• Title/Summary/Keyword: Local cooling

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In vivo verification of regional hyperthermia in the liver

  • Noh, Jae Myoung;Kim, Hye Young;Park, Hee Chul;Lee, So Hyang;Kim, Young-Sun;Hong, Saet-Byul;Park, Ji Hyun;Jung, Sang Hoon;Han, Youngyih
    • Radiation Oncology Journal
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    • v.32 no.4
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    • pp.256-261
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    • 2014
  • Purpose: We performed invasive thermometry to verify the elevation of local temperature in the liver during hyperthermia. Materials and Methods: Three 40-kg pigs were used for the experiments. Under general anesthesia with ultrasonography guidance, two glass fiber-optic sensors were placed in the liver, and one was placed in the peritoneal cavity in front of the liver. Another sensor was placed on the skin surface to assess superficial cooling. Six sessions of hyperthermia were delivered using the Celsius TCS electro-hyperthermia system. The energy delivered was increased from 240 kJ to 507 kJ during the 60-minute sessions. The inter-session cooling periods were at least 30 minutes. The temperature was recorded every 5 minutes by the four sensors during hyperthermia, and the increased temperatures recorded during the consecutive sessions were analyzed. Results: As the animals were anesthetized, the baseline temperature at the start of each session decreased by $1.3^{\circ}C$ to $2.8^{\circ}C$ (median, $2.1^{\circ}C$). The mean increases in temperature measured by the intrahepatic sensors were $2.42^{\circ}C$ (95% confidence interval [CI], 1.70-3.13) and $2.67^{\circ}C$ (95% CI, 2.05-3.28) during the fifth and sixth sessions, respectively. The corresponding values for the intraperitoneal sensor were $2.10^{\circ}C$ (95% CI, 0.71-3.49) and $2.87^{\circ}C$ (1.13-4.43), respectively. Conversely, the skin temperature was not increased but rather decreased according to application of the cooling system. Conclusion: We observed mean $2.67^{\circ}C$ and $2.87^{\circ}C$ increases in temperature at the liver and peritoneal cavity, respectively, during hyperthermia. In vivo real-time thermometry is useful for directly measuring internal temperature during hyperthermia.

Determination of Optimal Storage Condition for Pre-packed Hanwoo Loin

  • Seol, Kuk-Hwan;Park, Tu San;Oh, Mi-Hwa;Park, Beom-Young;Cho, Seong In;Lee, Mooha
    • Food Science of Animal Resources
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    • v.33 no.3
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    • pp.390-394
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    • 2013
  • The aim of this study was to determine the optimal storage condition of pre-packed Hanwoo beef without freezing. Hanwoo loin was purchased from a local distributor at 48 h after slaughter, then sliced in $1.5{\pm}0.5$ cm thickness, and packed in a polyethylene (PE) tray covered with linear low-density polyethylene (LLDPE) film. The studied factors to set the optimal storage condition were chamber temperature (5, 2.5 and $-1^{\circ}C$ for 14 d), cooling method (direct and indirect cooling system), and ultraviolet (UV) light irradiation for beef surface sterilization (0, 30, 60, and 120 min). The changes of pH, thiobarbituric acid reactive substances (TBARS) and number of aerobic bacteria were measured during storage. Beef samples stored in $-1^{\circ}C$ showed the minimal increasing rate in TBARS and microbial growth. After 15 d of storage, there was no significant difference in pH and TBARS values. However, the microbial population of beef stored in direct type cooling chamber ($4.25{\pm}0.66$ Log CFU/g) was significantly lower than that of beef stored in indirect type chamber ($6.47{\pm}0.08$ Log CFU/g) (p<0.05). After 4 d of storage, 60 or 120 min UV light irradiated beef samples showed significantly lower microbial population, and at 14 d of storage, 60 min UV irradiated beef sample showed significantly lower microbial population ($3.14{\pm}0.43$ Log CFU/g) than control ($4.46{\pm}0.13$ Log CFU/g) (p<0.05). However, TBARS values of 60 or 120 min UV light irradiated beef samples were significantly higher than non-irradiated beef sample after 4 d of storage (p<0.05).

