• Korean Journal of Plant Resources
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• v.25 no.4
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• pp.465-472
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• 2012

We examined plants that were used as temple food in Jeju from May 2011 to January 2012. Thirty-six temples participated in the study, and there were 58 questionnaire respondents. Fifty-seven taxa were used as temple food, which belonged to 27 families, 51 genera, 55 species, and two varieties. The most commonly used family-based taxa were eight species of Compositae, six species of Cruciferae, and four species of Umbelliferae. Ten species of woody plants and 25 species of Jeju native plants were also used as temple food. The most useful part was the leaf, followed by the root, leaflet, and fruit. A patent search showed that most of the surveyed plants were covered by intellectual property rights. Forty-eight species had food-related patents, 34 species had cosmetics-related patents, and 38 species had medicine-related patents. The purchase and procurement of Jeju temple food plants usually depended on the market or plant cultivation rather than the use of the plants. Gathering of wild herbs for temple food has been performed on a limited basis. Therefore, collecting traditional knowledge for the use of Jeju plant resources should be conducted under different conditions rather than through a temple-related study.

• Journal of Life Science
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• v.22 no.12
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• pp.1729-1739
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• 2012

The aim of this study was to evaluate the clinical efficacy and safety of fermented medicinal herbs. A search of the China National Knowledge Infrastructure (CNKI), PubMed databases and Korean Journal of Oriental Medicine in 2000-2011 located 11 randomized controlled trials (RCTs) that investigated the clinical efficacy of fermented medicinal herbs. Domestic RCTs reported clinical efficacy on improvement of immune responses and clinical safety on usage of fermented medicinal herbs in subjects suffering from cerebral hemodynamics. Countries other than Chinareported studies on the cause of esophageal cancer and on local inflammatory reactions. In China, studies were reported on the effectiveness of fermented medicinal herbs on scapulohumeral periarthritis of the stasis type, chronic superficial gastritis, dysuria induced by benign prostatic hyperplasia of deficiency of kidney yang, diabetic nephropathy, essential hypertension, and benign prostate hyperplasia. These results indicate that fermented medicinal herbs have obvious clinical effects in some diseases and no adverse reactions. Therefore, we need to initiate more fermentation research with useful bacteria, fungi, and mushrooms to produce fermented medicinal herbs. Both governments and research authorities should focus on research involving fermentation of medicinal herbs.

• Journal of Pharmacopuncture
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• v.18 no.2
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• pp.7-18
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• 2015

Objectives: Lawsone (1,4 naphthoquinone) is a non redox cycling compound that can be catalyzed by DT diaphorase (DTD) into 1,2,4-trihydroxynaphthalene (THN), which can generate reactive oxygen species by auto oxidation. The purpose of this study was to evaluate the toxicity of the phytomarker 1,4 naphthoquinone and its metabolite THN by using the molecular docking program AutoDock 4. Methods: The 3D structure of ligands such as hydrogen peroxide ($H_2O_2$), nitric oxide synthase (NOS), catalase (CAT), glutathione (GSH), glutathione reductase (GR), glucose 6-phosphate dehydrogenase (G6PDH) and nicotinamide adenine dinucleotide phosphate hydrogen (NADPH) were drawn using hyperchem drawing tools and minimizing the energy of all pdb files with the help of hyperchem by $MM^+$ followed by a semi-empirical (PM3) method. The docking process was studied with ligand molecules to identify suitable dockings at protein binding sites through annealing and genetic simulation algorithms. The program auto dock tools (ADT) was released as an extension suite to the python molecular viewer used to prepare proteins and ligands. Grids centered on active sites were obtained with spacings of $54{\times}55{\times}56$, and a grid spacing of 0.503 was calculated. Comparisons of Global and Local Search Methods in Drug Docking were adopted to determine parameters; a maximum number of 250,000 energy evaluations, a maximum number of generations of 27,000, and mutation and crossover rates of 0.02 and 0.8 were used. The number of docking runs was set to 10. Results: Lawsone and THN can be considered to efficiently bind with NOS, CAT, GSH, GR, G6PDH and NADPH, which has been confirmed through hydrogen bond affinity with the respective amino acids. Conclusion: Naphthoquinone derivatives of lawsone, which can be metabolized into THN by a catalyst DTD, were examined. Lawsone and THN were found to be identically potent molecules for their affinities for selected proteins.

