• Title/Summary/Keyword: Loss and damage

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Fracture Characteristics of Ductile Fiber Reinforced Cement based Composites by Collision of Steel Projectile (비상체의 충돌에 의한 고인성 섬유보강 시멘트복합체의 파괴특성)

  • Nam, Jeong-Soo;Kim, Gyu-Yong;Kim, Hong-Seop;Kim, Jung-Hyun;Han, Sang-Hyu
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.19 no.4
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    • pp.92-100
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    • 2015
  • The aim of this study is to evaluate the fracture characteristics of ductile fiber reinforced cement based composites with 1.5 volume ratio of polyvinyl alcohol and steel fiber by high velocity impact of steel projectile. We used gunpowder impact facility to evaluate the fracture characteristics of ductile fiber reinforced cement based composites by collision of steel projectile, and the impact velocity was from about 150 to 1,000m/s. The results of evaluation on the fracture characteristics of ductile fiber reinforced cement based composites were penetration grade, which is the kinetic energy more than three times of no-fiber reinforced specimen (Plain). In addition, ductile fiber reinforced cement based composites did not occurred critical damage other than the debris. In the case of mass loss, Plain specimen was proportional to kinetic energy of steel projectile, while ductile fiber reinforced cement based composites was not significantly affected by kinetic energy of steel projectile. In particular, this tendency had a close relationship with the fracture characteristics of back side of specimens, and the scabbing inhibiting efficiency of PVA specimen was higher than S specimen. In the results of verifying relationship between front and back side calculated by local damage, scabbing occurred at the region close to the back side in the ductile fiber reinforced cement based composites unlike Plain specimen. Thus, in this study, we examined principal fracture behaviors of ductile fiber reinforced cement based composites under collision of steel projectile, and verified that impact resistance performance was improved as compared to Plain specimen.

Kaempferol Activates G2-Checkpoint of the Cell Cycle Resulting in G2-Arrest and Mitochondria-Dependent Apoptosis in Human Acute Leukemia Jurkat T Cells

  • Kim, Ki Yun;Jang, Won Young;Lee, Ji Young;Jun, Do Youn;Ko, Jee Youn;Yun, Young Ho;Kim, Young Ho
    • Journal of Microbiology and Biotechnology
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    • v.26 no.2
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    • pp.287-294
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    • 2016
  • The effect of kaempferol (3,5,7,4-tetrahydroxyflavone), a flavonoid compound that was identified in barnyard millet (Echinochloa crus-galli var. frumentacea) grains, on G2-checkpoint and apoptotic pathways was investigated in human acute leukemia Jurkat T cell clones stably transfected with an empty vector (J/Neo) or a Bcl-xL expression vector (J/Bcl-xL). Exposure of J/Neo cells to kaempeferol caused cytotoxicity and activation of the ATM/ATR-Chk1/Chk2 pathway, activating the phosphorylation of p53 (Ser-15), inhibitory phosphorylation of Cdc25C (Ser-216), and inactivation of cyclin-dependent kinase 1 (Cdk1), with resultant G2-arrest of the cell cycle. Under these conditions, apoptotic events, including upregulation of Bak and PUMA levels, Bak activation, mitochondrial membrane potential (Δψm) loss, activation of caspase-9, -8, and -3, anti-poly (ADP-ribose) polymerase (PARP) cleavage, and accumulation of apoptotic sub-G1 cells, were induced without accompanying necrosis. However, these apoptotic events, except for upregulation of Bak and PUMA levels, were completely abrogated in J/Bcl-xL cells overexpressing Bcl-xL, suggesting that the G2-arrest and the Bcl-xL-sensitive mitochondrial apoptotic events were induced, in parallel, as downstream events of the DNA-damage-mediated G2-checkpoint activation. Together these results demonstrate that kaempferol-mediated antitumor activity toward Jurkat T cells was attributable to G2-checkpoint activation, which caused not only G2-arrest of the cell cycle but also activating phosphorylation of p53 (Ser-15) and subsequent induction of mitochondria-dependent apoptotic events, including Bak and PUMA upregulation, Bak activation, Δψm loss, and caspase cascade activation.

