• 한국임상수의학회지
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• 제38권2호
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• pp.85-88
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• 2021

A 9-year-old, intact female Shih-tzu dog presented with a three-week history of anorexia, lethargy, and weight loss. Abdominal radiography revealed a mass in the right cranial quadrant of the abdomen that was displacing the right kidney caudally. Ultrasonography showed a large, irregular, heterogeneous hepatic mass and a small amount of peritoneal fluid. On computed tomography (CT), a large hypoattenuating mass with heterogeneous contrast enhancement occupied the right lateral lobe, and parts of the right medial and caudate lobes of the liver. There was no evidence of regional lymph node or pulmonary metastasis. Lobectomy of the right medial, right lateral and caudate liver lobes was performed, however, the patient did not recover from surgery. Hepatoblastoma was confirmed by histological examination. Hepatoblastoma is rare in dogs, and this is the first report describing CT imaging of hepatoblastoma in a dog.

• Journal of Yeungnam Medical Science
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• 제12권2호
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• pp.400-404
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• 1995

국소 결절성 과형성은 섬유성 격막에 의해 나누어지는 간세포와 Kupffer 세포의 결절로 이루어진 양성 종괴이다. 방사선학적으로 다른 종괴와 유사한 소견을 보이나 그 예후와 치료는 달라 감별이 요구된다. 저자들이 경험한 증례는 조영 후 영상을 조영전기영상과 조영후기영상으로 분리함으로써 종괴의 혈류형태를 관찰할 수 있는 급속조영 CT를 설시하여 감별진단에 도움을 받을 수 있었고 병리조직학적으로 국소 결절성 과형성으로 확인된, 급속조영 CT 설시 후 국내에서 보고되는 최초의 증례이다.

• 한국방사선학회논문지
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• 제16권7호
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• pp.943-952
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• 2022

지방간 진단을 위한 검사로, 최근 초음파 검사와 혈액검사를 동시에 병행하여 시행하고 있다. 특히 혈액검사 중 hs-CRP의 경우, 심혈관 질환 뿐 아닌, 인체의 다양한 부위에 대한 염증 수치를 나타내는 지표로 사용되고 있다. 따라서 본 연구를 통해 비알콜성 지방간 정도에 따른 대사증후군 구성 요소와 간 기능 및 hs-CRP수치 등의 연관성을 분석해 지방간 진단 임상 지표로 활용하고자 연구를 진행하였다. 2021년 3월~2021년 8월 한국 건강관리 협회 광주 전남지부에서 복부 초음파 검사를 실시하여 비알콜 지방간이 관찰된 환자 중 대사증후군 구성요소와 간 기능 및 hs-CRP 검사를 모두 실시한 만 20세 이상, 남녀 총 1,139명의 피검사 수치 데이터를 대상으로 하였다. 남녀 전체를 대상으로 분석한 경우 경도 지방간 환자의 간 검사 수치가 AST 30 U/L, ALT 32.1 U/L hs-CRP 0.14 mg/dL로 중등도 지방간 환자의 혈액 검사 수치 AST 38 U/L, ALT 47.6 U/L, 54.9 IU/L, hs-CRP 0.22 mg/dL보다 낮았으며 통계적으로 유의했다(P<0.001). hs-CRP 검사의 경우 경도 지방간 환자보다 중등도 지방간 환자에서 통계적으로 유의할 만큼 높은 수치 차이를 나타낸 것으로 보아 hs-CRP 검사가 지방간 예방과 관리를 위한 임상적 데이터로도 활용될 수 있을 것으로 사료된다.

• 대한핵의학회지
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• 제16권2호
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• pp.71-80
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• 1982

