• Title/Summary/Keyword: Long-term Preservation

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Long-Term Results of Surgical Treatment for Sacral Chordoma (천추 척색종의 수술적 치료 후 장기 추시 결과)

  • Chung, Jae-Yoon;Lee, Jae-Joon;Seo, Hyoung-Yeon;Jung, Sung-Taek
    • The Journal of the Korean bone and joint tumor society
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    • v.11 no.2
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    • pp.148-154
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    • 2005
  • Purpose: To evaluate the long term results of surgical treatment for sacral chordoma. Material and Method: We reviewed the records of 4 patients with sacral tumor treated surgical resection. Mean follow-up duration was 8.3 year(3~11). All cases were performed complete resection of tumor mass through posterior approach in 3 cases and anterior-posterior approach in one. The most caudad nerve-roots spared were the second sacral roots in one and the third sacral roots in 3 cases. Functions of voiding and defecation including neurological symptoms of lower extremities, other complications of surgical treatment, and local recurrence or distant metastasis of tumor were evaluated. Result: There was no motor deficit in all cases, but radiating pain was developed in one and wound infection in one. Bladder function was preserved in 2 cases, intermittent incontinence in one, and doing intermittent catheterization in one. Bowel function was preserved in one and 2 cases were suffered from constipation. At the last follow-up, disease-free was in one, local recurrence in one, and local recurrence with distant metastasis in one. Conclusion: The result of surgical resection for sacral chordoma is satisfactory showing average 8 years survival. Early detection and aggressive surgical treatment is the best to prolong survival and to minimize functional deficit with preservation of upper sacral nerves.

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Application of Artificial Neural Network Ensemble Model Considering Long-term Climate Variability: Case Study of Dam Inflow Forecasting in Han-River Basin (장기 기후 변동성을 고려한 인공신경망 앙상블 모형 적용: 한강 유역 댐 유입량 예측을 중심으로)

  • Kim, Taereem;Joo, Kyungwon;Cho, Wanhee;Heo, Jun-Haeng
    • Journal of Wetlands Research
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    • v.21 no.spc
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    • pp.61-68
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    • 2019
  • Recently, climate indices represented by quantifying atmospheric-ocean circulation patterns have been widely used to predict hydrologic variables for considering long-term climate variability. Hydrologic forecasting models based on artificial neural networks have been developed to provide accurate and stable forecasting performance. Forecasts of hydrologic variables considering climate variability can be effectively used for long-term management of water resources and environmental preservation. Therefore, identifying significant indicators for hydrologic variables and applying forecasting models still remains as a challenge. In this study, we selected representative climate indices that have significant relationships with dam inflow time series in the Han-River basin, South Korea for applying the dam inflow forecasting model. For this purpose, the ensemble empirical mode decomposition(EEMD) method was used to identify a significance between dam inflow and climate indices and an artificial neural network(ANN) ensemble model was applied to overcome the limitation of a single ANN model. As a result, the forecasting performances showed that the mean correlation coefficient of the five dams in the training period is 0.88, and the test period is 0.68. It can be expected to come out various applications using the relationship between hydrologic variables and climate variability in South Korea.

A Study on the Development Direction of Specialized Library in Road Traffic Field (도로교통분야 전문도서관 발전방향 모색에 관한 연구)

  • Kwak, Seung-Jin;Noh, Younghee;Chang, Inho;Ko, Jae Min
    • Journal of Korean Library and Information Science Society
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    • v.53 no.2
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    • pp.73-94
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    • 2022
  • This study is a basic research for establishing a mid- to long-term development plan for the library of the Korea Expressway Corporation that can establish the vision and core values of the library and continuously grow by taking advantage of the specialization of the road transportation field in preparation for the 4th industrial revolution and post-corona era. The current state, satisfaction, and demand of the library were conducted for users of the Korea Expressway Corporation, and based on this, a mid- to long-term development plan was proposed. As a result of the research, first, the library of the Korea Expressway Corporation should provide information services to respond to the immediate information needs of its members as a library that supports academic and research activities as well as the comprehensive collection and preservation of related materials as a national road transportation representative library. Second, it is necessary to establish a systematic collection development policy, and it is necessary to collect collections by detailed themes related to road traffic. Third, overall service development is necessary, and Korea Expressway Corporation library homepage and mobile service should be developed. Lastly, space improvement must be made through space reorganization, and it is necessary to expand the usability through the introduction of the latest technology.

