• Title/Summary/Keyword: Loading Rate Effect

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THE EFFECT OF AUTOLOGOUS PLATELET-RICH PLASMA (PRP) ON BONE FORMATION AROUND DENTAL IMPLANT IN THE RABBIT: A HISTOMOR-PHOMETRIC AND REMOVAL TORQUE STUDY

  • Yi Yang-Jin;Yang Jae-Ho;Lee Sun-Hyung;Kim Yung-Soo;Kwon Sang-Ho
    • The Journal of Korean Academy of Prosthodontics
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    • v.39 no.6
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    • pp.659-681
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    • 2001
  • Platelet-rich plasma(PRP) has been known to increase the rate and degree of bone formation by virtue of growth factors in concentrated platelets. Although its great healing effect on bone defect or pre-implantation site preparation in conjunction with bone substitute has been reported, the effect associated with implant is unknown. The purpose of this study was to investigate the effect of PRP on rapid osseointegration of endosseous dental implants in the rabbit tibiae. Twenty two adult female New Zealand white rabbits, weighing approximately 2.7-3.3kg, were used for this study. Twelve of the 22 animals were used for histomorphometric analysis and ten of the 22 were for removal torque test. Each animal received two implants in each tibia (two treated with PRP and two as control) and was given fluorochrome intramuscularly. For histomorphometric analysis, rabbits were divided into four groups according to the healing period. At 1 week, 2 weeks, 4 weeks and 8 weeks postoperatively, each three animals were sacrificed serially and the amount and rate of bone formation around dental implant were examined on the undecalcified sections under fluorescent microscope, polarized microscope and light microscope connected to a personal computer equipped with image analysis system. For removal torque test, rabbits were divided into two groups and removal torque tests were performed at 4 weeks, 10 weeks after implant placement. In total, 88 screw shaped, commercially pure titanium implants (Neoplant, Neobiotech, Seoul, Korea) were used in this study. Labeling pattern reflected differences of two groups in bone formation rate at each period. Histomorphometrically, PRP group showed significantly higher bone volume within threads compared to control group at 2 weeks ($70.30{\pm}4.96%$ vs. $50.68{\pm}6.33%$; P < .01) and 4 weeks ($82.59{\pm}5.94%$ vs. $72.94{\pm}4.57%$; P < .05 ). PRP group at 1, 2 and 4 weeks revealed similar degree of bone volume formation comparable to control group at 2, 4 and 8 weeks, respectively. On the other hand, while PRP group showed higher bone-implant contact ($47.37{\pm}8.09%$) than control group ($33.16{\pm}13.47%$) at 2 weeks, there were no significant differences between PRP group and control group for any experimental period. Removal torque values also showed no significant differences between PRP group and control group at any experimental period (P > .05). These findings imply that PRP could induce rapid, more bone formation around implant during early healing period and get faster secondary stability for reducing healing period, though it has not induced bone maturation enough to resist functional loading.

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A Study on the Resistance and Crack Propagation of ITO/PET Sheet with 20 nm Thick ITO Film (20 nm 두께의 ITO층이 코팅된 ITO/PET Sheet의 저항 및 균열형성 특성 연구)

  • Kim, Jin-Yeol;Hong, Sun-Ig
    • Journal of the Korean Ceramic Society
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    • v.46 no.1
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    • pp.86-93
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    • 2009
  • The crack formation and the resistance of ITO film on PET substrate with a thickness of 20 nm were investigated as a function of strain. The onset strain for the increase of resistance increased with increasing strain rate, suggesting the crack initiation is dependent on the strain rate. Electrical resistance increased at the strain of 1.6% at the strain rates below $10^{-4}/sec$ while it increased at ${\sim}2%$ at the strain rates above $10^{-3}/sec$. The critical strain at which the cracks were formed is close to the proportional limit. Upon loading, the initial cracks perpendicular to the tensile axis were observed and propagated the whole sample width with increasing strain. The spacing between horizontal cracks is thought to be determined by the fracture strength and the interfacial strength between ITO and PET. The crack density increased with increasing strain. However, the effect of the strain rate on the crack density was less pronounced in ITO/PET with 20 nm ITO thickness than ITO/PET with 125 nm ITO thickness, the strength of ITO film is thought to increase as the thickness on ITO film decreases. The absence of cracks on ITO film at a strain as close as 1.5% can be attributed to the compressive residual stress of ITO film which was developed during cooling after the coating process. The higher critical strain for the onset of the resistance increase and the crack initiation of ITO/PET with a thinner ITO film (20 nm) can be linked with the higher strength of the thinner ITO film.

