• 대한영상의학회지
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• 제79권5호
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• pp.264-270
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• 2018

목적: 간기능이 보존된 간세포암 환자에서 간문맥 고혈압이 고주파열치료 후 종양 재발에 미치는 영향을 평가한다. 대상과 방법: 2010년 1월에서 2017년 3월 사이에 Milan criteria 및 Child-Pugh class A를 가진 신규 간세포암 환자 중 본원에서 고주파열치료를 시행한 환자가 본 연구에 포함되었다. 종양 재발에 대한 예측인자를 찾기 위해 Cox proportional hazard model을 이용한 단변량 및 다변량 분석을 수행하였다. 결과: 모두 178명의 환자가 본 연구에 포함되었다. 추적 관찰 기간의 중앙값은 42.8개월이었다. 국소 재발률은 문맥고혈압 여부에 따라 뚜렷한 차이를 유발하지 않았다(p = 0.195). 3년 및 5년 원위부 간내 종양 재발률은 문맥고혈압이 없는 환자의 경우 각각 29.5%와 53.7%, 그리고 문맥고혈압이 있는 환자의 경우 51.9%와 63.6%였으며 두 군 사이의 차이는 통계적으로 유의하였다(p = 0.011). 단변량 및 다변량 분석에서 문맥압항진은 원위부 간내 종양 재발에 대한 독립적인 예측 인자이었다(p = 0.008). 결론: Child-Pugh class A를 가진 간세포암 환자의 경우, 문맥고혈압은 종양 재발에 불량 예후인자로 작용하였다.

• Parasites, Hosts and Diseases
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• 제59권1호
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• pp.47-53
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• 2021

Echinostoma mekongi was reported as a new species in 2020 based on specimens collected from humans in Kratie and Takeo Province, Cambodia. In the present study, its metacercarial stage has been discovered in Filopaludina martensi cambodjensis snails purchased from a local market nearby the Tonle Sap Lake, Pursat Province, Cambodia. The metacercariae were fed orally to an experimental hamster, and adult flukes were recovered at day 20 post-infection. They were morphologically examined using light and scanning electron microscopes and molecularly analyzed by sequencing of their mitochondrial cox1 and nad1 genes. A total of 115 metacercariae (1-8 per snail) were detected in 60 (60.0%) out of 100 Filopaludina snails examined. The metacercariae were round, 174 ㎛ in average diameter (163-190 ㎛ in range), having a thin cyst wall, a head collar armed with 37 collar spines, and characteristic excretory granules. The adult flukes were elongated, ventrally curved, 7.3 (6.4-8.2)×1.4 (1.1-1.7) mm in size, and equipped with 37 collar spines on the head collar (dorsal spines in 2 alternating rows), being consistent with E. mekongi. In phylogenetic analyses, the adult flukes showed 99.0-100% homology based on cox1 sequences and 98.9-99.7% homology based on nad1 sequences with E. mekongi. The results evidenced that F. martensi cambodjensis snails act as the second intermediate host of E. mekongi, and hamsters can be used as a suitable experimental definitive host. As local people favor to eat undercooked snails, these snails seem to be an important source of human infection with E. mekongi in Cambodia.

• 한국보건간호학회지
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• 제11권1호
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• pp.1-13
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• 1997

A systematic health promotion project had been carried out for 3 months (from May 13 to August 4, 1996) in collaboration with nurses of a health center, professors and students of colleges of nursing, and members of senior centers in the community. The outcome was fairly positive : new techniques of public health nurses for health promotion services were developed and those, among the members of senior centers, who had a power of mobility made much progress in their maintenance and enhancement of health through the active use of health equipment. Through this project, we could reconfirm that desirable policies were fundamental tactics for the promotion of health : comprehensive approach to health promotion services, if provided with more or less financial support, would contribute greatly to the activation of public health services by the local administrative organizations.

