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http://dx.doi.org/10.7845/kjm.2015.4082

The influence of various medicines and nutritional supplements against bacteria with gastrointestinal relevance  

Park, Jae Eun (College of Pharmacy, Sahmyook University)
Lee, Do Kyung (College of Pharmacy, Sahmyook University)
Ha, Nam Joo (College of Pharmacy, Sahmyook University)
Song, Young Cheon (College of Pharmacy, Sahmyook University)
Publication Information
Korean Journal of Microbiology / v.51, no.1, 2015 , pp. 61-67 More about this Journal
Abstract
Recently, change of Western pattern diet and lifestyle is caused by various metabolic disorders and chronic diseases. These diseases need to take medicine regularly. Also, many people take health functional food, various vitamins and nutritional supplements in order to maintain a healthy life. But, there was no study about affects taking medicines against bacteria with gastrointestinal relevance. This study was performed by antibacterial activity test to evaluate the influence of a long time or commonly used medication. As a result, medicines of Vitamins & Minerals or Central nervous system show antibacterial activity against beneficial enteric bacteria and harmful enteric bacteria. Dexibuprofen of the Anti-inflammatory Drugs that acts on the central nervous system has shown high antibacterial activity at beneficial enteric bacteria strains (Lactobacillus casei, Lactobacillus rhamnosus) and harmful enteric bacteria (Staphylococcus aureus). Also, fenofibric acid of the antilipemic agents that acts on the Cardiovascular & Hematopoietic system has shown high antibacterial activity at beneficial enteric bacteria strains (Lactobacillus casei). Vitamins & Minerals appeared antibacterial activity against most intestinal bacteria. Vitamin B-Complex/with C and vitamin C were especially high with beneficial enteric bacteria strains (Bifidobacterium infantis) and harmful enteric bacteria (E. coli, E. aerogenes, S. flexneri, S. Typhimurium, S. aureus). Therefore, these results indicate that variously taking medicines have generally antibacterial activity against harmful enteric bacteria strains and beneficial enteric bacteria strains.
Keywords
antibacterial activity; beneficial enteric bacteria; harmful enteric bacteria;
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