• Title/Summary/Keyword: Linear Array

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Simultaneous Determination of Berberine, Cinnamic Acid and Glycyrrhizin in Pharmaceutical Formulations by Capillary Electrophoresis with Diode-Array Detection (모세관 전기이동법에 의한 생약제제중 베르베린, 계피산 및 글리시리진의 동시 정량)

  • Kang, Seong Ho;Chung, Wha Jin;Yoon, Hyung Jung;Chung, Doo Soo
    • Journal of the Korean Chemical Society
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    • v.41 no.2
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    • pp.98-104
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    • 1997
  • A simple, accurate and reproducible capillary electrophoresis(CE) assay has been developed for the determination of berberine, cinnamic acid, and glycyrrhizin which are used in traditional Korean medicinal preparations. Separation of these compounds was performed in 20 mM phosphate buffer(pH 7.5) and acetonitrile(75:25, v/v) using a bare fused silica capillary($57 cm{\times}75 {\mu}m$ i.d.) at 25$^{\circ}C$. With the electric field of 350 V/cm, the time needed for the separation of berberine, cinnamic acid and glycyrrhizin was within 13 min. Calibration curves were linear for 1∼100 ${\mu}g/mL$ berberine, 0.3∼100 ${\mu}g/mL$ cinnamic acid and 2.5∼100 ${\mu}g/mL$ glycyrrhizin. The ranges of relative standard deviations(n=5) for those samples were between 0.96∼2.35%. The limits of detection(S/N=3) for berberine, cinnamic acid and glycyrrhizin were 0.5, 0.1 and 2.0 ${\mu}g/mL$, respectively. The numbers of theoretical plates were 181,000(berberine), 88,000(cinnamic acid) and 169,000(glycyrrhizin), while they were 3,100∼4,800 in HPLC.

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Microcrack Orientations in Bulgugsa Granites from Southwestern Gyeongsang Basin (경상분지 남서부 일대의 불국사 화강암류에서 발달하는 미세균열의 방향성)

  • Park, Deok-Won
    • The Journal of the Petrological Society of Korea
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    • v.17 no.4
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    • pp.206-221
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    • 2008
  • We have studied general orientational characteristics of microcracks distributed in Bulgugsa Granites of southwestern Gyeongsang Basin. Microcracks of 131 sets, which were developed on horizontal surfaces of II rock samples collected from Sacheon-Gosung, Geoje-si and Namhae-gun areas, were distinguished by image processing. Then, 45 sets with a distinct linear array on image were sorted out. These microcracks can be comparable with vertical grain planes. Orientations of these microcracks were compared with those of vertical rift and grain planes developed in Cretaceous and Jurassic granites of Korea. In the distribution chart, the agreement of the distribution pattern between microcracks of 45 sets and above vertical planes suggests that microcrack systems developed all over the study area also occur regionally in Cretaceous and Jurassic granites of Korea. Whole domain of the directional angle-frequency chart can be divided into 20 domains in terms of the phases of the distribution of microcracks. Meanwhile, 18 domains from 45 sets of microcracks were compared with the maximum principal stress orientations suggested from previous studies. The majority of maximum principal stress orientations pertain to domain $1{\sim}2$, $5{\sim}6$, $11{\sim}15$, $17{\sim}18$ and $19{\sim}20$, and these domains are coincident with the orientation of the 1st and 2nd-frequency orders represented in a rose diagram for 45 sets of microcracks. Representative orientations of open microcrack reflect the maximum principal stress orientations suggested in previous studies.