SUPEROXIDE DISMUTASE - AND CATALASE - ACTIVITY IN BLOOD PLASMA AND RED BLOOD CELLS IN PERIODONTITIS (치주염 환자의 혈장과 적혈구내 S.O.D와 Catalase 활성도에 관한 연구)

  • Hwang, Seung-Hwan;Kim, Byung-Ok;Han, Kyung-Yoon
    • Journal of Periodontal and Implant Science
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    • v.25 no.1
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    • pp.167-178
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    • 1995
  • It has been believed that the increased release of free oxygen radicals and their tissue damaging potency might be a contributing factor in the pathogenesis of periodontal disease. Antioxidant enzymes such as superoxide dismutase(SOD) and catalase can protect the tissue damage from the free oxygen radicals($O_2^-,H_2O_2$, and $OH^-$). In order to investigate the SOD- and catalase - activity in the blood plasma and red blood cells(RBCs) of the patients with perodontitis, 19 male periodontitis patients($25{\sim}35$ years old) who had good general health, more than 10 teeth with severely inflamed gingiva, attachment loss more than 6mm and bone loss were selected as periodontitis group, and 13 male volunteers($22{\sim}29$ years old) with good general and periodontal health were selected as normal group. After blood plasma and RBC were separated from peripheral blood of 2ml collected from antecubital vein of each subject, SOD- activity in blood plasma and RBCs was measured by the same method that Paoletti et al. did, and catalase - activity in RBC was measured by the same method that Beers et al, did. The difference of SOD- and catalase - activity between the normal and the periodontitis groups was statistically analyzed by Student t-test with SPSS/PC program.The results were as follows : 1. SOD activity in blood plasma was significantly lower in the periodontitis group($1.986{\pm}0.893$) than in the normal group($3.324{\pm}1.044$)(p<0.05). 2. There was no statistical significance in the difference of SOD- activity in RBCs between the periodontitis group($7.753{\pm}3.206$) and the normal group($8.116{\pm}1.192$)(p$242.8{\pm}45.6$) than in the normal group($280.2{\pm}32.6$)(p

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A Comparative Analysis of Fishery and Marine Environment-related Policies on Estimated Amount of Fishery Debris Caused by Fishing (조업기인 어업쓰레기 발생추정량에 대한 어업 및 해양환경 관련 정책 비교분석)

  • Seong, Eun-hye;Kim, Kyung-shin
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.28 no.6
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    • pp.906-917
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    • 2022
  • This study aimed to compare differences according to categories of fishery and marine environmental policies for the (estimated) amount of fishery waste generated by fishing, and to analyze the correlation between associated independent and dependent variables. The independent variables were divided into three dif erent sectors. The first sector included precautionary policies that observed eco-friendly fishing support program, institutional prevention activities, and physical barriers installation. The second sector with the current management policies included the relevant vessel operations, establishment of fishery order, fishery restructuring, and fishery ground clean-up. Thirdly, post-response policies comprised the litter purification from river to shoreline, the collection and removal of marine, sedimentary, and floating debris, purchasing salvaged debris generated while fishing, fishery waste disposal, and repairing damage caused by marine litter. The indicator used was the settlement amount by each program. The dependent variable was the estimated amount of fishery waste and the indicator was the sum of the loss of traps and gill nets and the loss of their appendages. According to the results of Kruskal-Wallis Test, the estimated amount of fishery waste was highest in the East Sea in terms of sea area and the highest in the Si(city) according to basic local municipality. The settlement amount related to the marine environment services was largest in the Gun(county). Further, there were significant differences between Gun(county) and the other regions(Si(city) and Gu(autonomous district)) with respect to most variables. The variables related to the estimated amount of fishery debris were the project purchasing salvaged debris generated while fishing and fishery waste disposal program in the post-response policies.

Isolation and Identification of Fungi Associated with Decay of Quercus mongolica (신갈나무의 부후에 관여하는 곰팡이 분리 및 동정)

  • HAM, Youngseok;AN, Ji-Eun;LEE, Soo Min;CHUNG, Sang-Hoon;KIM, Sun Hee;PARK, Mi-Jin
    • Journal of the Korean Wood Science and Technology
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    • v.49 no.3
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    • pp.234-253
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    • 2021
  • The Quercus mongolica has a high utilization value in industrial economic sector. The species is distributed throughout Korea, however, the damage caused by deterioration such as discoloration and decay is severe. For this reason, the deterioration of Q. mongolica is an obstacle to its use as wood, but research on deterioration factors is insufficient. In this study, we focused on fungi as a factor influencing the deterioration of Q. mongolica, and isolated and identified the fungi from the deteriorated Q. mongolica. In additions, in order to confirm whether the identified fungi actually affects wood deterioration, enzyme activities of the identified fungi were evaluated and related mass loss of wood treated with the fungi was measured by wood decay test. As a result of sequencing analysis using the ITS region of the genomic DNA of the fungi isolated from Q. mongolica, Mucor circinelloides, Cunninghamella elegans, and Umbelopsis isabellina 3 species belonging to Mucoromycota phylum, and Ophiostoma piceae and Aureobasidium melanogenum 2 species belonging to Ascomycota phylum were identified. These five fungi had enzyme (i.e. cellulase, laccase) activities related to wood decay and reduced the mass of heartwood and sapwood of Q. mongolica in practice. In particular, O. piceae and A. melanogenum, which have both cellulase and laccase activities, showed 6.9% and 1.5% mass loss, respectively. These results indicated that five fungi identified in this study influence the deterioration of Q. mongolica and are wood decaying fungi for Q. mongolica potentially.

