• Fire Science and Engineering
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• v.29 no.6
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• pp.40-44
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• 2015

National and international standards for curtain wall glass are focused on wind pressure and insulation performance, but disasters such as fires and earthquakes are not considered. Failure of curtain wall glass during a fire in a skyscraper increases the loss of lives and property due to the spread of fire. Therefore, the fire resistance of curtain wall glass should be investigated, and technology to prevent glass failure should be developed to prevent fire damage due to spreading fire. It is important to predict the starting point of cracks and the cause of glass failure to prevent it effectively using the limited water in a skyscraper. In this study, double glazed glass was exposed to a radiator in an experiment performed to analyze the thermal characteristics. The results show that glass that was not directly exposed to high temperature and pressure was broken. To identify this failure case, numerical analysis was performed. Three glass specimens were installed in an ISO 9705 room and exposed to radiation using a radiator, and a thermocouple was used to measure the temperature on the surface of the glass. Widely used double glazed glass was analyzed for weakness to fire.

• Wind and Structures
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• v.16 no.4
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• pp.301-322
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• 2013

Recent major post-hurricane damage assessments in the United States have reported that the most common damages result from the loss of building roof coverings and subsequent wind driven rain intrusion. In an effort to look further into this problem, this paper presents a full-scale (Wall of Wind --WoW--) investigation of external and underneath wind pressures on roof tiles installed on a low-rise building model with various gable roofs. The optimal dimensions for the low-rise building that was tested with the WOW are 2.74 m (9 ft) long, 2.13 m (7 ft) wide, and 2.13 m (7 ft) high. The building is tested with interchangeable gable roofs at three different slopes (2:12; 5:12 and 7:12). The field tiles of these gable roofs are considered with three different tile profiles namely high (HP), medium (MP), and low profiles (LP) in accordance with Florida practice. For the ridge, two different types namely rounded and three-sided tiles were considered. The effect of weather block on the "underneath" pressure that develops between the tiles and the roof deck was also examined. These tests revealed the following: high pressure coefficients for the ridge tile compared to the field tiles, including those located at the corners; considerably higher pressure on the gable end ridge tiles compared to ridge tiles at the middle of the ridge line; and marginally higher pressure on barrel type tiles compared to the three-sided ridge tiles. The weather blocking of clay tiles, while useful in preventing water intrusion, it doesn't have significant effect on the wind loads of the field tiles. The case with weather blocking produces positive mean underneath pressure on the field tiles on the windward side thus reducing the net pressures on the windward surface of the roof. On the leeward side, reductions in net pressure to a non-significant level were observed due to the opposite direction of the internal and external pressures. The effect of the weather blocking on the external pressure on the ridge tile was negligible.

• The Korea Journal of Herbology
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• v.29 no.3
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• pp.27-33
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• 2014

Objectives : The aim of this study was to investigate the protective effect of extract of Thuja orientalis leaves (TOFE) against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity by inhibition of inflammation in in vitro and in vivo models of Parkinson's disease (PD). Methods : We evaluated the effect of TOFE against lipopolysaccharide (LPS)/1-methyl-4-phenylpyridinium ($MPP^+$) toxicity using nitric oxide (NO) assay, inducible NO synthase and cyclooxygenase 2 western blot, tyrosine hydroxylase and microglia activation immunohistochemistry (IHC) in BV2 cell, primary rat mesencephalic neurons, or C57BL/6 mice. We also evaluated the effect of TOFE in mice PD model induced by MPTP. C57BL/6 mice were treated with TOFE 50 mg/kg for 5 days and were injected intraperitoneally with four administrations of MPTP on the last day. We conducted behavioral tests and IHC analysis to see how TOFE affect MPTP-induced neuronal loss of dopaminergic neurons in substantia nigra pars compacta (SNpc) and striatum (ST) of mice. To assess the anti-inflammation effects, we carried out glial fibrillary acidic protein and macrophage-1 antigen integrin alpha M in IHC in SNpc and ST of mice. Results : In an in vitro system, TOFE decreasesd NO generations in BV2 cells. TOFE protected dopaminergic cells against LPS or $MPP^+$-induced toxicity in primary mesencephalic dopaminergic neurons. In vivo system, TOFE at 50 mg/kg treated group showed improved motor deteriorations than the MPTP only treated group and TOFE significantly protected striatal dopaminergic damage from MPTP-induced neurotoxicity in mice. Moreover, TOFE inhibited activation of astrocyte and microglia in SNpc and ST of the mice. Conclusions : We concluded that TOFE showed anti-parkinsonian effect by protection of dopaminergic neurons against MPTP toxicity through anti-inflammatory actions.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.49 no.4
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• pp.349-354
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• 2023

