• Journal of the Korean Society of Marine Environment & Safety
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• v.22 no.3
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• pp.259-267
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• 2016

The study performs a risk analysis on container ship accidents using accident data collected over the six years from 2006 to 2011, presents the resulting risk level, and suggests three risk mitigation measures to reduce the overall risk, for the safer operation of container ships. More specifically, starting from the initial accident of collision, we developed 13 different accident scenarios using event tree analysis based on which the overall risk level was obtained and presented as a FN curve. Since diverse human factors are the main cause of most of the ship accidents, our study focuses on the effect of reducing human causes on the resulting risk level. For the research we considered the injuries for the calculation of fatality with the help of MAIS. The results show that collision was the main type of accident, accounting for 62 % of all accidents, and the measures employed were proven to be effective in the sense that the risk level was much lowered and the average number of fatalities was also reduced. With more data accumulated, more precise risk level will be calculated with which the practical risk mitigating measures will be also developed. For future study, economic loss and environmental damage as consequences need to be considered.

• Journal of the Korean Ceramic Society
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• v.52 no.1
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• pp.48-55
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• 2015

Hardened cement-based materials exposed to the high temperatures of a fire are known to experience change in the pore structure as well as microstructural changes that affect their mechanical properties and tend to reduce their durability. In this experimental investigation, hardened Portland cement pastes were exposed to elevated temperatures of 200, 400, 600, 800, and $1000^{\circ}C$ for 60 minutes, and the resulting damage was studied by thermogravimetry (TG), mercury intrusion porosimetry (MIP) and density measurements. These results revealed that the residual compressive strength is increased at temperatures greater than $400^{\circ}C$ due to a small pore size of 3 nm and/or rehydration of the dehydrated cement paste. However, a loss of the residual strength occurs at temperatures exceeding 500 and $600^{\circ}C$. This can be attributed to the decomposition of hydrates such as portlandite and to an increase in the total porosity.

• Structural Engineering and Mechanics
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• v.31 no.1
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• pp.11-24
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• 2009

In China, the oil and natural gas resources of Bohai Bay are mainly marginal oil fields. It is necessary to build both ice-resistant and economical offshore platforms. However, risk is involved in the design, construction, utilization, maintenance of offshore platforms as uncertain events may occur within the life-cycle of a platform under the extreme ice load. In this study, the optimum design model of the expected life-cycle cost for ice-resistant platforms based on cost-effectiveness criterion is proposed. Multiple performance demands of the structure, facilities and crew members, associated with the failure assessment criteria and evaluation functions of costs of construction, consequences of structural failure modes including damage, revenue loss, death and injury as well as discounting cost over time are considered. An efficient approximate method of the global reliability analysis for the offshore platforms is provided, which converts the implicit nonlinear performance function in the conventional reliability analysis to linear explicit one. The proposed life-cycle optimum design formula are applied to a typical ice-resistant platform in Bohai Bay, and the results demonstrate that the life-cycle cost-effective optimum design model is more rational compared to the conventional design.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.29 no.10 s.241
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• pp.1384-1391
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• 2005

Damage often occurs on the surface of railway wheels due to wheel-rail contact fatigue. It should be removed before reaching wheel failure, because wheel failure can cause derailment with loss of life and property. The increase or decrease of the contact fatigue lift by the metal removal of the contact surface were investigated by many researchers, but they have not considered initial residual stress and traction force. The railway wheel has the initial residual stress formed during the manufacturing process, and the residual stress is changed by thermal stress induced by braking. The traction force and residual stress are operated on wheels of locomotive and electric motor vehicle. In this study, the effect of metal removal depth on the contact fatigue life for a railway wheel has been evaluated by applying lolling contact fatigue test. The effect of the traction force and metal removal on the contact fatigue life has been estimated by finite element analysis. It has been found that the initial residual stress determines the amount of metal removal depth if the traction coefficient is less than 0.15. If the traction coefficient is greater than 0.2, however, the amount of metal removal depth is independent on the intial residual stress.

• Journal of the Korean Society of Hazard Mitigation
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• v.8 no.2
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• pp.83-90
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• 2008

Social infrastructures have been built when the growth of economy in Korea significantly increases in 1960s. Nowadays, these infrastructures have been aged with an inappropriate maintenance and management and the citizens have rare recognition for human disasters. In addition, the government has law or regulations responding to human disasters but these are not complementary. Since these human disasters have been issued as social problems and have induced social and economic loss, the improvement schemes for human disasters are currently being demanded. In this study, the case histories of damages and improvement schemes with respect to the types of damages for human disasters are comprehensively investigated.