In the present communication, the results will be reported on a clinical study of how well scintigraphic visualization of the hepatobiliary elements and several commonly used clinical liver function tests correlate each other in various diseases oft hepatobiliary system. The demonstrability of the biliary tract, gallbladder (GB) and duodenum was rather closely paralleled to serum bilirubin level and less closely to alkaline phosphatase and rather poorly to SGOT and SGPT. The biliary tree could not be visualized scintigraphically when bilirubin exceeded 10.5mg/dl. The usefulness of Tc-99m EHIDA [N-(2,6-diethylacetanilido) iminodiacetic acid, made by Amersham, England] hepatobiliary scintigraphy (Tc EHIDA HBS) in settling diagnostic controversy and ambiguity raised by oral cholecystography, intravenous cholangiography and ultrasonography in many hepatobiliary diseases is well known. The purpose of this investigation was to semiquantitatively evaluate the scintigraphic demonstrability of the hepatobiliary tract, GB and duodenum following intravenous injection of Tc-99m EHIDA in normal subjects and in patients with a disturbed liver function from various hepatobiliary diseases. The hepatobiliary scintigraphy was performed in 10 normal subjects and 39 patients with various hepatobiliary diseases (Table 1) at the Dept. of Radiology, St. Mary's Hospital Catholic Medical College, Seoul, Korea during 2 years period from September 1979. Scintigraphic examination was started at end of 3 minutes after intravenous injection of Tc-99m EHIDA in the amount of $50{\mu}Ci/kg$ and was continued until after 30 minutes at 5 minutes interval. The imaging was usually terminated when the tracer could be seen in the duodenum. Late scintigrams were obatained at 1 1/2, 3, 4 and 6 hours when reeded. Scintigrams were analyzed in terms of promptness and clarity of visualization of the biliary tree, GB and duodenum and demonstrability of these anatomical landmarks was correlated with the values of liver function tests. The demonstrability of the common hepatic duct, common bile duct, GB and duodenum was closely paralleled to the level of serum bilirubin when it is less than 10.5 mg/dl as shown in figure 1. However when the bilirubin exceeded 10.5 mg/dl the time of visualization between protracted reaching a flat curve or plateau around 10.5 mg/dl. The biliary tract could not be visualized when the bilirubin was higher than 10.5 mg/dl. The correlability between scintigraphic demonstration and serum alkaline phosphatase was less strong and between scintigraphic demonstration and SGOT and SGPT was rather poor. The present clinical study confirmed the usefulness and limitation of Tc-99m EHIDA hepatobiliary scintigraphy in visulizing and diagnosing the biliary system and duodenum when radiogrpahy and ultrasonography failed to provide useful informations. Scintigraphy was very helpful in the diagnosis of neonatal hepatitis, biliary atresia, cholecystitis and extrahepatic biliary obstruction. The hepatobiliary system and duodenum were visualized when serum bilirubin level was less than 10.5 mg/dl, SGOT 135 units, SGPT 114 units and alkaline phosphatase 52.2 KAU.

• Journal of Chest Surgery
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• 제29권7호
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• pp.785-788
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• 1996

간농양에 이은 급성 화농성 심낭염은 드문 질환이다. 급성화농성 심낭염은 적절한 치료가 이루어지지 않을 경우 사망율이 매우 높은 위 험한 질환이다. 환자는 32세 남자 환자로 발열, 오한, 상복부동통 및 호흡곤란을 주소로 응급실로 내원 하였다. 단순 흉부사진상 심비대의 소견을 보이고 있었으며, 복부초음파상 간좌엽에 종괴가 있었다. 심초음파상 임박 심장압진의 소견을 보이고 있었다. 응급으로 횡격막천공을 통해 간농양을 배농시켰고 심낭절개술을 시 행하였다. 심낭은 비후되어 두꺼워져 있었고 600m1의 악취가 나는 농액과 괴사조직들이 배액되었다. 섬유소응괴(abrinclot)가심근과유착이 있었다 조직학적 검사상심낭은급성 염증소견과 미세한 괴사 소견을 보이고 있었고, 균배양검사상 혈액과 배농액 에서 모두 Escherichia coli가 나왔다. 환자는 항생제 치료 받고 4주만에 퇴원 했고 심초음파상 약간의 교착성 심낭염의 소견을 보였다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제4권1호
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• pp.113-119
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• 2001

소아에서 간의 간엽 과오종은 주로 복부팽만을 주소로 내원하여 대부분 2세 이내에 발견되며, 비교적 크기가 큰 낭종의 소견을 보이는 것으로 알려져 있다. 저자들은 담도 폐쇄증으로 Kasai 수술받은 8개월 여아에서 복부 초음파 검사상 작은 기질성 종괴를 우연히 발견하여 병리학적으로 확진된 간엽과오종 1례를 보고하는 바이다.

