• The Korean Journal of Pain
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• v.7 no.2
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• pp.217-221
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• 1994

Percutaneous neurolysis of upper thoracic sympathetic ganglion was performed in 40 patients by simultaneously injecting 3 ml of pure alcohol into the T2 and T3 levels after 3 ml of injection of local anesthetic agent on the same sites. Using a skin temperature probe, finger tip temperatures were measured on the index finger ipsilateral to the nerve block before block, 15 and 30 minutes after test block, and 30 minutes after alcohol block. Alcohol block was performed immediately after 30 minutes test block. Finger tip temperatures obtained at 30 minutes post alcohol block and test block and the differences in the temperatures measured before and 30 minutes after alcohol block were shown to be statistically important as potential indicators for prediciting long term outcome of therapy for palmar hyperhidrosis using this technique. These results demonstrate that the palmar temperature monitoring method is sufficiently sensitive to predict the outcome of nerve block during and after thoracic sympathetic ganglion block.

• Journal of Internet Computing and Services
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• v.7 no.4
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• pp.33-43
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• 2006

This paper proposes a method to extract coronary arteries effectively in the angiography, In general. DSA(Digital Subtraction Angiography) is a well-established technique for the visualization of coronary arteries, DSA involves the subtraction of a mask image, an image of a heart before the injection of contrast medium, from a live image, However, this technique is sensitive to the movement of background and can cause wrong detection due to the variance of background intensity between two images. Therefore, this paper solves the structural problem resulted from background movement by selecting an image which has the least difference of movement through the similarity analysis of background texture, and it extracts only the blood vessels effectively through local intensity correction of the selected images, Experimental results show that the proposed method has the lower false-detection rate and higher accuracy rate than existing methods.

• Korean Journal of Veterinary Research
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• v.52 no.3
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• pp.157-162
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• 2012

Corneal injury is very common clinical condition in veterinary medicine and delayed or incomplete corneal healing has the potential of vision loss due to the loss of corneal transparency. For the reconstruction of corneal epithelium, tissue graft and cell transplantation have been prosperously investigated. The purpose of this study was to evaluate the clinical value and short-term safety of application of cultured allogenic mesenchymal stem cells (MSCs) in the treatment of canine experimental corneal defect. Corneal defects were surgically generated in the central corneas of healthy beagle dogs and cultured canine allogenic MSCs were transplanted via subconjunctival injection. Although mean healing time, the rate of epithelial regeneration, and the degree of corneal transparency were not significantly improved after MSC transplantation, significant immune reaction or incompatibility reaction was not detected except transient local irritation. These results propose the possibility of MSC application as a new regenerative medicine in canine ocular disorders.

• Nuclear Engineering and Technology
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• v.32 no.1
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• pp.34-45
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• 2000

This study is concerned with the experimental test and numerical analysis of the heat transfer and solidification of the molten metal pool with overlying coolant with boiling. In the test, the metal pool is heated from the bottom surface and coolant is injected onto the molten metal pool. Experiments were performed by changing the test section bottom surface temperature of the metal layer and the coolant injection rate. The two-phase boiling coolant experimental results are compared against the dry test data without coolant or solidification of the molten metal pool, and against the crust formation experiment with subcooled coolant. Also, a numerical analysis is performed to check on the measured data. The numerical program is developed using the enthalpy method, the finite volume method and the SIMPLER algorithm. The experimental results of the heat transfer show general agreement with the calculated values. The present empirical test and numerical results of the heat transfer on the molten metal pool are apparently higher than those without coolant boiling. This is probably because this experiment was performed in concurrence of solidification in the molten metal pool and the rapid boiling of the coolant. The other experiments were performed without coolant boiling and the correlation was developed for the pure molten metal without phase change.

• Nuclear Engineering and Technology
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• v.48 no.5
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• pp.1174-1183
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• 2016

Hydrogen release during severe accidents poses a serious threat to containment integrity. Mitigating procedures are necessary to prevent global or local explosions, especially in large steel shell containments. The management of hydrogen safety and prevention of over-pressurization could be implemented through a hydrogen reduction system and spray system. During the course of the hypothetical large break loss-of-coolant accident in a nuclear power plant, hydrogen is generated by a reaction between steam and the fuel-cladding inside the reactor pressure vessel and also core concrete interaction after ejection of melt into the cavity. The MELCOR 1.8.6 was used to assess core degradation and containment behavior during the large break loss-of-coolant accident without the actuation of the safety injection system except for accumulators in Beznau nuclear power plant. Also, hydrogen distribution in containment and performance of hydrogen reduction system were investigated.

