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The Effect of Behavioral Response and Arthritic Tissue on Swimming Exercise and Achyranthes Radix Extracts in Type II Collagen-Induced Arthritic Rat (제 2형 콜라겐 유도 관절염에서 수중운동과 우슬추출물이 행동반응과 관절 조직에 미치는 영향)

  • Choi, Ki-Bok;Kim, Gye-Yeop;Nam, Ki-Won;Kim, Kyong-Yoon;Kim, Eun-Jung
    • The Journal of Korean Physical Therapy
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    • v.21 no.2
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    • pp.117-124
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    • 2009
  • Purpose: This study examined the effects of swimming exercise and Achyranthes Radix extracts on the inflammatory and behavioral responses in type II collagen-induced arthritic rats for 28 days. Methods: Sprague-Dawley rats were allocated randomly to one of the following four groups: only type II collageninduced (group Ⅰ), application of swimming exercise after type II collagen-induced (group II), application of Achyranthes Radix ointment after type II collagen-induced (group III), application of swimming exercise and Achyranthes Radix ointment after type II collagen-induced (group IV). Arthritis was established in SD rats by an intradermal injection of Chick type II collagen plus incomplete Freund's adjuvant at the base of the tail of the animals. The swimming exercise program consisted of a 25 min swimming session/day with a load corresponding to 5.5% of the weight bearing, three days/week for four weeks. The Achyranthes Radix ointment (0.1g) was applied twice a day for five days. The changes in behavior, H & E stain, and cyclooxygenase-2 (COX-2) level in the knee joint were assessed. Results: The gross and histological examination, after RA induction showed reddening, edema and erythema. The H & E stain revealed the destruction of articular cartilage, bony erosion and the infiltration of inflammatory cells after RA induction. The mechanical allodynia test results were significantly higher in group I than in groups II, III and IV (p<0.01). The immunohistochemistrical response of COX-2 in the knee joint showed that groups II, III, IV had a lower response effect than group I. Conclusion: Swimming exercise training and Achyranthes Radix ointment decreased the inflammatory responses and enhanced the behavioral responses in the arthritic rats.

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A study on the development of tunnel soundness evaluation system using artificial neural network (인공신경망을 이용한 터널 건전도 평가시스템 개발)

  • 김현우;김영근;이희근
    • Tunnel and Underground Space
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    • v.9 no.1
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    • pp.48-55
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    • 1999
  • One of the major roles of concrete lining is the supplementary support of ground load. Therefore, if there are cracks or deformation found in the lining, the causes should be carefully examined. Tunnel Soundness Evaluation System (DW-TSES) was developed to meet such requirements. Main facility of the system was intended to find the probable causes on the basis of the apparent changes in lining and the environmental conditions. It also includes facilities for evaluating the soundness of a tunnel and indicating the method for repair or reinforcement. The characteristic feature of damages is used for reasoning in case of deterioration and leakage, and artificial neural network is used in external pressure. This process depends on the results of the case analyses and FDM, which have a collection of the typical features of different types of damages as well as the unusual changes caused by the external pressure. The comparison of the outputs of this system with those of expert's diagnoses draws the following conclusions. 1) Artificial neural network was a suitable tool to find to causes of damages by external pressure. 2) The environmental conditions improved the accuracy in reasoning. 3) The result of finding causes and evaluating soundness was helpful to suggest effective methods concerning tunnel maintenance.

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Design and Evaluation of a Microcomputer-based Vacuum Drying System for Shiitake Mushrooms (마이크로컴퓨터 시스템을 이용한 표고버섯의 감압건조에 대한 연구)