Durability assessments of limestone mortars containing polypropylene fibres waste

  • Bendjillali, Khadra;Boulekbache, Bensaid;Chemrouk, Mohamed
    • Advances in concrete construction
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    • v.10 no.2
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    • pp.171-183
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    • 2020
  • The main objective of this study is the assessment of the ability of limestone mortars to resist to different chemical attacks. The ability of polypropylene (PP) fibres waste used as reinforcement of these concrete materials to enhance their durability is also studied. Crushed sand 0/2 mm which is a fine limestone residue obtained by the crushing of natural rocks in aggregates industry is used for the fabrication of the mortar. The fibres used, which are obtained from the waste of domestic plastic sweeps' fabrication, have a length of 20 mm and a diameter ranging between 0.38 and 0.51 mm. Two weight fibres contents are used, 0.5 and 1%. The durability tests carried out in this investigation included the water absorption by capillarity, the mass variation, the flexural and the compressive strengths of the mortar specimens immersed for 366 days in 5% sodium chloride, 5% magnesium sulphate and 5% sulphuric acid solutions. A mineralogical analysis by X-ray diffraction (XRD) and a visual inspection are used for a better examination of the quality of tested mortars and for better interpretation of their behaviour in different solutions. The results indicate that the reinforcement of limestone mortar by PP fibres waste is an excellent solution to improve its chemical resistance and durability. Moreover, the presence of PP fibres waste does not affect significantly the water absorption by capillarity of mortar nether its mass variation, when exposed to chloride and sulphate solutions. While in sulphuric acid, the mass loss is higher with the presence of PP fibres waste, especially after an exposure of 180 days. The results reveal that these fibres have a considerable effect of the flexural and the compressive behaviour of mortar especially in acid solution, where a reduction of strength loss is observed. The mineralogical analysis confirms the good behaviour of mortar immersed in sulphate and chloride solutions; and shows that more gypsum is formed in mortar exposed to acid environment causing its rapid degradation. The visual observation reveals that only samples exposed to acid attack during 366 days have showed a surface damage extending over a depth of approximately 300 ㎛.

A Study on the Optimal Allocation Model of the Korean Maritime SAR Fleet (우리나라 해상 수색.구조선의 최적배치에 관한 연구)

  • 장운재;금종수;신철호
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2003.05a
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    • pp.35-41
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    • 2003
  • The Korea Maritime Police Agency(KMPA) is the national maritime Search and Rescue (SAR) authority with the responsibility to promote an efficient organization of SAR services and to coordinate the conduct of SAR operations within the Korean Search and Rescue Region(SRR). The maritime SAR operations shall provide an adequate and effective search and rescue services to minimize the loss of life, injury property damage or loss by rendering aid to persons in distress and property in the marine environment. The essence of a successful search and rescue operation is the speed with which it is planned and carried out because survivors who need assistance and whose chances of survival diminish rapidly with time. This paper aims to propose an optimal allocation model of maritime SAR fleet in view of minimizing the search and rescue time. When maritime accidents occur, rescue units have to reach to the distress scene within the specified time. For this. SAR units must be redeployed to an advanced base so that Rescue Units(RU) can reach to the scene of distress in the shortest possible time. The Korean maritime SRR is divided into 180 sub-areas in consideration of an operational and technical ability of SAR units The suggested model is verified through an empirical application to the Korean maritime SRR. And also the Rescue Vessels(RV) required is estimated for each Rescue Co-ordination Center(RCC).

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EFFECTS OF CONDENSED PHOSPHATES ON THE DENATURATION OF ALASKA POLLACK MUSCLE DURING REFREEZING AN COLE STORAGE (재동결 명태육의 냉동변성에 미치는 축합인산염처리의 효과에 대하여)