Sunscreen is a product that protects against ultraviolet rays by blocking and scattering ultraviolet rays, and has now become a daily necessity beyond cosmetics. Applying sunscreen is a common and easy way to prevent skin damage caused by ultraviolet rays. Due to its significance, the evaluation of sunscreen has evolved since its regulation by the FDA in 1978, progressing to standardized methods established by ISO. Additionally, to assess the loss of sunscreen due to activities such as water exposure or sweating, the Ministry of Food and Drug Safety in Korea and ISO have established protocols for evaluating the water-resistant sun protection factor (SPF). However, existing evaluations of water resistance have been mainly confined to test methods involving plain water, and methods accounting for the impact of seawater during activities like beach leisure, sports, and recreation are yet to be established. Based on the existing guidelines for testing the water-resistant UV protection index, this study compared the water-resistant UV protection index in water, artificial seawater (salt water) and natural seawater (sea water) to evaluate the UV protection index in real-world situations such as marine leisure, sports, and leisure activities. Through these results, we were able to compare the differences between water resistance sun protection index tests in ordinary water, artificial seawater, and natural seawater, and suggest a method for water resistance sun protection index tests using natural seawater.

• Journal of the Korea Concrete Institute
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• v.25 no.4
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• pp.447-455
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• 2013

In this study, reinforced concrete slabs with steps were experimentally studied to analyze their structural performance and to suggest reinforcing details in the step. Because the stepped slabs may behave very poorly in terms of bending strength, stiffness, deflection, cracking, etc., the study is aimed to suggest proper reinforcing details such that the same bending strength is obtained as that without steps. The bending strengths of 12 test specimens with a variety of different reinforcing detail types or other parameters were compared with each other. The specimen without any additional reinforcement in the step had a very low bending strength and significant damage, and the specimens with diagonal reinforcements in the step showed substantial early cracks, experienced hinging of the step, and had a substantial loss of the bending strength. In contrast, the specimens with a combination of U-bars, reversed U-bars, L-bars, and reversed L-bars performed very well and almost reached to 100% of the slab bending strength. The U-bars and reversed U-bars were effective in controling the diagonal cracks, while the L-bars and reversed L-bars were effective in preventing from yielding of slab reinforcement near the step.

• Applied Chemistry for Engineering
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• v.21 no.6
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• pp.664-669
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• 2010

The forest area of domestic is 6370304 ha, which covers 70% of the whole country, and especially Gangwon-do is remarkably larger than other Province. A thick forest of the country has the most basic component among other natural environments as well as it has invaluable worth to human being such as scientific research and educational value. However due to the breakout of forest fire since 1990s, the loss of trees, destruction of natural environment and ecology, economic damage have been occurring and its scale also has become larger. The causes of becoming larger in scale are resulted from forest components which mainly consist of needle leaf trees, wide leaf trees, fallen leaves, herbaceous plants so that it has been a direct cause for forest fire. However, few research on combustion and pyrolysis characteristics has been done in domestic and abroad. The study on the combustion and pyrolysis for Pinus densiflora which are typical needle leaf trees has been tried using TGA. Pinus desiflora started to being ignited at around $162^{\circ}C$ and pyrolysis was done at around $197^{\circ}C$. Differential method was applied to calculate activation energy and frequency factor according to the variation of conversion. Activation energy in pyrolysis was increased from 79 kJ/mol to 487 kJ/mol with increasing conversion and average activation energy was 195 kJ/mol. The activation energy in combustion was decreased from 148 kJ/mol to 133 kJ/mol.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.26 no.3
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• pp.131-139
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• 2014

Infra-gravity waves (IGWs) with a period of 1~3 minutes are a factor that directly influences the motion analysis of moored ships inside a harbor and longshore sediment transport analysis. If significant levels of IGWs from far seas are transferred to a harbor and amplified, they may cause downtime of large ships and induce economic loss. In this study, transfer characteristics of the IGWs intruding from outside to inside Pohang New Harbor were analyzed using statistical analysis and transfer function of wave data measured at both outside and inside the harbor for around 5 years. Transfer characteristic analysis was limited to events where IGWs had wave heights above 0.1 m. The wave height distribution of inside the harbor was similar to that of outside the harbor, while the wave period variance of the former was larger than that of the latter. The parameters of the transfer function was optimally estimated according to each event. The estimated average RMS error of the wave height inside the harbor was around 0.013 m. The estimated parameters had a strong correlation with the linear combination information of IGW wave height, period, and direction (R = 0.95). The transfer function suggested in this study can quickly and easily estimate information on IGWs inside the harbor using IGW information predicted beforehand, and is expected to reduce damage due to unexpected restrictions on harbor usage.

