• Title/Summary/Keyword: Long Life Test

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The influence of various medicines and nutritional supplements against bacteria with gastrointestinal relevance (다양한 약물과 영양제가 장내세균에 미치는 영향)

  • Park, Jae Eun;Lee, Do Kyung;Ha, Nam Joo;Song, Young Cheon
    • Korean Journal of Microbiology
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    • v.51 no.1
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    • pp.61-67
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    • 2015
  • Recently, change of Western pattern diet and lifestyle is caused by various metabolic disorders and chronic diseases. These diseases need to take medicine regularly. Also, many people take health functional food, various vitamins and nutritional supplements in order to maintain a healthy life. But, there was no study about affects taking medicines against bacteria with gastrointestinal relevance. This study was performed by antibacterial activity test to evaluate the influence of a long time or commonly used medication. As a result, medicines of Vitamins & Minerals or Central nervous system show antibacterial activity against beneficial enteric bacteria and harmful enteric bacteria. Dexibuprofen of the Anti-inflammatory Drugs that acts on the central nervous system has shown high antibacterial activity at beneficial enteric bacteria strains (Lactobacillus casei, Lactobacillus rhamnosus) and harmful enteric bacteria (Staphylococcus aureus). Also, fenofibric acid of the antilipemic agents that acts on the Cardiovascular & Hematopoietic system has shown high antibacterial activity at beneficial enteric bacteria strains (Lactobacillus casei). Vitamins & Minerals appeared antibacterial activity against most intestinal bacteria. Vitamin B-Complex/with C and vitamin C were especially high with beneficial enteric bacteria strains (Bifidobacterium infantis) and harmful enteric bacteria (E. coli, E. aerogenes, S. flexneri, S. Typhimurium, S. aureus). Therefore, these results indicate that variously taking medicines have generally antibacterial activity against harmful enteric bacteria strains and beneficial enteric bacteria strains.

Intrathecal Block with 10% Phenol-Glycerine for Cancer Pain (암성통증(癌性痛症)에 대(對)한 지주막하(蜘蛛膜下) 10% Phenol-Glycerine 차단(遮斷))

  • Oh, Hung-Kun;Lee, Youn-Woo;Yoon, Duck-Mi;Paik, Sang-Ki;Bang, Sou-Ouk;Koh, Shin-Ock
    • The Korean Journal of Pain
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    • v.1 no.1
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    • pp.47-52
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    • 1988
  • Since 1979 forty-three cancer patients have been given intrathecal block at the pain clinic of Yonsei Medical Center. The male patients numbered 23 and female 20 and most of them were in the 4th and 5th decades of age. In 78.6% of the patients, the diagnosis was rectal cancer in 20 cases, cervix cancer in 7 cases, bladder cancer in 4 cases and colon cancer in 3 cases. Thirty six patients with cancer pain were treated by intrathecal 10% phenol-glycerine block and rest of them had only test block. Fourteen patients whose pain sites were lumbar or lumbar and upper sacral dermatomes were put into the lateral recumbent position on the fluoroscopic table. The spinal puncture was performed as close to the spinal roots to be impregnated as possible. In 22 patients the pain sites were covered by the sacral dermatomes and so the L5-S1 interspace was punctured in the sitting position shifted 15 degree to the affected site. Fifty one blocks were performed and their results are classified into three categories: good, fair antral poor. We achieved good results in 38 patients(77.1%), fair in 6 patients(17.1%) and poor in 2 patient(5.7%). Thus a satisfactory pain relief was achieved in 94.2% of patients. After intrathecal block with phenol glycerine, transient voiding difficulty was noted in 7, defecation difficulty in 1, and transient paresthesia and/or muscle weakness was present in 3 patients. The mean duration of pain relief was 2.5 months and longer than the mean survival time of 2.25 months. When patients are selected carefully and tile block is performed with great caution and good technique, the risk is minimal and a long lasting relief of intractable cancer pain achieves a painless life until death.

