• Journal of Computational Design and Engineering
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• v.2 no.1
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• pp.16-25
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• 2015

Since construction projects are large and complex, it is especially important to provide concurrent construction process to BIM models with construction automation. In particular, the schematic Quantity Take-Off (QTO) estimation on the BIM models is a strategy, which can be used to assist decision making in just minutes, because 70-80% of construction costs are determined by designers' decisions in the early design stage. This paper suggests a QTO process and a QTO prototype system within the building frame of Open BIM to improve the low reliability of estimation in the early design stage. The research consists of the following four steps: (1) analyzing Level of Detail (LOD) at the early design stage to apply to the QTO process and system, (2) BIM modeling for Open BIM based QTO, (3) checking the quality of the BIM model based on the checklist for applying to QTO and improving constructability, and (4) developing and verifying a QTO prototype system. The proposed QTO system is useful for improving the reliability of schematic estimation through decreasing risk factors and shortening time required.

• Korean Journal of Crystallography
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• v.4 no.1
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• pp.6-10
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• 1993

11 β ,17 β -dihydroxy-9a-fluoro-l7a-methyl androst-4-en-3-one (Fluoxymesterone), CgoH29 FO,, orthorhombic, P2,2,2,, a=13.468(5) A, b= 19.554 (2)A, c=6.578(9)A, a=b=r=90˚, A (CuKa)=1.5406 A , Dm=1.289cm-3, Dc=1.299cm-3 and Z=4 at T=298k. The structure was solved by direct method using seminvariants of ggg Parity group and refined by the full-matrix least-square method, resulting model with reliability factor R=0.069 for 1098 unique reflection over 3σ . Ring A is an 1β-2a-half chair, 5 ring has a highly symmetrical chair conformation, C ring is in a distorted chair conformation and D ring is a 13aenveLope conformation. In the crystal structure, the molecules are packed with a hydrogen bond of 011-H23‥‥03(0.5+x, 1.5-y, 1.0-z) [1.94(9) A of H‥‥0.2.786(9)A of 0‥‥0 and 165(8) ˚ of

• Biomolecules & Therapeutics
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• v.22 no.1
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• pp.27-34
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• 2014

Curcumin is naturally occurring polyphenolic compound found in turmeric and has many pharmacological activities. The present study was undertaken to evaluate anti-allergic inflammatory activity of curcumin, and to investigate its inhibitory mechanisms in immunoglobulin E (IgE)/Ag-induced mouse bone marrow-derived mast cells (BMMCs) and in a mouse model of IgE/Ag-mediated passive systemic anaphylaxis (PSA). Curcumin inhibited cyclooxygenase-2 (COX-2) dependent prostaglandin $D_2$ ($PGD_2$) and 5-lipoxygenase (5-LO) dependent leukotriene $C_4$ ($LTC_4$) generation dose-dependently in BMMCs. To probe the mechanism involved, we assessed the effects of curcumin on the phosphorylation of Syk and its downstream signal molecules. Curcumin inhibited intracellular $Ca^{2+}$ influx via phospholipase $C{\gamma}1$ ($PLC{\gamma}1$) activation and the phosphorylation of mitogen-activated protein kinases (MAPKs) and the nuclear factor-${\kappa}B$ (NF-${\kappa}B$) pathway. Furthermore, the oral administration of curcumin significantly attenuated IgE/Ag-induced PSA, as determined by serum $LTC_4$, $PGD_2$, and histamine levels. Taken together, this study shows that curcumin offers a basis for drug development for the treatment of allergic inflammatory diseases.

• Asian Journal for Public Opinion Research
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• v.9 no.2
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• pp.188-211
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• 2021

Decreasing response rates to traditional survey methods, like face-to-face and telephone interviews, have led survey practitioners around the world to seek new ways of conducting surveys in recent years." The COVID-19 pandemic exacerbated this problem because it made conducting face-to-face interviews even more difficult than before. For example, it made conducting face-to-face surveys infeasible in 2020 in South Korea, and so the Korean Academic Multimode Open Survey (KAMOS) was unable to conduct a planned face-to-face survey to recruit new panel members. The entire 8,514-member panel, established via two-stage probability-based sampling from 2016 to 2019, was invited to take three online/telephone surveys in 2020. Of these panel members, 1,352 responded to at least one survey in 2020. To test to what extent the panel remained representative of the adult South Korean population, we compared the two groups of panel members: those who responded to at least one survey in 2020 and those who did not. After weighting both groups on the basis of age, sex, and geographical area, we analyzed their responses to some of the questions that were asked during multiple rounds of the face-to-face panel-recruiting interviews. Using Cohen's d for survey items that could be analyzed numerically and Cramér's V for categorical items, we were able to conclude that the respondents to the 2020 surveys were equivalent to the non-respondents in terms of both demographics and in the answers they originally gave to substantive questions on a variety of topics related to social science or public opinion research, including questions about quality of life, societal issue, and politics (Cohen's d items <0.2, 95% CI; Cramér's V items <0.1, 95% CI). This analysis may provide a model for others who wish to test the continued representativeness of their panel or who would like to use a different survey mode or change some other aspect of their methodology and test whether it is equivalent to their former methodology. Our success in building a panel that retained its representativeness may be useful to those in other countries where face-to-face surveys had previously been the norm but are becoming increasingly difficult to conduct.

