• Title/Summary/Keyword: Limited Stage

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Outcome of Limited Resection for Lung Cancer

  • Cho, Jeong-Su;Jheon, Sang-Hoon;Park, Sung-Joon;Sung, Sook-Whan;Lee, Choon-Taek
    • Journal of Chest Surgery
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    • v.44 no.1
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    • pp.51-57
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    • 2011
  • Background: Up to now, lobectomy, bilobectomy and pneumonectomy combined with extensive lymph node dissection have been regarded as the standard procedures for non-small cell lung cancer (NSCLC). In high-risk patients, however, limited resection (LR) has been attempted as a salvage procedure, and, recently, indication for LR has been extended to selected cases with early-stage NSCLC. Material and Methods: Among the 773 patients who underwent surgical procedures for NSCLC in Seoul National University Bundang Hospital from May 2003 to December 2008, 43 patients received LR. Medical records of these patients were retrospectively reviewed. Results: Mean age at operation was $66.0{\pm}12.4$ years, and there were 30 males. Twenty-five patients underwent conservative limited resection (CLR) and 18 underwent intentional limited resection (ILR). Indications for CLR were multiple primary lung cancer in 9 (9/25, 36%) and severe concomitant diseases in 5 (5/25, 20%). Of these, 6 patients underwent segmentectomy and 19 received wedge resection. During the follow-up period of $28.0{\pm}17.8$ months, 15 patient developed recurrent lung cancer. ILR was selectively performed in lesions almost purely composed of ground glass opacity (${\geq}$95%), or in small solid lesions (${\leq}$2 cm). Of these, 11 patients underwent segmentectomy and 7 underwent wedge resection. During the follow-up period of $31.7{\pm}11.6$ months, no patient developed recurrence. Conclusion: Intermediate-term outcome of LR for early-stage lung cancer is comparable to that of standard operation. For the delineation of the indications and appropriate surgical techniques for LR, prospective randomized multi-institutional study may be expedient.

ESTIMATING COSTS DURING THE INITIAL STAGE OF CONCEPTUAL PLANNING FOR PUBLIC ROAD PROJECTS: CASE-BASED REASONING APPROACH

  • Seokjin Choi;Donghoon Yeo;Seung H. Han
    • International conference on construction engineering and project management
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    • 2009.05a
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    • pp.1183-1188
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    • 2009
  • Estimating project costs during the early stage of conceptual planning is very important when deciding whether to approve the project and allocate an appropriate budget. However, due to greater uncertainties involved in a project, it is challenging to estimate costs during this initial stage within a reasonable tolerance. This paper attempts to develop a cost-estimate model for public road projects under these circumstances and limitations. In the conceptual planning stage of a road project, there is only limited information for cost estimation, for example, such input data as total length of the route, origin and destination, number of lanes, general geographic characteristics of the route, and other basic attributes. This implies that the model should individuate suitable but restricted information without considering detailed features such as quantity of earthwork and a detailed route of a given condition. With these limited facts, this paper applies a case-based reasoning (CBR) method to solve a new problem by deriving similar past problems, which in turn is used to estimate the cost of a given project based on best-fitted previous cases. To develop a CBR cost-estimate model, the authors classified 8 representative variables, including project type, the number of lanes, total length, road design grades, etc. Then, we developed the CBR model, primarily by using 180 actual cases of public road projects, procured over the last decade. With the CBR model, it was found that the degree of error in estimation can be reasonably reduced, to below approximately 30% compared to the final costs estimated upon the completion of detailed design.

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Effects of Sowing and Harvesting Time on Feed Value and Quality of Triticale (X Triticosecale Wittmack)

  • Jisuk Kim;Kyungyoon Rha;Myoung Ryoul Park;Yul-Ho Kim
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.144-144
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    • 2022
  • The amount of required forage is increasing by 20% every year in South Korea, but the cultivation area for forage production is limited. The yield ability of triticale forage is the highest among the winter forage crops including rye and the crop has cold tolerance within the average low temperature of -10℃ in January. Therefore, this study analyzed effects of sowing and harvesting times on feed value and quality for efficiently using and supplying triticale as livestock feed. Seed of the triticales, 'Joseong' was sown in 2021 fall (October) and 2022 spring (March). The triticales were harvested according to growth stages: seedling stage, booting stage, heading stage, 10 days after heading, and 20 days after heading. Moisture contents of each harvested triticales were adjusted to about 60%, and then the triticales were fermented for 40 days at room temperature under anaerobic conditions as silage. We have analyzed pH and organic acid to determine the feed value and quality of each silage. The contents of lactic acid in silage ofthe triticale harvested at the seedling stage of both fall and spring-sown (1.61%, 1.63%) were the highest among all of the silages; the booting stage (0.75%, 1.33%), the heading stage (0.50%, 0.69%), 10 days after the heading stage (0.31%, 0.42%), and 20 days after heading stage (0.22%, 0.40%). Such as the contents of lactic acid in the silages, and the pH value of the silages The pH value in both the fall- and spring-sown became lower as the triticale was grown up: seedling stage (7.05, 6.85), booting stage (6.21, 6.75), heading stage (6.18, 6.28), 10 days after heading stage (6.22, 6.17), and 20 days after heading stage (6.15, 5.81). Taken together, the results showed that the feed value and quality of triticale silage were more affected by harvesting time than sowing time.

