• Title/Summary/Keyword: Lots Conditions

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Development of Dissolution Test Method for Acebrophylline Capsules and Bromhexine Hydrochloride Tablets in Korean Pharmaceutical Codex (고시수재 의약품 중 아세브로필린 캡슐 및 브롬헥신염산염 정의 용출시험법 개발)

  • Lee, Tae-Woong;Jeong, Rae-Seok;Jeong, Seung-A;Kim, Jeong-Hyun;Shim, Young-Hun;Kim, In-Kyu;Park, Chang-Won
    • YAKHAK HOEJI
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    • v.57 no.3
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    • pp.226-233
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    • 2013
  • Although the dissolution test can serve as an effective tool for quality control and predictor of in vivo performance, there are a number of drugs with no established dissolution specification in Korean Pharmaceutical Codex (KPC). So, with each reference and test drugs, the dissolution test method and an analytical procedure by HPLC were developed and validated to establish dissolution specification for acebrophylline capsules and bromhexine hydrochloride tablets. The dissolution condition was determined based on the "Guidelines on Specifications of Dissolution tests for Oral dosage forms" of Ministry of Food and Drug Safety (MFDS). The analytical method of HPLC was validated in specificity, linearity, precision and accuracy. Final dissolution test was performed with commercially available samples of 3 lots to establish specification. In addition, no difference was observed by the inter-laboratory evaluation. Dissolution specifications and conditions will be used for revising the monograph of acebrophylline capsules and bromhexine hydrochloride tablets in next supplement of KPC.

The Influence Analysis for Soil Loss in Reservoir Slant using GIS-based Soil Loss Model (GIS기반 토사유실모델을 이용한 저수지 사면의 토사유실 영향 분석)

  • Lee, Geun-Sang;Park, Jin-Hyeog;Hwang, Eui-Ho;Koh, Deuk-Koo
    • Journal of the Korean Association of Geographic Information Studies
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    • v.7 no.3
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    • pp.108-117
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    • 2004
  • Soil particles from rainfall flow into reservoir and give lots of influence in water quality because the geological conditions and landcover characteristics of Imdong watershed have a weakness against soil loss. Especially, reservoir slant is indicated by the main source area of soil loss. This study selected RUSLE model that could apply GIS and satellite image to evaluate the contribution rate of soil loss in reservoir slant. And we carried out an on-the-spot survey for the range, width and condition of reservoir slant that give much influences to the accuracy of soil loss. As the result of evaluation to the influence of soil loss in reservoir slant, it showed 2.64% in comparison with Imdong watershed. In view of these results, the influence of soil loss in reservoir slant was evaluated in low comparing with Imdong watershed relatively.

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Case Study of Characteristic of Ground Deformation and Strut Axial Force Change in Long Span Deep Excavation(II) (장지간 깊은 굴착에서 지반변형 및 버팀보 축력변화 특성 사례연구(II))

  • Kim, Sung-Wook;Han, Byung-Won
    • Proceedings of the Korean Geotechical Society Conference
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    • 2010.03a
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    • pp.248-259
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    • 2010
  • In the case of relatively good ground and construction condition in the deep excavation for the construction of subway, railway, building etc., flexible earth retaining systems are often used in an economical point of view. It is generally known that the mechanism of behavior in the flexible earth retaining system is relatively more complicated than the rigid earth retaining system. Moreover in the case of long span strut supporting system the analysis of strut axial force change becomes more difficult when the differences of ground condition and excavation work progress on both sides of excavation section are added. When deeper excavation than the specification or installation delay of supporting system is done or change of ground condition is faced due to the construction conditions during construction process, lots of axial force can be induced in some struts and that can threaten the safety of construction. This paper introduces one example of long span deep excavation where struts and rock bolts were used as a supporting system with flexible wall structure. The characteristics of ground deformation and strut axial force change, the measured data obtained during construction process, were analysed, the effects of relatively deeper excavation than the specification on one excavation side and rapid drawdown of ground water level on the other excavation side were deeply investigated from the viewpoint of mutual influences between ground deformations of both excavation sides and strut axial force changes. The effort of this article aims to improve and develop the technique of design and construction in the coming projects having similar ground condition and supporting method.

