• 한국환경보건학회:학술대회논문집
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• 한국환경보건학회 2005년도 국제학술대회
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• pp.311-314
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• 2005

To evaluate the acute effects of fine particles on pulmonary function, a longitudinal study was conducted. This study was carried out for the schoolchildren(3rd and 4th grades) living in Inner-Mongolia, China. 113 Chinese children were asked to record their daily levels of peak expiratory flow rate(PEPR) using portable peak flow meter(mini-Wright) for 40 days and 3 time everyday(12 April 2004 to 21 May 2004). The atmospheric concentration of fine particles in study area was also determined everyday during same period. The relationship between dailypeak expiratory flow rate(PEFR) and fine particle levels was analyzed using a mixed linear regression models including gender, age, height, the presence of respiratory symptoms, and daily average relative humidity as extraneous variables. The analysis showed that the increase of fine particle concentrations was negatively associated with the variability in PEPR. The IQR(inter-quartile range) increments of $PM_{10}$ or $PM_{2.5}(66.0{\mu}g/m^3$ and $118.9{\mu}g/m^3$, respectively) were also shown to be related with 1.422L/min(95% Confidence intervals: 0.270 ${\sim}$ 2.574) and 1.214L1min(95% Cl: 0.010 ${\sim}$ 2.418) decline in PEFR.

• Journal of the Korean Data and Information Science Society
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• 제27권4호
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• pp.935-946
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• 2016

본 연구에서는 한국고용정보원에서 실시한 "2013 고졸자 취업진로조사" 자료를 활용하여 특성화고 졸업자의 임금결정요인을 분석하였다. 그런데 임금은 개인수준의 인적특성 (1-수준)과 취업지역 수준의 산업특성 (2-수준)에 의해 영향을 받는 다층구조를 가지게 된다. 이와 같이 다층구조 자료특성을 가지는 복수의 분석단위 구조가 되면, 전통적인 회귀분석과 같이 개인수준의 임금이 독립이라는 가정을 할 수 없게 된다. 따라서 개인수준의 임금에 영향을 미치는 다층구조의 특성을 가진 변수들의 영향력을 분석하기 위한 타당한 방법으로 위계적 선형모형을 이용하였다. 그리고 전통적인 회귀분석과 위계적 선형모형의 비교를 통하여 다음과 같은 주요 결과를 얻었다. 첫째, 다층구조를 갖는 위계적 선형모형이 전통적인 회귀모형보다 통계적으로 유의함을 알 수 있었다. 둘째, 2-수준의 총근로시간과 상용직의 평균임금이 개인수준의 임금에 통계적으로 유의하게 영향을 미치는 것으로 나타났다. 셋째, 마이스터고 졸업생이 그렇지 않은 졸업생에 비해서, 부모의 소득이 높을수록 통계적으로 유의하게 개인수준의 임금이 높아짐을 알 수 있다. 넷째, 부모의 교육수준이 높을수록, 학점이 높을수록, 학교 만족도가 높고 자격증 수가 많을수록 임금이 높아짐을 알 수 있다. 마지막으로 2-수준의 산업특성을 고려한 랜덤효과가 통계적으로 유의하게 나타났다.

• Nuclear Engineering and Technology
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• 제54권9호
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• pp.3516-3525
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• 2022

The high capture cross-section (𝜎_c) of Gadolinium (Gd-155 and Gd-157) causes reactivity penalty and swing at the initial stage of fuel burnup in Pressurized Water Reactor (PWR). The present study is concerned with the feasibility of the combination of mixed burnable poison with both low and high 𝜎_c as an approach to minimize these effects. Two considered reference designs are fuel assemblies with 24 IBA rods of Gd₂O₃ and Er₂O₃ respectively. Models comprise nuclear fuel with a homogeneous mixture of Er₂O₃, AmO₂, SmO₂, and HfO₂ with Gd₂O₃ as well as the coating of PaO₂ and ZrB₂ on the Gd₂O₃ pellet's outer surface. The infinite multiplication factor was determined and reactivity was calculated considering 3% neutron leakage rate. All models except Er₂O₃ and SmO₂ showed expected results namely higher values of these parameters than the reference design of Gd₂O₃ at the early burnup period. The highest value was found for the model of PaO₂ and Gd₂O₃ followed by ZrB₂ and HfO₂. The cycle burnup, discharge burnup, and cycle length for three batch refueling were calculated using Linear Reactivity Model (LRM). The pin power distribution, energy-dependent neutron flux and Fuel Temperature Coefficient (FTC) were also studied. An optimization of model 1 was carried out to investigate effects of different isotopic compositions of Gd₂O₃ and absorber coating thickness.

