• Title/Summary/Keyword: Limited-disease

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Trunk Injection of Citrus Trees with a Polymeric Nanobactericide Reduces Huanglongbing Severity Caused by Candidatus Liberibacter asiaticus

  • Ramiro Guerrero-Santos;Gabriela Cabrales-Orona;John Paul Delano-Frier;Judith Cabello-Romero;Jose Roman Torres-Lubian;Jose Humberto Valenzuela-Soto
    • The Plant Pathology Journal
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    • v.40 no.2
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    • pp.139-150
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    • 2024
  • Huanglongbing (HLB) is a disease caused by the phloem-limited Candidatus Liberibacter asiaticus (CLas) that affects the citrus industry worldwide. To date, only indirect strategies have been implemented to eradicate HLB. Included among these is the population control of the psyllid vector (Diaphorina citri), which usually provides inconsistent results. Even though strategies for direct CLas suppression seem a priori more promising, only a handful of reports have been focused on a confrontation of the pathogen. Recent developments in polymer chemistry have allowed the design of polycationic self-assembled block copolymers with outstanding antibacterial capabilities. Here, we report the use of polymeric nano-sized bactericide particles (PNB) to control CLas directly in the phloem vasculature. The field experiments were performed in Rioverde, San Luis Potosí, and is one of the most important citrusproducing regions in Mexico. An average 52% reduction in the bacterial population was produced when PNB was injected directly into the trunk of 20 infected trees, although, in some cases, reduction levels reached 97%. These results position PNB as a novel and promising nanotechnological tool for citrus crop protection against CLas and other related pathogens.

A Clinical Therapeutic Results on Small Cell Lung Cancer (소세포 폐암의 치료성적에 대한 고찰)

  • Kim, Eun-Hwa;Lee, Soon-Hyoung;Huh, Won-Young;Kim, Han-Sik;Jo, Jin-Ung;Kim, Mee-Ae;Kim, Sang-Kyun;Kim, Kwi-Wan;Chung, Weon-Kuu;Kim, Soo-Kon
    • Tuberculosis and Respiratory Diseases
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    • v.41 no.3
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    • pp.262-269
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    • 1994
  • Background : A clinical study was carried out on 153 new cases with small cell lung cancer registered at Presbyterian Medical Center, Chonju during the 7 years from 1986 to 1992. They were analyzed by sex and age distribution, symptoms and signs, classification of stage and site and its treatments. Especially, an effort was made to compare the overall survival time between limited stage and extensive stage. Methods : Among 806 lung cancer patients diagnosed by biopsy or cytologic evaluation for the 7 years, 153 patients was shown small cell lung cancer. These 153 cases was analyzed retrospectivery through patient's records, letters or telephones. Results : The results of evaluation of small cell lung cancer are as follows. Over 85 percent of the small cell lung cancer patients were over 50 years of age and prominent clinical features were cough(86.3%), sputum(75.8%) and dyspnea(54.9%). One hundred and five patients(68.7%) was staged to have limited stage. Mean survival time of the chemotherapy and chemoradiotherapy in limited stage has significant difference and its survivals are 5.3 months and 15.0 months. Patients whose disease was staged as limited, regardless of whether or not chemotherapy was administered, had a median survival time of 10.9 months, compared with 4.8 months for those with extensive stage. Conclusion : Lung cancer is one of the malignant diseases tend to increase gradually in Korea and proven to be the most common cancer next to the gastric cancer among various cancers in males found at the Presbyterian Medical Center in the past seven years. This report is a retrospective view of the clinical therapeutic results of the small cell lung cancer patients. Especially at the limited stage, the combined therapy revealed higher survival rate than the chemotherapy alone. For a more accurate evaluation. a prospective view, without any bias, of patients selected at random is needed.

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Epidemiological Patterns of Cancer Incidence in Southern China: Based on 6 Population-based Cancer Registries