• Journal of Environmental Policy
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• v.11 no.3
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• pp.49-65
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• 2012

Road traffic noise is closely related to road traffic environment, including traffic volumes by type and travel speed. In this study, we stated some issues and analyzed the relationships between road traffic noise and traffic flow characteristics. First, in attempt to find the answer to the question "When does the loudest traffic noise occur?" we reviewed the issue in the terms of traffic flow. As a result of analyzing level of service through Korea Highway Traffic Noise model, the actual maximum noise occurred in level of service D rather than level of service E, on the capacity state. It shows that maximum noise would be most likely to occur right before and after the peak hours. Second, this paper was looking for the method of a more easy and accurate traffic speed estimation to predict traffic noise. This paper proposed sketch planning techniques of speed-volume curve by level of service on Korea Highway Capacity Manual. As a result of trend line modeling, it was judged that quadratic form is a suitable function, and coefficient of determination ($R^2$) was higher than 0.96, respectively.

• Journal of Korean Tunnelling and Underground Space Association
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• v.24 no.2
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• pp.153-170
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• 2022

Waterjet has been comprehensively used in urban areas owing to a suitable technique for cutting concrete and rock, and low noise and vibration. Recently, the abrasive waterjet technique has been adopted and applied by the Korea Atomic Energy Research Institute to demolish concrete plugging without disturbing and damaging In-situ Demonstration of Engineered Barrier System in the disposal research tunnel. In this study, the use of abrasive waterjet in the tunnel was evaluated for practical applicability and the existing cutting model was compared with the experimental results. As a variable for waterjet cutting, multi-cutting, water flow rate, abrasive flow rate, and standoff distance were selected for the diversity of analysis. As regarding the practical application, the waterjet facilitated path selection for cutting the concrete plugging and prevented additional disturbances in the periphery. The pump's noise at idling was 64.9 dB which is satisfied with the noise regulatory standard, but it exceeded the standard at ejection to air and target concrete because the experiment was performed in the tunnel space. The experimental result showed that the error between the predicted and measured cutting volume was 12~13% for the first cut and 16% for second cut. The standoff distance had a significant influence on the cutting depth and width, and the error tended to decrease with decrement of standoff distance.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.31 no.5
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• pp.215-226
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• 2018

In this paper, to estimate the dynamic behavior of a submerged floating tunnel(SFT) by underwater explosion(UE), the SFT is modeled and analyzed by the explicit structural analysis package LS-DYNA. The section of SFT near to explosion point is modeled to shell and solid elements using elasto-plasticity material model for concrete tubular section and steel lining. And the other parts of the SFT are modeled to elastic beam elements. Also, mooring lines are modeled as tension-only cable elements. Total mass of SFT is including an added mass by hydrodynamic effect. The buoyancy on the SFT is considered in its initial condition using a dynamic relaxation method. The accuracy and the feasibility of the analysis model aree verified by the results of series of free field analysis for UE. And buoyancy ratio(B/W) of SFT, the distance between SFT and an explosion point and the arrangement of mooring line aree considered as main parameters of the explosion analysis. As results of the explosion analysis, the dynamic responses such as the dent deformation by the shock pressure are responded less as more distance between SFT and an explosion point. However, the mooring angle of the diagonal mooring system can not affect the responses such as the horizontal displacement of SFT by the shock pressure.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.20 no.4
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• pp.106-117
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• 2021

In Korea, interest in truck platooning is increasing because most cargo transportation is done by road. Truck platooning is the operation of two or more trucks in a row to form one platoon, which can increase road capacity and improve fuel efficiency. In this study, to analyze the effect of truck platooning on traffic flow, scenarios were created according to traffic conditions and truck platooning operating conditions. In order to understand the effect of the truck platooning operating conditions, correlation analysis was conducted with the average travel speed, the number of lane change disturbance, and the number of disturbance in the entry/exit section. As a result, the number of trucks in the platoon, the spacing of trucks in the platoon, and the spacing between platoons were found to have an effect on the average speed and the number of lane change disturbance In addition, the truck platooning ratio was found to have a strong correlation with the average travel speed and the number of lane change disturbance regardless of the LOS.