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Simultaneous determination of 30 ginsenosides in Panax ginseng preparations using ultra performance liquid chromatography

  • Park, Hee-Won;In, Gyo;Han, Sung-Tai;Lee, Myoung-Woo;Kim, So-Young;Kim, Kyung-Tack;Cho, Byung-Goo;Han, Gyeong-Ho;Chang, Il-Moo
    • Journal of Ginseng Research
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    • v.37 no.4
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    • pp.457-467
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    • 2013
  • A quick and simple method for simultaneous determination of the 30 ginsenosides (ginsenoside Ro, Rb1, Rb2, Rc, Rd, Re, Rf, Rg1, 20(S)-Rg2, 20(R)-Rg2, 20(S)-Rg3, 20(R)-Rg3, 20(S)-Rh1, 20(S)-Rh2, 20(R)-Rh2, F1, F2, F4, Ra1, Rg6, Rh4, Rk3, Rg5, Rk1, Rb3, Rk2, Rh3, compound Y, compound K, and notoginsenoside R1) in Panax ginseng preparations was developed and validated by an ultra performance liquid chromatography photo diode array detector. The separation of the 30 ginsenosides was efficiently undertaken on the Acquity BEH C-18 column with gradient elution with phosphoric acids. Especially the chromatogram of the ginsenoside Ro was dramatically enhanced by adding phosphoric acid. Under optimized conditions, the detection limits were 0.4 to 1.7 mg/L and the calibration curves of the peak areas for the 30 ginsenosides were linear over three orders of magnitude with a correlation coefficients greater than 0.999. The accuracy of the method was tested by a recovery measurement of the spiked samples which yielded good results of 89% to 118%. From these overall results, the proposed method may be helpful in the development and quality of P. ginseng preparations because of its wide range of applications due to the simultaneous analysis of many kinds of ginsenosides.

Investigation of axial-injection end-burning hybrid rocket motor regression

  • Saito, Yuji;Yokoi, Toshiki;Neumann, Lukas;Yasukochi, Hiroyuki;Soeda, Kentaro;Totani, Tsuyoshi;Wakita, Masashi;Nagata, Harunori
    • Advances in aircraft and spacecraft science
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    • v.4 no.3
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    • pp.281-296
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    • 2017
  • The axial-injection end-burning hybrid rocket proposed twenty years ago by the authors recently recaptured the attention of researchers for its virtues such as no ${\zeta}$ (oxidizer to fuel mass ratio) shift during firing and good throttling characteristics. This paper is the first report verifying these virtues using a laboratory scale motor. There are several requirements for realizing this type of hybrid rocket: 1) high fuel filling rate for obtaining an optimal ${\zeta}$; 2) small port intervals for increasing port merging rate; 3) ports arrayed across the entire fuel section. Because these requirements could not be satisfied by common manufacturing methods, no previous researchers have conducted experiments with this kind of hybrid rocket. Recent advances in high accuracy 3D printing now allow for fuel to be produced that meets these three requirements. The fuel grains used in this study were produced by a high precision light polymerized 3D printer. Each grain consisted of an array of 0.3 mm diameter ports for a fuel filling rate of 98% .The authors conducted several firing tests with various oxidizer mass flow rates and chamber pressures, and analysed the results, including ${\zeta}$ history, using a new reconstruction technique. The results show that ${\zeta}$ remains almost constant throughout tests of varying oxidizer mass flow rates, and that regression rate in the axial direction is a nearly linear function of chamber pressure with a pressure exponent of 0.996.