• 지역사회간호학회지
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• 제14권1호
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• pp.106-119
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• 2003

This study was executed to develop the model of the format of the day care center which supplies the total service on the health care in the day time and social program related with the work and to evaluate the processing courses which was adjusted for 3 years from March 1999 to December 2001 in order to improve the quality of life of the family who experience dementia, dementia prevention, and the old and the burden of daily activities. The processing courses of this business model were evaluated to the confirmation on the health condition, application of the nursing processes, and the precise medical examination, and 20 sorts of social programs. The methods used in this model were the simplified MMSE-K, Ability for ,Daily Life(ADL), Instrumental Activities of Daily Living(IADL), and nursing process, and so on. The execution effects of this model are as follows. 1. It can contribute to the delay in the dementia process of the old people who are related with the dementia and maintenance and improvement of the health by confirming the stopping of the process of the dementia as the objective estimation method while the dementia symptom is maintained as the current condition through the medical and social total services. 2. The reduction of the burden for the daily care of the subject people and their families for the old people who are concerned with the dementia helped to improve the quality of life of the subject people and their family by enabling them to have jobs. 3. It enabled them to positively cope with the demand for the health and nursing of the local residents related to the old people. 4. It enabled them to enhance the recognition for the socialization of the local social organization and residents for the old people. 5. It enabled them to reinforce the related system among the local social organizations, and develop and provide the various social programs which are proper for the old people.

• 보건행정학회지
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• 제23권1호
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• pp.52-58
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• 2013

This study was conducted to investigate the responsiveness and its related factors of public health center for novel influenza A (H1N1) epidemic. The data was collected through a web-based survey conducted during February to April 2011. The 182 respondents were team leaders or persons who were responsible for H1N1-related work at public health centers during the H1N1 prevalence. The related factors affecting the responsiveness were different by urban or rural area. In the level of gu (urban) area, cooperation with the public organizations, preparing its own response plan were the significant factors. But, in the level of si or gun (rural) area, cooperation with private organizations (clinic or pharmacy), physical (facilities, equipments, and medicines), and human infrastructures (public health professions, education and knowledge, and motivation) were more important factors. Therefore, how to cope with H1N1 prevalence in the future should be different by local characteristics. As a result, there are several challenges that public health centers should prepare for the further emerging infectious diseases. First, it is needed to make standard manuals which could strengthen education and training in order to respond appropriately, as well as to prepare enough physical infrastructures for the crisis. Next, the public health center should prepare correct media response and cooperation system with public and private organizations.

• 한국환경보건학회지
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• 제45권6호
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• pp.613-621
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• 2019

Objectives: This study was performed to examine the relationship between health behaviors, living environment, and asthma in adolescents in Korea. Methods: Information on adolescents' characteristics, including demographic factors, health behaviors, and doctor's diagnosis of asthma was obtained from the Korean Youth Risk Behavior Web-based Survey (2015). In total, 68,043 middle and high school students participated. Environmental characteristics, including city park area and outdoor PM₁₀ concentrations in 2015 were obtained from the Korean Statistical Information Service. The adolescents' and environmental characteristics were merged by local information. Multiple logistic regression models were used to investigate the risk factors affecting asthma in adolescents. Results: The prevalence of asthma in adolescents in 2015 was 8.8%. In the multiple logistic regression analysis, adolescents who were male, attended middle school, suffered obesity, experienced tobacco smoking, had physical activity levels of 2 to 4 days, had higher stress levels, and lived in areas with outdoor PM₁₀ concentrations more than 47 ㎍/㎥ were more likely to have asthma, while adolescents who had middle levels of family economic status were less likely to do so. Conclusions: The fact that PM₁₀ concentration can affect asthma is an important point in this study. Risk factors identified in this study could be used as basic data for the prevention and management of asthma in Korea.

• Asian Pacific Journal of Cancer Prevention
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• 제16권10호
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• pp.4383-4386
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• 2015

Background: The C1561T variant of the glutamate carboxypeptidase II (GCPII) gene is critical for natural methylfolylpolyglutamte (methylfolate) absorption, and has been associated with perturbations in folate metabolism and disease susceptibility. However, little is known on C1561T-GCPII as a risk factor for colorectal cancer. Therefore, this study examined whether C1561T-GCPII influences folate metabolism and adenomatous polyp occurrence. Materials and Methods: 164 controls and 38 adenomatous polyp cases were analysed to determine blood folate and plasma homocysteine (Hcy) level, dietary intake of natural methylfolate, synthetic pteroylglutamic acid (PteGlu), vitamin C and C1561T-GCPII genotype. Results: In controls and cases, 7.3 and 18.4 percent of subjects respectively, were found to have the CT genotype, increasing the risk for adenomatous polyp occurrence 2.86 times (95% CI:1.37-8.0, p=0.035). Total dietary folate, methylfolate and PteGlu intake and the level of erythrocyte folate and plasma Hcy did not predict the occurrence of an adenomatous polyp. However, dietary natural vitamin C intake was associated with adenomatous polyp risk within C1561T-GCPII CT genotype subjects (p=0.037). Conclusions: The findings suggest that C1561T-GCPII variation may be associated with risk for adenomatous polyp, and vitamin C may modify risk by interacting with the variant gene, its expression product and/or folate substrates.