  • Liu, Jie;Yang, Xu-Li;Li, Ai;Chen, Wan-Qing;Ji, Lu;Zhao, Jun;Yan, Wei;Chen, Yi-Ying;Zhu, Li-Ping
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.3
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    • pp.1471-1475
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    • 2014
  • Background: The epidemiological patterns of cancer incidence have been investigated widely in western countries. Nevertheless, information is quite limited in Jiangxi province, southern China. Materials and Methods: All data were reported by 6 population-based cancer registries in Jiangxi Province. The results were presented as incidence rates of cases by site (ICD-10), sex, crude rate (CR), age-standardized rates (ASRs) and truncated incidence rate (TR) per 100,000 person-years, using the direct method of standardization to the world population. Results: 8,765 new cancer cases were registered in our study during the period 2009-2011. Diagnosis of cancer was based on histopathology in 61.0%, clinical or radiology findings in 4.87% and death certificate only (DCO) in 3.0% of the cases. The median age at diagnosis was 62.0 years (mean, 61; standard deviation, 15). The ASRs were 170.8 per 100,000 for men and 111.2 for women. The ASRs for all invasive cancers from the urban areas (145.7 per 100,000) was higher than that of rural areas (137.1). Incidence rates for lung cancer were higher in rural (35.8) than in urban areas (27.0). Similarly, relatively high rates were observed for stomach cancer in rural (20.1) relative to urban areas (15.5). Conclusions: Our results reveal that the most common cancers were breast and lung in women and lung and liver in men. Interestingly, this study suggested a higher incidence rates for lung and stomach cancer in rural males than in urban population, which may suggest other potential causes, such as over-consumption of smoked meats and high prevalence of Helicobacter pylori infection, respectively. Public education and the promotion of healthy lifestyles should be actively carried out.

Diagnosis of Work-related Musculoskeletal Disease through Moire Image Pattern and Treatment Measure using a Sling System (Moire' 영상무늬를 통한 근골격계질환의 진단과 현가장치를 이용한 치료방안)

  • Lee Sang-Yong;Lee Eun-Kyong;Kwon So-Hee;Jung He-Kyong;Kim Sam-Tae;Chong Myong-Soo;Lee Ki-Nam
    • Journal of Society of Preventive Korean Medicine
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    • v.7 no.2
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    • pp.121-130
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    • 2003
  • The Musculoskeletal Disease has been ignored or turned away due to the difficulty of diagnosis and the vagueness of judgement up to now. Contrary to other diseases, there were many cases where the character of the Musculoskeletal Disease wasn't revealed through the objective inspection. And that's because the Musculoskeletal Disease appears for the most part due to muscular defect so it is impossible to diagnose the muscle by X-ray diagnosing the bone and it is also impossible to diagnose the fine damage of the muscle or tendon even by advanced device like MRI. As the nervous blood vessels or acupunctures pass through or are next to the muscle, the tension of the muscle put pressure on these so can become the direct or indirect causes of various kinds of pains or intern diseases. But in spite of that, for lack of proper equipment diagnosing the state of the muscle(Shortened.. Relaxed... or Hardened...) the muscle has been disregarded or neglected intentionally or unintentionally. While many people think themselves to be a muscular expert, if they don't see the shape of the muscle, that is just like blind treatment. But as now the equipment diagnosing the state of the muscle is developed, it seems that this problem can be settled. It was attempted in this study that the muscle or skeleton of the Musculoskeletal disease patients was diagno the treatment order and method were decided by a questionnaire survey and simple inspection, and the Musculoskeletal correction exercise using the muscle management and sling system made them escape from the Musculoskeletal disease, turning their muscle into more flexible and stronger muscle. As a result notwithstanding the limited treatment period '12 times', the improvement rate was as high as 74%, which showed that the muscle management and Musculoskeletal correction exercise had a great effect on the symptom improvement of the patients. If the treatment times had increased, the improvement rate also would have increased more.

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A Case of Korean Medical Treatment on Parkinson's Disease Patient with Postural Instability, Presenting as Camptocormia (몸통굽힘증을 주소로 하는 파킨슨병 환자의 자세 이상에 대한 한의 치료 증례 1례)

  • Kim, Ha-ri;Jeong, Hye-seon;Shin, Hee-yeon;Choi, Jeong-woo;Yang, Seung-bo;Cho, Seung-yeon;Park, Jung-mi;Ko, Chang-nam;Park, Seong-uk
    • The Journal of Internal Korean Medicine
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    • v.40 no.2
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    • pp.220-227
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    • 2019
  • Objectives: Parkinson's disease is the neurodegenerative disease that affects both motor and non-motor function, including postural instability. Camptocormia is an abnormal condition in which the thoracolumbar spine bends forward during walking or standing. However, the treatment options are limited and often not effective. The purpose of this study was to report on the Korean medical treatment of a Parkinson's disease patient with postural instability who presented with camptocormia. Methods: We used Korean medical treatment including herbal medicine (Jemageopung-tang), acupuncture and pharmacopuncture therapy to the patient who was admitted to the hospital for 21 days. The clinical symptoms were assessed with the Unified Parkinson's Disease Rating Scale (UPDRS) and walking time without assistance. Results: After treatment, the UPDRS Parts 2 and 3 scores were decreased from 5 to 3 and 20 to 9, respectively. Also, the walking time without assistance was improved. Conclusion: This study suggested that Korean medical treatment could be an effective option for treating Parkinson's disease with postural instability.

