• Title/Summary/Keyword: Limited Life

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Future Opportunities for life Science Programs in Space

  • Hiroki Yokota;Sun, Hui-Bin;George M. Malacinski
    • Animal cells and systems
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    • v.4 no.3
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    • pp.239-243
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    • 2000
  • Most space-related life science programs are expensive and time-consuming, requiring international cooperation and resources with trans-disciplinary expertise. A comprehensive future program in "life sciences in space" needs, therefore, well-defined research goals and strategies as well as a sound ground-based program. The first half of this review will describe four key aspects such as the environment in space, previous accomplishments in space (primarily focusing on amphibian embryogenesis), available resources, and recent advances in bioinformatics and biotechnology, whose clear understanding is imperative for defining future directions. The second half of this review will focus on a broad range of interdisciplinary research opportunities currently supported by the National Aeronautics and Space Administration (NASA), National Institute of Health (NIH), and National Science Foundation (NSF). By listing numerous research topics such as alterations in a diffusion-limited metabolic process, bone loss and skeletal) muscle weakness of astronauts, behavioral and cognitive ability in space, life in extreme environment, etc., we will attempt to suggest future opportunities.

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Probabilistic Assessment of life Time for Gas Pipe Lines (통계적 방법을 통한 가스배관의 잔여수명 예측)

  • Choe, B.H.;Lee, S.H.;Kim, Y.P.;Kim, W.S.;Ko, Y.T.
    • Proceedings of the KSME Conference
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    • 2004.04a
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    • pp.234-239
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    • 2004
  • A study on the probabilistic methodology for the estimation of the remaining life of Pressurized pipelines containing active corrosion defects is presented. This reliability assessment is earned out using extream value distribution of the corroded defects instead of already published failure perssure moded like NG18 or ASME B31G. The failure probability of pipelines depends on the number of corroded defects. and it could be calculated directly as the area exceeded a defined L V(Limited Value of corrosion depth). The remaining life of pressurized pipelines can also be estimated by the PDF of extream value distribution as calculating the exceeded area with a defined failure probability.

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Change of Lifestyle by Changing Member of Family (가족 구성원의 변화에 따른 라이프스타일의 변천)

  • Lee, Nam-Sik;Suh, Kuee-Sook
    • Proceedings of the Korean Institute of Interior Design Conference
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    • 2007.11a
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    • pp.54-58
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    • 2007
  • The part of women was limited in a large family of the past and the benefit of a family was more valuable than the advantage of an individual. But social activity of the individual who is a member of the family is increased by the industrialization and rapid changes of society. As a result importance of the family is on the decrease in a society. All such phenomenons make new family types that we could not imagine at past and various life-style. This research proposes life-style of the near future and investigated by life-style stream process according to change members of the family with various documentary record. In conclusion, life-style of the near future is changed individualistic, rationalistic and material.

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Shelf Life Prediction for Packaged Produce Sensitive to Moisture Damage (수분손상에 민감한 포장된 제품의 저장수명 예측)

  • Lee, Chong-Hyun
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.4 no.1
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    • pp.23-32
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    • 1997
  • The change in moisture content of moisture sensitive products in moisture-semipermeable packages was investigated for the purpose of predicting the shelf life of a product-package combination. A mathematical model, and a computer program based on the physiochemical properties of the product and the moisture permeability of the package was developed. The moisture content for products in moisture-semipermeable packages was determined under various environmental conditions and the results were compared with the predicted values by means of the simulation model. These experimental studies demonstrated that the prediction of the change in moisture content of packaged products over time by the simulation model is accurate, within a practical range of temperature and relative humidity values. The developed semi-empirical model is considered to have applications in industry, since it provides product shelf life information for a range of temperature and relative humidity conditions, with a limited number of experimentally obtained data points.

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한정고장집단의 출하품질 보증을 위한 샘플링검사방식 설계

  • 권영일
    • Proceedings of the Korean Reliability Society Conference
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    • 2002.06a
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    • pp.275-279
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    • 2002
  • A Bayesian acceptance sampling plan for limited failure populations are developed. We consider a situation where defective products have short lifetimes and non-defective ones never fail during the technological life of the products. An acceptance criterion which guarantees the out going quality of accepted products is derived using the prior information on the quality of lots submitted for inspection. Numerical examples are provided.

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Phylogenetic Analysis of the HIV-1 nef Gene from Korean Isolates

  • Lee, Dong-Hun;Yeup Yoon;Lee, Chan-Hee
    • Journal of Microbiology
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    • v.41 no.3
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    • pp.232-238
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    • 2003
  • Previous phylogenetic studies on human immunodeficiency virus type 1 (HIV-1) isolated from Korean patients suggest that the major subtype of Korean isolate is subtype B. In this subtype, some of the Korean isolates seem to be clustered exclusively of foreign isolates. Presence of this so-called “Korean clade” among Korean isolates is unique but needs verification since the number of Korean isolates used in previous studies was limited. This study aimed to identify the presence of the “Korean clade” by molecular phylogenetic analysis using all the Korean nef gene sequences registered in the NCBI GenBank (N=243) together with 32 reference strains and 77 foreign isolates. Extensive analysis of the nef gene nucleotide sequences by neighbor-joining method revealed the following. Most (83.1 %) of the Korean isolates belonged to subtype B, and 81.2% of subtype B were clustered together and excluded foreign isolates (bootstrap value=91.9% ). Within Korean subtype B cluster, no characteristic subcluster formation was evident since the bootstrap values for the subcluster were very low. Due to limited information, the phylogenetic analysis failed to identify the epidemiological linkage among specific groups such as homosexuals and hemophiliacs within the Korean subtype B cluster. Detailed analysis and epidemiological information are needed to clarify the origin and significance of the Korean subtype B cluster.