Anaerobic Digestion of Agricultural Wastes and 1ts Benefits (농산폐기물(農産廢棄物)의 메탄발효(醱酵)와 그 이점(利點))

  • Park, Young-Dae
    • Applied Biological Chemistry
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    • v.27
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    • pp.3-17
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    • 1984
  • Anaerobic digestion has recently attracted all over the world and Korea also shows no exception. The major benefits of anaerobic digestion are energy production, water pollution control, pathogen reduction and effective manure production. In Korea it was recognized in late sixties that there was a positive need to find alternative energy for farmers household. The main traditional energy sources in rural area were crop residues and forestry products. Therefore Office of Rural Development through its Rural Guidance Bureau disseminated about 29,000 household biogas units from 1969 to 1975 to provide cooking fuel for farmers household and to improve the mode of farmers living standards. The units were welcomed by farmers at that time. Now, however, most of them are not using due to a number of reasons associated with cold winter and some techno-economical problems (in those day, fossil fuel was quite expensive to compare with other prices and since then farmers income was quickly increased). The author studied on bag type household biogas plant to solve some technical problems of existing household biogas plants, but this also has little appeal for the farmers. From 1977 author studied on village scale biogas plant with two pilot plants. From the viewpoint of energy production, COD removal, kill rate of pathogen and fertilizer value, the results obtained from the experiments were quite promising, but the construction cost of the village scale biogas plant was too high for the farmers in Korea. To find most suitable biogas plant for farmers in Korea through the simplifying the biogas digester, the author developed batch-load biogas plant. By feeding coarse crop residues and manures, total solids concentrations of the batch-load biogas plant are about 28 percent which is much higher than continous digester of 5-8 percent. The batch-load biogas plant was welcomed by many farmers in Korea when it was reported on TV and newspapers. The plant was disseminated 154 units in 1982, 766 units in 1983 and 812 units in 1984 as a promissing project. Besides these biogas plant experiments, studies were also conducted 1) to determine gas production rate with agricultural wastes, 2) to evaluate the effect of loading rate, dilution, retention time on biogas production, 3) to project the amount of potencial energy from agricultural wastes.

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Acoustical Similarity for Small Cooling Fans Revisited (소형 송풍기 소음의 음향학적 상사성에 관한 연구)

  • 김용철;진성훈;이승배
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 1995.04a
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    • pp.196-201
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    • 1995
  • The broadband and discrete sources of sound in small cooling fans of propeller type and centrifugal type were investigated to understand the turbulent vortex structures from many bladed fans using ANSI test plenum for small air-moving devices (AMDs). The noise measurement method uses the plenum as a test apparatus to determine the acoustic source spectral density function at each operating conditions similar to real engineering applications based on acoustic similarity laws. The characteristics of fans including the head rise vs. volumetric flow rate performance were measured using a performance test facility. The sound power spectrum is decomposed into two non-dimensional functions: an acoustic source spectral distribution function F(St,.phi.) and an acoustic system response function G(He,.phi.) where St, He, and .phi. are the Strouhal number, the Helmholtz number, and the volumetric flow rate coefficient, respectively. The autospectra of radiated noise measurements for the fan operating at several volumetric flow rates,.phi., are analyzed using acoustical similarity. The rotating stall in the small propeller fan with a bell-mouth guided is mainly due to a leading edge separation. It creates a blockage in the passage and the reduction in the flow rate. The sound power levels with respect to the rotational speeds were measured to reveal the mechanisms of stall and/or surge for different loading conditions and geometries, for example, fans installed with a impinging plate. Lee and Meecham (1993) studied the effect of the large-scale motions like impinging normally on a flat plate using Large-Eddy Simulation(LES) and Lighthill's analogy.[ASME Winter Annual Meeting 1993, 93-WA/NCA-22]. The dipole and quadrupole sources in the fans tested are shown closely related to the vortex structures involved using cross-correlations of the hot-wire and microphone signals.