Numerical Simulation on the Wind Ventilation Lane and Air Pollutants Transport due to Local Circulation Winds in Daegu Districts (대구지역의 국지순환풍의 환기경로 및 대기오염수송에 관한 수치모의)

  • Koo, Hyun-Suk;Kim, Hae-Dong
    • Journal of the Korean earth science society
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    • v.25 no.6
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    • pp.418-427
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    • 2004
  • Recently, urban planning with consideration of urban climate, represented by the concept of urban ventilation lane is widely practiced in many countries. The concept of urban ventilation lane is mainly aimed to improve the thermal comfort within urban area in summer season. It has also the aim to reduce the urban air pollution by natural cold air drainage flows which are to be intensified by a suitable alignment of buildings as well as use zonings based on scientific reasons. In this study, the prevailing wind ventilation lane of a local wind circulation and around Daegu for a typical summer days was investigated by using a numerical simulation. The transport of air pollutants by the local circulation winds was also investigated by using the numerical simulation model, the RAMS (Reasonal Atmospheric Model System).The domain of interest is the vicinity of Daegu metropolitan city (about 900 km2). The horizontal scale of the area is about 30 km. The simulations were conducted under a late spring synoptic condition with weak gradient wind and almost clear sky. From the numerical experiment, the following three conclusions were obtained: (1) The major wind passages of the local circulation wind generated by radiative cooling over the representative mountains of Daegu (Mt. Palgong and Mt. Ap) were found. The winds blow down along the valley axis over the eastern part of Daegu as a gravity flow during nighttime. (2) At the flatland, the winds blow toward the western part of Daegu through the city center. (3) As the results, the air pollutants were transported toward the western part of Daegu by the winds during nighttime.

HOT GAS HALOS IN EARLY-TYPE GALAXIES AND ENVIRONMENTS

  • Kim, Eunbin;Choi, Yun-Young;Kim, Sungsoo S.
    • Journal of The Korean Astronomical Society
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    • v.46 no.1
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    • pp.33-40
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    • 2013
  • We investigate the dependence of the extended X-ray emission from the halos of optically luminous early-type galaxies on the small-scale (the nearest neighbor distance) and large-scale (the average density inside the 20 nearest galaxies) environments. We cross-match the 3rd Data Release of the Second XMMNewton Serendipitous Source Catalog (2XMMi-DR3) to a volume-limited sample of the Sloan Digital Sky Survey (SDSS) Data Release 7 with $M_r$ < -19.5 and 0.020 < z < 0.085, and find 20 early-type galaxies that have extended X-ray detections. The X-ray luminosity of the galaxies is found to have a tighter correlation with the optical and near infrared luminosities when the galaxy is situated in the low large-scale density region than in the high large-scale density region. Furthermore, the X-ray to optical (r-band) luminosity ratio, $L_X/L_r$, shows a clear correlation with the distance to the nearest neighbor and with large-scale density environment only where the galaxies in pair interact hydrodynamically with seperations of $r_p$ < $r_{vir}$. These findings indicate that the galaxies in the high local density region have other mechanisms that are responsible for their halo X-ray luminosities than the current presence of a close encounter, or alternatively, in the high local density region the cooling time of the heated gas halo is longer than the typical time between the subsequent encounters.

Effects of Humidity and Velocity on Frost Distribution Characteristics of Humid Air Flow on Cold Surfaces (차가운 표면위에서의 습공기 유동의 습도 및 속도가 착상분포 특성에 미치는 영향)

  • Kwon Jeong-Tae;Rew Keun-Ho;Lim Hyo-Jae;Han Ji-Won;Kwon Young Chul
    • Journal of Energy Engineering
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    • v.14 no.4 s.44
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    • pp.213-218
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    • 2005
  • In order to understand the heat and mass transfer characteristics of humid airflow in frosting conditions, a flat plate of aluminum with cooling modules located in the central part of the plate was used. A microscope system (resolution of 0.05 mm) was used for the measurement of local thickness of frost at seven points along the plate in the flow direction. For the total mass of frost at each test operation, an electronic balance (resolution of 1 mg) was used. The local frost thickness distributions far various test conditions were presented along with the frost mass data measured at the given operating times. The effect of humidity and velocity of humid air on frosting were analyzed.

