• Tuberculosis and Respiratory Diseases
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• v.47 no.6
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• pp.857-862
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• 1999

In contrast to juvenile laryngeal papillomatosis, which occurs most often in children and teenagers and is usually self limited, soliatry papillomas in adults are one of uncommon tumors of airway, and have a higher incidence of cancer. They are caused by the respiratory infection of human papilloma virus(HPV). They could spread to more distal airways and have a tendency of recurrence after limited surgical excision. Recently endoscopic therapies such as Nd-YAG laser, electrocautery, and cryotherapy provide extremely effective treatment modalities. We report a case of solitary tracheal papillomas in a 48 year-old man who presented with cough, scanty hemoptysis, and functional evidence of central airway obstruction. He was successfully treated by a Nd-YAG laser therapy via fiberoptic bronchoscopy under the local anesthesia.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.16 no.2
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• pp.179-185
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• 1994

The Ameloblastoma is a true neoplasm of enamel organ-type tissue histopathologically. Ameloblastoma is recognized as a benign tumor, but its clinical behavior is locally invasive. Therefore treatment of choice is surgical resection rather than conservative enucleation. This is a case report about En-bloc excision of granular ameloblastoma arising from dentigerous cyst in the right mandibular angle area of 50-year male patient. He visited local clinic with chief complaint of facial swelling on the right mandibular angle area. Surgical removal was performed by cyst enucleation and En-bloc excision with preservation of inferior border of mandible. After 1 year, iliac bone graft was done and hyperbaric oxygen therapy was applied. We obtained a good result of bony regeneration without any sign of recurrence.

• Molecules and Cells
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• v.37 no.5
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• pp.412-417
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• 2014

It has been reported that exogenously introduced micro-RNA (exo-miRNA) competes with endogenously expressed miRNAs (endo-miRNAs) in human cells, resulting in a detectable upregulation of mRNAs with endo-miRNA target sites (TSs). However, the detailed mechanisms of the competition between exo- and endo-miRNAs remain uninvestigated. In this study, using 74 microarrays that monitored the whole-transcriptome response after introducing miRNAs or siRNAs into HeLa cells, we systematically examined the derepression of mRNAs with exo- and/or endo-miRNA TSs. We quantitatively assessed the effect of the number of endo-miRNA TSs on the degree of mRNA derepression. As a result, we observed that the number of endo-miRNA TSs was significantly associated with the degree of derepression, supporting that the derepression resulted from the competition between exo- and endo-miRNAs. However, when we examined whether the site proficiency of exo-miRNA TSs could also influence mRNA derepression, to our surprise, we discovered a strong positive correlation. Our analysis indicates that site proficiencies of both exo- and endo-miRNA TSs are important determinants for the degree of mRNA derepression, implying that the derepression of mRNAs in response to exo-miRNA is more complex than that currently perceived. Our observations may lead to a more complete understanding of the detailed mechanisms of the competition between exo- and endo-miRNAs and to a more accurate prediction of miRNA targets. Our analysis also suggests an interesting hypothesis that long 3'-UTRs may function as molecular buffer against gene expression regulation by individual miRNAs.

• Tuberculosis and Respiratory Diseases
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• v.70 no.1
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• pp.79-83
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• 2011

Pulmonary sequestration is a rare anomaly, in which a local area of a lung is supplied separately by an anomalous artery that arises from the aorta or one of its branches. Infection, mainly bacterial, is a major complication of sequestration. We report the case of a 17-year-old male patient, who presented with cough and fever. The contrast-enhanced chest computer tomomgraphy (CT) scans revealed an aberrant artery that originated from the descending thoracic aorta. He underwent a left-lower lobectomy. Macroscopically, the abnormal segment presented as multiple heterogenous cystic and solid lesions, and the cysts were filled with mucoid and pus-like material. Histology showed that the pulmonary parenchyma had been replaced by caseating epitheloid granulomas. The mycobacterial culture of his sputum was positive. On the basis of these results, the diagnosis of tuberculosis was established. The patient was treated with anti-tuberculous medication for 6 months, and 1 year later, his clinical status remained excellent.

• Journal of Communications and Networks
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• v.18 no.4
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• pp.589-599
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• 2016

Most existing resource management problem models arise from the original desire of allocating resources in either a user-centric or network-centric manner. The difference between their objectives is obvious: user-centric methods attempt to optimize the utility of individual users, whereas network-centric models intend to optimize the collective utilities of the entire network. In this paper, from the above two aspects, we analyze the robust power control problem in device-to-device (D2D) communication underlaying cellular networks, where two types of channel uncertainty set (e.g., ellipsoidal and column-wise) are considered. In the user-centric method, we formulate the problem into the form of a Stackelberg game, where the energy efficiency (EE) of each user is the ingredient of utility function. In order to protect the cellular user equipment's (CUE) uplink transmission, we introduce a price based cost function into the objectives of D2D user equipment (DUE). The existence and uniqueness of the game with the influence of channel uncertainty and price are discussed. In the network-centric method, we aim to maximize the collective EE of CUEs and DUEs. We show that by the appropriate mathematical transformation, the network-centric D2D power control problem has the identical local solution to that of a special case of the user-centric problem, where price plays a key role. Numerical results show the performance of the robust power control algorithms in the user-centric and network-centric models.

