• 제목/요약/키워드: Long-term dynamics

검색결과 279건 처리시간 0.026초

Effects of treadmill exercise on the regulatory mechanisms of mitochondrial dynamics and oxidative stress in the brains of high-fat diet fed rats

  • Koo, Jung-Hoon;Kang, Eun-Bum
    • 운동영양학회지
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    • 제23권1호
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    • pp.28-35
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    • 2019
  • [Purpose] The purpose of this study was to investigate the effects of treadmill exercise on oxidative stress in the hippocampal tissue and mitochondrial dynamic-related proteins in rats fed a long-term high-fat diet (HFD). [Methods] Obesity was induced in experimental animals using high fat feed, and the experimental groups were divided into a normal diet-control (ND-CON; n=12), a high fat diet-control (HFD-CON; n=12) and a high fat diet-treadmill exercise (HFD-TE; n=12) group. The rats were subsequently subjected to treadmill exercise (progressively increasing load intensity) for 8 weeks (5 min at 8 m/min, then 5 min at 11 m/min, and finally 20 min at 14 m/min). We assessed weight, triglyceride (TG) concentration, total cholesterol (TC), area under the curve, homeostatic model assessment of insulin resistance, and AVF/body weight. Western blotting was used to examine expression of proteins related to oxidative stress and mitochondrial dynamics, and immunohistochemistry was performed to examine the immunoreactivity of gp91phox. [Results] Treadmill exercise effectively improved the oxidative stress in the hippocampal tissue, expression of mitochondrial dynamic-related proteins, and activation of NADPH oxidase (gp91phox) and induced weight, blood profile, and abdominal fat loss. [Conclusion] Twenty weeks of high fat diet induced obesity, which was shown to inhibit normal mitochondria fusion and fission functions in hippocampal tissues. However, treadmill exercise was shown to have positive effects on these pathophysiological phenomena. Therefore, treadmill exercise should be considered during prevention and treatment of obesity-induced metabolic diseases.

한국형 산림토양탄소모델(KFSC)을 이용한 수확 주기 및 강도와 수확 후 잔재물 처리방법에 따른 소나무림 토양탄소 저장량의 장기 변화 추정 연구 (Estimation of Long-term Effects of Harvest Interval and Intensity, and Post-harvest Residue Management on the Soil Carbon Stock of Pinus densiflora Stands using KFSC Model)

  • 박찬우;이궁;이종열;이경학;이명종;김춘식;박관수;김래현;손요환
    • 한국산림과학회지
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    • 제102권1호
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    • pp.82-89
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    • 2013
  • 벌채 수확은 토양 내 탄소 동태를 변화시킬 수 있는 중요한 교란 중 하나이다. 그러나 수확에 따른 토양탄소 변화를 현지에서 장기간 연구하는 데에는 여러 가지 제한 요건이 있기 때문에 수학적 모델을 이용하여 장기적인 토양탄소 변화 경향을 효율적으로 추정할 수 있다. 본 연구에서는 최근 개발된 한국형 산림토양탄소 모델(KFSC 모델)을 이용하여 국내 중부지방 소나무(Pinus densiflora S. et Z.) 임분을 대상으로 수확의 주기, 강도, 수확 후 잔재물 처리방법에 따른 산림토양탄소 동태의 장기 변화를 모의하였다. 모의 시나리오는 3개의 수확 주기(50년, 80년, 100년), 2개의 수확 강도(재적 대비 30%의 부분수확 및 100%의 개벌수확), 2개의 수확 후 잔재물 처리방법(지상부 잔재물의 전량 수거 및 전량 방치) 등을 조합하여 총 12개로 이루어졌으며, 연간 토양탄소 저장량의 변화를 400년 간 모의하였다. 모의 결과, 400년 후 30 cm 깊이까지의 토양탄소 저장량은 시나리오별로 50.3-55.8 Mg C $ha^{-1}$(현재 토양탄소 저장량 대비: 98.1-108.9%)의 범위를 나타냈다. 수확 후 잔재물을 전량 방치할 경우 잔재물을 전량 수거할 때보다 토양탄소 저장량이 2.5-11.0% 증가하는 것으로 모의되었으나, 수확 주기 및 강도에 따른 토양탄소 저장량 변화에서는 일정한 경향이 나타나지 않았다. 토양탄소 저장량의 변화 경향은 고사유기물의 변화 경향과 일치하였으며, 고사유기물의 변화 경향은 수확 시 발생하는 고사유기물의 양과 수확 후 임분 생장 형태에 의해 달라지는 것으로 나타났다.