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G Protein Mediated Hatching Regulation in the Mouse Embryo

  • Cheon, Yong-Pil
    • Development and Reproduction
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    • v.16 no.1
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    • pp.69-75
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    • 2012
  • Hatching occurred in the time dependent manners and strictly controlled. Although, the hatching processes are under the control of muti-embryotrophic factors and the expressed G proteins of cell generate integrated activation, the knowledge which GPCRs are expressed during hatching stage embryos are very limited. In the present study, which G proteins are involved was examined during blastocyst development to the hatching stage. The early-, expanded-, and lobe-stage blastocysts were treated with various $G_{\alpha}$ activators and H series inhibitors, and examined developmental patterns. Pertusis toxin (PTX) improved the hatching rate of the early-stage blastocyst and lobe-formed embryos. Cholera toxin (CTX) suppressed the hatching of the early-stage blastocyst and expanded embryos. The effects of toxins on hatching and embryo development were changed by the H7 and H8. These results mean that PTX mediated GPCRs activation is signaling generator in the nick or pore formation in the ZP. In addition, PTX mediated GPCR activation induces the locomotion of trophectoderm for the escaping. CTX mediate GPCRs activation is the cause of suppression of hatching processes. Based on these data, it is suggested that various GPCRs are expressed in the periimplantation stage embryos and the integration of the multiple signals decoding of various signals in a spatial and temporal manner regulate the hatching process.

Lloyds Register Asia Rail Systems Reliability Lifecycle Management

  • Jonathan, Bouchard
    • Proceedings of the KSR Conference
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    • 2003.10a
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    • pp.27-43
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    • 2003
  • Reliability Lifecycle from Concept to In-Service Operation and Maintenance. Reliability management must consider - SAFETY - SERVICE REQUIREMENTS. Reliability targets/objectives can be specified at feasibility stage. Reliability analysis to support design process. Reliability assessment to support reliability growth or contractual demonstration. Maintenance optimisation to improve reliability during lifetime of operation. Lessons learnt incorporated into next generation of trains.

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A Study on the Production System of Korean Stage Costume - Focused on the Musical 'Chicago' - (국내 무대의상 제작시스템 방법론 정립에 관한 연구 - 뮤지컬 '시카고'를 중심으로 -)

  • Kim, Young-Sam
    • Journal of the Korean Society of Costume
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    • v.62 no.4
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    • pp.1-14
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    • 2012
  • Ever since the year 2000, Korea's musical markets has invited famous overseas license performances and have therefore cooperated with staffs working overseas in regards to stage costumes. This study aims to suggest the methodology of the stage costume making process according to the present advanced production system of Korea's musical market. The researcher participated in the stage costume making work of 'Chicago' as a costume supervisor. It took place at the Opera House of Seongnam Art Center from January 10, 2010 to February 28, 2010. Furthermore, there was significance in reinforcing academic values and implementing practical making process of stage-costumes based on the actual field work. The method of this research was carried out through a theoretical research and a case study that focused on empirical research. As for the research scope, it was limited to the actual stage-costumes that the researcher fully engaged with as a costume supervisor of the musical 'Chicago.' The results of this study were as follows. The stage costume making process of the musical 'Chicago' was categorized according to the classification of production system in the performance. For pre-production, it was divided according to the information of the actor and the analysis of the bible. Rehearsal period was divided according to the product clothes and fitting. Production week & preview were divided according to the changeover of clothes and the arrangement of dressers. The Run was divided according to the inspection of the situation concerning clothes in general during the performance. Post-Production Period was divided according to the collection of clothes and the implemented database. This study eventually suggested appropriate stage-costume making processes for the costumes making environment according to the expansion of overseas license musical market. However, it has a limitation of the research scope to the musical 'Chicago.' The creative performances of the domestic version are planned in diverse forms and come to abroad animate by the Korean Wave. Therefore, the field of stage-costume is necessary for the establishment of practical schemes of the system and copyright in accordance with the environment.

A Study on Predicting Construction Cost of School Building Projects Based on Support Vector Machine Technique at the Early Project Stage (Support Vector Machine을 이용한 교육시설 초기 공사비 예측에 관한 연구)

  • Shin, Jae-Min;Park, Hyun-Young;Shin, Yoon-Seok;Kim, Gwang-Hee
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2012.11a
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    • pp.153-154
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    • 2012
  • The accuracy of cost estimation at an early stage in school building project is one of the critical factors for successful completion. So many method and techniques have developed that can estimate construction cost using limited information available in the early stage. Among the techniques, Support Vector Machine(SVM) has received attention in various field due to its excellent capacity for self-learning and generalization performance. Therefore, the purpose of this study is to verify the applicability of cost prediction model based on SVM in school building project at the early stage. Data used in this study are 139 school building cost constructed from 2004 to 2007 in Gyeonggi-Do. And prediction error rate of 7.48% in support vector machine is obtained. So the results showed applicability of using SVM model for predicting construction cost of school building projects.

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