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Dissolution Profile Analysis of Hydroxypropyl Methylcellulose-based Vitamin C Tablets (Hydroxypropyl methylcellulose를 활용한 비타민 C 지속성 정제의 용출 특성 분석)

  • Cha, Ja-Hyun;Hong, Jun-Kee;Lee, Sung-Wan;Cha, Jae-Uk;Ko, Won-Hwa;Baek, Hyon-Ho;Park, Hyun-Jin
    • Korean Journal of Food Science and Technology
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    • v.44 no.3
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    • pp.274-279
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    • 2012
  • The objective of this study was to develop oral matrix tablets for the sustained release of vitamin C. In this study hydroxypropyl methylcellulose (HPMC) has been utilized as an excipient, as it is one of the most widely used polymers, for use during long periods of time in formations. The vitamin C tablet formulation depends on the molecular weight and concentration of sustained-delivery in HPMC. Anti-oxidants have been added as a dissolution medium in order to prevent vitamin C degradation in water. The dissolution test was carried out in a distilled water medium, and the release model equation was applied to analyze the vitamin C release pattern. The results demonstrated that the release and lasting power of vitamin C tablets, containing HPMC, lasted for more than 12 h.

Performance Based Evaluation of Concrete Strength and Freeze-Thaw Resistance from Wind Speed - Sunlight Exposure Time Effect (풍속과 일조시간에 따른 콘크리트의 강도 및 동결융해 저항성 성능중심평가)

  • Kim, Tae-Kyun;Choi, Seung-Jai;Choi, Ji-Hun;Kim, Jang-Ho Jay
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.21 no.1
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    • pp.49-58
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    • 2017
  • The phenomena that we experience in everyday life such as snow, rain, wind, and temperature are referred to as weather, and the average state of atmospheric phenomena that occur over a long period of time in a specific region is referred to as climate. In addition, significant variation of climate compared to the average state is referred to as climate change. Concrete structures can have various problems when exposed to elements. Among the problems, the freeze-thaw problem due to extreme climatic factors such as heavy rain and snowfall has become a particularly significant issue recently. The concrete that has been subjected to repeated freeze-thaw rather than too high or low temperature shows serious degradation of durability, and the performance of structures with degraded performance is difficult to recover. Therefore, in this study, concrete durability performance with respect to freeze-thaw from curing conditions change due to wind speed and sunshine exposure time. Concrete freeze-thaw experiment are performed. using wind speed and sunlight exposure time. Also, performance based evaluation through the satisfaction curve based on the freeze-thaw test results are performed.

Analysis of Paddy Rice Water Footprint under Climate Change Using AquaCrop (AquaCrop을 이용한 기후변화에 따른 미래 논벼 물발자국 변화 분석)

  • Oh, Bu-Yeong;Lee, Sang-Hyun;Choi, Jin-Yong
    • Journal of The Korean Society of Agricultural Engineers
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    • v.59 no.1
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    • pp.45-55
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    • 2017
  • Climate change causes changes in rainfall patterns, temperature and drought frequency. Climate change impact influences on water management and crop production. It is critical issue in agricultural industry. Rice is a staple cereal crop in South Korea and Korea uses a ponding system for its paddy fields which requires a significant amount of water. In addition, water supply has inter-relationship with crop production which indicates water productivity. Therefore, it is important to assess overall impacts of climate change on water resource and crop production. A water footprint concept is an indicator which shows relationship between water use and crop yield. In addition, it generally composed of three components depending on water resources: green, blue, grey water. This study analyzed the change trend of water footprint of paddy rice under the climate change. The downscaled climate data from HadGEM3-RA based on RCP 8.5 scenario was applied as future periods (2020s, 2050s, 2080s), and historical climate data was set to base line (1990s). Depending on agro-climatic zones, Suwon and Jeonju were selected for study area. A yield of paddy rice was simulated by using FAO-AquaCrop 5.0, which is a water-driven crop model. Model was calibrated by adjusting parameters and was validated by Mann-Whitney U test statistically. The means of water footprint were projected increase by 55 % (2020s), 51 % (2050s) and 48 % (2080s), respectively, from the baseline value of $767m^2/ton$ in Suwon. In case of Jeonju, total water footprint was projected to increase by 46 % (2020s), 45 % (2050s), 12 % (2080s), respectively, from the baseline value of $765m^2/ton$. The results are expected to be useful for paddy water management and operation of water supply system and apply in establishing long-term policies for agricultural water resources.