해충발생동태 및 예찰모델 개발: 수원에서의 이화명나방 발생 사례 (Development of Insect Population Dynamics and Forecast Models: A Case of Chilo suppressalis(Walker) Occurrence in Suwan)

  • 이준호
    • 한국응용곤충학회지
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    • 제38권3호
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    • pp.231-240
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    • 1999
  • 수원 지역에서의 이화명나방 발생의 장기적 경시적 변화 패턴을 분석하고 수원 지역에서의 이화명나방 봄나방(I화기) 발생시기 예찰 모델을 개발하였다.수원에서의 이화명나방의 개체군동태는 1965년부터 1996년까지 한 번의 큰 피크와 한 번의 작은 피크를 보인 주기적 변동을 보였으며 발생 변동의 큰 주기는 대략 36세대 (18년)로 분석되었다. 수원 지역에서의 이화명나방 발생동태는 l세대를 작은 주기로 하는 내적 유발성 주기성을 보였으며 전세대의 밀도의존성이 높은 제 l차 부의 피이드백 작용에 의해 지배되는 내적 동태성이 기본이었다. 이화명나방 개체군 변동 메카니즘은 밀도의 급격한 감소에도 불구하고 변화가 없었다.수원 지역의 이화명나방 발생 자료를 바탕으로 봄나방 발생시기 예찰 모델들(온도발육모델 및 온일도 모델)을 개발하였다.또한, 이화명나방 개체군 동태와 관련한 봄나방 성충 예찰 문제를 고찰하였다.

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Monitoring a steel building using GPS sensors

  • Casciati, Fabio;Fuggini, Clemente
    • Smart Structures and Systems
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    • 제7권5호
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    • pp.349-363
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    • 2011
  • To assess the performance of a structure requires the measurement of global and relative displacements at critical points across the structure. They should be obtained in real time and in all weather condition. A Global Navigation Satellite System (GNSS) could satisfy the last two requirements. The American Global Position System (GPS) provides long term acquisitions with sampling rates sufficient to track the displacement of long period structures. The accuracy is of the order of sub-centimetres. The steel building which hosts the authors' laboratory is the reference case-study within this paper. First a comparison of data collected by GPS sensor units with data recorded by tri-axial accelerometers is carried out when dynamic vibrations are induced in the structure by movements of the internal bridge-crane. The elaborations from the GPS position readings are then compared with the results obtained by a Finite Element (FE) numerical simulation. The purposes are: i) to realize a refinement of the structural parameters which characterize the building and ii) to outline a suitable way for processing GPS data toward structural monitoring.

LONG-TIME BEHAVIOR OF A FAMILY OF INCOMPRESSIBLE THREE-DIMENSIONAL LERAY-α-LIKE MODELS

  • Anh, Cung The;Thuy, Le Thi;Tinh, Le Tran
    • 대한수학회보
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    • 제58권5호
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    • pp.1109-1127
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    • 2021
  • We study the long-term dynamics for a family of incompressible three-dimensional Leray-α-like models that employ the spectral fractional Laplacian operators. This family of equations interpolates between incompressible hyperviscous Navier-Stokes equations and the Leray-α model when varying two nonnegative parameters 𝜃1 and 𝜃2. We prove the existence of a finite-dimensional global attractor for the continuous semigroup associated to these models. We also show that an operator which projects the weak solution of Leray-α-like models into a finite-dimensional space is determining if it annihilates the difference of two "nearby" weak solutions asymptotically, and if it satisfies an approximation inequality.