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Thermoelastic effect on inter-laminar embedded delamination characteristics in Spar Wingskin Joints made with laminated FRP composites

  • Mishra, P.K.;Pradhan, A.K.;Pandit, M.K.;Panda, S.K.
    • Steel and Composite Structures
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    • v.35 no.3
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    • pp.439-447
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    • 2020
  • This paper presents two sets of full three-dimensional thermoelastic finite element analyses of superimposed thermo-mechanically loaded Spar Wingskin Joints made with laminated Graphite Fiber Reinforced Plastic composites. The study emphasizes the influence of residual thermal stresses and material anisotropy on the inter-laminar delamination behavior of the joint structure. The delamination has been pre-embedded at the most likely location, i.e., in resin layer between the top and next ply of the fiber reinforced plastic laminated wingskin and near the spar overlap end. Multi-Point Constraint finite elements have been made use of at the vicinity of the delamination fronts. This helps in simulating the growth of the embedded delamination at both ends. The inter-laminar thermoelastic peel and shear stresses responsible for causing delamination damage due to a combined thermal and a static loading have been evaluated. Strain energy release rate components corresponding to the Mode I (opening), Mode II (sliding) and Mode III (tearing) of delamination are determined using the principle of Virtual Crack Closure Technique. These are seen to be different and non-self-similar at the two fronts of the embedded delamination. Residual stresses developed due to the thermoelastic anisotropy of the laminae are found to strongly influence the delamination onset and propagation characteristics, which have been reflected by the asymmetries in the nature of energy release rate plots and their significant variation along the delamination front.

The Effects of the Initial Crack Length and Fiber Orientation on the Interlaminar Delamination of the CFRP/GFRP Hybrid Laminate (초기 균열길이 및 섬유방향이 CFRP/GFRP 하이브리드 적층재의 층간 파괴에 미치는 영향)

  • Kwon, Oh-Heon;Kwon, Woo-Deok;Kang, Ji-Woong
    • Journal of the Korean Society of Safety
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    • v.28 no.1
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    • pp.12-17
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    • 2013
  • Considering the wind power system and the rotor blades which are composed of much technology, the wind power blade would be the most dangerous part because it revolves at high speed and weighs about dozens of tons, if the accident happens. Therefore, the light weight composite materials have been replacing as substitutional materials. The object of this study is to examine the delamination and damage for CFRP/GFRP hybrid composite that is used for strength improvement of a wind power blade. The influence of the initial crack length and fiber orientation for the interlaminar delamination was exposed for the blade safety. Plain woven CFRP instead of GFRP was inserted into the layer of the box spar for improving the strength and blade life. DCB(Double Cantilever Beam) specimen was used for evaluating fracture toughness and damage evaluation of interlaminar delamination. The material used in the experiment is a commercial material known as CF 3327 EPC in plain woven carbon prepreg(Hankuk Carbon Co.) and UD glass fiber prepreg(Hyundai Fiber Co.). From the results, crack growth rate is not so different according to the variation of the initial crack length. Mode I interlamainar fracture toughness of fiber direction $0^{\circ}$ is higher than that of $45^{\circ}$. Interlaminar fracture has an effect on fiber direction and K decreased with lower value according to increasing initial crack length. Also energy release rate fracture toughness was evaluated because CFRP/GFRP hybrid composite with a different thickness is under the mixed mode loading condition. The interlaminar fracture was almost governed by mode I fracture even though the mixed mode.

Study on the Vitrification of Human Blastocysts I. Effect of Cryo-Solution and Development Stage on the Survival Rate of Vitrified Blastocysts (인간 포배기 배아의 초자화 동결에 관한 연구 I. 동결액과 발생단계가 초자화 동결한 포배가 배아의 생존율에 미치는 영향)

  • 김수희;이상원;이주희;강상민;이승민;이성구;윤혜균;윤산현;박세필
    • Journal of Embryo Transfer
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    • v.14 no.3
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    • pp.145-153
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    • 1999
  • This study was conducted to investigate the effects of vitrification solution and developmental stage on the survival rate of vitrified-thawed human blastocyst embryos. Human blastocyst embryos were cryopreserved by vitrification using EFS and GE solution, and their survival rates were examined after thawing and further culture. EFS solution was consisted of 40% ethylene glycol, 18% Ficoll 70 and 0.3M sucrose. GE solution was consisted of 25% glycerol and 25% ethylene glycol. Embryos were exposed to EFS and GE solution by 2 steps and 3 steps, respectively, and plunged into liquid nitrogen after loading into 0.25ml plastic straws. Blastocysts were classified into 4 groups in accordance with their developmental stage: into 1) EEB, 2) MEB and 3) EdB, of blastocysts developed on day 5, and 4) 6d-Bla(the blastocysts which formed on day 6). The blastocysts at each stage were vitrified by GE solution and cryopreserved in LN2. After thawing them, we examined their survival rates, respectively. The resulted of this study were as follows: 1. The survival rate of blastocysts vitrified by GE solution was 64.4%, significantly higher than that (5.7%) vitrified by EFS solution (P<0.001). 2. When the blastocysts were vitrified by GE solution according to each developmental stage, the survival rates of EEB, MEB, EdB and 6d-Bla were 65.9%, 65.9%, 73.2% and 58.1%, respectively. In conclusion, the cryopreservation of human blastocysts by vitrification is likely to have a marked advantage in terms of cost, work and time as compared to the conventional slow freezing in IVF-ET programs.