An Experimental Study on Frosting of Humid Air-flow on a Surface with Local Cooling for Heat Exchanger Design (열교환기 설계를 위한 국소 냉각 표면위에서의 습공기 유동의 착상실험)

  • Kwon, Jeong-Tae;Lim, Hyo-Jae;Park, Kyoung-Woo;Kim, Chang-Eob;Kim, Kyung-Min;Kwon, Young-Chul
    • Journal of Energy Engineering
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    • v.17 no.1
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    • pp.1-7
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    • 2008
  • The present study has been conducted to understand the heat and mass transfer characteristics of humid airflow in frosting conditions. A flat plate of aluminum was used for the simulation of flat surface part of the fin of the heat exchanger. The aluminum surface temperatures were measured and analyzed to clarify the heat and mass transfer characteristics under frosting conditions. Also, the pressure drops were measured to clarify the air-blocking effect of frost in the mini channel of the air-side hoot exchangers. A data reduction method was developed far the analysis of local characteristics of humid air under frosting conditions.

Observation of the Cold-air Drainage and Thermal Belt Formation in a Small Mountainous Watershed by Using an Infrared Imaging Radiometer (적외선 영상 복사계를 이용한 산간집수역의 찬공기 배수와 온난대 형성 관측)

  • Yun, Jin-I.
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.13 no.2
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    • pp.79-86
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    • 2011
  • Cold-air drainage and pooling occur in most mountain valleys at night. Local climates with cold-air pooling could affect phenology and distribution of crop plants. A high resolution infrared imaging radiometer was used to visualize the cold-air drainage and thermal belt formation over a small mountainous watershed (ca. $10{\times}5{\times}1$ km for the maximum length${\times}$width${\times}$depth). Thermal images on $640{\times}480$ pixels were scanned across the Akyang valley (south of Mt. Jiri National Park) by the radiometer installed at a local peak ('Hyongjebong', 1,117 m a.s.l.) at dawn of 17 May 2011, when the synoptic condition was favorable for the surface cooling and cold-air drainage. Major findings are: (1) Cold-air drainage and accumulation was clearly identified by the lowest brightness temperature mainly at the valley bottom. (2) So-called 'thermal belt' with higher brightness temperature was found partway up the valley sidewalls and showed up to $5^{\circ}C$ departure from the valley bottom temperature. (3) Digital thermography showed feasibility for validation of the high definition geospatial temperature models currently in use for the plot-specific agrometeorological service.

The heat transfer and pressure drop characteristics of $CO_2$ during supercritical region in a horizontal tube (초임계 영역에서 수평관내 $CO_2$ 열전달과 압력강하)

  • 이동건;오후규;김영률;손창효
    • Journal of Advanced Marine Engineering and Technology
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    • v.28 no.3
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    • pp.500-508
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    • 2004
  • The heat transfer coefficients during gas cooling process of carbon dioxide in a horizontal tube were investigated. The experiments are conducted without oil in the refrigerant loop. The main components of the refrigerant loop are a receiver, a variable-speed pump, a mass flow meter, a pre-heater, and a gas cooler(test section). The water loop consists of a variable-speed pump, an isothermal tank, and a flow meter. The gas cooler is a counterflow heat exchanger by cooled water flowing in the annulus. The $CO_2$ flows in the horizontal stainless steel tube. which is 9.53mm in O.D. and 7.75mm in I.D. The gas cooler is 6 [m] in length. which is divided into 12 subsections, respectively. The experimental conditions considered in the study are following range of variables : refrigerant temperature is between 20 and $100^{\circ}C$. mass fluxes ranged from 200 to 400kg/($m^2$.s), average pressure varied from 7.5 to 10.0MPa. The main results were summarized as follows : The friction factors of $CO_2$ in the gas cooler show a relatively good agreement with those predicted by Blasius' correlation. The local heat transfer coefficient in the gas cooler has compared with most of correlations, which are the famous ones for forced convection heat transfer of turbulent flow. The results show that the local heat transfer coefficient of gas cooler agrees well with the correlation by Bringer-Smith except that at the region near pseudo critical temperature. while that at the near pseudo critical temperature is higher than the correlation.