  • Choi, Jae-Yong;Kim, Kong-Hwan;Chun, Jae-Kun
    • Korean Journal of Food Science and Technology
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    • v.19 no.6
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    • pp.550-555
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    • 1987
  • Strain gauges attached on the Bourdon tube and load cell were used as the sensors for measuring the vacuum pressure in drying chamber and the weight loss of Shiitake mushrooms respectively. The vacuum drying system was interfaced further with the Bear II microcomputer. The interface devices used were built with such IC chips as MC 6821, ADC 0809, SN 74244 and SN 7424. The relationship between readings of vacuum gauge (P, mmHg) and digital outputs (D) from the microcomputer was represented by P =3.08 D-13.4875(r=0.9999). The weights of drying sample (W) were also related with the digital outputs (D) by W=0.4076 D-6.4762 (r=0.9999). During the vacuum drying of Shiitake mushrooms. the data on pressure and weight were recorded at regular intervals using an acquisition program on the microcomputer system. The Page model was fitted well to the drying data of Shiitake mushrooms. resulting in the following empirical equations : $(M-M_e)/(M_o-M_e)=\exp(-0.1569t^{1.0048})$ at 400 mm Hg up to 14 hours and $(M-M_e)/(M_o-M_e)=\exp(-0.1385_t^{1.2688})$ at 600 mm Hg up to 8 hours.

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Evaluation of Vertical Bearing Capacity for Bucket and Shallow Foundations Installed in Sand (사질토 지반에 설치된 버킷기초 및 얕은기초의 수직지지력 산정)

  • Park, Jeongseon;Park, Duhee;Jee, Sunghyun;Kim, Dongjoon
    • Journal of the Korean GEO-environmental Society
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    • v.16 no.9
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    • pp.33-41
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    • 2015
  • The vertical bearing capacity of a bucket foundation installed in sand can be calculated as sum of the skin friction and end bearing capacity. However, the current design equations are not considering the non-associated flow characteristics of sand and the reduction in the skin friction and increase in the end bearing capacity when the vertical load is applied. In this study, we perform two-dimensional axisymmetric finite element analyses following non-associated flow rule and calculate the vertical bearing capacity of circular bucket foundation of various sizes installed in sand of different friction angles. After calculating the skin friction and end bearing force at the ultimate state, design equations are derived for each. The skin friction of bucket foundation is shown significantly small compared to the end bearing capacity. Considering the difference with the available design equation for piles, it is recommended that the equation for piles is used for the bucket foundation. A new shape-depth factor ($s_q{\cdot}d_q$) for bucket foundation is recommended which also accounts for the increment of the end bearing capacity due to skin friction. Additionally, the shape and depth factor of embedded foundation proposed from the associated flow rule can overestimate the bearing capacity in sand, so it is more adequate to use the shape-depth factor proposed in this study.

A STUDY OF VON-MISES YIELD STRENGTH AFTER MANDIBULAR SAGITTAL SPLIT RAMUS OSTEOTOMY (하악지시상분할골절단술 시행 후 von-Miese 항복강도에 대한 유한요소법적 연구)

  • Yoon, Ok-Byung;Kim, Yeo-Gab
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.28 no.3
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    • pp.196-204
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    • 2002
  • For the study of its stability when the screw has been fixed after sagittal split ramus osteotomy(SSRO) of the mandible, the methods of screw arrangement are classified into two types, triangular and straight. The angles of screws to the bone surface are classified as perpendicular arrangements, the $60^{\circ}$ anterioinferior screw, known as triangular, and the most posterior screw, called straight arrangement, thus there are four types. The finite element method model has been made by using a three dimensional calculator and a supercomputer. The load directions are to the anterior teeth, premolar region, and molar region, and the bite force is 1 Kgf to each region. The distribution of stress, the von-Mises yield strength, and safety of margin refer to the total sum of transformed energy have been studied by comparison with each other. The following conclusion has been researched : 1. When shear stress is compared, in the triangular arrangement in the form of "ㄱ", the anterosuperior screw is seen at contributing to the support of the bone fragment. In the straight arrangement, substantial stress is seen to be concentrated on the most posterior angled screw. 2. When the von-Mises yield strength is compared, it seemed that the stress concentration on the angled anteroinferior screw is higher, it shows a higher possibility of fracture than any other screw. In the straight arrangement, stress appeared to be concentrated on the most posteriorly angled screw. 3. When the safety margins of the transfomed energy are compared, the energy conduction is much greater in the case of the angled screw than in the case of the perpendicular screw. The triangular arrangement in the form of "ㄱ" shows a superior clinical sign to that of the straight arrangement. Judging from the above results, when the screw fixation is made after SSRO in practical clinical cases, two screws should be inserted in the superior border of mandibular ramus and a third screw of mandibular inferior border should be inserted in the form of triangular. All screws on the bony surface should be placed perpendicularly-$90^{\circ}$ angles apparently best promote bony support and stability.