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Influence of ITO Thickness on the Deformation and Cracking Behaviors of ITO/PET Sheets (ITO층의 두께에 따른 ITO/PET sheet의 변형거동 및 균열 형성 거동)

  • Kim, Jin-Yeol;Hong, Sun-Ig
    • Korean Journal of Materials Research
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    • v.19 no.1
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    • pp.1-6
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    • 2009
  • In this study, the stress-strain response and the cracking behaviors of ITO film on a PET substrate are investigated. The cracking behaviors of ITO thin films deposited on a thermoplastic semi-crystalline polymer developed for flexible display applications was investigated by means of tensile experiments equipped with an electrical measurement apparatus and an in-situ optical microscope. Electrical resistance increased gradually in the elastic-to-plastic transition region of the stress strain curves and cracks formed. Numerous cracks were found in this region, and the increase of the resistance was linked to the cracking of ITO thin films. Upon loading, the initial cracks perpendicular to the tensile axis were observed at about 1% of the total strain. They propagated to the entire sample width as the strain increased. The spacing between the horizontal cracks is thought to be determined by the fracture strength and the thickness of the ITO film as well as by the interfacial strength between the ITO and PET. The effect of the strain rate on the cracking behavior was also investigated. The crack density increased as the strain increased. The spacing between the horizontal cracks (perpendicular to the stress axis) increased as the strain rate decreased. The increase of the crack density as the strain rate decreased can be attributed to the higher fraction of the plastic strain to the total strain at a given total strain. The higher critical strain for the onset of the increase in the resistance and the crack initiation of the ITO/PET with a thinner ITO film (300 ohms/sq.) suggests a higher strength of the thinner ITO film.

The Effects of Physical Aging of PSF/AS4 Laminate on Fatigue (PSF/AS4 복합재료의 가속노화가 피로강도에 미치는 영향)

  • Kim, Hyung-Won
    • Composites Research
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    • v.19 no.4
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    • pp.1-6
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    • 2006
  • The effects of aging on fatigue of PSF/AS4 laminates tvas studied using the new energy release rate analysis. The analysis by the variational mechanics has been useful in providing fracture mechanics interpretation of matrix microcracking in cross-ply laminates. This paper describes the changes of the critical energy release rate ${\Delta}Gmc$(microcracking toughness) about the variation of the aging period during fatigue loading. The master plot by modified Pans-law gives a characterization of a material system's resistance to microcrack formation. PSF/AS4 $[0/902]_s$ laminates were aged at four different temperatures based on the glass transition temperature for 60 days. At all temperatures, the toughness decreased with aging time. The decrease of the toughness at higher temperature was faster than at lower temperature. To assess the effects of aging on fatigue, the unaged laminates were compared with the laminates which were aged for 60 days at $170^{\circ}C$ near $180^{\circ}C\;T_g$. The slope of dD/dN versus A 6u, of the aged laminates was lower than that of the unaged laminates. There was a significant shift of the aged data to formation of microcracks at the lower values of ${\Delta}G_m$.

Numerical study for the optimum grouting design of subsea tunnels (해저터널의 그라우팅 최적 설계를 위한 수치해석적 연구)

  • Joo, Eun-Jung;Kim, Yong-Kye;Shin, Jong-Ho;Kwon, Oh-Yeob
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.12 no.5
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    • pp.349-358
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    • 2010
  • In the long-term, most tunnels suffer from the increase in ground water inflow and in pore water pressure on the lining. To reduce such hydraulic effect, generally grouting methods are adopted. In this paper effective grouting design is proposed based on numerical simulation. To investigate the optimal grouting layout, factors such as relative permeability, grouting thickness, and distance from the lining are considered. The results are analysed in terms of pore water pressure, inflow rate, and earth pressure. It is revealed that the pore water pressure has increased with a decrease in grout permeability, an increase in grouting thickness and an increase in grouting distance. Meanwhile the inflow rate has decreased with a decrease in grout permeability and is inversely proportional to grouting thickness. Effective grouting design guideline are proposed based on this study.