Estimation and Classification of Flow Regimes for South Korean Streams and River

  • Park, Kyug Seo;Choi, Ji-Woong;Park, Chan-Seo;An, Kwang-Guk;Wiley, Michael J.
    • Proceedings of the Korea Water Resources Association Conference
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    • 2015.05a
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    • pp.106-106
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    • 2015
  • The information of flow regimes continues to be norm in water resource and watershed management, in that stream flow regime is a crucial factor influencing water quality, geomorphology, and the community structure of stream biota. The objectives of this study were to estimate Korean stream flows from landscape variables, classify stream flow gages using hydraulic characteristics, and then apply these methods to ungaged biological monitoring sites for effective ecological assessment. Here I used a linear modeling approach (MLR, PCA, and PCR) to describe and predict seasonal flow statistics from landscape variables. MLR models were successfully built for a range of exceedance discharges and time frames (annual, January, May, July, and October), and these models explained a high degree of the observed variation with r squares ranging from 0.555 (Q95 in January) to 0.899 (Q05 in July). In validation testing, predicted and observed exceedance discharges were all significantly correlated (p<0.01) and for most models no significant difference was found between predicted and observed values (Paired samples T-test; p>0.05). I classified Korean stream flow regimes with respect to hydraulic and hydrologic regime into four categories: flashier and higher-powered (F-HP), flashier and lower-powered (F-LP), more stable and higher-powered (S-HP), and more stable and lower-powered (S-LP). These four categories of Korean streams were related to with the characteristics of environmental variables, such as catchment size, site slope, stream order, and land use patterns. I then applied the models at 684 ungaged biological sampling sites used in the National Aquatic Ecological Monitoring Program in order to classify them with respect to basic hydrologic characteristics and similarity to the government's array of hydrologic gauging stations. Flashier-lower powered sites appeared to be relatively over-represented and more stable-higher powered sites under-represented in the bioassessment data sets.

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Suppression of side lobe and grating lobe in ultrasound medical imaging system (의료용 초음파 영상 시스템에서 부엽과 격자엽의 억제)

  • Jeong, Mok Kun
    • The Journal of the Acoustical Society of Korea
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    • v.41 no.5
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    • pp.525-533
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    • 2022
  • We propose an effective method for suppressing both side and grating lobes by applying 2-dimensional Fourier Transform to the received channel data during the receive focusing process of an ultrasound imaging system. When the signal from the image point is focused, the channel signals have the same DC value across the channels. However, even after echoes from outside an imaging point are focused, they are manifested as having different spatial frequencies depending on their incident angles. Therefore, after the receive focusing delay time is applied, 2-D Fourier Transform is performed on the time-channel data to separate the DC component and other frequency components in the spectral domain, and the weighting value is defined using the ratio of the two values. The side lobe and grating lobe were suppressed by multiplying the ultrasound image by a weighting value. Ultrasound images with a frequency of 5 MHz were simulated in a 64-channel linear array. The grating lobe appearing in the ultrasound image was completely removed by applying the proposed method. In addition, the side lobe was reduced and the lateral resolution was greatly increased. Results of computer simulation on a human organ mimicking image show that the proposed method can aid in better lesion diagnosis by increasing the image contrast.

Correlation Matrix Generation Technique with High Robustness for Subspace-based DoA Estimation (부공간 기반 도래각 추정을 위한 높은 강건성을 지닌 상관행렬 생성 기법)

  • Byeon, BuKeun
    • Journal of Advanced Navigation Technology
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    • v.26 no.3
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    • pp.166-171
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    • 2022
  • In this paper, we propose an algorithm to improve DoA(direction of arrival) estimation performance of the subspace-based method by generating high robustness correlation matrix of the signals incident on the uniformly linear array antenna. The existing subspace-based DoA estimation method estimates the DoA by obtaining a correlation matrix and dividing it into a signal subspace and a noise subspace. However, the component of the correlation matrix obtained from the low SNR and small number of snapshots inaccurately estimates the signal subspace due to the noise component of the antenna, thereby degrading the DoA estimation performance. Therefore a robust correlation matrix is generated by arranging virtual signal vectors obtained from the existing correlation matrix in a sliding manner. As a result of simulation using MUSIC and ESPRIT, which are representative subspace-based methods,, the computational complexity increased by less than 2.5% compared to the existing correlation matrix, but both MUSIC and ESPRIT based on RMSE 1° showed superior DoA estimation performance with an SNR of 3dB or more.