Development of Business Process Model for Overseas Natural Gas Pipeline Project at the Project Planning Phase (해외 천연가스 파이프라인 사업 진출을 위한 사업계획단계 의사결정 프로세스 모델 구축)

  • Sin, Eonill;Han, Seung-Heon;Jang, Woosik;Lee, Yong-Wook
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.32 no.5D
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    • pp.473-481
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    • 2012
  • Demand of Natural Gas (NG) consumption is continuously increasing by long service life and low environmental impact than other fossil fuels. Because of this reasons, Gas wells exploration and huge LNG plant construction project are being boosted world-widely. Especially, overseas NG pipe-line projects are emerging by considering safe and efficiency at the inter-country sections. At the same time, Korean contractors are being achieved to record-breaking performance at 2011's overseas construction market and 80% of new-record was attained from overseas plant construction projects. Nevertheless, Korean contractors are behind than overseas leading contractors by geographical distance from gas wells and concentrated demand for storage plant. In these reasons, this paper aims to develop the standardized business process model(BPM) for overseas NG pipe-line project at project planning phase to support the project entry. To this aim, first of all, extract the BPM through the broad literature and overseas construction market review and domestic/overseas pipe-line project analysis. Second, Test-bed was performed to confirm of practical applicability by 4 experts. And then 15 experts survey were performed to validate the usability and effectiveness of BPM for overseas NG pipe-line project. Consequently, if Korean contractors are using this BPM with their own know-how and experiences, it will be returned to more reasonable and rational references for decision making in overseas NG pipe-line project.

A Study on Nurses한 and Patients한 Perceptions of Psychotropic Medication (향정신성 약물치료에 대한 간호사와 환자의 지각 비교 연구)

  • 이평숙
    • Journal of Korean Academy of Nursing
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    • v.24 no.1
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    • pp.47-57
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    • 1994
  • The purpose of this study was to examine nurses’ perceptions of medication treatment for psychiatric patients and to compare these perceptions with the perceptions held by the patients. The methodology used in this study was a descriptive design with semi-structured and open-ended interviews. This study used a convenience sample of 112 nurses who worked in, and 209 patients who were under psychiatric treatment, in four hospitals attached to a university and one national mental hospital in the city of Seoul. The collected data were analyzed by SAS, using percentages for descriptive purposes, and t-test or x$^2$ for comparing the variables. The results were as follows : 1. There was no significant differences between nurses’ and patients’ perceptions on the extent to which patients complied with their medication treatment. Generally speaking, the mean compliance scores for both nurses and patients was high(nurse : (equation omitted)=3.70, Patient : (equation omitted)=3.76). 2. There was a significant difference in nurses’ and patients’ perceptions on the reasons why patients do not take medication. The nurse group indicated that the patients did not take medication because of the “worry about side effects or habituation(49.53%)”, “boredom from long-term use of medication(26.17%)” and “distrust toward medical staff(12.15% )”, but the patient group indicated that they “did not want to be dependent on medication (25%)”, “forgot to take medication(19.7%) and “worried about side effects or habituation(15.91%). 3. As for the necessity of medication, both groups showed some different responses. Even though both groups were aware of the necessity of taking medication, the patient group(21.53%) showed a more negative response. As (or the effects of medication, both groups (nurses and patients ) showed positive responses. However, the nurse group showed a higher positive response (91.07% ) than the patient group(74.16%), 5. Both the patient and nurse group indicated that the most helpful element for the patient’s life under psychiatric treatment was interviews and conversations with therapists and nurses. However, the nurse group showed a higher response(70.15%) than the patients group(47.15%). According to the patient group, family support for the patient was another important factor for psychiatric treatment and daily struggles. In conclusion, as there were differences between the perception of nurses and patients, the nurse must consider the patients’ subjective perceptions first. They should also revaluate their false belief and prejudice concerning the patients’ perceptions. Such information can provide a base to be applied by the nurses in devloping effective mutual relationships with patients which can in turn help in compliance with medication regimen. As it was confirmed that medication was the most important factor in the patients’ recovery, a thorough education program on the therapeutic effect of medication and the necessity of their continued use after discharge is also needed.

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In vitro study of compressive fracture strength of Empress 2 crowns cemented with various luting agents