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Remodeling Strategies for Governance of Trade in Services in Korea (서비스무역 거버넌스 분석과 리모델링 전략)

  • Park, Moon-Suh
    • International Commerce and Information Review
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    • v.11 no.2
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    • pp.173-201
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    • 2009
  • As a result of overemphasizing the goods sector in trade structure, Korea does not meet properly the global trend which has the key role of 'trade in services' as the service economy have been expanded. Hereafter, it is easily forecasted that trade in services will be one of the main factors for Korea's competitiveness and engine of growth. Nevertheless, because Korea does not equip the concreteness of governance for trade in services, it is possible that the efficiency deterioration of trade volume, confusion of Korea's trade policy, conflict among trading countries, and discordance between the interested parties may be occurred. This paper analyzes the governance system of Korea for trade in services in order to enhance the competitiveness reflecting the importance of trade in services and to draw some strategies for remodeling the service governance system. It is expected to raise the efficiency of Korea's trade policy by constructing the systematic governance for trade in services, and to remove lots of latent risks during global transactions by improving the imbalance between manufacturing and service part for the development of trade in services in Korea. Analysis revealed itself the result that Korea is weak enough to can not identify the governance system about trade in services. Except 'Extent of Services' article of the Foreign Trade Act, Korea has not prepared the governance system for trade in services so that governance system have been scattered overly or decentralized. Problems about trade in services are not limited to enterprise's side, but extended to all the players including government agency whole, academic world and research institute. Therefore, the governance of trade in services should be strengthened and systematized by making the model law for trade in services(provisional name : Master Law for Trade in Services or Promotion Law for Trade in Services) by formatting type of fundamental law or separate legislation. If the bill legislation does not meet the conditions, the Foreign Trade Act should be totally reformed to Omnibus Trade Act concept including trade in services.

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House Type and Household Structures of South Kyongsang Province in the Enlightenment Period (『가호안』 분석을 통해 본 개화기 경상남도의 가옥형태와 구조)

  • 최영준
    • Journal of the Korean Geographical Society
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    • v.39 no.3
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    • pp.297-320
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    • 2004
  • Household Register of South Kyongsang Province compiled by the Korean government in 1904 keeps complete details on local houses of eleven out of a total of thirty-one counties in the district. This study examines, band on e analysis of the primary source materials, e specifics of traditional housing of South Kyongsang Province with special reference to the magnitude of housing lots, size of dwellings, land and house ownership, and distribution of thatch and tile roof houses by dong, myon and county. Findings from the survey of the household register suggest that approximately 20 percent of households were established on the private or rented public lands, that 90 percent resided in undersized housing with just one or two rooms besides a kitchen, and that the regional average of dwelling size was no bigger than 2.75 rooms. The fact clarifies that the three-room thatch houses prevailed in South Kyongsang Province about a century ago. The miserable living conditions were tranalated into a constricted personal space of 2 to 4 square meters and a small-size household of less than 4 family members.

Experiment for the Performance Improvement of Eco House Provided by Habitat for Humanity Nepal(HfH_Nepal) - Case Study of Terai Plain Region, Nepal - (네팔 해비타트(HfH_Nepal) 생태주택 보급현황과 성능개선실험 연구 - 떠라이 평원지역을 중심으로 -)

  • Leem, Youn Taik
    • KIEAE Journal
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    • v.13 no.4
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    • pp.103-112
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    • 2013
  • The Federal Democratic Republic of Nepal(Nepal) is one of the poorest country in the world. People in Nepal are having lots of housing problems including the lack of housing provision. Even Habitat for Humanity Nepal (HfH_Nepal) has developed various programs to diffuse ecological housing, still there are many problems due to financial and technological shortage. The purpose of this study is to verify the effects of suggestion of performance improvement for HfH_Nepal eco house with introduction of the housing situation and efforts to provide sustainable housing by HfH_Nepal in Terai plain. Ideas on CGI sheet roof with poor insulation, double panel bamboo wall and adobe brick wall which can overcome structural and waterproof flaws of the thin single panel bamboo wall. The experiment result shows that both ideas adapted to adobe brick house reduces daily temperature range 50.8% and humidity adjust effect. For the effective provision of adobe brick house, compressive strength was tested for the bricks made with locally available fiber materials. Brick with jute displayed 41.1% betterment than plain brick with closest packing condition while coconut and straw showed 25.1% and 7.9% improvement respectively. Technical and economic problems brought up during the building and experiment process were listed and countermeasures established. This kinds of building prototype houses and experiments can improve the living conditions of people in developing countries with little supplement of resources. Furthermore, consideration of locally available and affordable material can help the social and ecological sustainability in the world.

Study on Inverse Modeling of a Turboprop in High Altitude Operation using Engine Performance Data (성능데이터를 이용한 고고도운용 터보프롭엔진 역모델링 연구)

  • Kong, Chang-Duk;Lim, Se-Myeong;Kim, Ji-Hyun
    • Journal of the Korean Society of Propulsion Engineers
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    • v.14 no.3
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    • pp.16-22
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    • 2010
  • The gas turbine engine performance relies greatly on its component performance characteristics. Generally, engine manufacturers do not provide engine purchasers the component performance characteristics which can be obtained by lots of experimental tests at various operating conditions and big amount of expenses. In previous works the component maps have mostly been generated by scaling from a similar component map. However this scaling method has large error at off design points, specially in high altitude operation. Therefore this work proposes an inverse modeling method that can generate components maps of PT6A-67A turboprop engine using performance data provided by the engine manufacturer. In addition, evaluation can be made through comparison between performance analysis results using the performance simulation program including the generated compressor map and performance data.

