• Journal of Microbiology and Biotechnology
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• v.16 no.4
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• pp.619-622
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• 2006

Biotransformation is a good tool to synthesize regioselective compounds. It could be performed with diverse sources of genes, and microorganisms provide a myriad of gene sources for biotransformation. We were interested in modification of flavonoids, and therefore, we cloned a putative O-methyltransferase from Bacillus cereus, BcOMT-2. It has a 668-bp open reading frame that encodes a 24.6-kDa protein. In order to investigate the modification reaction mediated by BcOMT-2, it was expressed in E. coli as a His-tag fusion protein and purified to homogeneity. Several substrates such as naringenin, luteolin, kaempferol, and quercetin were tested and reaction products were analyzed by thin layer chromatography (TLC) and high performance liquid chromatography (HPLC). BcOMT-2 could transfer a methyl group to substrates that have a 3' functional hydroxyl group, such as luteolin and quercetin. Comparison of the HPLC retention time and UV spectrum of the quercetin reaction product with corresponding authentic 3'-methylated and 4'-methylated compounds showed that the methylation position was at either the 3'-hydroxyl or 4'-hydroxyl group. Thus, BcOMT-2 transfers a methyl group either to the 3'-hydroxyl or 4'-hydroxyl group of flavonoids when both hydroxyl groups are available. Among several flavonoids that contain a 3'- and 4'-hydroxyl group, fisetin was the best substrate for the BcOMT-2.

• Journal of the Korean Society of Safety
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• v.8 no.4
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• pp.207-212
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• 1993

Numerical inverstigation of heat transfer in phase-change energy storage devices was performed in order to aid In the design process for a finned Phase-Change Material( PCM). A simplified model based on a quasi-linear, transient, thin fin equation, which predicts the fraction of melted phase-change material, and the shape of liquid-solid interface as a function of time, is used. The model is solved by using Finite Volume Method(FVM), and the numerical results have showed good agreement with experimental data.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.33 no.3
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• pp.78-85
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• 2005

The purpose of the study was to establish the design procedure and develop the program for designing regenerative cooling system. To obtain the design parameter necessary for the realization of regenerative cooling system, water-cooled regenerative cooling system was designed from suggested procedure. To compare experimental results with a present method of analytically predicting the heat transfer loads, $250kg_{f}$ experimental LRE with water-cooled regenerative cooling system was investigated. Based on the investigation, the good correction between the predicted and measured data was verified. Developed design program can be used to designing Kerosene- cooled regenerative cooling system. The basic experimental data and correlations obtained in this study for 250kgf experimental LRE with water-cooled regenerative cooling system can be directly applicable to the real LRE.

• Proceedings of the KSRS Conference
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• 2003.11a
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• pp.28-30
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• 2003

Hot Spring Law of Taiwan was passed in legislative assembly on 3 June 2003. Hot springs would become one of the most important natural resources for recreation purposes. Both public and private sectors will invest large amount of capital in this area in the near future. The value of remote sensing technology is to give a critical tool for observing the landscape to find out mega-scaled geological structures, which may not be able to be found by conventional approaches. The occurrences of the hot springs in Taiwan are mostly in metamorphic and sedimentary rocks , other than in volcanic environments. Local geothermal anomaly or heat of springs transfer by liquid convection other than conduction or radiation. The deeply -seated fractures of hard rocks are the conduit of the convection of hot water, which could be as deep as 3000 meters in a hypothetical model of Taiwan. Clues to find outcrops of hot spring can be obtained by a structure-controlled model deduced by geological lineaments observed by satellite images and stereoscopic interpretation of aerial photographs. A case study conducted in Eastern Taiwan will be demonstrated.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2005.05a
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• pp.123-126
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• 2005

Eye Glass Display (EGD) with microdisplay to realize the virtual display can make the large screen, so virtual image has been developed by using microdisplay panel. This paper shows study of low cost lens design and simulation for microdisplay system with 0.6"LCoS panel. Lens design optimized consider to spherical aberration, astigmatism, distortion, and chromatic aberration. Code V is used and it designed an aspheric lens about exit pupil 6mm, eye relief 20mm and 35 degree of field of view (FOV). With the application this aspheric lens to liquid crystal on silicon (LCOS) type's microdisplay, virtual image showed 50 inch at 2m. One side of the aspheric lens was constituted from diffractive optical element (DOE) for the improvement in a performance. It had less than 2.5% of distortion value and modulation transfer function in axial had 20% of resolution with 32 lp/mm spatial frequency. The optical system is suitable for display of 15.6 mm-diagonal with SVGA.