Effects of oropharyngeal taste stimuli in the restoration of the fasting-induced activation of the HPA axis in rats (백서에서 금식으로 인한 스트레스 대응축 활성화의 회복조절기전에서 구강인두로부터 입수되는 다양한 맛 자극의 효과)

  • Yoo, Sang-Bae;Lee, Jong-Ho;Ryu, Vitaly;Jahng, Jeong-Won
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.37 no.3
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    • pp.195-204
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    • 2011
  • Introduction: This study examined the regulatory mechanism underlying the meal-induced changes in the hypothalamic-pituitary-adrenal gland (HPA) axis activity. Materials and Methods: Male Sprague-Dawley rats (250-300 g) were hired for two different experiments as follows; 1) rats received either 8% sucrose or 0.2% saccharin ad libitum after 48 h of food deprivation with the gastric fistula closed (real feeding) or opened (sham feeding). 2). rats received 5 ml of intra-oral infusion with 0.2% saccharin or distilled water after 48 h of food deprivation. One hour after food access, all rats were sacrificed by a transcardiac perfusion with 4% paraformaldehyde. The brains were processed for c-Fos immunohistochemistry and the cardiac blood was collected for the plasma corticosterone assay. Results: Real feedings with sucrose or saccharin and sham feeding saccharin but not sucrose, following food deprivation decreased the plasma corticosterone level. c-Fos expression in the nucleus tractus of solitarius (NTS) of the fasted rats was increased by the consumption of sucrose but not saccharin, regardless of the feeding method. On the other hand, the consumption of sucrose or saccharin with real feeding but not the sham, induced c-Fos expression in the paraventricular nucleus (PVN) of the fasted rats. The intra-oral infusion with saccharin or water decreased the plasma corticosterone level of the fasted rats. Intra-oral water infusion increased c-Fos expression in both the PVN and NTS, but saccharin only in the NTS in the fasted rats. Conclusion: Neither restoration of the fasting-induced elevation of plasma corticosterone nor the activation of neurons in the PVN and NTS after refeeding requires the palatability of food or the post-ingestive satiety and caloric load. In addition, neuronal activation in the hypothalamic PVN may not be an implication in the restoration of the fasting-induced elevation of the plasma corticosterone by oropharyngeal stimuli of palatable food.

CLINICAL AND RADIOGRAPHICAL EVALUATION OF IMPLANT-SUPPORTED FIXED PARTIAL PROSTHESES (임플랜트 지지 고정성 국소의치의 임상적, 방사선학적 평가)