Analysis of Aerodynamic Characteristics for determination of tunnel cross section in Honam high speed railway (호남고속철도 터널 단면선정을 위한 공기역학적 특성 분석)

  • Kim, Seon-Hong;Moon, Yeon-Oh;Seok, Jin-Ho;Jo, Hyeong-Jae;Yoo, Ho-Sik;Choi, Jeong-Hwan;Rim, Hyoung-Gyu
    • Proceedings of the KSR Conference
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    • 2007.11a
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    • pp.313-336
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    • 2007
  • Unlike a conventional railway system, a high-speed rail system experiences various aerodynamic problems in tunnel sections. Trains running at a high speed in a small tunnel, when compared with the open field, face significant air pressure, resulting in reduced operating stability and fast change in pressure inside the tunnel. These phenomena further cause some unexpected problems such as the passengers onboard feeling an aural discomfort and an impulsive noise at the tunnel exit. To solve these problems, this paper introduces analysis of aerodynamic characteristics for determination of tunnel cross section. The optimum cross-section that satisfies the criteria of aural discomfort was reviewed through lots of numerical simulation analysis. Also, the pressure inside the passenger car of a train operating on Kyungbu HSR line was measured, and the pressure inside the tunnel and the micro-pressure waves at tunnel exit were measured at Hwashin 5 Tunnel. At the same time, a test of train operation model was performed and then the measurement results and test results were compared to verify that various parameters used as input conditions for the numerical simulations were appropriate.

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Microhabitat Assessment of Three Fish Species to Stream Order in Geumgang River Basin

  • Kang, Kyoung Ho;Hur, Jun Wook
    • Ecology and Resilient Infrastructure
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    • v.4 no.4
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    • pp.216-225
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    • 2017
  • We assessed the microhabitat conditions of three fish species (black shinner Pseudopungtungia nigra, striped shinner Pungtungia herzi, Korean shinner Coreoleuciscus splendidus) considering various stream order in the Geumgang River Basin. A total of 1,275 individuals were collected from 19 sites. And the microhabitat condition was assessed measuring flow velocity, water depth and substrate size at each site. The highest relative frequencies for P. herzi, C. splendidus and P. nigra were calculated 100% (n = 310), 78.9% (n = 784) and 47.3% (n = 181) respectively. P. herzi appeared in all streams, irrespective of their stream order; however, appearance in streams with the $2^{nd}$ order or lower was found to be scarcer than in the ones with the $3^{rd}$ order or higher. On the other hand, P. nigra and C. splendidus didn't appear in streams with the $2^{nd}$ order or lower. When it comes to P. nigra, the ones with 7 to 8 cm in length most frequently appeared. They inhabited streams, mainly, with 0.2 to $0.4m\;s^{-1}$ and 0.5 m in velocity and water depth, respectively. The three species all preferred runs as types of habitats with lots of coarse gravels-cobbles. P. herzi, the ones with 5 cm or shorter in length most frequently appeared. They inhabited streams, mainly, with 0 to $0.3m\;s^{-1}$ and 0.4 m in velocity and water depth, respectively. C. splendidus with 7 to 8 cm in length occupied the majority of them. They appeared in streams, mainly, with $0.9m\;s^{-1}$or higher and 0.3 m in velocity and water depth.

A Study of Computerized Industrial Hygiene Control System (작업환경관리 전산화에 관한 연구)

  • Lee, Song Kwon;Lee, Young Sei;Kim, Young Su;Kim, Yong Lae
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.4 no.1
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    • pp.117-126
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    • 1994
  • Some of the important and vital roles performed by the Health Care Center of Pohang Iron & Steel Co., Ltd.(POSCO) are the periodic monitoring of the work sites as well as regular medical check-ups for each workers to ensure both pleasant and safe working conditions and to protect employees' health. Pohang Steel Works, which has 42 plants, 26 facilities and 12,000 employees, has an annual crude steel production capacity of 9,670,000 using 24,500,000 ton of raw materials. We have measured lots of areal and personal working environment according to Occupational Safety and Health Law semiannually. All data collected on industrial hygiene is stored and managed by personal computer. The developed of a computerized industrial hygiene control system linked to the company's main computer system will provide efficient evaluation of the working environment as well as critical informations on employees' health. Development of this system had begun in May, 1992 and was completed in March, 1994. The computerized industrial hygiene control system can; 1. store industrial hygiene data, providing key pertinent to the diagnosis of occupational related illnesses, and if necessary, the basis for improving the working environment, 2. decide type and time of medical examination of each work for exposure to specific agents, and supply proper protection periodically, 3. prevent occupational related illnesses through evaluation of environmental and biological monitoring, and performance of epidemiological surveillance, 4. facilitate proper job placement through linking of industrial hygiene control and personnel information systems, 5. monitor job processes. levels of chemical agents used, and new agents introduced, 6. and increase productivity by saving time resulting from the implementation of the computerized sysyte,

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