• 말소리와 음성과학
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• 제15권4호
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• pp.1-10
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• 2023

본 연구에서는 AI Hub에 구축된 '교육용 한국인의 영어 음성 데이터'에 있는 발음 평가 데이터를 활용하여 철자 기반 발화 속도 및 조음 속도와 음절 기반 발화 속도 및 조음 속도 중 발음 정확성 및 운율 유창성, 합산 점수를 예측하는 모델에 어떤 요소가 더 유의미한 영향을 미치는지 분석하였다. 이를 위해 13세, 19세, 26세 연령별, 성별, 수준별로 이 코퍼스의 훈련 데이터에서 총 900개 발화를 추출하여 데이터에 포함된 다양한 요소를 활용해 평가 점수를 예측하는 선형효과분석을 실행하였다. 선형효과분석에서 최적의 세 개 모델을 통해 예측된 평가 점수를 검증 데이터에서 추출한 총 180개 발화의 평가 점수와 얼마나 상관관계가 있는지도 분석하였다. 분석 결과 발음의 정확성과 운율의 유창성, 합산 점수 예측 모델 모두 철자 기반 발화 속도와 조음 속도보다 음절 기반 발화 속도와 조음 속도가 평가 점수를 예측하는데 더 큰 영향을 주는 것으로 밝혀졌다. 모델에서 예측한 점수와 검정 데이터의 실제 점수와의 상관계수는 .65에서 .68 사이로 각 모델의 평가 점수 예측력이 나쁘지 않았다. 발화 속도와 조음 속도 간에 어떤 요소가 더 큰 영향을 미치는지는 본 연구를 통해 밝혀내지 못하였다.

• Journal of Preventive Medicine and Public Health
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• 제48권3호
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• pp.151-169
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• 2015

Objectives: The deleterious effects of air pollution on various health outcomes have been demonstrated. However, few studies have examined the effects of air pollution on liver enzyme levels. Methods: Blood samples were drawn up to three times between 2008 and 2010 from 545 elderly individuals who regularly visited a community welfare center in Seoul, Korea. Data regarding ambient air pollutants (particulate matter ${\leq}2.5{\mu}m$ [$PM_{2.5}$], nitrogen dioxide [$NO_2$], ozone [$O_3$], carbon monoxide, and sulfur dioxide) from monitoring stations were used to estimate air pollution exposure. The effects of the air pollutants on the concentrations of three liver enzymes (aspartate aminotransferase [AST], alanine aminotransferase [ALT], and ${\gamma}$-glutamyltranspeptidase [${\gamma}$-GTP)]) were evaluated using generalized additive and linear mixed models. Results: Interquartile range increases in the concentrations of the pollutants showed significant associations of $PM_{2.5}$ with AST (3.0% increase, p=0.0052), ALT (3.2% increase, p=0.0313), and ${\gamma}$-GTP (5.0% increase, p=0.0051) levels; $NO_2$ with AST (3.5% increase, p=0.0060) and ALT (3.8% increase, p=0.0179) levels; and $O_3$ with ${\gamma}$-GTP (5.3% increase, p=0.0324) levels. Significant modification of these effects by exercise and alcohol consumption was found (p for interaction <0.05). The effects of air pollutants were greater in non-exercisers and heavy drinkers. Conclusions: Short-term exposure to air pollutants such as $PM_{2.5}$, $NO_2$, and $O_3$ is associated with increased liver enzyme levels in the elderly. These adverse effects can be reduced by exercising regularly and abstinence from alcohol.

• Asian-Australasian Journal of Animal Sciences
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• 제33권8호
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• pp.1360-1368
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• 2020

Objective: The aim of our study was to determine the associations of heifer reproductive performance with survival up to the first calving, first-lactation milk yield, and the probability of being culled within 50 days after first calving. Methods: Data from 33 large Holstein-Friesian commercial dairy herds were gathered from the official milk recording database in Hungary. The data of heifers first inseminated between January 1, 2011 and December 31, 2014 were analyzed retrospectively, using Cox proportional hazards models, competing risks models, multivariate linear and logistic mixed-effects models. Results: Heifers (n = 35,128) with younger age at conception were more likely to remain in the herd until calving, and each additional month in age at conception increased culling risk by 5.1%. Season of birth was related to first-lactation milk yield (MY1; n = 19,931), with cows born in autumn having the highest milk production (p<0.001). The highest MY1 was achieved by heifers that first calved between 22.00 and 25.99 months of age. Heifers that calved in autumn had the highest MY1, whereas calving in summer was related to the lowest milk production (p<0.001). The risk of culling within 50 days in milk in first lactation (n = 21,225) increased along with first calving age, e.g. heifers that first calved after 30 months of age were 5.52-times more likely to be culled compared to heifers that calved before 22 months of age (p<0.001). Calving difficulty was related to higher culling risk in early lactation (p<0.001). Heifers that required caesarean section were 24.01-times more likely to leave the herd within 50 days after first calving compared to heifers that needed no assistance (p<0.001). Conclusion: Reproductive performance of replacement heifers is closely linked to longevity and milk production in dairy herds.