Oribicularis Oris Muscle Defects in Philtral Deformities in the Repaired Cleft Lip (구순열 수술 후 인중의 변형과 구륜근 결손)

  • Kim, Suk-Wha;Jeong, Yeon-Woo;Cheon, Jung-Eun;Park, Chan-Young;Oh, Myung-June;Kim, Jung-Hong;Choi, Tae-Hyun
    • Archives of Plastic Surgery
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    • v.37 no.4
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    • pp.427-432
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    • 2010
  • Purpose: The purpose of this study is to estimate muscle defect by ultrasonography in the patients with secondary deformities of the lip. We investigated the association between the muscle defect in the repaired cleft lip and the philtral appearance not only at resting state but also maximal puckering. Methods: From December 2006 to November 2007, 52 children were evaluated after primary or secondary cheiloplasty. Digital photographs were taken both from the front and both three quarter views in repose and at maximal pucker. Video clips were also taken in repose and at maximal pucker. A panel of four, scored the philtral ridge and dimple seen on these photographs and videos by using two visual analog scales. Eminence of the philtral ridge was scored by a 5 point grading scale, from "conspicuous groove" to "normal philtral ridge" and the philtral dimple was scored by 3 point grading scale, from "no dimple" to "prominent dimple". Ultrasound images of the upper lip were made using a linear array transducer at the resting position of the lip and evaluated by a single radiologist. Results: The philtral ridge eminence scored $2.79{\pm}0.54$ and $1.40{\pm}0.53$ at resting and maximal pucker, correlating with "flat" and "conspicous groove". The philtral dimpling scored $1.44{\pm}0.53$ and $2.27{\pm}0.66$ at resting and maximal pucker, correlating with "no dimple" and "slight dimple". Ultrasound imaging showed the average muscle dehiscence to be $3.78{\pm}2.14$ mm at resting position. Correlation between the muscle defect in ultrasound imaging and philtral ridge eminence at rest was statistically significant (p<0.050), but was not significant (p=0.756) at maximal pucker using Spearman's rank correlation. Correlation between the muscle defect in ultrasound imaging and philtral dimpling was not statistically significant both at rest (p=0.920) and at maximal pucker (p=0.815) using Spearman's rank correlation. Conclusion: Quantitative assessment of the muscle defect using ultrasonography correlates with the static philtral appearance, but does not correlate with the dynamic appearance. Also, the size of the muscle defect does not show any correlation with the philtral dimpling. Our findings reveal that ultrasound imaging partially reflect static appearance of philtrum but cannot reflect dynamic appearance and suggest the need for further research to evaluate dynamic appearance.

Effectiveness of multi-mode surface wave inversion in shallow engineering site investigations (토목관련 천부층 조사에서 다중 모드 표면파 역산의 효과)

  • Feng Shaokong;Sugiyama Takeshi;Yamanaka Hiroaki
    • Geophysics and Geophysical Exploration
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    • v.8 no.1
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    • pp.26-33
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    • 2005
  • Inversion of multi-mode surface-wave phase velocity for shallow engineering site investigation has received much attention in recent years. A sensitivity analysis and inversion of both synthetic and field data demonstrates the greater effectiveness of this method over employing the fundamental mode alone. Perturbation of thickness and shear-wave velocity parameters in multi-modal Rayleigh wave phase velocities revealed that the sensitivities of higher modes: (a) concentrate in different frequency bands, and (b) are greater than the fundamental mode for deeper parameters. These observations suggest that multi-mode phase velocity inversion can provide better parameter discrimination and imaging of deep structure, especially with a velocity reversal, than can inversion of fundamental mode data alone. An inversion of the theoretical phase velocities in a model with a low velocity layer at 20 m depth can only image the soft layer when the first higher mode is incorporated. This is especially important when the lowest measurable frequency is only 6 Hz. Field tests were conducted at sites surveyed by borehole and PS logging. At the first site, an array microtremor survey, often used for deep geological surveying in Japan, was used to survey the soil down to 35 m depth. At the second site, linear multichannel spreads with a sledgehammer source were recorded, for an investigation down to 12 m depth. The f-k power spectrum method was applied for dispersion analysis, and velocities up to the second higher mode were observed in each test. The multi-mode inversion results agree well with PS logs, but models estimated from the fundamental mode alone show f large underestimation of the depth to shallow soft layers below artificial fill.