• Journal of Intelligence and Information Systems
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• v.14 no.1
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• pp.117-129
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• 2008

The cost-based scheduling work has been done in both the Operations Research (OR) and Artificial Intelligence (AI) literature. To deal with more realistic problems, AI-based heuristic scheduling approach with non-regular performance measures has been studied. However, there has been little research effort to develop a full inter-job cost propagation algorithm (CPA) for different jobs having multiple downstream and upstream activities. Without such a CPA, decision-making in scheduling heuristics relies upon local, incomplete cost information, resulting in poor schedule performance from the overall cost minimizing objective. For such a purpose, we need two types of CPAs : intra-job CPA and inter-job CPA. Whenever there is a change in cost information of an activity in a job in the process of scheduling, the intra-job CPA updates cost curves of other activities connected through temporal constraints within the same job. The inter-job CPA extends cost propagation into other jobs connected through precedence relationships. By utilizing the cost information provided by CPAs, we propose cost-based scheduling heuristics that attempt to minimize the total schedule cost. This paper develops inter-job CPAs that create and update cost curves of each activity in each search state, and propagate cost information throughout a whole network of temporal constraints. Also we propose various cost-based scheduling heuristics that attempt to minimize the total schedule cost by utilizing the cost propagation algorithm.

• Journal of KIISE:Software and Applications
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• v.29 no.1_2
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• pp.80-90
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• 2002

Clustering is a useful technique for grouping data points such that points within a single group/cluster have similar characteristics. Many clustering algorithms have been developed and used in engineering applications including pattern recognition and image processing etc. Recently, it has drawn increasing attention as one of important techniques in data mining. However, clustering algorithms such as K-means and Fuzzy C-means suffer from difficulties. Those are the needs to determine the number of clusters apriori and the clustering results depending on the initial set of clusters which fails to gain desirable results. In this paper, we propose a new clustering algorithm, which solves mentioned problems. In our method we use evolutionary algorithm to solve the local optima problem that clustering converges to an undesirable state starting with an inappropriate set of clusters. We also adopt a new measure that represents how well data are clustered. The measure is determined in terms of both intra-cluster dispersion and inter-cluster separability. Using the measure, in our method the number of clusters is automatically determined as the result of optimization process. And also, we combine heuristic that is problem-specific knowledge with a evolutionary algorithm to speed evolutionary algorithm search. We have experimented our algorithm with several sets of multi-dimensional data and it has been shown that one algorithm outperforms the existing algorithms.

• Korean Journal of Comparative Education
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• v.26 no.4
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• pp.173-198
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• 2016

The purpose of this study is to analyze the characteristics of Educational Reforms Policy in lately Japan and to evaluate it. Especially focus on the activities of the [MEXT; Ministry of Education, Culture, Sports, Science and Technology] and [CCE;The Central Council for Education] This article composed of five chapters; Implication and problem situation, History of the Japanese educational reforms, the characteristics in the site of process of educational reforms policy, evaluation on the main policies, and Conclusion(contain the suggestion for Korea). The method of study composed of the literature search and interview. The System Analysis[input-process-output-feedback] is used as a model of the analyze the characteristics of educational reforms policy. By the new Basic Act on Education, the principles of educational administration is changed. Education administration shall be carried out in a fair and proper manner through appropriate role sharing and cooperation between the national and local governments(Article 16). As a conclusion, The initiative in the establishment of educational reform plans has gone over to the cabinet side from MEXT. And evaluate the five policies. That is Japan's Basic Plan for the Promotion of Education, The new Basic Act on Education(enacted on 2006), Provincial Governor's (Tokyo & Oska) Educational Reform Plan, Reform plan of the Boards of Education, and Improvement Policy of the Quality of Teachers.

• Journal of Family Resource Management and Policy Review
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• v.25 no.4
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• pp.31-41
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• 2021

This study was conducted to determine how the family relationships of the middle-aged affect their life satisfaction and how family support services regulate the association between the two factors. A total of 8,695 middle-aged residents(aged 50 to 64 years) were chosen from among resident-respondents of the needs survey administered to establish the 4th local social security plan in Gyeonggi-do. The moderating effect of family support services on the relation between family relationship difficulties and life satisfaction was investigated. The analysis showed that the life satisfaction experienced by the middle-aged is slightly higher than the middle level. The lower the difficulty in family relationships, the higher the use of family support services, the more women than men, and the better the economy, the higher the life satisfaction of middle-aged. As a moderating variable, family support services significantly moderate the effects of family relationship difficulties experienced by the middle-aged on life satisfaction. The results are meaningful in that they comprehensively shed light on the difficulties that confront family relationships and the relationship structure of family support services, thereby contributing to the search for life satisfaction among the middle-aged in Gyeonggi-do.