Development of Automatic Peach Grading System using NIR Spectroscopy

  • Lee, Kang-J.;Choi, Kyu H.;Choi, Dong S.
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1267-1267
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    • 2001
  • The existing fruit sorter has the method of tilting tray and extracting fruits by the action of solenoid or springs. In peaches, the most sort processing is supported by man because the sorter make fatal damage to peaches. In order to sustain commodity and quality of peach non-destructive, non-contact and real time based sorter was needed. This study was performed to develop peach sorter using near-infrared spectroscopy in real time and nondestructively. The prototype was developed to decrease internal and external damage of peach caused by the sorter, which had a way of extracting tray with it. To decrease positioning error of measuring sugar contents in peaches, fiber optic with two direction diverged was developed and attached to the prototype. The program for sorting and operating the prototype was developed using visual basic 6.0 language to measure several quality index such as chlorophyll, some defect, sugar contents. The all sorting result was saved to return farmers for being index of good quality production. Using the prototype, program and MLR(multiple linear regression) model, it was possible to estimate sugar content of peaches with the determination coefficient of 0.71 and SEC of 0.42bx using 16 wavelengths. The developed MLR model had determination coefficient of 0.69, and SEP of 0.49bx, it was better result than single point measurement of 1999's. The peach sweetness grading system based on NIR reflectance method, which consists of photodiode-array sensor, quartz-halogen lamp and fiber optic diverged two bundles for transmitting the light and detecting the reflected light, was developed and evaluated. It was possible to predict the soluble solid contents of peaches in real time and nondestructively using the system which had the accuracy of 91 percentage and the capacity of 7,200 peaches per an hour for grading 2 classes by sugar contents. Draining is one of important factors for production peaches having good qualities. The reason why one farm's product belows others could be estimated for bad draining, over-much nitrogen fertilizer, soil characteristics, etc. After this, the report saved by the peach grading system will have to be good materials to farmers for production high quality peaches. They could share the result or compare with others and diagnose their cultural practice.

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Gas dynamics and star formation in NGC 6822

  • Park, Hye-Jin;Oh, Se-Heon;Wang, Jing;Zheng, Yun;Zhang, Hong-Xin;de Blok, W.J.G.
    • The Bulletin of The Korean Astronomical Society
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    • v.46 no.2
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    • pp.70.2-71
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    • 2021
  • We examine gas kinematics and star formation activities of NGC 6822, a gas-rich dwarf irregular galaxy in the Local Group at a distance of ~490 kpc. We perform profile decomposition of all the line-of-sight (LOS) HI velocity profiles of the high-resolution (42.4" × 12" spatial; 1.6 km/s spectral) HI data cube of the galaxy, taken with the Australian Telescope Compact Array (ATCA). To this end, we use a novel tool based on Bayesian Markov Chain Monte Carlo (MCMC) techniques, the so-called BAYGAUD, which allows us to decompose a velocity profile into an optimal number of Gaussian components in a quantitative manner. We group all the decomposed components into bulk-narrow, bulk-broad, and non-bulk gas components classified with respect to their velocity dispersions and the amounts of velocity offset from the global kinematics, respectively. Using the surface densities and velocity dispersions of the kinematically decomposed HI gas maps together with the rotation curve of NGC 6822, we derive Toomre-Q parameters for individual regions of the galaxy which quantify the level of local gravitational instability of the gaseous disk. We also measure the local star formation rate (SFR) of the corresponding regions in the galaxy by combining GALEX Far-ultraviolet (FUV) and WISE 22㎛ images. We then relate the gas and SFR surface densities in order to investigate the local Kennicutt-Schmidt (K-S) law of gravitationally unstable regions which are selected from the Toomre Q analysis. Of the three groups, the bulk-narrow, bulk-broad and non-bulk gas components, we find that the lower Toomre-Q values the bulk-narrow gas components have, the more consistent with the linear extension of the K-S law derived from molecular hydrogen (H2) observations.

