT), biochemical and histological changes of rat were investigated. Animal experiments(30 rats) were divided into 3 experimental groups(control, modouri and propecia). The summarized results were as follows: Activities of GOT, GPT, ALP, ${\gamma}$-GTP and content of total cholesterol and total lipid are normal in modouri group. Therefore modouri does not give rise to any damage in the liver. Also in the histological view, modouri does not have any hepatotoxic effect and increase the number of hair folicle. Total(T+DHT) and DHT content in rat serum and skin are significantly decrease in modouri group compare to the control but there is not any significant difference with propecia.
Keywords
food material water extracts; testosterone; dihydrotestosterone; cholesterol;
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