Implementation of RSA modular exponentiator using Division Chain (나눗셈 체인을 이용한 RSA 모듈로 멱승기의 구현)

  • 김성두;정용진
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.12 no.2
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    • pp.21-34
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    • 2002
  • In this paper we propos a new hardware architecture of modular exponentiation using a division chain method which has been proposed in (2). Modular exponentiation using the division chain is performed by receding an exponent E as a mixed form of multiplication and addition with divisors d=2 or $d=2^I +1$ and respective remainders r. This calculates the modular exponentiation in about $1.4log_2$E multiplications on average which is much less iterations than $2log_2$E of conventional Binary Method. We designed a linear systolic array multiplier with pipelining and used a horizontal projection on its data dependence graph. So, for k-bit key, two k-bit data frames can be inputted simultaneously and two modular multipliers, each consisting of k/2+3 PE(Processing Element)s, can operate in parallel to accomplish 100% throughput. We propose a new encoding scheme to represent divisors and remainders of the division chain to keep regularity of the data path. When it is synthesized to ASIC using Samsung 0.5 um CMOS standard cell library, the critical path delay is 4.24ns, and resulting performance is estimated to be abort 140 Kbps for a 1024-bit data frame at 200Mhz clock In decryption process, the speed can be enhanced to 560kbps by using CRT(Chinese Remainder Theorem). Futhermore, to satisfy real time requirements we can choose small public exponent E, such as 3,17 or $2^{16} +1$, in encryption and verification process. in which case the performance can reach 7.3Mbps.

Analysis of statistical characteristics of bistatic reverberation in the east sea (동해 해역에서 양상태 잔향음 통계적 특징 분석)

  • Yeom, Su-Hyeon;Yoon, Seunghyun;Yang, Haesang;Seong, Woojae
    • The Journal of the Acoustical Society of Korea
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    • v.41 no.4
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    • pp.435-445
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    • 2022
  • In this study, the reverberation of a bistatic sonar operated in southeastern coast in the East Sea in July 2020 was analyzed. The reverberation sensor data were collected through an LFM sound source towed by a research vessel and a horizontal line array receiver 1 km to 5 km away from it. The reverberation sensor data was analyzed by various methods including geo-plot after signal processing. Through this, it was confirmed that the angle reflected from the sound source through the scatterer to the receiver has a dominant influence on the distribution of the reverberation sound, and the probability distribution characteristics of bistatic sonar reverberation varies for each beam. In addition, parametric factors of K distribution and Rayleigh distribution were estimated from the sample through moment method estimation. Using the Kolmogorov-Smirnov test at the confidence level of 0.05, the distribution probability of the data was analyzed. As a result, it could be observed that the reverberation follows a Rayleigh probability distribution, and it could be estimated that this was the effect of a low reverberation to noise ratio.