• Journal of Mechanical Science and Technology
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• v.19 no.6
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• pp.1329-1337
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• 2005

The OLED (Organic Light Emitting Diodes) display recently used for the information indicating device has many advantages over the LCD (Liquid Crystal Display), and its demand will be increased highly. The linear cell should be designed carefully considering the uniformity of thin film on the substrate. Its design needs to compute the temperature field analytically because the uniformity for the thin film thickness depends on the temperature distribution of the source (organic material). In the present study, the design of the linear cell will be modified or improved on the basis of the temperature profiles obtained for the simplified linear cell. The temperature distributions are numerically calculated through the STAR-CD program, and the grids are generated by means of the ICEM CFD program. As the results of the simplified linear cell, the temperature deviation was shown in the parabolic form among the both ends and the center of the source. In order to reduce the temperature deviation, the configuration of the rectangular ends of the crucible was modified to the circular type. In consequence, the uniform temperature is maintained in the range of about 90 percent length of the source. It is expected that the present methods and results on the temperature analysis can be very useful to manufacture the vapor deposition device.

• Journal of Radiation Industry
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• v.10 no.4
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• pp.199-204
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• 2016

The dependence of cell survival on exposure dose and the duration of the liquid-holding recovery (LHR) was obtained for diploid yeast cells irradiated with ionizing radiation of different linear energy transfer (LET) and recovering from radiation damage without and with various concentrations of cisplatin - the most widely used anticancer drug. The ability of yeast cells to recover from radiation damage was less effective after cell exposure to high-LET radiation, when cells were irradiated without drug. The increase in cisplatin concentration resulted in the disappearance of this difference whereas the fraction of irreversible damage was permanently enlarged independently of radiation quality. The probability of cell recovery was shown to be constant for various conditions of irradiation and recovery. A new mechanism of cisplatin action was suggested according with which the inhibition of cell recovery after exposure to ionizing radiations was completely explained by the production of irreversible damage.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2004.10a
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• pp.178-183
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• 2004

Thermal stratification phenomena in the liquid oxygen tank of launch vehicle is caused by heat influx from ambient and non-equilibrium heat and mass transfer in the cryogenic tank. The thermal stratification study is needed for designing vent system, tank insulation, pump inlet. In this paper by investigating buoyancy driven boundary layer flow by side wall heating, one dimensional analysis of thermal stratification is peformed. thermal gradient is described with time.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.18 no.5
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• pp.418-425
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• 2006

An AHX (Accumulator Heat exchanger) consists of a commercial accumulator and an inner heat exchanger located inside of the accumulator. The AHX is used in multi air-conditioners to assure that liquid-phase refrigerant enters into the expansion device. This purpose is achieved by heat transfer between the refrigerant leaving the evaporator and the refrigerant leaving the condenser. In this study, the effects of AHX on the performance of a refrigeration system using R-22 were measured and the test results were analyzed. The operating characteristics of the refrigeration system with the AHX are considerably different from those without the AHX. Therefore, it is required to determine optimum refrigerant charge and optimum operating conditions when the AHX is used in the refrigeration system having a constant flow-area expansion device such as capillary tube.

• Nuclear Engineering and Technology
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• v.53 no.9
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• pp.2909-2917
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• 2021

Following the launch of Rare Isotope Science Project in December 2011, a heavy ion accelerator complex in South Korea, named RAON, has since been designed. It includes a muon facility for muon spin rotation, relaxation, and resonance. The facility will be provided with 600 MeV and 100 kW (one-fourth of the maximum power) proton beam. In this study, the graphite target in RAON was designed to have a rotating disk shape and was cooled by radiative heat transfer. This cool-down process has the following advantages: a low-temperature gradient in the target and the absence of a liquid coolant cooling system. Monte Carlo simulations and ANSYS calculations were performed to optimize the target system in a thermally stable condition when the 100 kW proton beam collided with the target. A comparison between the simulation and experimental data was also included in the design process to obtain reliable results. The final design of the target system will be completed within 2020, and its manufacturing is in progress. The manufactured target system will be installed at the RAON in the Sindong area near Daejeon-city in 2021 to carry out verification experiments.