  • Kim Min-Ho;Yang Jae-Ho;Lee Sun-Hyung;Chung Hun-Young;Chang Ik-Tae
    • The Journal of Korean Academy of Prosthodontics
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    • v.39 no.3
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    • pp.260-272
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    • 2001
  • All-ceramic restorations have had a more limited life expectancy than metal ceramic restorations because of their low strength. Their relatively lower strength and resistance to fracture have restricted the use of all-ceramic crowns to anterior applications where occlusal loads are lower. But there has been increasing interest in all-ceramic restorations because patients are primarily concerned with improved esthetics. Many efforts have been made to in prove the mechanical properties of dental ceramics. This study was designed to elucidate the influence of the luting agent on the strength of the Empress 2 crown (staining technique) cemented on human teeth. Seventy extracted human permanent molar teeth were chosen. Teeth were prepared for Empress 2 crowns with milling machine on a surveyor. A dental bur was placed in the mandrel that was positioned so that the long axis of the bur was perpendicular to the surveyor base. Dimensions of the Empress 2 crown preparation were $6^{\circ}$ taper on each side, $1.5{\pm}0.1mm$ shoulder margin, and 4mm crown height. The luting cements used in this study were as follow: 1. Uncemented 2. Zinc phosphate cements (Confi-Dental) 3. Conventional glass ionomer cement : Fuji 1 (GC) 4. Resin-modified glass ionomer cements : Fuji plus (GC) 5. Adhesive cements : Panavia F (Kuralay), Variolink II (Vivadent), Choice (Bisco). Fracture test using Instron. The crowns were loaded in compressive force to evaluate the effect of these cements on the breaking strength of these all-ceramic crowns. A steel ball with a diameter of 4mm was placed on the occlusal surface and load was applied to the steel ball by a cylindrical bolt with a crosshead speed of 0.5mm per minute until fracture occurred. The fractured surface was examined using Scanning Electron Microscopic Image (SEM) to discover the correlation between fracture strength and bonding capacity. Within the limitation of this in vitro study design, the results were as follows : 1. fomentations significantly increased the fracture resistance of Empress ceramic crowns compared to control. Uncemented (206.9 N): ZPC (812.9 N): Fuji 1 (879.5 N): Fuji Plus (937.7 N): Choice (1105.4 N): Variolink II (1221.1 N): Panavia F (1445.2 N). 2. Resin luting agent, treated by a silane bond enhancing agents, yielded a significant increase in fracture resistance. In some of the Panavia F group, a fracture extended into dentin. 3. According to SEM images of fractured Empress crowns, the stronger the bond at both interfaces(crown and die), the more fracture strength was acquired.

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Electrochemical Characteristics of Ru Added Li4Ti5O12 as an Anode Material (Ru를 첨가한 음극활물질 Li4Ti5O12의 전기화학적 특성)

  • Cho, Woo-Ram;Na, Byung-Ki
    • Clean Technology
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    • v.20 no.4
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    • pp.433-438
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    • 2014
  • There is an increasing interest in the development of rechargeable batteries suitable for use in both hybrid electric vehicles and energy storage systems that require higher charge & discharge rates, bigger battery sizes and increased safety of the batteries. Spinel-type lithium titanium oxide ($Li_4Ti_5O_{12}$) as a potential anode for lithium ion batteries has many advantages. It is a zero-strain materials and it experiences no structural change during the charge/discharge precess. Thus, it has long cycle life due to its structural integrity. It also offers a stable operation voltage of approximately 1.55 V versus $Li^+/Li$, above the reduction potential of most organic electrolyte. In this study, Ru added $Li_4Ti_5O_{12}$ composites were synthesized by solid state process. The characteristics of active material were investigated with TGA-DTA, XRD, SEM and charge/discharge test. The capacity was reduced when Ru was added, however, the polarization decreased. The capacity rate of $Li_4Ti_5O_{12}$ with Ru (3%, 4%) addition was reduced during the charge/discharge precess with 10 C-rate as a high current density.

A New Rose Cultivar, 'Pretty You' with Vigorous Growth Habit (생육속도가 빠른 장미 신품종 '프리티유')

  • Lee, Young Soon;Jung, Yun Kyung;Lee, Sang Deok;Park, Mi Yok
    • Korean Journal of Breeding Science
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    • v.43 no.6
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    • pp.524-527
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    • 2011
  • A new rose cultivar, 'Pretty You' was selected from the progenies of a cross between 'Red Sandra' and 'Mira Bai' by rose breeding team of the Gyeonggi-Do Agricultural Research and Extension Services in 2008. 'Pretty You' was crossed in 2005 and seedlings were produced. After the test of specific characters from 2006 to 2008, it was finally selected and named. 'Pretty You' a stand type with large sized flower, has red and pink color (main color: Red Group 52B, second color: Red Group 50A) flower. 'Pretty You' grows vigorously, it took 45.8 days from pruning to blooming and cut flower productivity is $142.8stems/m^2$ in a year. The length of cut flower is 69.2 cm. It has 11.7 cm in flower diameter and 32.1 in petal numbers per flower. Vase life of the this cultivar can be as long as 12.3 days.