  • Seo Ji-Young;Shim June-Sung;Lee Jae-Hoon;Lee Keun-Woo
    • The Journal of Korean Academy of Prosthodontics
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    • v.44 no.4
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    • pp.394-404
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    • 2006
  • Statement of problem: A conventional 3-unit fixed partial denture design with a pontic between two retainers is the most commonly used. However in cases where the mental nerve is in close proximity to the second premolar, a cantilever design can be considered. As such, logical and scientific evidence is lacking for the number and position of implants to be placed for partially edentulous patients, and no clear-cut set of treatment principles currently exist. Purpose : The purpose of this study was to evaluate prognosis of implant-supported fixed partial dentures and to compare changes in bone level which may rise due to the different factors. Material and method : The present study examined radiographical marginal bone loss in patients treated with implant-supported fixed partial dentures (87 prostheses supported by 227 implants) and evaluated the influence of the span of the pontic, type of the opposing dentition. Clinical complications were studied using a retrospective method. Within the limitation of this study. the following result were drawn Result, 1. Seven of a total of 227 implants restored with fixed prostheses failed, resulting in a 96.9% success rate. 2. Complications encountered during recall appointments included dissolution of temporary luting agent (17 cases), porcelain fracture (8 cases), loosened screws (5 cases), gingival recession (4 cases), and gingival enlargement (1 case). 3. Marginal bone loss, 1 year after prosthesis placement, was significant(P<0.05) in the group that underwent bone grafting, however no difference in annual resorption rate was observed afterwards. 4. Marginal bono loss, 1 year post-placement, was greater in cantilever-type prostheses than in centric pontic protheses (P<0.05). 5. Marginal bone loss was more pronounced in posterior regions compared to anterior regions (P<0.05). 6. The degree of marginal bone loss was proportional to the length of the pontic (P<0.05). Conclusion: The success rate of implant-supported fixed partial dentures, including marginal bone loss, was satisfactory in the present study. Factors influencing marginal bone loss included whether bone graft was performed, location of the pontic (s), location of the surgical area in the arch pontic span. Long-term evaluation is necessary for implant-supported fixed partial dentures, as are further studies on the relationship between functional load and the number of implants to be placed.

FLEXION EFFECTS OF HEAT TREATMENT AND POST-SOLDRING OF CERAMO-METAL FIXED PARTIAL DENTURE FRAMEWORKS USING HOLOGRAPHIC INTERFEROMETRY (Holographic Interferometry를 이용한 하악 구치부 도재소부 전장관용 금속 구조물의 굴곡성향에 대한 연구)

  • Choi, Jin-Woong;Woo, Yi-Hyung;Choi, Boo-Byung
    • The Journal of Korean Academy of Prosthodontics
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    • v.34 no.4
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    • pp.869-902
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    • 1996
  • Flexion of a metal/ceramic fixed partial denture(EPD) frameworks under function can cause fracture of porcelain or deterioration of the cement seal. This study evaluated the flexion characteristics of three-unit mandibular FPD frameworks, repacing the second pre-molar under compressive load(200g, 400g). Testing was accompished with real-time holographic interferometry, using 6 porcelain fused-to metal frameworks. Tested alloys were non-precious alloy(Heracles, Holland), semi-precious alloy(Degudent U, Germany) and precious alloy(Degudent H, Germany). Changes of the fringe patterns according to the heat treatment(porcelain firing cycle), various loads(200g, 400g), occlusal forms(occlusal porcelain veneering, facial porcelain veneering), various alloys and post-soldering units were compared. Dental study model(Nissan dental products, Inc. D51DP-500A, Japan) and six 3-unit metal/ceramic fixed partial denture frameworks were used as experimental materials. 36 holograms were taken on fixed dental study model by using the 10mW He-Ne laser and real-time holographic interferometry. On the basis of this study, the following conclusions can be drawn : 1. In the frameworks for facial porcelain veneering, the semi-precious alloy framework was least deformed and precious alloy framework, non-precious alloy framework orderly before heat treatment, and the deformation was not shown great difference among three alloys after heat treatment and post-soldering. 2. In the frameworks for occlusal porcelain veneering, the precious alloy framework was greatest deformed and the deformation was not difference between semi-precious alloy framework and non-precious alloy framework before, after heat treatment, and the deformation was not shown great difference among three alloys after post soldering. 3. In the non-precious alloy frameworks for facial porcelain veneering and occlusal porcelain veneering, the deformation was greatly decreased after heat treatment and conversely increased after post-soldering. 4. In the semi-precious alloy framework for facial porcelain veneering, the deformation was not detectable after heat treatment and increased after post-solder. And in the frame-work for occlusal porcelain veneering, the deformation was slightly decreased after heat treatment and increased after post-soldering. 5. In the precious alloy framework for facial porcelain veneering, the deformation was greatly decreased after heat treatment and increased after post-soldering, And in the framework for occlusal porcelain veneering, the deformation was greatly decreased after heat treatment and decreased after post-soldering.