• 한국콘텐츠학회논문지
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• 제12권10호
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• pp.178-194
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• 2012

지방의료원의 공공의료 활성화를 위하여 공공의료 본래의 공공성에 대한 고찰과 지방의료원의 현 실태를 파악하고 선행연구 분석과 연구자의 경험을 바탕으로 정책적 요인, 환경적 요인, 재정적 요인, 그리고 자생적 요인이 지방의료원의 활성화에 영향을 미친다고 가정하여 충남 4개 지방의료원을 대상으로 설문을 실시하고 실증 분석을 통해 4가지 요인과 40가지 하위 변수들과의 관계를 밝히고 가설을 검증하였다. 실증적 분석으로서 배경요소를 제시하여 가설 및 연구 모형의 설정, 연구집단 및 분석 방법의 설정, 요인분석 및 신뢰 타당도 분석을 실시하고, 윈도우 7 운영체제의 SPSS 19.0을 분석도구로 지방의료원의 활성화 요인과 변수와의 관계를 조사하였으며, PLS 2.0을 분석도구로 모형분석을 통해 가설을 검증하였다.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제21권2호
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• pp.55-65
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• 2015

Purpose: Korea is increasing in the demand for medical services due to rapid economic growth and population aging in modern society. Thus, the importance has been emphasized for the health promotion in the community and the publicity and substantiality of public health centers. However, the environment is insufficient, compared to required functions and developed services as a urban public health center. The purpose of this study is to analysis the plane type and area composition of public health centers in Busan and to identify the property of their spatial configuration Methods: Eight public health centers in Busan, were classified, which had been selected as a medical tourism city. Subsequently, space requirements were analyzed, facilities were typed, vertical, horizontal spaces were reviewed, and area ratios by business function were calculated. Results: A review of the property of spatial configuration and an analysis of the area ratio revealed the three findings. 1)The horizontal analysis found various types: a single type, a multi-type, a radial type, and a circular type, 2)The vertical analysis showed that since a care function (general practice), and a task function (maternal and child health) were concentrated in lower level spaces, the lobby and core were closed located for providing quick medical services. 3)The analysis of the area ratio in public health centers in terms of their function indicated that each public health center' programs had the greatest influence on the area. Implications: This study attempted to present spatial structural problems and improvements for city public health center by identifying their state and classify their functions and types and by calculating the ratio of their area configuration according to the spatial composition. It was thus aimed to presenting implications in establish public functions and roles by activating business through in connection with the number of municipalities in many ways, such as regional health. medical welfare, etc. to improve the health of local residents, and by providing differentiated programs in accordance with local characteristics.

• Journal of Preventive Medicine and Public Health
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• 제46권3호
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• pp.118-126
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• 2013

We investigated the major trends in health aid financing in the Democratic People's Republic of Korea (DPRK) by identifying the primary donor organizations and examining several data sources to track overall health aid trends. We collected gross disbursements from bilateral donor countries and international organizations toward the DPRK according to specific health sectors by using the Organization for Economic Cooperation and Development creditor reporting system database and the United Nations Office for the Coordination of Humanitarian Affairs financial tracking service database. We analyzed sources of health aid to the DPRK from the Republic of Korea (ROK) using the official records from the ROK's Ministry of Unification. We identified the ROK, United Nations Children's Fund (UNICEF), World Health Organization (WHO), United Nations Population Fund (UNFPA), and The Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM) as the major donor entities not only according to their level of health aid expenditures but also their growing roles within the health sector of the DPRK. We found that health aid from the ROK is comprised of funding from the Inter-Korean Cooperation Fund, private organizations, local governments, and South Korean branches of international organizations such as WHO and UNICEF. We also distinguished medical equipment aid from developmental aid to show that the majority of health aid from the ROK was developmental aid. This study highlights the valuable role of the ROK in the flow of health aid to the DPRK, especially in light of the DPRK's precarious international status. Although global health aid from many international organizations has decreased, organizations such as GFATM and UNFPA continue to maintain their focus on reproductive health and infectious diseases.