• Korean Journal of Cleft Lip And Palate
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• v.11 no.2
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• pp.65-70
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• 2008

Cleft lip and/or palate are common birth defects in humans and the causes including multiple genetic and environmental factors are complex. Combinations of genetic, biochemical, and embryological approaches in the laboratory mice are used to investigate the molecular mechanisms underlying normal craniofacial development and the congenital craniofacial malformations including cleft lip and/or palate. Both forward and reverse genetic approaches are used. The forward genetic approach involves identification of causative genes and molecular pathways disrupted by uncharacterized mutations that cause craniofacial malformations including cleft lip and/or cleft palate. The reverse genetic approach involves generation and analyses of mice carrying null or conditional mutations using the Cre-loxP mediated gene targeting techniques.

• Archives of Craniofacial Surgery
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• v.25 no.2
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• pp.62-70
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• 2024

Background: The management of cleft lip and palate aims at improving the patient's aesthetic and functional outcomes. Delaying primary repair can disrupt the patient's functional status. Long-term follow-up is essential to evaluate the need for secondary repair or revision surgery. This article presents the epidemiology of cleft lip and palate, including comprehensive patient characteristics, the extent of delay, and secondary repair at our institutional center, the Bandung Cleft Lip and Palate Center, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia. Methods: This retrospective study aimed to determine the epidemiology and recurrence rates of cleft lip and palate at the Bandung Cleft Lip and Palate Center, Indonesia, from January 2007 to December 2021. The inclusion criteria were patients diagnosed with cleft lip and/or palate. Procedures such as labioplasty, palatoplasty, secondary lip and nasal repair, and alveolar bone grafting were performed, and data on recurrence were available. Results: In total, there were 3,618 patients with cleft lip and palate, with an age range of 12 months to 67 years. The mean age was 4.33 years, and the median age was 1.35 years. Males predominated over females in all cleft types (60.4%), and the cleft lip was on the left side in 1,677 patients (46.4%). Most cases were unilateral (2,531; 70.0%) and complete (2,349; 64.9%), and involved a diagnosis of cleft lip and palate (1,981; 54.8%). Conclusion: Delayed primary labioplasty can affect daily functioning. Primary repair for patients with cleft lip and palate may be postponed due to limited awareness, socioeconomic factors, inadequate facilities, and varying adherence to treatment guidelines. Despite variations in the timing of primary cleft lip repair (not adhering to the recommended protocol), only 10% of these patients undergo reoperation. Healthcare providers should prioritize the importance of the ideal timing for primary repair in order to optimize physiological function without compromising the aesthetic results.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.29 no.5
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• pp.422-428
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• 2007

The columella, nasal tip, lip relationship in the secondary bilateral cleft deformity remains an enigma and a great challenge for the cleft surgeon. A subset of patients with bilateral cleft lip still require columellar lengthening and nasal correction, despite the advances in preoperative orthopedics and primary nasal corrections. An approach to correct this deformity is described. This consists of 1) lengthening the columella, 2) open rhinoplasty, allowing definitive repositioning of lower lateral cartilages, ear cartilage grafting to the tip and columella when necessary, 3) nasal mucosal advancement, 4) alar base narrowing and 5) reconstruction of the orbicularis oris as required. In surgical repair of the cleft lip nose, the timing of the operation(during lip closure, before or after the puberty growth sput), and the operative technique play a key role in the final result. In this study, 13 cleft lip patients who had undergone a secondary cheilorhinoplasty at the Department of Oral and Maxillofacial Surgery, Pusan National University Hospital were evaluated to check the proper time and method of the operation.

• Journal of Korea Multimedia Society
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• v.21 no.11
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• pp.1279-1287
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• 2018

In this paper, a new type of color coordinate conversion is proposed as modified CIEXYZ from RGB to compress the color gamut. The proposed segmentation includes principal component analysis for the optimal projection of a feature vector into a one-dimensional feature. The final step adopted for lip segmentation is Otsu's threshold for a two-class problem. The performance of the proposed method was better than that of conventional methods, especially for the chromatic feature.

• The Journal of Korean Academy of Prosthodontics
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• v.30 no.2
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• pp.259-271
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• 1992