• Journal of the Korean Institute of Educational Facilities
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• v.21 no.4
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• pp.31-40
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• 2014

The modern day architectural giant, Maki Fumihiko, has lived through both the early and the more recent modernism, Contemporary. In the 1950's he was faithful to the spirit that was founded on the early modernity, Metabolism. In his later years in the 2000's, his style can be distinguished into Neo-Modernism which was based on local influence. The educational system at Washington University and the modern city of Saint Louis carries the continuation of Fumihiko Maki's early and later architectural career. Steinberg Hall and Kemper Art Museum have been built adjacent to each other in an extended period of time. These two projects encompass the changes in the era that has gone through modernism, transformation of an architect's career, and the maturation of the university. Steinberg Hall carries the ideal and the spirit of young Fumihiko Maki, therefore, the basic platform of experimentation of the early Metabolist has been applied. Spatial theory that concentrates on the integration of relations is also evident in this project. In contrast, Kemper Art Museum expresses the work of a 78 year-old veteran from the perspective of Neo-Modernism. This piece focuses on the internal space through the coexistence of a variety of space, and with that it notably interprets the integration of the pieces to the whole as a set theory. The partial change that we see is the evidence of the change in the early and the later modernism, while maintaining the innocence and the spirit of it. This is to highlight the fact that, ultimately, the goal of architecture is to secure the human race's honesty and their freedom expressed through space.

• Archives of Plastic Surgery
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• v.34 no.4
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• pp.520-523
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• 2007

Purpose: Verrucous carcinoma is a rare, low-grade and well-differentiated squamous cell carcinoma, representing as a warty tumor. Estimation of the incidence for cutaneous lesions is not available because they are rare. We describe a case of verrucous carcinoma, a rare type, complication of a chronic pressure ulcer of duration more than 15 years. Methods: A 17-year-old boy presented with a large lesion involving the sacral area, which had been neglected for about 15 years. He had a history of surgical extirpation 2 years ago, but not cured. Examination revealed a cauliflower-like mass arising from an irregularly oval-shaped tumor which was $6.0{\times}4.5cm$ in size with signs of infection and ulcer. The lesion involved the sacrococcygeal area, spreading to both medial gluteal regions. The perianal skin did not appear to be directly affected. Results: A preoperative punch biopsy revealed a extremely well differentiated verrucous carcinoma. There were positive results in immunohistochemistry in the items of p53, p63, Ki-67. An 'en-bloc' excision of the tumor with the clinically normal surrounding tissue was carried out. Reconstruction was achieved by local regional flap. Histopathological findings of the excised area fully confirmed the preoperative biopsy report. It remained free of recurrence for a period of about 8 months. Conclusion: We believe that in patients with buttock involvement, regardless of the extent of such tumors, surgical therapy should be considered as the first-choice of treatment as reconstruction can be performed without excessive impairment for the patient.

• Journal of Chest Surgery
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• v.31 no.5
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• pp.540-543
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• 1998

A patient with post-pneumonectomy empyema was treated sucessfully by modification of Clagett's operation after closure of bronchopleural fistula using a transsternal, transpericardial approach. His primary disease was pulmonary tuberculosis, and he had a past history of left upper lobe lobectomy 34 year ago. Recently recurred pulmonary tuberculosis with aspergilloma in the remaining left lung, empyema with bronchopleural fistula had developed on the post-operative 4th day after completion pneumonectomy. Closed thoracostomy was done at the lowest point of the left pleural cavity immediately. The pleural cavity was irrigated with small amount of normal saline through pigtail catheter. The 2nd operation was done by closure of bronchopleural fistula using a stapler through transsternal, transpericardial approach, and then the pleural space was irrigated with normal saline with Tobramycin which shows sensitivity to isolated organism from pleural cavity. After negative conversion of pleural fluid culture, we performed modified Clagett's operation under local anesthesia. The patient had no evidence of recurrence of empyema and discharged from hospital after 10 days of the 3rd procedure.

• Radiation Oncology Journal
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• v.3 no.1
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• pp.35-39
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• 1985

The details of 5 patients with exramedullary plasmacytoma of the head and neck were reviewed for the period from 1970 to 1984. All patients were presented with localized disease at the time of diagnosis. Out of 5 patients the one treated with surgery alone developed local recurrence and disseminated disease. He died at 3 years and 6 months. Rest of the four were alive with no evidence of the disease. Two patients were treated with radiation therapy alone while other two were treated with surgery and postoperative radiation therapy. Curative radiation therapy is recommanded after the diagnosis is established by biopsy examination.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.518-521
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• 2005

We performed the mechanical test for obtaining properties of femoral head. Tested sample was male and 35 years old. We measured bone mineral density by dual X-ray absorption method(DEXA). Results of DEXA, he has normal condition of bone density. His BMD $1.159g/cm^2$ and T-Score is 1.6. Tested femurs were harvested by surgical method from donated cadaver. We made 9 specimens in femoral head, 8 specimens in neck used by diamond core drill. Then we performed compressive test in saline solution at $38^{\circ}C$. We obtained results that elastic modulus of femoral head was 0.439GPa, neck was 0.459GPa. Compressive strength of femoral head was 7.441 MPa, neck was 7.095MPa. There was no significant difference of mechanical properties between left and right femoral head & neck. Invested local properties of femoral head have more strength superior and anterior side, femoral neck has more strength in superior and inferior side but other side except for superior has more weakness along the lateral side.