Long Term Results of Radiation Therapy in Early Glottic Cancer (초기 성문암의 방사선치료: 장기 추적결과)

  • Kim, Jin-Hee;Byun, Sang-Jun
    • Radiation Oncology Journal
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    • v.27 no.1
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    • pp.29-34
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    • 2009
  • Purpose: This study was designed to evaluate long-term results in terms of failure, survival and voice preservation after radiation therapy for early glottic cancer. Materials and Methods: From February 1988 to December 2003, 70 patients with early glottic cancer were treated with radiation therapy at Keimyung University Dongsan Medical Center. Patient age distribution was from 39 to 79 years, with a median age of 62 years. All patients had squamous cell carcinoma. According to the TNM stage, 58 patients had stage I disease, 12 patients had stage II disease; 67 patients were male. The laryngeal area was irradiated with the use of bilateral opposing fields with/without a wedge filter with 6 MV photons at a total dose of $54{\sim}70.2$ Gy in $1.8{\sim}2.2$ Gy fractions over $6{\sim}8$ weeks. We delivered a median radiation dose of 60 Gy for stage I patients and a median radiation dose of 66 Gy for stage II patients. Salvage surgery was performed in patients with local recurrence. The voice preservation rate was analyzed after all treatments including salvage surgery. Follow-up periods were from 13 to 180 months, with a median follow-up period of 77.5 months. The survival rate was analyzed by the use of the Kaplan Meier method and log rank test. A comparison of two groups was performed with the use of the chi-squared test. Results: The local control rate was 98.5% (69/70). The five-year-overall survival rate was 93.9%. The five-year disease free survival rate (5YDFS) was 84.1% and the 5YDFS after radiation and salvage surgery was 92.8%. According to stage, the 5YDFS was 93.1% and 91.7% for stage I and stage II respectively. Thirteen patients (18.5%) had local failure with 24 months of median time to local failure and nine patients received salvage surgery; however, four patients were lost to follow-up after a diagnosis of recurrence. Only two patients died due to a distant metastasis at 33 months and 71 months after radiation therapy, respectively. Nine patients died due to other diseases with a median time of 73 months. There were no severe acute or chronic complications after radiation therapy. Voice preservation was ultimately achieved in 88.5% (62/70) of patients. Conclusion: We considered that radiation therapy was effective and we achieved excellent survival and voice preservation in early laryngeal cancer. The use of radiation therapy should be the first choice for the treatment of early glottic cancer.

Population Genetic Structure of the Bumblebee, Bombus ignitus (Hymenoptera: Apidae), Based on Mitochondrial COI Gene and Nuclear Ribosomal ITS2 Sequences

  • Oh, Hyung Keun;Yoon, Hyung Joo;Lee, Joo Young;Park, Jeong Sun;Kim, Iksoo
    • International Journal of Industrial Entomology and Biomaterials
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    • v.27 no.1
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    • pp.142-158
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    • 2013
  • The bumblebee, Bombus ignitus (Hymenoptera: Apidae), is a valuable natural resource that is widely utilized for greenhouse pollination in South Korea. Understanding the magnitude of genetic diversity and geographic relationships is of fundamental importance for long term preservation and utilization. As a first step, we sequenced a partial COI gene of mitochondrial DNA (mtDNA) corresponding to the "DNA barcode" region and the complete internal transcribed spacer 2 (ITS2) of nuclear ribosomal DNA from 88 individuals collected in nine South Korean localities. The complete ITS2 sequences were longest among known insects, ranging in size from 2,034 bp ~ 2,052 bp, harboring two duplicated 112-bp long repeats. The 658-bp long mtDNA sequences provided only six haplotypes with a maximum sequence divergence of 0.61% (4 bp), whereas the ITS sequences provided 84 sequence types with a maximum sequence divergence of 1.02% (21 sites). The combination of the current COI data with those of published data suggest that the B. ignitus in South Korea and China are genetically a large group, but those in Japan can be roughly separated into another group. Overall, a very high per generation migration ratio, a very low level of genetic fixation, and no discernable hierarchical population were found to exist among the South Korean populations of B. ignitus, which suggests panmixia. This finding is consistent with our understanding of the dispersal capability of the species.