  • KANG Yeung-Joo;PARK Yeung-Ho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.8 no.1
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    • pp.37-45
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    • 1975
  • The present study was ,conducted to evaluate the effects of condensed phosphates on the refeezing damage of Alaska pollack muscle. The fillets were dipped in such solution as 5 and $10\%$ sodium polyphosphate, 1 and $5\%$ mixture of sodium polyphosphate and sodium pyrophosphate (1:1, w/w) for 1 and 5 minutes, respectively, before refreezing. And fillets were frozen at $27^{\circ}C\~28^{\circ}C$ and stored for 15 days at $-18^{\circ}\~-20^{\circ}$. The degree of denaturation was estimated by determining amounts of drip relased, content of total solids, nitrogen, and DNA in the drip an cooking-weight-loss. Phosphorus absorbed in the muscle was also determined. Phosphorus absorbed in the fillets treated with loft solution of sodium polyphosphate for 5 minutes amounted to 101 mg/100g muscle as $P_2O_5$. The absorption was dependent on tile concentration of treating solution rather than on the dipping time. The increase of phosphorus absorption seemed to affect to reduction of drip. Among the treating conditions, $10\%$, 5 minutes and $10\%$ 1 minute with sodium polyphosphate appeared most effective ones on drip reduction. The effect of $5\%$, minutes with the mixture of sodium polyphosphate and sodium pyrophosphate did not show so benefitable effect in refrozen fillets. As a tendency total solids, nitrogen, and DNA in tile drip varied proportionally to the amount of drip released. And the content of DNA was lower than the amount. Treatment, at higher the concentration and longer the dipping time, resulted in the lower cooking-weight-loss and the better quality on organoleptic test of thawed fillets.

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Full mouth rehabilitation in patient with loss of vertical dimension and deep bite due to tooth wear (치아 마모로 인한 수직고경감소와 과개교합을 가진 환자의 완전 구강 회복 증례)

  • Chae, Hyun-Seok;Jeon, Bo-Seul;Lee, Jung-Jin;Ahn, Seung-Geun;Seo, Jae-Min
    • The Journal of Korean Academy of Prosthodontics
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    • v.57 no.4
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    • pp.405-415
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    • 2019
  • Excessive tooth wear can cause irreversible damage to the occlusal surface and can alter the anterior occlusal relationship by destroying the structure of the anterior teeth needed for esthetics and proper anterior guidance. The anterior deep bite is not a morbid occlusion by itself, but it may cause problems such as soft tissue trauma, opposing tooth eruption, tooth wear, and occlusal trauma if there are no stable occlusal contacts between the lower incisal edge against its upper lingual surface. The most important goal of treatment is to form stable occlusal contact in centric relation. In this case report, patients with decrease in vertical dimension and anterior deep bite due to maxillary posterior tooth loss and excessive tooth wear were treated full mouth rehabilitation with increased vertical dimension to regain the space for restoration and improve anterior occlusal relationship and esthetics. The functional and aesthetic problems of the patient could be solved by the equal intensity contact of all the teeth in centic relation (CR), anterior guidance in harmony with the functional movement, and restoration of the wear surface beyond the enamel range.

Voice Changes after Thyroidectomy Without Recurrent Laryngeal Nerve Injury (반회후두신경 손상을 동반하지 않은 갑상선 절제술 후 음성 변화)

  • Choi, Jee-Sun;Jeong, Jong-In;Jang, Min-Seok;Son, Young-Ik
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.21 no.1
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    • pp.37-41
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    • 2010
  • Background and Objectives : Transient minor voice changes after thyroidectomy are not infrequent complaints even in cases without any evidence of recurrent laryngeal nerve damage. However, clinical course, diagnosis and management of such voice changes are not fully understood. This study aimed to evaluate the clinical characteristics of minor voice changes after thyroidectomy. We also tried to assess the significance and feasibility of superior laryngeal nerve monitoring and to find out the optimal evaluation tools for such voice changes after thyroidectomy. Materials and Method : Nine adult patients who received total thyroidectomy without evidence of recurrent laryngeal nerve injury were enrolled for this prospective study. Voice evaluations were performed preoperatively and 3 months postoperatively ; acoustic analyses including voice range profile, aerodynamic study, stroboscopic evaluation and subjective voice assessment with questionnaires. The external branch of superior laryngeal nerve was monitored by nerve stimulator after ligation of superior thyroidal vessels. Results: Four of nine patients complained their voice change at 3 months after the surgery. Three of them reported complete recovery of their voice at 6 months after the surgery. Acoustic analysis revealed significant decrease in their phonatory range especially with high tone loss. Questionnaires related to singing was more sensitive than previously well-known "voice handicap index". Stimulation of the superior laryngeal nerve was feasible in most of the cases (94.4%), but it failed to show any correlation with minor voice changes after thyroidectomy. Conclusion : Minor voice changes were not rare events during the first 6 month after thyroidectomy. Decrease in phonatory range with high tone loss and therefore, discomfort in singing was the most common finding. Superior laryngeal monitoring was feasible but it was not a sensitive tool for the prediction of minor voice change after thyroidectomy.

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