• Journal of Korean Medical Ki-Gong Academy
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• v.20 no.1
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• pp.15-67
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• 2020

Objective : The purpose of this study is to identify the trends of vibration(or wave) therapy in Korea, to actively utilize vibration(or wave) therapy, and to help research activities of vibration therapy in Korean Medicine. Methods : The following Korean words "진동기", "진동요법", "진동운동", "진동치료", "파동요법", "파동운동", "파동치료" were searched on three specialized search sites (RISS, NAL, DBpia). Trends of vibration therapy were analyzed through the selected researches suitable for this study among these searched researches in an overview format. Results : 1. A total of 8,116 studies were searched and a total of 365 studies were finally selected 2. From 2000 to 2019, when research began to increase in earnest, there were 17.45±10.28 studies per year, and the AGR(Average Annual Growth Rate) was 11.92%. 3. In the main field of research, the 'Medicine and Pharmacy' was the largest with 147(40.16%) studies. In the Middle Field, the 'Kinesiology' was the largest with 99(27.05%) studies. In the study design, 'RCT(Randomized Controlled trial)' was the largest with 138(47.75%) studies. In the Age Group, 'Youth' was the largest with 126(48.84%) studies. 4. The average of the number of participants was 24.90±17.44. 5. The most used Intervention was the 'WBV(Whole Body Vibration)' with 177(61.25%) studies. 6. The average of Intervention Period was 5.99±4.14 weeks, while the maximum was 36 weeks. 7. The journal that published the most research papers is 'K. J. of Sports Science(체육과학연구;13)', and the society is 'Rehabilitation Engineering And Assistive Technology Society of Korea(한국재활복지공학회; 14)'. The University that published the most dissertations is 'Sahmyook University(11)'. 8. The authors who published the most studies are Ju-Hwan O(8) as the main author and Tae Kyu Kwon(18) as the co-author (including the thesis Director). In an integrated analysis of the authors and co-authors, Tae Kyu Kwon published the most numerous studies(19) Conclusions : 1. The study of vibration or wave therapy has been increasing noticeably every year. 2. The major academic Fields studying vibration or wave therapy are the 'Kinesiologic Field', 'Physical Therapy Field', and 'Biomedical Engineering Field'. 3. The most chosen method of study design on vibration or wave treatment was 'RCT', and there was no significant change in the annual presentation rate. 4. Types of vibration or wave therapy could be classified as 'LVS(Local Vibration Stimulation)', 'WBV(Whole Body Vibration)', 'MV(Micro Vibration)', 'BV(Bio Vibration)' and 'SWV(Sound Wave Vibration)', and the study on Whole Body Vibration is most active. 5. Most of the studies of vibration or wave therapy were on musculoskeletal systems, but there were very few studies on internal diseases.

• International Area Studies Review
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• v.22 no.3
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• pp.293-317
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• 2018

In the era of glocalization, the role of the state is gradually being reduced and the roles of cities and regions are becoming more critical, especially for the everyday life of residents. Many attempts have been made to secure regional competitiveness based on local identity, to differentiate it from other cities and regions, and to search for methods of sustainable development. The importance of place, which affects human life-world, is getting to garner more attention whereas the large-scale development-centered approach has becoming less prominent. The objective of the study is to investigate the concept of place-making and to apply for the East Asian regions, which seems to be differentiated from urban cultural frameworks of the West. The paper employs comparative methodology for the placemaking strategies of the three case locations, say Mok-dong in Seoul, Koganecho in Yokohama and red town in Shanghai. By through examining the three stages of place-making for each three place, it reveals that cultural identity is quintessential in the East-Asian region. In conclusion, it suggests a sustainable place-making strategies for urban areas in East-Asian regional setting.

• Journal of Food Hygiene and Safety
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• v.36 no.4
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• pp.331-341
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• 2021

DNA barcode sequences of commercial seafood products, which are difficult to morphologically discriminate, were analyzed to determine cases of food fraud. The gene sequences were analyzed by amplifying the COX I (cytochrome C oxidase subunit I) gene region of mitochondrial DNA, which is mainly used for species identification. The DNA barcode sequences were compared with the gene sequence of each fish registered in the US National Center for Biotechnology. A total of 46 processed seafood products (12 Pagrus majo, 4 Oplegnathus fasciatus, 7 Dentex tumifrons, 2 Acanthopagrus schlegelii, 7 Oreochromis niloticus, 6 Branchiostegus japonicus, 8 Branchiostegus albus) were investigated. Having DNA sequence identity of more than 97% was judged as the same species. As a result of this study, no cases of forgery and alteration were detected. However, some disparities in the commercial names used in local markets and the standard names given in the Korea Food Code were found, which may cause confusion for consumers. It is therefore suggested that the standard name or scientific name be displayed on seafood product labels.