• 한국수산과학회지
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• 제56권4호
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• pp.411-418
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• 2023

Genome wide association studies (GWAS) identify genetic loci associated with quantitative traits in genomic selection. Although several studies have compared performance of various algorithms, no study compares them in olive flounder Paralichthys olivaceus. This study compared the GWAS results of four mixed linear model (MLM) algorithms and one Fixed and random model Circulating Probability Unification (FarmCPU) algorithm in olive flounder. Considering gender and genetic association matrices as fixed and random effects, the MLM had stable performance without inflation for λ_GC (genomic inflation factor) of -log₁₀P. The FarmCPU algorithm had some appropriate λ_GC of -log₁₀P, and an upward tail was identified in quantile-quantile plots. Therefore, the models were suitable for detecting genetic variants associated with olive flounder growth traits. Moreover, significant genotypes appeared several times at chromosome 22, around which quantitative trait loci are expected to exist. Finally, in both models, some of the most genetic variants were found in genes related to growth traits, confirming their reliability. These results will be helpful when applied to the genomic selection of olive flounder growth traits in the future.

• Earthquakes and Structures
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• 제3권1호
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• pp.1-15
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• 2012

An empirical predictive relationship correlating bracketed duration to earthquake magnitude, site-to-source distance, and local site conditions (i.e. rock vs. stiff soil) for stable continental regions of North America is presented herein. The correlation was developed from data from 620 horizontal motions for central and eastern North America (CENA), consisting of 28 recorded motions and 592 scaled motions. The bracketed duration data was comprised of nonzero and zero durations. The non-linear mixed-effects regression technique was used to fit a predictive model to the nonzero duration data. To account for the zero duration data, logistic regression was conducted to model the probability of zero duration occurrences. Then, the probability models were applied as weighting functions to the NLME regression results. Comparing the bracketed durations for CENA motions with those from active shallow crustal regions (e.g. western North America: WNA), the motions in CENA have longer bracketed durations than those in the WNA. Especially for larger magnitudes at far distances, the bracketed durations in CENA tend to be significantly longer than those in WNA.

• Asian-Australasian Journal of Animal Sciences
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• 제30권4호
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• pp.455-461
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• 2017

Objective: Polymorphisms occurring in the precursor region of microRNAs (miRNAs) affect the target gene and alter the biogenesis of miRNAs, resulting in phenotypic variation. The purpose of the study was to investigate the genetic effects of rs16681031 (C>G) mutation in the precursor region of gga-miR-1658 on the economic traits of the Gushi-Anka chicken F2 resource population. Methods: To explore the effect of miR-1658 polymorphisms on chicken economic traits, the SNP was genotyped by MassArray matrix-assisted laser desorption/ionization-time of flight mass spectrometry. The association between the SNP and chicken body size, growth and carcass traits was determined by linear mixed models. Results: The SNP was not only significantly associated with body weight at the age of 6, 8, 10, 12 weeks, respectively, but also with the breadth of the chicken chest, body slanting length and pelvic breadth at 4 weeks, chest depth at 8 weeks of age, and body slanting length at 12 weeks (p<0.05), respectively. Conclusion: Our data serve as a useful resource for further analysis of miRNA function, and represent a molecular genetic basis for poultry breeding.

• 대한간호학회지
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• 제49권2호
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• pp.126-136
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• 2019

Purpose: This study was conducted to evaluate the effect of breast milk olfactory stimulation on physiological responses, oral feeding progression, and body weight in preterm infants. Methods: A repeated measures design with nonequivalent control group was used. The participants were healthy, preterm infants born at a gestational age of 28~32 weeks; 12 in the experimental group and 16 in the control group. Data were collected prospectively in the experimental group, and retrospectively in the control group, by the same methods. Breast milk olfactory stimulation was provided 12 times over 15 days. The data were analyzed using the chi-square test, Mann-Whitney U test, Wilcoxon signed rank test and linear mixed models using SPSS 19. Results: The gastric residual volume (GRV) of the experimental group was significantly less than that of the control group. The heart rate, oxygen saturation, respiration rate, transition time to oral feeding, and body weight were not significantly different between the two groups. Conclusion: These findings indicate that breast milk olfactory stimulation reduces GRV and improves digestive function in preterm infants without inducing distress.