An Analysis Model Study on the Vulnerability in the Infectious Disease Spread of Public-use Facilities neighboring Senior Leisure Welfare Facilities (노인여가복지시설 주변 다중이용시설에서의 감염병 확산 취약성 분석 모델에 관한 연구)

  • Kim, Mijung;Kweon, Jihoon
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.28 no.4
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    • pp.41-50
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    • 2022
  • Purpose: This study aims to suggest an analysis model finding the relationship between building scale characteristics of Public-use facilities and infectious disease outbreaks around senior leisure welfare facilities and the features and their scopes where quarantine resources are to be concentrated. Methods: Reviewing previous studies found the user characteristics of senior leisure welfare facilities and scale characteristics of urban architectures. The data preprocessing was performed after collecting building data and infectious disease outbreak data in the analysis area. This study derived data for attributes of building size and frequency of infectious disease outbreaks in Public-use facilities around senior leisure welfare facilities. A computing algorithm was implemented to analyze the correlation between the building size characteristics and the infectious disease outbreak frequency as per the change of the spatial scope. Results: The results of this study are as follows: First, the suggested model was to analyze the correlation between the infection frequency and the number of senior leisure welfare facilities, the number of Public-use facilities, building area, total floor area, site area, height, building-to-land ratio, and floor area ratio varied as per the change of spatial scope. Second, correlation results varied between the infection frequency and the number of senior leisure welfare facilities, the number of Public-use facilities, building area, total floor area, site area, height, building-to-land ratio, and floor area ratio. Third, a negative correlation appeared in the analysis between the number of senior leisure welfare facilities and infection frequency. And positive correlations appeared noticeably in the study between the number of Public-use facilities, building area, total floor area, height, building-to-land ratio, and floor area ratio. Implications: This study can be used as primary data on the utilization of limited quarantine resources by analyzing the relationship between the Public-use facilities around the senior leisure welfare facilities and the spread of infectious diseases. In addition, it suggests that infectious disease prevention measures are necessary considering the spatial scope of the analysis area and the size of buildings.

A Study on Beauty Artistis' the Morbidity of Limited Range of Motion about Cervical and the Factors Related to the Disease (미용사들의 경견완장애 자각증상에 대한 실태조사에 관한 연구)

  • 김양순;김은숙
    • Korean Journal of Health Education and Promotion
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    • v.19 no.1
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    • pp.185-197
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    • 2002
  • This study was conducted to analyze the factors affected morbidity for beauty artists of the limited range of motion about cerviacl, shoulder and wrist, from July 15 through August 30, 2000. Questionnaires were distributed to 373 beauty artists working in beauty shops of Taegu city. The factors included general characteristics, working conditions, life style and regular diagnosis of subject. The data collected were analyzed by SPSS program and the results of this study are summarized as follows; By the marital status, 224(86.5%) out of 259 unmarried beauty artists had the complaint of a neck(P〉0.05), and by the status of education, the complaint rate of a shoulder of beauty artists who graduated university(92.9%) is the highest(P〈0.01). In survey of complaint rates of symptom by the sleeping place, 324(86.7) out of 373 subjects had the pain in shoulder(P〈0.01), specially, beauty artists who are sleeping in bed complained the pain in shoulder more the others, in survey of complaint rates of symptom by sleeping pose, there was the significant different in neck(P〈0.01) and shoulder(P〈0.001). In survey of complaint rates of symptom by regular diagnosis, 61(85.9%) out of 71 beauty artists who took regular diagnosis and 263(87.4%) out of 302 beauty artists who didn't take regular diagnosis(P〈0.05). In conclusion, beauty artists who are on their feet for long time by official trait complaint the pain in neck and shoulder mainly. This result occurs from complex action of general characteristics and work condition and so on. In order to promote the health of beauty artists, there are needs for moderate exercise and regular diagnosis.