Gamma Knife Radiosurgery for Vestibular Schwannomas

  • Lim, Young-Jin;Choi, Seok-Keun
    • Journal of Korean Neurosurgical Society
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    • v.42 no.3
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    • pp.159-167
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    • 2007
  • Vestibular schwannoma (VS) is a benign tumor typically originated in the schwann cell of vestibular nerve and usually accompany hearing symptom. Microsurgical removal and radiosurgery have a great role for the treatment of VS. Recently radiosurgery has been considered as an alternative or primary treatment for VS with the tremendous increase of patients who were treated with gamma knife radiosurgery (GKS) though microsurgery still takes the premier. By many published results, it is proved that GKS is a effective and noninvasive technique for VS, especially small sized tumors with satisfactory tumor control rate. The authors assumed that GKS can be expected to achieve satisfactory tumor control rate for small VS under 5cc in volume. A major interest regarding radiosurgery nowadays is to determine the optimal radiation dose for hearing preservation to improve the quality of life of patients. The more high radiation dose are used for effective tumor growth control, the more radiation-related complications like as hearing deficit, the impairment of other cranial nerve function are increased. Since 1990's the mean radiation dose for tumor margin was more than 18 Gy, but there were high complication rate in spite of good tumor growth control. After the year of 2000, under the influence of advanced neuro-imaging techniques and radiosurgical planning system which enable clinicians to do more precise planning, marginal dose for VS has been decreased to 12-13 Gy and the radiation-related complications has been reduced. But because there may be a unexpected radiation induced complications as time goes by after the latency period, optimal radiation dose for VS should be established on the basis of more long term follow-up observation.

Effect of Storage Temperature and Humidity on the Quality Stability of Chestnuts (밤의 품질안정성에 대한 저장 온.습도 조건의 영향)

  • Gwon, Jung-Ho;Choe, Jong-Uk;Byeon, Myeong-U
    • Food Science and Preservation
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    • v.5 no.1
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    • pp.7-12
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    • 1998
  • Chestnuts(Castanea cretana, Eunki) were used for quality evaluations from the physiological and physicochemical points of view during storage under different temperatures and relative humidities for 8 months. Quality criteria included spouting, rotting, weight loss, and the changes in moisture, total sugar, reducing sugar, and total vitamin C of the stored sample. Sprouts(roots) were developed in about 2 months in all stored samples which had been mixed with sawdust(50% moisture) and stored under the conditions of 2∼25$^{\circ}C$ and 62∼95% RH. The sprout development was more significant in the storage temperature of Pit(9${\pm}$6$^{\circ}C$, 80${\pm}$5% RH, PT)and room(16${\pm}$7$^{\circ}C$, 85${\pm}$10% RH, RT) than low(3${\pm}$1%, 80${\pm}$5% RH, LT)and ambient(14${\pm}$11$^{\circ}C$, 67${\pm}$5% RH, AT). The rates of rotting and weight loss were appreciable in the order of PT, AT, RT and LT, and those of LT were 1∼2%. The use of wet sawdusts resulted in the increase of moisture contents in stored samples, thereby causing the rotting phenomena. Some chemical components of stored samples were found liable to the changes according to storage conditions, that is; total sugars showed a decreasing tendency along with a temporary increase during storage, and both reducing sugar and vitamin C were similarly accumulated in the samples stored at low temperature conditions. The results indicated that long-term storage of chestnuts will be possible in either cases of the application of low temperature following sprout-inhibition treatment or the use of lower temperature than 0$^{\circ}C$ to suppress its sprouting during storage.

