• 한국약용작물학회지
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• 제14권6호
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• pp.329-335
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• 2006

The present study was designed to investigate aging-related effects on the activities of xenobiotic metabolizing enzymes of rat liver by dietary supplementation of Korean red ginseng water-extract. Rat did not show any discernible signs of the rejection symptoms, and blood GOT and GPT levels were not influenced by ginseng water extracts, Cytochrome 450 levels and NADPH cytochrome P45O reductase, p-450 dependent ethoxycoumarin O-deethylase, and benzphetamine N-demethylase activities were decreased with aging, however, these phase I system enzymes activities in the ginseng group of24 months were well maintained compared with normal group. But, Levels of cytochrome bs and NADH-cytochrome b$_5$ reductase activities were also decreased with aging and were not found a clear difference between two groups. Glutathione-s-transferase activity, phase II enzyme system, in liver cytosols was also decreased in old ages, but the degree of decrease was higher in normal group than in giuseng supplemented group. These results indicate that long-term supplementation of red ginseng water extracts from weaning to 24 months do not show any side effects to rats, and retard age-related deteriorations of xenobiotic metabolizing enzymes activities in old ages.

• 조명전기설비학회논문지
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• 제20권10호
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• pp.141-150
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• 2006

본 논문에서는 폴리머피뢰기의 현장 열화인자를 인가할 수 있는 가속열화 시험장치를 제작하고 국내 환경조건을 모의할 수 있는 시험주기를 개발하여 폴리머피뢰기 완제품에 대한 장기신뢰성 평가법을 제안하였다. 그리고 가속열화시험 및 현장설치에 의한 전기적, 화학적 특성변화를 분석하여 폴리머피뢰기의 열화정도를 평가함으로써 본 연구에서 제안한 평가기법의 실효성을 검증하고 국산 폴리머피뢰기의 유지보수에 필요한 특성 데이터를 제시하였다.

• Carbon letters
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• 제28권
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• pp.9-15
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• 2018

In the aerospace field, Carbon/Cork composites have been used for rocket propulsion systems as a light weight structural component with a high bending stiffness and high thermal insulation properties. For the fabrication of a carbon composite with a heat insulation cork part, the bonding properties between them are very important to determine the service life of the Carbon/Cork composite structure. In this study, the changes in the interfacial adhesion and mechanical properties of Carbon/Cork composites under accelerated aging conditions were investigated. The accelerated aging experiments were performed with different temperatures and humidity conditions. The properties of the aged Carbon/Cork composites were evaluated mainly with the interfacial strength. Finally, the lifetime prediction of the Carbon/Cork composites was performed with the long-term property data under accelerated conditions.

• 대한기계학회논문집A
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• 제29권9호
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• pp.1253-1261
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• 2005

Cast stainless steel (CSS) is thermally aged by a long term exposure in the range of nuclear power plant operating temperature. The thermal aging is a cause of concern for the continued safe and reliable operation of CSS nuclear components. Therefore, an assessment of degradation in material properties of these components has been importantly considered. In this study the ball indentation tests were performed on four cast stainless steels aged at $400^{\circ}C$ for 3600 hours, to investigate the applicability of ball indentation test to the assessment of aging degradation of cast stainless steels. Thus, the reliability of ball indentation test for aged CSS was analyzed by evaluating the scattering of data tested from each material and by comparing tensile properties obtained from ball indentation test and standard tensile test. Also, the tensile properties of aged CSS obtained from ball indentation test were compared with those predicted by the evaluation procedure developed on the basis of material database for aged CSS.

• 펄프종이기술
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• 제46권5호
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• pp.35-42
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• 2014

Many historical archives have been deteriorated by aging with time. Various kinds of defects such as worm-hole, yellowing, brittleness are observed and their severity was dependent on raw material type, storage condition, and so on. For a long-term use and storage, a proper preservation treatment is required. Many studies on preservation and conservation have been carried out on hanji which was made from mulberry fiber, but there are few concerns on foreign paper. Therefore, aging and chemical strengthening treatment was done on paper made of bamboo and wood fibers depending on aging condition, the type and pickup weight of chemicals and treatment method. When methyl cellulose was treated with impregnation or brushing, the aged paper was strengthened effectively. The strengthening effect by chemicals was dependent on the aged condition of the paper.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2008년도 춘계학술대회 논문집
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• pp.224-231
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• 2008