Teachers' Negative Attitudes and Limited Health Literacy Levels as Risks for Low Awareness of Epilepsy in Turkey

  • Gulay Yilmazel
    • Journal of Preventive Medicine and Public Health
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    • v.56 no.6
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    • pp.573-582
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    • 2023
  • Objectives: For students with epilepsy, schools are a critical environment for managing the disease properly. This study examined awareness of epilepsy, attitudes toward epilepsy, and health literacy among school teachers in Turkey. Methods: This study was conducted in a city in Turkey with 1408 public school teachers from June 2021 to September 2021. Results: The median scores of the scales were 5, 29, and 32 for epilepsy awareness, epilepsy attitudes, and health literacy, respectively. Epilepsy awareness was higher in women, and epilepsy attitudes were more positive in women than men (p<0.05). While epilepsy awareness was higher in primary school teachers, epilepsy attitudes were more positive in secondary school teachers (p<0.05). Epilepsy awareness was lower in secondary school teachers (odds ratio [OR], 1.27; p<0.05), those who did not have an individual with epilepsy in their family/social environment (OR, 1.57; p<0.001), those who did not have a student with epilepsy in their class (OR, 1.45; p<0.05), and in those who had not witnessed an epilepsy seizure (OR,1.19; p<0.05). Compared to those with positive attitudes regarding epilepsy, epilepsy awareness was 1.36 times lower in those with negative attitudes (p<0.001). Epilepsy awareness was 1.92 times lower in those with limited health literacy than those with adequate health literacy (p<0.001). Conclusions: In this study, low epilepsy awareness, negative epilepsy attitudes, and limited health literacy were common among teachers. The findings from this study suggest that panels, workshops, and health training on epilepsy should be organized for school teachers and included at regular intervals in certified first-aid practices.

Pancreas-preserving limited duodenal resection: Minimizing morbidity without compromising oncological adequacy

  • Ajay Sharma;Anand Nagar;Peeyush Varshney;Maunil Tomar;Shashwat Sarin;Rajendra Prasad Choubey;V. K. Kapoor
    • Annals of Hepato-Biliary-Pancreatic Surgery
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    • v.26 no.2
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    • pp.149-158
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    • 2022
  • Backgrounds/Aims: Pancreaticoduodenectomy is the most common procedure for the management of duodenal pathologies. However, it is associated with substantial morbidity and a low risk of mortality. Pancreas-preserving limited duodenal resection (PPLDR) can be performed under specific scenarios. We share our experience with PPLDR and its outcome. Methods: We retrospectively analyzed a prospectively maintained database of patients undergoing limited duodenal resection in the form of wedge (sleeve) resection or segmental resection of one or more duodenal segments from March 2016 to March 2021 at a tertiary care center in North India. Results: During the study period, 10 patients (including 9 males) underwent PPLDR. Five of these 10 patients showed primary duodenal or proximal jejunal pathology, while the remaining five had duodenal pathology involving an adjacent organ tumor. Four patients underwent wedge (sleeve) resection, while the remaining six underwent segmental duodenal resection of one or more duodenal segments. Mean hospital stay was 6 days (range, 3-11 days) without 30-day mortality. Morbidity occurred in 4 patients (Grade I-II, n = 3; Grade III, n = 1). All patients were alive and disease-free at the time of last follow-up. The mean follow-up duration was 23 months (range, 2-48 months). Conclusions: PPLDR is a safe and effective alternative for pancreaticoduodenectomy when selected carefully for specific tumor types and location.

Status and related factors of private health insurance for severely ill patients (중증질환자의 민간의료보험 가입 현황 및 관련요인)

  • Kim, Seok-Hwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.1
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    • pp.497-505
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    • 2018
  • This study was conducted to investigate the characteristics of private health insurance subscribers and non-subscribers as they relate to severely ill patients, and to identify the factors of participation. The study was conducted using the National Health and Nutrition Examination Survey for 2015, and data were analyzed using SPSS ver. 23.0. The subjects were 417 patients with severe disease (cancer, heart disease, cerebrovascular disease) over 19 years of age. Crossover analysis was employed to identify differences between the state of private health insurance participation, while binary logistic regression analysis was used to confirm the factors affecting private health insurance subscription. Analysis of the effects of the subjects on the private health insurance participation rate revealed that the social and demographic characteristics were higher in younger individuals regardless of sex, residence, or marital status. Moreover, higher household income, regardless of the education level, was associated with a higher participation rate of health insurance target individuals compared to medical benefit target individuals. The private health insurance participation rate was low and the explaining power was 51.7%, regardless of subjective health awareness and walking practice. Therefore, efforts should be made to improve the living environment and support local governmental programs for the elderly, low income households, socially vulnerable groups with limited activities and groups with limited health behavior. It is also necessary to consider various health policies, such as providing government health education or programs to prevent severe illness.