• The Korean Journal of Pain
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• v.25 no.1
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• pp.55-59
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• 2012

Lumbar spinal stenosis is a commonly treated with epidural injections of local anesthetics and corticosteroids, however, these therapies may relieve leg pain for weeks to months but do not influence functional status. Furthermore, the majority of patients report no substantial symptom change over the repeated treatment. Utilizing balloon catheters, we successfully treated with three patients who complained persistent symptoms despite repeated conventional steroid injections. Our results suggest that transforaminal decompression using a balloon catheter may have potential in the nonsurgical treatment of spinal stenosis by modifying the underlying pathophysiology.

• The Korean Journal of Physiology and Pharmacology
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• v.11 no.5
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• pp.221-226
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• 2007

Melittin-induced tonic pain model is characterized by local inflammation, edema, spontaneous flinchings, and sustained mechanical hypersensitivity. These nociceptive responses are mediated through selective activation of capsaicin-sensitive primary afferent fibers by melittin. The present study was undertaken to elucidate the role of peripheral 5-hydroxytryptamine(5-HT) receptors in the melittin-induced nociceptive responses. Changes in mechanical threshold, flinching behaviors and paw thickness were measured in rat intraplantarly injected with melittin($40{\mu}g/paw$) alone or treated together with melittin and 5-HT receptor antagonists. WAY-100635($100{\mu}g\;&\;200{\mu}g/paw$), isamoltane hemifumarate($100{\mu}g\;&\;200{\mu}g/paw$), methysergide maleate($60{\mu}g,\;120{\mu}g\;&\;200{\mu}g/paw$) and ICS-205,930($100{\mu}g\;&\;200{\mu}g/paw$) were intraplantarly injected 20 min before melittin injection. All 5-HT receptor antagonists tested in this experiment significantly attenuated the ability of melittin to reduce mechanical threshold and to induce flinching behaviors. 5-HT receptor antagonists, except ICS-205,930, had mild inhibitory effect on melittin-induced edema. These experimental findings suggest that multiple peripheral 5-HT receptors are involved in the melittin-induced nociceptive responses.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2003.05a
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• pp.225-232
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• 2003

With an aim placed on its exploitation on practical injector design, liquid phase mixing due to unlike split triplet impinging element is experimentally investigated by a series of cold tests. Non-reacting kerosene/water spray simulates the kerosene/LOX propellant combination. Measurements of local mixture ratio distribution were made for different injection configurations and different momentum ratios. Mixing and mixing controlled characteristic velocity efficiencies are measured in terms of oxidizer/fuel jet momentum ratio from 0.5 to 8. Extent of mixing and its influence on hot performance are estimated in terms of mixing efficiency and mixing controlled characteristic velocity. Envelope of design locus for optimum mixing quality and corresponding maximum hot performance are proposed. Effects of momentum ratio, orifice diameter ratio and jet velocity ratios are also presented and discussed.

• Journal of the Korean Chemical Society
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• v.57 no.6
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• pp.755-760
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• 2013

The present study is synthesis of derivatives of N'-(4-amino-5-sulfanyl-4H-1,2,4-triazole-3-yl)-2-(1H-benzimidazole-2-ylsulfanyl) acetohydrazide (IV). Antibacterial activity tested against the E. coli and A. Substilis. Biological activities conducted by disc diffusion method. Compound $2MB_1$, $2MB_3$, $2MB_5$ inhibit the appreciable microbial growth while rest of the compound possess the moderate activities. Anti-inflammatory activity tested by reduces local edema induced in the rat paw by injection of phlogestic agent. Compound $2MB_1$, $2MB_8$, $2MB_5$, $2MB_3$ and $2MB_6$ exhibit satisfying anti-inflammatory activity while analgesic activity conducted by acetic acid induced writhing effect in mice while compound $2MB_1$, $2MB_4$ and $2MB_7$ having the good analgesic activity. The chemical structures of all newly synthesized compounds were confirmed by their IR, $^1H$ NMR and mass spectral data.

• Geosciences Journal
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• v.22 no.6
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• pp.1041-1052
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• 2018

A single-well push-drift-pull tracer test using two different tracers ($SF_6$ and salt) was performed at the Environmental Impact Test (EIT) site to determine suitable locations for monitoring wells and arrange them prior to artificial $CO_2$ injection and leak tests. Local-scale estimates of hydraulic properties (linear groundwater velocity and effective porosity) were obtained at the study site by the tracer test with two tracers. The mass recovery percentage of the volatile tracer ($SF_6$) was lower than that of the non-volatile tracer (salt) and increased drift time may make degassing of $SF_6$ intensified. The $CO_2$ leakage monitoring results for both unsaturated and saturated zones suggest that the $CO_2$ monitoring points should be located near points at which a high concentration gradient is expected. Based on the estimated hydraulic properties and tracer mass recovery rates, an optimal $CO_2$ monitoring network including boreholes for monitoring the unsaturated zone was constructed at the study site.