A subway or an underground railway is one of the representative public transportations which lots of people take everyday. Then, subway station, which is also one of the very important public civil infrastructures, generally services for a long period of time. During the service time of stations, they are easily damaged from environmental corrosion, material aging, fatigue, and the coupling effects with long-term loads and extreme loads. Recently, civil construction work on the places near station often creates lots of damages to the station. As these damages accumulate, the performance of station degenerates due to the above factors. They would inevitably reduce the resisting capacity of station against the disaster; even they bring into the collapse of stations with the structural failure under long-term loads and extreme loads. And, if disaster such as earthquake, fire, etc. happens, it causes huge property damage and threatens the human lives. Because of these above reasons, the structural health monitoring system need to be developed for ensuring the safety of station. In this paper, the development directions of the structural health monitoring system with fiber optic sensor and USN for subway station are briefly described.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 추계학술대회 논문집 전기기기 및 에너지변환시스템부문
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• pp.157-159
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• 2002

In order to obtain reliability and extend life of GAS Voltage Transformer in GIS, it has to prevent aging by overvoltage considered to insulation characteristics of insulating material. This paper describes some characteristics of V-T characteristics and partial discharges.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1997년도 하계학술대회 논문집 C
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• pp.1408-1410
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• 1997

Arrhenius plots are useful in predicting long-term use temperatures of organic materials and in choosing parameters for accelerated aging. The effects of antioxidant on the heat resistance and temperature index of EPDM rubber used for electrical insulation were investigated. The short-time points were obtained by 50% retention of elongation at break.

• Nutrition Research and Practice
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• 제16권5호
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• pp.549-564
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• 2022

BACKGROUND/OBJECTIVES: Oxidative stress is caused by an imbalance between harmful free radicals and antioxidants. Long-term oxidative stress can lead to an "exhausted" status of antioxidant defense system triggering development of metabolic syndrome and chronic inflammation. Green perilla (Perilla frutescens) is commonly used in Asian cuisines and traditional medicine in southeast Asia. Green perilla possesses numerous beneficial effects including anti-inflammatory and antioxidant functions. To investigate the potentials of green perilla leaf extract (PE) on oxidative stress, we induced oxidative stress by high-fat diet (HFD) in aging mice. MATERIALS/METHODS: C57BL/6J male mice were fed HFD continuously for 53 weeks. Then, mice were divided into three groups for 12 weeks: a normal diet fed reference group (NDcon), high-fat diet fed group (HDcon), and high-fat diet PE treated group (HDPE, 400 mg/kg of body weight). Biochemical analyses of serum and liver tissues were performed to assess metabolic and inflammatory damage and oxidative status. Hepatic gene expression of oxidative stress and inflammation related enzymes were evaluated by quantitative real-time polymerase chain reaction (qRT-PCR). RESULTS: PE improved hepatopathology. PE also improved the lipid profiles and antioxidant enzymes, including hepatic glutathione peroxidase (GPx) and superoxide dismutase (SOD) and catalase (CAT) in serum and liver. Hepatic gene expressions of antioxidant and anti-inflammatory related enzymes, such as SOD-1, CAT, interleukin 4 (IL-4) and nuclear factor erythroid 2-related factor (Nrf2) were significantly enhanced by PE. PE also reduced the levels of hydrogen peroxide (H₂O₂) and malondialdehyde (MDA) in the serum and liver; moreover, PE suppressed hepatic gene expression involved in pro-inflammatory response; Cyclooxygenase-2 (COX-2), nitric oxide synthase (NOS), interleukin 1 beta (IL-1β), and interleukin 6 (IL-6). CONCLUSIONS: This research opens opportunities for further investigations of PE as a functional food and possible anti-aging agent due to its attenuative effects against oxidative stress, resulting from HFD and aging in the future.

• 한국건강관리협회지
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• 제2권3호
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• pp.31-46
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• 2004

Owing to continuous economic growth, an increased standard of living, and improvements to health care in Korea, the life expectancy of Koreans rose from 69.0years in 1985 to 71.3 years in 1990 It continued to rise throughout the 1990s, and, by2002, had reached 76.5 years for the general population and 80.0 years for Korean females. Similarly, the percentage of the Korean population that is 65 years of age or older Increased from 3.1 In 1970 to 7.1 In 2000, and is expected to reach approximately14.0 in 2019. Thus, according to this estimate, Korea will have evolved from an 'aging society 'to an "aged society" in only 19 years. In the case of other countries, this same transformation has generally taken 2 to 5 times longer. One of the major issues related to Korea's rapid1y aging population relates to the health problems of the elderly According to the 2002 National Health Survey Report,87.6 percent of the elderly were reported to have at least one chronic disease. In other words, almost 9 out of evert 10 elderly persons in Korea were suffering from a chronic illness. This, clearly, places a significant economic burden on Korean society in the form of increased health care costs. This paper examines the increasing prevalence of chronic diseases within Korea's rapidly aging population and offers some possible short- and long-term solutions to cope with the increased burden being placed on Korea's health care system. These Include the basic services at local health centers for the elderly and the national life-long health promotion programs that aim to correct unhealthy behavior, such as smoking, the excessive use of alcohol, and poor eating and exercise habits.