This study was designed to investigate the criteria of the perfect smile that was necessary to improve the esthetic problem in oral and maxillo-facial region and treating the anterior tooth region. The author took the facial straight photograph of 240 university students(male : 129, female : 111) in a resting and a smiling position, measured and analized the lip pattern and the relation between the lip and the teeth when they were smiling. Besides, 10 members of committee for appraisal (dentist : 5 persons, professor of the college of fine arts : 5 persons) estimated the smiling pattern. After that the author have compared and analyzed the obtained results. The results obtained were as follows : 1. In the shape of the upper lip, when the upper lip curved downward, it was 42.92% , straight was 45.00% and curved upward was 12.08%. The group in which the upper lip curved upward was the most esthetic. 2. In the relation between the upper lip and the teeth, high smile was 29.17%, average smile was 55.83% and low smile was 15.00%. The group of average smile was the most esthetic. 3. In the parallel relation between the lower lip and maxillary anterior incisal curvature, the group of paralled was 60.42%, the group of straight was 34.17% and the group of reverse was 5.41%. The group of parallel was the most esthetic. 4. In the relationship between maxillary anterior incisor and lower lip, the group of the maxillary anterior incisor were slightly covered by the lower lip was 10.42%, the group of the maxillary anterior teeth touched to the lower lip was 35.83%, and the no-touching was 53.75%. The group of the maxillary anterior teeth touched to the lower lip was the most esthetic. 5. In the teeth displayed in a smile, displayed to the canine was 0.84%, displayed to the first premolar was 19.17%, displayed to the second premolar was 57.92%, displayed to the first molar was 20.00% and displayed to the second molar was 2.08%. The group of displayed to the first molar was the most esthetic. 6. At smiles, the width of the mouth corner was 0.46 times of the full face width, 0.95 times of the interpupillary distance, and 1.23 times of the resting position. 7. At smiles, the lengh of the upper lip was 0.71 times and lower lip was 0.93 times of the length in the resting position.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.36 no.5
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• pp.230-236
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• 2014

Esthetic reconstruction of cleft lip nose deformity is a challenging task in surgical management of patients with orofacial cleft. The author reconstructed cleft lip nose deformity effectively using autogenous auricular cartilage and a relatively new graft material of porcine dermal collagen, $Permacol^{TM}$. After correction of the deformed lower third of the nose with patient's auricular cartilage, we applied $Permacol^{TM}$ to augment the entire nasal dorsum. Three patients were treated and followed for up to five years. All patients improved in nose aesthetics without any inflammatory or immunogenic reaction. The author suggests that the use of $Permacol^{TM}$ for nasal profile augmentation in the treatment of cleft lip nose deformity is an alternative surgical strategy with minimal surgical invasiveness. The author report long-term experience with combined use of auricular cartilage and $Permacol^{TM}$ in nasal reconstruction for cleft lip nose deformity.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.41 no.3
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• pp.155-162
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• 2004

This paper concentrated on lip synchronization (lip sync) test for DTV with respect to audio and video signals using a finite digital bitstream In this paper, we propose a new lip sync test method which does not effect on the current program by use of the transient effect area test signals (TATS) and audio-video time index lip sync test signals (TILS).the experimental result shows that the time difference between audio and video signal can be easily measured by captured oscilloscope waveform at any time.

• Tribology and Lubricants
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• v.9 no.1
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• pp.32-37
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• 1993

The equations are derived for the evaluation of the axial contact forces. The contact forces of rubber seals are analyzed as a function of the ratio of real contact length, the thickness of seal lip, the inclined angle of seal lip, and the interference between the edge of seal lip and the rotating inner ring. The experimental apparatus is developed for the test of seal lip contact force. The data for designing rubber seals are presented in terms of the ratio of real contact length, initial inclined lip angle, lip thickness. and the interference. The results obtained from the derived equation for the contact force are in good agreement with the experimental results.

• KSTLE International Journal
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• v.1 no.1
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• pp.59-62
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• 2000

This paper deals with an experimental study on the dynamic response of an elastomeric oil seal when the interferences between shaft and lip as well as the dynamic eccentricities are present. The dynamic response of seal lip in oil seals was observed with the aid of an image processing apparatus. The temperature of the seal lip edge, friction torque and the dynamic sealing gap between shaft and lip are measured at different conditions of the initial interference and the shaft eccentricity, The data were simultaneously measured under dynamic conditions. Experimental results show that, as the shaft speed is increased, S/e$_{d}$ has nearly reached a constant asymptotic value fur a certain range of shaft speeds. The results indicate that the gap separation between shaft and lip is provided due to the shaft eccentricity because the seal lip cannot follow quickly the radial displacements with increasing shaft speed.d.

• The Journal of the Convergence on Culture Technology
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• v.3 no.3
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• pp.37-42
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• 2017

We are designed to control the lipoid variation of the structure system with the stratum corneum on the skin. The skin structure is consisted of a morphology how to use the lipoid component, and the given skin structure is consisted of the mechanical shapes of the intercellular route and transcellular route, and is confirmed to control the variation state of the structure capacity. The skin impedance is appeared to result the value of measurement such as shapes of ${\lambda}-Lip-RSC$, ${\lambda}-Lip-RSL$, ${\lambda}-Lip-CSG$, ${\lambda}-Lip-CSS$ and ${\lambda}-Lip-RSB$. The condition is showed to the alteration difference value of the intercellular route and transcellular route. And, composition condition is established to separate the division parts for conversion system that is constructed with the alteration modeling. We will be possible to progress the improvement effectiveness of the continuous skin control system on the skin.