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Gas kinematics and star formation in NGC 6822

  • Park, Hye-Jin;Oh, Se-Heon;Wang, Jing;Zheng, Yun;Zhang, Hong-Xin;de Blok, W.J.G.
    • The Bulletin of The Korean Astronomical Society
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    • v.45 no.1
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    • pp.61.4-62
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    • 2020
  • We present H I gas kinematics and star formation activities of NGC 6822, a dwarf galaxy located in the Local Volume at a distance of ~490 kpc. We perform profile decomposition of the line-of-sight velocity profiles of the high-resolution (~42.4" × 12") spatial; ~1.6 km/s spectral) H I data cube taken with the Australia Telescope Compact Array (ATCA). For this, we use a new tool, the so-called BAYGAUD (BAYesian GAUssian Decompositor) which is based on Bayesian Markov Chain Monte Carlo (MCMC) techniques, allowing us to decompose a line-of-sight velocity profile into an optimal number of Gaussian components in a quantitative manner. We classify the decomposed H I gas components of NGC 6822 into kinematically cold, warm or hot ones with respect to their velocity dispersion: 1) cold: < 4 km/s, 2) warm: 4 ~ 8 km/s, 3) hot: > 8 km/s. We then derive the Toomre-Q parameters of NGC 6822 using the kinematically decomposed H I gas maps. We also correlate their gas surface densities with the surface star formation rates derived using both GALEX far-ultraviolet and WISE 22 micron data to examine the impact of gas turbulence caused by stellar feedback on the Kennicutt-Schmidt (K-S) law. The kinematically cold component is likely to better follow the linear extension of the Kennicutt-Schmidt (K-S) law for molecular hydrogen (H2) at the low gas surface density regime where H I is not saturated.

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Influences of the Defective Piezo-Elements of a Medical Ultrasonic Probe on Transient Acoustic Fields and B-Mode Images (의료용 초음파프로브의 압전소자 결함이 과도음장과 B-모드 영상에 미치는 영향)

  • Choi, Kwang-Yoon;Ha, Kang-Lyeol;Kim, Moo-Joon;Kim, Jung-Soon;Yang, Jeong-Hwa;Kang, Gwan-Suk;Choi, Min-Joo
    • The Journal of the Acoustical Society of Korea
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    • v.29 no.8
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    • pp.476-482
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    • 2010
  • The ultrasonic transient fields and B-mode images of a point target which were simulated for a medical ultrasonic probe with a few defective piezo-elements were compared with those for a normal probe. The present study considered a 3.5 MHz linear array probe whose acoustic beam was formed by the 64 active elements of total 192 elements. The results showed that the maximum amplitude and -3 dB width of the acoustic fields by main-lobes decreased linearly as the defective element number increased from one to four. However, the depths of foci remained almost unchanged, and the pressure differences between main-lobes and side-lobes tended to decrease due to rise in pressures in side-lobes. Such changes in ultrasonic fields affected the B-mode images of point targets. So the artifacts were formed in the right and left side of the target, and the lateral spatial resolutions were decreased while the axial resolution was almost the same.

Experimental Investigation of Characteristics Change by Kerf-Fill Material between Arrayed Elements of a Piezoelectric Transducer (압전 배열 트랜스듀서의 진동 요소간 kerf 충진 매질에 따른 특성변화의 실험적 고찰)

  • Kim, Jung-Soon;Kim, Moo-Joon;Ha, Kang-Lyeol
    • The Journal of the Acoustical Society of Korea
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    • v.27 no.5
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    • pp.215-220
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    • 2008
  • The kerfs between arrayed piezoelectric elements in a medical ultrasonic transducer or a piezoelectric composite transducer are generally filled by polymeric materials. The boundary condition of the elements for lateral mode vibration is changed according to the kerf-filling materials, so that the resonance frequency for longitudinal mode of the transducer is also varied. In this study, to investigate the resonance frequency variation for an arrayed transducer experimentally, the piezoelectric vibration elements of $14mm{\times}0.22mm{\times}0.44mm$ were fabricated and those were linearly arrayed. And, the resonance frequencies were measured for three cases of kerf-filling condition, non-filling and two different kinds of epoxy filling. Conclusively, it is confirmed that the resonant frequency variation shows the similar tendency with the theoretical one for the longitudinal mode.