• Korean Security Journal
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• no.36
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• pp.293-316
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• 2013

Today's high-rise buildings are increasing concern about the safety and evacuation of people related to the fire and threat from outside. Terrorism breaking out in high-rise buildings, a symbol of the national economy results in a number of casualties, economic loss, social fear and damage to national status. That's why high-rise building has also emerged as a target of major terrorist attacks, compared to other types of buildings. We have 54 high-rise buildings in 15 regions over the country. The Ministry of Land, Infrastructure and Transport and Seoul Metropolitan Government have offered the guidelines to prevent terrorist attacks toward high-rise buildings. Since the 9/11 terrorist attacks, the U.S. Federal Emergency Management Agency (FEMA) has developed and taken advantage of the Risk Management Manual Series. According to this manual, pre-assessment is conducted for the prevention of terrorism and particularly in FEMA 455, risk of the surrounding areas, vulnerability, possibility from terrorist attacks are checked. After the check, experts classify the risk of terrorist attacks toward the high-rise buildings and according to the risk classification, architects, security experts and structure engineers can carry out terrorism prevention program for high-rise buildings. The U.K. NaCTSO has also offered the terrorism prevention guidelines. Therefore, the Ministry of Land, Infrastructure and Transport and Seoul Metropolitan Government should make more concrete guidelines for high-rise buildings such as what U.S. FEMA and U.K. NaCTSO implement, including prior evaluation technique for terrorism risk.

• The Journal of Korean Medicine
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• v.30 no.3
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• pp.1-14
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• 2009

Objectives : Alzheimer's disease (AD) is characterized by neuronal loss and extracellular senile plaque. Moreover, the cellular actions of ${\beta}$-amyloid (A${\beta}$ play a causative role in the pathogenesis of AD. This study was designed to determine whether Woo-Gui-Um, a commonly used Korean herbal medicine, has the ability to protect cortical and hippocampal neurons against A${\beta}_{25-35}$ neurotoxicity Methods : In the present study, the authors investigated the preventative effects of the water extract of Woo-Gui-Um in a mouse model of AD. Memory impairment was induced by intraventricularly (i.c.v.) injecting A${\beta}_{25-35}$ peptides into mice. Woo-Gui-Um extract was then administered orally (p.o.) for 14 days. In addition, A${\beta}_{25-35}$ toxicity on the hippocampus was assessed immunohistochemically, by staining for Tau, MAP2, TUNEL, and Bax, and by performing an in vitro study in PC12 cells. Results : Woo-Gui-Um extract had an effect to improve learning ability and memory score in the water maze task. Woo-Gui-Um extract had significant neuroprotective effects in vivo against oxidative damage and apoptotic cell death of hippocampal neurons caused by i.c.v. A${\beta}_{25-35}$. In addition, Woo-Gui-Um extract was found to have a protective effect on A${\beta}_{25-35}$-induced apoptosis, and to promote neurite outgrowth of nerve growth factor (NGF)-differentiated PC12 cells. Conclusions : These results suggest that Woo-Gui-Um extract reduces memory impairment and Alzheimer's dementia via an anti-apoptotic effect and by regulating Tau and MAP2 in the hippocampus.

• Journal of Korean Society of Disaster and Security
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• v.7 no.2
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• pp.17-24
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• 2014

Recently, many accidents occur frequently because sprinklers aren't installed or don't work right when there are outbreak of fire in houses and aggregate buildings. Therefore, they can result in damage for humans and loss of property. Sprinklers are the most appropriate which can extinguish buildings' fire in the initial stages. Through lack of legal system, in domestic cases, sprinklers cannot operate their inherent performance. Domestic standard simply classifies installation objects according to types of business and forms of buildings, also divides into uses and floors of buildings. Especially it only regulates that sprinklers must be installed every floors in particular fire buildings that have more than eleven floors. While it doesn't need to install sprinklers below ten floors, so we are threatened the safety. In this study, we derived causes and implications by analyzing concepts of sprinklers facilities, installation standards in domestic and foreign legal system, and recent cases that expanded damages in fire accidents because of weak point of installation and control standards. In domestic cases, as a result, government has to provide an institutional strategy and law that regulate duty to install sprinklers to all aggregate buildings regardless of floors in terms of new buildings. Also, if someone who has existing buildings wanted to install them, government would guarantee subsidy to encourage installation. In addition, government supervises fire-fighting activities when there are fire by compensating standards about regular inspection by a qualified technician, operation and maintenance of sprinklers as well as reinforcement of administrative criteria.