• 한국임상수의학회지
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• 제35권4호
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• pp.146-149
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• 2018

A 7-year-old, castrated, male Maltese dog presented with hyporexia and depression for 3 days. Elevated serum amylase, lipase activities, and liver enzyme values were found upon blood examination. An abdominal mass was seen on radiographs caudal to the gastric body in the left middle abdomen. In the left middle abdomen, abdominal ultrasonography also revealed a massive, irregularly marginated, heterogeneous mass of unknown origin, and in the right cranial abdomen, heterogeneously hypoechoic pancreatic tissue and hyperechoic change of adjacent mesenteric fat were observed. Contrast-enhanced computed tomography showed an irregular contour of the left pancreatic limb as well as heterogeneously enhanced parenchyma. A low-attenuating peripancreatic fluid collection with a thin and irregular wall was also seen. Based on these findings, an atypical pancreatic abscess with necrotizing pancreatitis which manifested as walled-off necrosis was suspected. The mass was excised, and the pancreatic abscess was confirmed by histopathologic examination. No complications were found in the patient after two months of follow-up examination.

• 대한수의학회지
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• 제37권3호
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• pp.661-668
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• 1997

Portal blood flow was measured with pulsed doppler ultrasound in thirty normal dogs. In normal dogs, the average portal blood flow velocity was $17.03{\pm}1.75cm/sec$ and the average portal blood flow was $41.59{\pm}10.10ml/min/kg$. The incident angle between the doppler beam and the portal vein averaged $65^{\circ}$. The average portal vein sectional area was $0.41{\pm}0.14cm^2$. The Congestion index was $0.0245{\pm}0.0081cm{\cdot}sec$. Conclusively, the spectral doppler ultrasonography was quick, non-invasive and simple diagnostic method in circulatory disorders of liver.

• 한국임상수의학회지
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• 제37권5호
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• pp.286-291
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• 2020

A 15-year-old castrated male Persian (Case 1), an 1.5-year-old castrated male Bengal (Case 2), and an 1.5-year-old spayed female Russian Blue (Case 3) cats were presented with iris-color change and suspicious anterior chamber mass. Complete ophthalmic examination revealed a vascularized or blood tinted mass filling with anterior chamber accompanied by rubeosis iridis, dyscoria, keratic precipitates, and severe aqueous flare. Ocular ultrasonography showed an iridociliary mass with blood flow signal in Case 1. Abdominal ultrasonography also revealed suspicious metastatic involvements of liver and spleen in this cat. Case 2 and 3 were suspected of being infected with feline infectious peritonitis. Topical antibiotic/steroid combinations were prescribed to control the uveitis in all 3 cases, although enucleation was initially considered for palliative pain management in Case 1. Anterior chamber mass had almost completely disappeared after topical medications and uveitis has been successfully managed, remaining in sight, even though ocular hypertension developed 1 month later in Case 1.

• 한국임상수의학회지
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• 제37권6호
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• pp.355-359
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• 2020

Contrast-enhanced ultrasonography (CEUS) has been applied to evaluate parenchymal organs in human and veterinary medicine. However, to our knowledge, there is no report on the identification of active bleeding and the bleeding site in veterinary clinical patients. Herein, we describe the use of CEUS in two cases of abdominal bleeding caused by ruptured lesions with malignant abdominal tumors. One dog had a splenic hemangiosarcoma, which had metastasized to the liver; the other dog had hepatic cell carcinomas in the left hepatic lobe, which were lobectomized, and another nodule was identified in the right hepatic lobe. Immediately after the rupture of these oncogenic lesions was suspected, CEUS was performed to identify the bleeding sites. The active bleeding sites were confirmed by hyperechoic pooling signs in the arterial phase, and extravasation could be observed within the defects showing hypoechoic perfusions in the delayed phase of the CEUS. Microbubbles were also observed in the ascites; thus, CEUS could detect the presence of hemorrhage and accurately identify the bleeding site. Collectively, the study findings suggest the usefulness of CEUS in emergent situations as it enables rapid and noninvasive evaluation of bleeding points in case of active bleeding in dogs.