Transferring Calibrations Between on Farm Whole Grain NIR Analysers

  • Clancy, Phillip J.
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1210-1210
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    • 2001
  • On farm analysis of protein, moisture and oil in cereals and oil seeds is quickly being adopted by Australian farmers. The benefits of being able to measure protein and oil in grains and oil seeds are several : $\square$ Optimize crop payments $\square$ Monitor effects of fertilization $\square$ Blend on farm to meet market requirements $\square$ Off farm marketing - sell crop with load by load analysis However farmers are not NIR spectroscopists and the process of calibrating instruments has to the duty of the supplier. With the potential number of On Farm analyser being in the thousands, then the task of calibrating each instrument would be impossible, let alone the problems encountered with updating calibrations from season to season. As such, NIR technology Australia has developed a mechanism for \ulcorner\ulcorner\ulcorner their range of Cropscan 2000G NIR analysers so that a single calibration can be transferred from the master instrument to every slave instrument. Whole grain analysis has been developed over the last 10 years using Near Infrared Transmission through a sample of grain with a pathlength varying from 5-30mm. A continuous spectrum from 800-1100nm is the optimal wavelength coverage fro these applications and a grating based spectrophotometer has proven to provide the best means of producing this spectrum. The most important aspect of standardizing NIB instruments is to duplicate the spectral information. The task is to align spectrum from the slave instruments to the master instrument in terms of wavelength positioning and then to adjust the spectral response at each wavelength in order that the slave instruments mimic the master instrument. The Cropscan 2000G and 2000B Whole Grain Analyser use flat field spectrographs to produce a spectrum from 720-1100nm and a silicon photodiode array detector to collect the spectrum at approximately 10nm intervals. The concave holographic gratings used in the flat field spectrographs are produced by a process of photo lithography. As such each grating is an exact replica of the original. To align wavelengths in these instruments, NIR wheat sample scanned on the master and the slave instruments provides three check points in the spectrum to make a more exact alignment. Once the wavelengths are matched then many samples of wheat, approximately 10, exhibiting absorbances from 2 to 4.5 Abu, are scanned on the master and then on each slave. Using a simple linear regression technique, a slope and bias adjustment is made for each pixel of the detector. This process corrects the spectral response at each wavelength so that the slave instruments produce the same spectra as the master instrument. It is important to use as broad a range of absorbances in the samples so that a good slope and bias estimate can be calculated. These Slope and Bias (S'||'&'||'B) factors are then downloaded into the slave instruments. Calibrations developed on the master instrument can then be downloaded onto the slave instruments and perform similarly to the master instrument. The data shown in this paper illustrates the process of calculating these S'||'&'||'B factors and the transfer of calibrations for wheat, barley and sorghum between several instruments.

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L-band SAR-derived Sea Surface Wind Retrieval off the East Coast of Korea and Error Characteristics (L밴드 인공위성 SAR를 이용한 동해 연안 해상풍 산출 및 오차 특성)

  • Kim, Tae-Sung;Park, Kyung-Ae;Choi, Won-Moon;Hong, Sungwook;Choi, Byoung-Cheol;Shin, Inchul;Kim, Kyung-Ryul
    • Korean Journal of Remote Sensing
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    • v.28 no.5
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    • pp.477-487
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    • 2012
  • Sea surface winds in the sea off the east coast of Korea were derived from L-band ALOS (Advanced Land Observing Satellite) PALSAR (Phased Array type L-band Synthetic Aperture Radar) data and their characteristics of errors were analyzed. We could retrieve high-resolution wind vectors off the east coast of Korea including the coastal region, which has been substantially unavailable from satellite scatterometers. Retrieved SAR-wind speeds showed a good agreement with in-situ buoy measurement by showing relatively small an root-mean-square (RMS) error of 0.67 m/s. Comparisons of the wind vectors from SAR and scatterometer presented RMS errors of 2.16 m/s and $19.24^{\circ}$, 3.62 m/s and $28.02^{\circ}$ for L-band GMF (Geophysical Model Function) algorithm 2009 and 2007, respectively, which tended to be somewhat higher than the expected limit of satellite scatterometer winds errors. L-band SAR-derived wind field exhibited the characteristic dependence on wind direction and incidence angle. The previous version (L-band GMF 2007) revealed large errors at small incidence angles of less than $21^{\circ}$. By contrast, the L-band GMF 2009, which improved the effect of incidence angle on the model function by considering a quadratic function instead of a linear relationship, greatly enhanced the quality of wind speed from 6.80 m/s to 1.14 m/s at small incident angles. This study addressed that the causes of wind retrieval errors should be intensively studied for diverse applications of L-band SAR-derived winds, especially in terms of the effects of wind direction and incidence angle, and other potential error sources.