Perspectives on high throughput phenotyping in developing countries

  • Chung, Yong Suk;Kim, Ki-Seung;Kim, Changsoo
    • Korean Journal of Agricultural Science
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    • v.45 no.3
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    • pp.317-323
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    • 2018
  • The demand for crop production is increasingly becoming steeper due to the rapid population growth. As a result, breeding cycles should be faster than ever before. However, the current breeding methods cannot meet this requirement because traditional phenotyping methods lag far behind even though genotyping methods have been drastically developed with the advent of next-generation sequencing technology over a short period of time. Consequently, phenotyping has become a bottleneck in large-scale genomics-based plant breeding studies. Recently, however, phenomics, a new discipline involving the characterization of a full set of phenotypes in a given species, has emerged as an alternative technology to come up with exponentially increasing genomic data in plant breeding programs. There are many advantages for using new technologies in phenomics. Yet, the necessity of diverse man power and huge funding for cutting-edge equipment prevent many researchers who are interested in this area from adopting this new technique in their research programs. Currently, only a limited number of groups mostly in developed countries have initiated phenomic studies using high throughput methods. In this short article, we describe the strategies to compete with those advanced groups using limited resources in developing countries, followed by a brief introduction of high throughput phenotyping.

The application of a Genetic Algorithm with a Chromosome Limited Life for the Distribution System Loss Minimization Re-configuration Problem (배전손실 최소화문제에서 개체수명을 고려한 유전적 알고리즘의 적용)

  • Choi, Dai-Seub;Lee, Myung-Un;Cho, Taek-Koo;Kim, Jong-Yung;Song, Min-Jong
    • Proceedings of the KIEE Conference
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    • 2002.07a
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    • pp.320-326
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    • 2002
  • Distribution system loss minimization re-configuration is 0-1 planning problem, and the number of combinations requiring searches is extremely large when dealing with typical system scales. For this reason, the application of a genetic algorithm (GA) seems attactive to solve this problem. Although Genetic algorithms are a type of random number search method, they incorporate a multi-point search feature and are therefore superior to one-point search techniques. The efficiency of GAs for solving large combinational problem has received wide attention. Further, parallel searching can be performed and the optimal solution is more easily reached. In this paper, for improving GA convergence characteristics in the distribution system loss minimization re-configeration problem, a chromosome "Limited Life" concept is intro duced. Briefly, considering the population homogenization and genetic drift problems, natural selection is achieved by providing this new concept, in addition to natural selection by fitness. This is possible because individuals in a population have an age value. Simulations were carried out using a model system to check this method's validity.

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Expression of Schizosaccharomyces pombe Thioltransferase and Thioredoxin Genes under Limited Growth Conditions

  • Cho, Young-Wook;Sa, Jae-Hoon;Park, Eun-Hee;Lim, Chang-Jin
    • BMB Reports
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    • v.34 no.5
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    • pp.395-401
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    • 2001
  • Schizosaccharomyces pombe gene encoding redox enzymes, such as thioltransferase (TTase) and thioredoxin (TRX), were previously cloned and induced by oxidative stress. In this investigation, their expressions were examined using $\beta$-galactosidase fusion plasmids. The expression of the two cloned genes appeared to be growth-dependent. The synthesis of $\beta$-galactosidase from the TTase-lacZ fusion was increased in the medium with the low glucose level, whereas it was significantly decreased in the medium without glucose or with galactose. It was also decreased in the nitrogen-limited medium. The synthesis of galactosidase from the TRX-lacZ fusion was unaffected by galactose or low glucose. However, it was lowered the absence of glucose. The synthesis of $\beta$-galactosidase from the TTase-lacZ fusion was shown to be enhanced in a higher medium pH. Our findings indicate that S. pombe TTase and TRX genes may be regulated by carbon and nitrogen sources, as well as medium pH.

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Primary School Teachers' Interest and Understanding of Bioethical Issues and Bioethics Teaching (생명윤리와 생명윤리교육에 대한 초등학교 교사의 인식 조사)

  • Park Inok;Park Jeeyoung;Cho Eun Hee;So Kyung-Hee;Kim Heui-Baik
    • Journal of Korean Elementary Science Education
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    • v.24 no.5
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    • pp.571-582
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    • 2005
  • This study aims to examine primary school teachers' interest and understanding of bioethical issues, and to analyze their perception of bioethics teaching in the primary school education. For this purpose, the questionnaires were constructed. The data were collected from 553 primary teachers in the whole country. Major findings of the studys are as follows. First, most primary school teachers showed high level of interest about bioethical issues, but they had the limited understanding about bioethical issues. Primary teachers showed the highest interest about' respect for human life' and the lowest understanding of 'awareness of current biotechnology' Second, the prior reasons why primary teachers wanted to teach specific bioethical issues in the classes were that 'they were closely related to social phenomena' and 'they were appropriate for enhancing students' awareness of the value of life'. Third, the lack of the teachers' knowledge about bioethics and limited supply of teaching materials were found to be barriers, which prevent them from teaching bioethical issues. The implications of these results are discussed for the improvement of bioethics teaching in primary school education.

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