Effect of local heating and cooling on blood flow and heart rate. (서열과 한냉 자극에 대한 반복 국소 노출이 혈류량 및 심박수에 미치는 영향)

  • 박순자
    • Korean Journal of Rural Living Science
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    • v.5 no.1
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    • pp.1-8
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    • 1994
  • This study was conducted to examine whether there is any effect of the local body exposure to hot and cold alternate stress on the blood flow and heart rate. Environmental condition was $20^{\circ}C$ air temperature, 65% relative humidity and 0.2m/s air movement. 22~32 years old four healthy female subjects wore clothes which they felt comfort sitting on a chair. And then their left hand was immersed twice in ($42^{\circ}C$\;and\;15^{\circ}C$ water alternately. Two of the subjects (E-group) were continually exposed to above condition 12 times. While, the other two (C-group) were exposed twice only at the 1st and 12th time of E-group's exposure. The results obtained from this experiment were as follows. \circled1 The initial response of the finger blood flow in I-group to the thermal stress showed more sensitively at the post-training than pre-training. \circled2 Heart .ate was higher in hand immersion at hot water ($42^{\circ}C$) than at cold water ($15^{\circ}C$) \circled3 The pattern of the blood flow of the finger and heart rate was different between E-group and C-group.

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Effects of Seeding during Freezing Procedure on Post-Thaw Viability and Acrosome Integrity of Boar Spermatozoa (돼지정액 동결중 식빙처리가 융해후 정자생존율 및 침체형태에 미치는 영향)

  • Kim Yong-jun;Kim Yong-hwan;Lee Young-jun;Kim Sue-hee;Ji Dong-beom
    • Journal of Veterinary Clinics
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    • v.21 no.4
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    • pp.363-368
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    • 2004
  • To investigate the effects of seeding during freezing procedure on post-thaw viability, motility, and acrosome integrity of boar spermatozoa, semen from 5 Yorkshire boars were collected for this experiment. Raw semen were diluted with Merck I, subsequently added with cooling diluent containing lactose and egg yolk and with freezing diluent containing glycerol. The diluted semen were frozen on the rack in the styrofoam box filled with liquid nitrogen at the distance of 5 cm or I cm above LN2 level. Seeding was performed to only a group of straws frozen at 5 cm away on the surface of LN2. The frozen semen were thawed in $50^{\circ}C$C water and the viability and local motility were analyzed by sperm analysis imaging system. A part of thawed semen was taken for the examination of morphology of apical ridge of the acrosome to compare with the effect of seeding between the seeding-treated and non treated groups. I. Post-thaw viability was considerably higher in seeding-treated sperm than non-seeding group (p<0.01), however, no difference of local motility was obtained among the groups. 2. At three hours after thawing, viability was also higher in seeding-treated group than non-treated group (p<0.05), along with no difference of motility among the groups. 3. Higher normal acrosome integrity was obtained in the seeding-treated sperm than non-treated groups (p<0.01). 4. Between non-seeded groups, higher normal acrosome integrity was obtained in the sperm group frozen at 5cm upper on the surface of LN2 than that frozen at 1cm away (p<0.01). These results indicated that seeding treatment during freezing boar spermatozoa was beneficial to post-thaw viability and normal acrosome integrity.