• Journal of Surface Science and Engineering
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• v.49 no.4
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• pp.344-348
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• 2016

Stainless steel is widely applied in many industrial fields due to its excellent anti-corrosion and durability characteristics. However, stainless steel is very vulnerable to cavitation attack caused by high speed flow of fluid in the chloride environments such as marine environment. These conditions promote intergranular corrosion and cavitation-erosion, leading to degradation of the structural integrity and service life. In order to prevent these problems, the stabilized stainless steel is applied to the offshore and shipbuilding industries. In this study, Ti was added to 19%Cr-9%Ni as the stabilizer element with different concentrations (0.26%, 0.71%), and their durabilities were evaluated with cavitation-erosion experiment by a modified ASTM G32 method. The microstructural change was observed with the stabilizer element contents. The result of the observation indicated that the amount of carbide precipitation was decreased and its size became finer with increasing Ti content. In the cavitation-erosion experiment, both weight loss and surface damage depth represented an inverse proportional relationship with the amount of Ti element. Consequently, the stainless steel containing 0.71% of Ti had excellent durability characteristics.

• The Journal of Pediatrics of Korean Medicine
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• v.35 no.3
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• pp.128-137
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• 2021

Objective The purpose of this study was to confirm the effectiveness of coptidis rhizoma extract-ceramide complex on skin barrier, transepidermal water loss (TEWL) and pH reduction, and inflammation of the skin. Methods Coptidis rhizoma extract-ceramide complex was applied in 6-week-old Balb/C mice after dermatitis was induced. To confirm the skin condition changes, TEWL and pH were observed, and filaggrin in the stratum corneum of the skin was observed. Kallikrein-related peptidase (KLK) 7, Protease activated receptor (PAR)-2, Thymic stromal lymphopoietin (TSLP), and IL-4 were observed in the stratum corneum to confirm the changes in the inflammatory response. Results Filaggrin positive reaction was increased in the experiment group compared to the control group. TEWL and pH were lower in the experiment group compared to the control group. KLK7, PAR2, TSLP, and IL-4 positive responses were decreased in the experiment group compared to the control group. Conclusions It was confirmed that the coptidis rhizoma extract-ceramide complex can relieve the inflammatory response of atopic dermatitis by restoring the skin lipid barrier damage.

• The Journal of Korean Institute of Information Technology
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• v.17 no.9
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• pp.11-17
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• 2019

In recent years, damage and loss of life and property have been occurred frequently due to swelling waves in the East Sea. Swelling waves are not easy to predict because they are caused by various factors. In this research, we build a model for predicting the swelling waves occurrence in the East Coast of Korea using machine learning technique. We collect historical data of unloading interruption in the Pohang Port, and collect air pressure, wind speed, direction, water temperature data of the offshore Pohang Port. We select important variables for prediction, and test various machine learning prediction algorithms. As a result, tide level, water temperature, and air pressure were selected, and Random Forest model produced best performance. We confirm that Random Forest model shows best performance and it produces 88.86% of accuracy

• Journal of Microbiology and Biotechnology
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• v.32 no.3
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• pp.348-354
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• 2022

Recent studies have shown that probiotics have health-promoting effects, particularly intestinal immune modulation. In this study, we focused on the immunomodulatory properties of Latilactobacillus curvatus BYB3, formerly called Lactobacillus curvatus, isolated from kimchi. In a mouse model of 14-day dextran sulfate sodium (DSS)-induced colitis, treatment with L. curvatus BYB3 significantly decreased the disease activity index, colon length, and weight loss. Moreover, histological analyses showed that L. curvatus BYB3 protected the structural integrity of the intestinal epithelial layer and mucin-secreting goblet cells from DSS-induced damage, with only slight infiltration by immune cells. To evaluate the molecular mechanisms underlying L. curvatus BYB3-driven inhibition of interleukin 6 production, possible in vivo anti-inflammatory effects of L. curvatus BYB3 were examined in the same mouse model. In addition, significantly lower levels of IL-6 and tumor necrosis factor receptor 1 upregulation were seen in the DSS+BYB3 group (compared to that in the DSS group). These results indicate that L. curvatus BYB3 exhibits health-promoting effects via immune modulation; and therefore, it can be used to treat various inflammatory diseases.

• The Korean Journal of Physiology and Pharmacology
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• v.25 no.4
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• pp.297-305
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• 2021

Luteolin, a sort of flavonoid, has been reported to be involved in neuroprotective function via suppression of neuroinflammation. In this study, we investigated the protective effect of luteolin against oxidative stress-induced cellular senescence and its molecular mechanism using hydrogen peroxide (H₂O₂)-induced cellular senescence model in House Ear Institute-Organ of Corti 1 cells (HEI-OC1). Our results showed that luteolin attenuated senescent phenotypes including alterations of morphology, cell proliferation, senescence-associated 𝛽-galactosidase expression, DNA damage, as well as related molecules expression such as p53 and p21 in the oxidant challenged model. Interestingly, we found that luteolin induces expression of sirtuin 1 in dose- and time-dependent manners and it has protective role against H₂O₂-induced cellular senescence by upregulation of sirtuin 1 (SIRT1). In contrast, the inhibitory effect of luteolin on cellular senescence under oxidative stress was abolished by silencing of SIRT1. This study indicates that luteolin effectively protects against oxidative stress-induced cellular senescence through p53 and SIRT1. These results suggest that luteolin possesses therapeutic potentials against age-related hearing loss that are induced by oxidative stress.