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Development of the Corrugated fiberboard Box for Cold-chain Distribution of Chinese Cabbage (배추의 저온유통용 골판지포장상자 개발)

  • Lee, Won-Og;Yun, Hong-Sun;Jeong, Hoon;Lee, Hyun-dong;Cho, Kwang-Hwan;Kim, Man-Soo
    • Food Science and Preservation
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    • v.10 no.1
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    • pp.23-27
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    • 2003
  • This study was conducted to develop the corrugated fiberboard box which is suitable to pre-cooling and low temperature distribution of chinese cabbage Consider from a cooling performance viewpoint, the folding type box with 5.4% vent hole ratio was most efficient for fast cooling and even temperature distribution in the packaging box. At the end of storage periods, the compressive strength of the folding type box was less than the bliss type box. However, the compressive strength of the folding type box after storage was higher than required safety compressive strength for long term storage. So the folding type box was considered to have no problems toy practical use. The shelf-life of the chinese cabbage packaged with the developed box was 6∼7 days which was 2∼3 days longer than usual packaging.

Risk Assessment of Aldehydes and Volatile Organic Compounds in the National Library of Korea Archive (국립중앙도서관 귀중서고 내 알데히드류 및 휘발성유기화합물(VOCs)에 대한 건강위해성평가)

  • Lee, Hye-Won;Lim, Hui Been;Lee, Kwi-Bok;Park, So Yeon;Jeon, Jeong In;Lee, Cheol Min
    • Journal of Environmental Science International
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    • v.29 no.6
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    • pp.673-682
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    • 2020
  • This study investigates the concentration distribution of aldehydes and volatile organic compounds (VOCs) in the archive of the National Library in Korea and evaluates the health risks to workers from hazardous chemicals. Acetaldehyde had the highest concentration among the nine species of aldehydes present in the archive and the concentration of toluene was the highest among the six species of VOCs. Most of the detected substances showed that their indoor concentrations were higher than the outdoor ones, suggesting the possibility of indoor sources of aldehydes and VOCs. The evaluation of health risks for workers based on these measurement results showed that not all substances were hazardous to the human body. However, considering the possibility of the presence of indoor sources and the potential limits of our study owing its short period, it is necessary to conduct long-term studies on the concentration distribution of indoor pollutants in the archive environment.

Influence of porosity and cement grade on concrete mechanical properties

  • Huang, Jiandong;Alyousef, Rayed;Suhatril, Meldi;Baharom, Shahrizan;Alabduljabbar, Hisham;Alaskar, Abdulaziz;Assilzadeh, Hamid
    • Advances in concrete construction
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    • v.10 no.5
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    • pp.393-402
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    • 2020
  • The given research focuses on examining the effect of relatively humidity (RH) and curing temperature on the hydrates as well as the porosity of calcium sulfoaluminate (CSA) cement pastes. Numerous tests, which consist of mercury intrusion porosimetry (MIP), thermosgravi metric (TG) and X-ray diffraction (XRD) were conducted. Various characterization techniques which include, scanning electron microscopy, Fourier transform microscopy along with X-ray diffraction evaluations were conducted on the samples to examine phase formation and crystallinity, morphology and microstructure along with bond formations and functional groups, respectively. During long-term study, the performance of concrete which consisted of limestone and flash-calcined was close to those from standard Portland cement concrete. Traditional classifications and methods of corrosion were widely used for the assessment of steel in concrete which may get employed to concrete which contains LC3 to recalibrate the range of polarization resistance for passitivity condition. For example, there is up to 79.5% and 146% respective flexural and compressive strengths. Moreover, they developed more advance electrical and thermo-mechanical performance with a substantial reduction in absorption of water of close to 400%. These advantages allow this research crucial to evaluate how these methods can be applied. Additionally, the research evaluates developed and more advanced cement preservation and repair techniques. The conclusion suggests concerted efforts by various stakeholders such as policy makers to enable low-carbon rates.