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A STUDY ON THE SHEAR BOND STRENGTH OF LIGHT CURED GLASS IONOMER CEMENTS TO CONTAMINATED DENTIN (상아질 표면상태에 따른 광중합형 글래스아이오노머 시멘트의 전단결합강도에 관한 연구)

  • Kim, Kyoung-Hwa;Park, Sang-Jin
    • Restorative Dentistry and Endodontics
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    • v.22 no.2
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    • pp.609-621
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    • 1997
  • The purpose of this study was to evaluate the shear bond strength of three light-cured glass ionomer cements to blood contaminated bovine dentin. The materials used in this study were Fuji II LC, Dyract and Variglass VLC. The dentin conditioners were 10% polyacrylic acid, 10% maleic acid and 10% phosphoric acid. 180 lower anterior bovine teeth were selected in this study. The teeth were embedded in acrylic resin and were grounded with 320 to 600 grit silicon carbide paper to create a flat dentin surface. The teeth were divided into SIX groups. The experimental procedures in six groups were as follows; Group l(GF) : Samples bonded to dentin surface with Fuji II LC after 10% polyacrylic acid treatment. Group 2(BGF) : Samples bonded to dentin surface with Fuji II LC after 10% polyacrylic acid treatment and blood contamination. Group 3(MD) : Samples bonded to dentin surface with Dyract after 10% maleic acid treatment. Group 4(BMD) : Samples bonded to dentin surface with Dyract after 10% maleic acid treatment and blood contamination. Group 5(PV) : Samples bonded to dentin surface with Variglass VLC after 10% phosphoric acid treatment. Group 6(BPV) : Samples bonded-to dentin surface with Variglass VLC after 10% phosphoric acid treatment and blood contamination. Group 1,3 and 5 were classified into the control groups, while group 2,4 and 6 were classified into the experimental groups. Each group contained 30 samples. After 24 hours water storage at $37^{\circ}C$, all smples were subjected to a shear load to fracture at a cross head speed of 1.0 mm/min with Instron universal testing machine(No. 4467). Debonded surfaces were observed under Scanning Electron Microscope(Hitachi S-2300) at 20kvp. The data were evaluated statistically at the 95% confidence level with Student's t-test. The following results obtained; 1. Shear bond strengths were higher in the control groups(1,3,5 group) than in the experimental groups(2,4,6 group). 2. The shear bond strength of group 5(PV) was the highest in the control groups, and the group 5 was significantly higher than the group l(GF) on the shear bond strength. 3. The group 4(BMD) was the highest on the shear bond strength, and the group 2(BGF) was the lowest in the experimental groups. The group 4(BMD) and 6(BPV) showed a significant difference with the group 2 on the shear bond strength. 4. All the groups showed an adhesive-cohesive failure. except the group 2(BGF) showing adhesive failure.

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Long-Term Behavior of Square CFT Columns with Diaphragm (격막이 설치된 각형 CFT 기둥의 장기거동에 관한 연구)

  • Kwon Seung-Hee;Kim Tae-Hwan;Kim Yun-Yong;Kim Jin-keun
    • Journal of the Korea Concrete Institute
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    • v.17 no.6 s.90
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    • pp.1025-1032
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    • 2005
  • This paper presents experimental and analytical studies on long-term behavior of square CFT columns with diaphragm. In order to investigate the effect of the diaphragm on the long~term behavior, experiments for six specimens with two diaphragms and three different column length, and three-dimensional finite element analysis for each specimen have been performed. The finite element models considering the interface behavior between the steel tube and the inner concrete were verified from comparison of the test results with the analysis results. From the test and the analysis results, the following conclusions were obtained. The confinement effect created by the diaphragm does not depends on column length and influences only a part of the whole column that is from the end to the depth which is the same to the width of the column. The shortening of the column with diaphragm which covers more than a half of the cross sectional area of the inner concrete is the same as that of the column under a load applied on the steel tube and the entire section of the inner concrete.