Dynamics of Exchangeable Magnesium of Soil in Long-term Fertilization Experiment

  • Kim, Myung-Sook;Park, Seong-Jin;Lee, Chang-Hoon;Yun, Sun-Gang;Ko, Byong-Gu
    • 한국토양비료학회지
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    • 제48권6호
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    • pp.641-647
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    • 2015
  • Monitoring of soil fertility by long-term application of fertilizers is necessary to improve the fertility of soil and the productivity of crop. The objective of this study was conducted to investigate the changes of exchangeable Mg by continuous application of fertilizers from 1969 to 2014. The treatments were no fertilization (No fert.) and fertilization (NPK, NPK+C, NPK+S, and NPK+CS). The concentration of exchangeable Mg in No fert., NPK+C, and NPK+S treatments tended to increase from 1965 to 1975, but decrease gradually from 1976 to 1987, and increase again after 1988. Based on these, the changes of exchangeable Mg were divided into period I ('69 ~'75), period II ('76~'87), and period III ('88~'14). Especially, exchangeable Mg decreased in the period II. This was presumed that a significant amount of Mg from topsoil were leached into subsoil by break of plow pan and some of subsoil was incorporated into topsoil according to change of plowing depth by replacement of tillage machinery. It could be possible that exchangeable Mg in NPK, NPK+S, and NPK+CS was accumulated in the depth of 15~20 cm. For the period III, exchangeable Mg in No fert., NPK, NPK+C, NPK+S, and NPK+CS treatments increased at rates of 0.013, 0.018, 0.015, 0.023, and $0.024cmolckg^{-1}{\cdot}yr^{-1}$ respectively. Exchangeable Mg level in NPK+S was lower than the other treatments in the period I and period II, but higher than in the period III. This result was attributed to replacement of silicate fertilizer type from wollastonite (Mg 0.3%) to silicate fertilizer (Mg 3%). Also, exchangeable Mg level of No fert. treatment increased, which showed that Mg concentration of irrigated water had the greatest impact on Mg accumulation of soil. Recently, Mg level of irrigated water tended to increase, indicating that Mg concentration of water will affect greatly the concentration of exchangeable Mg of soil in the future. Like these, the changes of exchangeable Mg were greatly influenced by agricultural environment such as plowing depth, plow pan, content of fertilizer, and quality of irrigated water. Considering these agricultural environment, the proper management of soil is needed for the improvement of soil fertility and crop productivity.

화학사고물질 노출에 따른 피해지역 주민 건강위해성평가: 폼알데하이드 사례를 중심으로 (Health Risk Assessment for Residents after Exposure to Chemical Accidents: Formaldehyde)

  • 박시현;조용성;임희빈;박지훈;이철민;황승율;이청수
    • 한국환경보건학회지
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    • 제47권2호
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    • pp.155-165
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    • 2021
  • Objectives: Acute exposure to high concentrations of chemicals can occur when a chemical accident takes place. As such exposure can cause ongoing environmental pollution, such as in the soil and groundwater, there is a need for a tool that can assess health effects in the long term. The purpose of this study was assessing the health risks of residents living near a chemical accident site due to long-term exposure while considering the temporal concentration changes of the toxic chemicals leaked during the accident until their extinction in the environment using a multimedia environmental dynamics model. Methods: A health risk assessment was conducted on three cases of formaldehyde chemical accidents. In this study, health risk assessment was performed using a multimedia environmental dynamics model that considers the behavior of the atmosphere, soil, and water. In addition, the extinction period of formaldehyde in the environment was regarded as extinction in the environment when the concentration in the air and soil fell below the background concentration prior to the accident. The subjects of health risk assessment were classified into four groups according to age: 0-9 years old, 10-18 years old, 19-64 years old, and over 65 years old. Carcinogenic risk assessment by respiratory exposure and non-carcinogenic risk assessment by soil intake were conducted as well. Results: In the assessment of carcinogenic risk due to respiratory exposure, the excess carcinogenic risk did not exceed 1.0×10-6 in all three chemical accidents, so there was no health effect due to the formaldehyde chemical accident. As a result of the evaluation of non-carcinogenic risk due to soil intake, none of the three chemical accidents had a risk index of 1, so there was no health effect. For all three chemical accidents, the excess cancer risk and hazard index were the highest in the age group 0-9. Next, 10-18 years old, 65 years old or older, and 19-64 years old showed the highest risk. Conclusion: This study considers environmental changes after a chemical accident occurs and until the substance disappears from the environment. It also conducts a health risk assessment by reflecting the characteristics of the long-term persistence and concentration change over time. It is thought that it is of significance as a health risk assessment study reflecting the exposure characteristics of the accident substance for an actual chemical accident.