Four-Channel Differential CMOS Optical Transimpedance Amplifier Arrays for Panoramic Scan LADAR Systems (파노라믹 스캔 라이다 시스템용 4-채널 차동 CMOS 광트랜스 임피던스 증폭기 어레이)

  • Kim, Sang Gyun;Jung, Seung Hwan;Kim, Seung Hoon;Ying, Xiao;Choi, Hanbyul;Hong, Chaerin;Lee, Kyungmin;Eo, Yun Seong;Park, Sung Min
    • Journal of the Institute of Electronics and Information Engineers
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    • v.51 no.9
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    • pp.82-90
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    • 2014
  • In this paper, a couple of 4-channel differential transimpedance amplifier arrays are realized in a standard 0.18um CMOS technology for the applications of linear LADAR(laser detection and ranging) systems. Each array targets 1.25-Gb/s operations, where the current-mode chip consists of current-mirror input stage, a single-to-differential amplifier, and an output buffer. The input stage exploits the local feedback current-mirror configuration for low input resistance and low noise characteristics. Measurements demonstrate that each channel achieves $69-dB{\Omega}$ transimpedance gain, 2.2-GHz bandwidth, 21.5-pA/sqrt(Hz) average noise current spectral density (corresponding to the optical sensitivity of -20.5-dBm), and the 4-channel total power dissipation of 147.6-mW from a single 1.8-V supply. The measured eye-diagrams confirms wide and clear eye-openings for 1.25-Gb/s operations. Meanwhile, the voltage-mode chip consists of inverter input stage for low noise characteristics, a single-to-differential amplifier, and an output buffer. Test chips reveal that each channel achieves $73-dB{\Omega}$ transimpedance gain, 1.1-GHz bandwidth, 13.2-pA/sqrt(Hz) average noise current spectral density (corresponding to the optical sensitivity of -22.8-dBm), and the 4-channel total power dissipation of 138.4-mW from a single 1.8-V supply. The measured eye-diagrams confirms wide and clear eye-openings for 1.25-Gb/s operations.

Characteristics of Sea Water Intrusion Using Geostatistical Analysis of Geophysical Surveys at the Southeastern Coastal Area of Busan, Korea (지구물리 탐사자료의 지구통계학적 분석에 의한 부산 동남해안 지역의 해수침투 특성)

  • 심병완;정상용;김희준;성익환;김병우
    • Journal of Soil and Groundwater Environment
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    • v.7 no.3
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    • pp.3-17
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    • 2002
  • Data analysis of groundwater monitoring wells and geostatistical methods are used to identify the local characteristics of sea water intrusion and the range of sea water intrusion at the southeastern coastal area of Busan, Korea. Rainfall and groundwater level of two monitoring wells show a linear correlation because of the direct groundwater recharge by the precipitation. However, rainfall and electric conductivity have the inverse relationship because of the increase of groundwater. Electric conductivity rapidly increased at 24m depth and exceeded 20,000$\mu\textrm{s}$/cm near 26m depth in the monitoring wells. The variations of groundwater level and electric conductivity show that the interface between sea water and fresh water tends to move upward when groundwater level goes down. In the cross correlation analysis, groundwater level versus rainfall represents the largest cross correlation coefficient in 0 time lag but the cross correlation coefficient of electric conductivity versus rainfall is the largest when the time lag is 9 days. This suggests that the fluctuations of groundwater level respond to rainfall in a short time, but the interface between sea water and fresh water respond very slow to rainfall. Horizontal extents of sea water intrusion are estimated to 14 m from the east of Line 1, and 25 m from the southeast end of Line 2 in the inversion of dipole-dipole profiling data of two survey lines. The data of VES by the Schulumberger array in May and July show lognormal distributions. In the kriged apparent resistivity and earth resistivity distributions, the resistivities of July are increased comparing to those of May. This reflects that the concentration of sea water in aquifer is reduced due to the increased groundwater recharge from the rainfall in June and July. In analyzing the vertical and horizontal apparent resistivities and earth resistivity distributions, the geostatistical methods are very useful to identify the variations of earth resistivity distributions at the coastal area.