Production of Fine-resolution Agrometeorological Data Using Climate Model

  • Ahn, Joong-Bae;Shim, Kyo-Moon;Lee, Deog-Bae;Kang, Su-Chul;Hur, Jina
    • 한국농림기상학회:학술대회논문집
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    • 한국농림기상학회 2011년도 학술발표회
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    • pp.20-27
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    • 2011
  • A system for fine-resolution long-range weather forecast is introduced in this study. The system is basically consisted of a global-scale coupled general circulation model (CGCM) and Weather Research and Forecast (WRF) regional model. The system makes use of a data assimilation method in order to reduce the initial shock or drift that occurs at the beginning of coupling due to imbalance between model dynamics and observed initial condition. The long-range predictions are produced in the system based on a non-linear ensemble method. At the same time, the model bias are eliminated by estimating the difference between hindcast model climate and observation. In this research, the predictability of the forecast system is studied, and it is illustrated that the system can be effectively used for the high resolution long-term weather prediction. Also, using the system, fine-resolution climatological data has been produced with high degree of accuracy. It is proved that the production of agrometeorological variables that are not intensively observed are also possible.

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Effects of Head-Up Tilt on Nonlinear Properties of Heart Rate Variability in Young and Elderly Subjects

  • Jin, Seung-Hyun;Kim, Wuon-Shik;No, Ki-Yong
    • International Journal of Vascular Biomedical Engineering
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    • 제3권1호
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    • pp.14-22
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    • 2005
  • In the present study, our aim is to investigate whether responses to the head-up tilt (HUT) on nonlinear properties of heart rate variability (HRV) in young and elderly subjects are different or not. Thirteen young-healthy subjects ($24.5{\pm}3.7$ years) and 18 old-aged healthy subjects ($74.5{\pm}7.4$ years) participated in this study. An electrocardiogram (ECG) in the supine posture, at $0^{\circ}$, and in the standing posture, at $70^{\circ}$ of head-up tilt, was recorded. Detrended fluctuation analysis (DFA) and approximate entropy (ApEn), measures of short-/long-term correlation properties and overall complexity of heart rate (HR) respectively, along with spectral components of HR variability (HRV) were analyzed for both the supine and HUT postures. We observed that the short-term fractal exponent ${\alpha}_1$ increased during HUT posture (F(1, 29) = 39.79, P = 0.000), especially, the young subjects showed a significantly higher values compared to the elderly subjects. ApEn significantly decreased (F(1, 29) = 8.61, P = 0.006) during HUT posture. HUT posture decreased the complexity in HR dynamics and increased short-term fractal exponent values in young subjects but not in elderly subjects. These results imply that there are differences of response to HUT on nonlinear properties between young and elderly subjects.

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한국경제(韓國經濟)의 다부문모형(多部門模型) : 모형구조(模型構造)와 추정결과(推定結果) (The Multisector Model of the Korean Economy: Structure and Coefficients)

  • 박준경;김정호
    • KDI Journal of Economic Policy
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    • 제12권4호
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    • pp.3-20
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    • 1990
  • 다부문모형(多部門模型)은 산업련관자료(産業聯關資料)를 비롯한 산업정보자료(産業情報資料)를 이용하여 장기의 구조변화를 분석 전망하고 총생산성(總生産性)과 요소가격(要素價格)의 변동에 의한 산업경쟁력(産業競爭力)의 추이를 분석하여 중기의 성장전망(成長展望)을 시산(試算)하는 연간(年間) 계량모형(計量模型)으로 25개 산업부문(産業部門)의 1,300여개(餘個)의 구조식(構造式) 정의식(定義式)으로 구성된다. 국내가격과 국제가격(國際價格)의 차이가 산업 무역구조에 영향을 미치고 국내생산과 요소가격이 산업별 요소수요(要素需要)를 결정하며 요소수요와 요소가격에 의하여 소득(所得)이 결정되고 소득과 가격이 산업별 소비지출(消費支出)을 결정한다 ; 산업별 총생산성과 상대가격(相對價格)이 투입산출계수(投入産出係數)에 영향을 미치고 투입산출계수와 상대가격이 산업별 생산비용(生産費用)을 결정하며 생산비용과 경쟁수입가격(競爭輸入價格)을 고려하여 국내가격이 결정된다 ; 생산성증가(生産性增加)와 임금상승(賃金上昇)의 산업간(産業間) 차이가 상대가격(相對價格)을 변화시키고 이로 인하여 산업(産業) 무역(貿易) 고용구조(雇傭構造)가 선진국(先進國)과 동질화(同質化)되는 지식(知識) 기술집약화(技術集約化) 과정이 전개된다.

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