• Title/Summary/Keyword: Limit Pressure

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Effect of L-Glutamic Acid and Paraben Solution on the Endothelial Cell Proliferation in the Glutaraldehyde- Fixed Bovine Pericardium (글루타르알데하이드 고정 소심 낭막에서의 내피세포 증식에 대한 글루탕산 및 파라벤용액의 효과)

  • Kim, Beom-Sik;Lee, Mun-Hwan;Yu, Se-Yeong;Kim, Won-Gon
    • Journal of Chest Surgery
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    • v.29 no.1
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    • pp.7-13
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    • 1996
  • The conventional glutaraldehyde (GA) fixation method of tissue valves is considered to be responsible for accelerated valve degeneration. The release of toxic GA from the valve tissue is believed to limit endothelial cell (EC) ingrowth. Removal of toxic GA by reaction with L-glutamic acid and storage in a Paraben solution may offer good EC growth. To investigate the conditions for endothelialization of tissue valves, the growth properties of ECs on the conventionally and alternatively treated pericardial tissue were compared. Conventional preparation included zero-pressure fixation for 72 hours in phosphated-buffered saline (PBS) solution containing 0.5% GA at 4$^{\circ}C$ and storage into PBS containing 0.2% GA(group I). Alternatively treated pericardial tissues were divided into three postfixation treatment groups : (1) storage in PBS solution containing Paraben(group II), (2) treatment with PBS containing 8$^{\circ}C$ L-glutamic acid(PH 7.35) and storage in PBS solution containing Paraben (g oup III), (3) treatment with L-glutamic acid dissolved in distilled water (PH 3.5) (group IV). Pericardial tissue were transferred into the 24-well plate after storage for 4 weeks. ECs were harvested enzymatically from the bovine pulmonary artery and grown to confluence on culture flask surfaces. Detached ECs by trypsin were incubated into the each well of the 24-well plate including test pericardial tissues. Cells were detached by trypsin, 1, 2, 3, 5, 7 days after incubation and counted on the hemacytometer. Cell viability test was performed by frypan-blue exclusion method. Acute cell death in the group I were found even after prolonged washing. The group II showed prolonged cell survival compared with the group I. Both group III and group IV showed better cell growth than group II. There was no statistically significant difference between group III and group IV method in terms of EC growth. This results suggest that treatment by L-glutamic ac id and storage in a Paraben solution be a promising approach for improvement of durability of GA-treated tissue valves.

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FMEA of Electrostatic Precipitator for Preventive Maintenance (전기집진기 예지보전 단계에서의 고장모드영향분석)

  • Han, Seung-Hun;Lee, Jeong-Uk;Lee, Sun-Youp;Hwang, Jong-Deok;Kang, Dae-Kon
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.26 no.6
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    • pp.706-714
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    • 2020
  • Currently, 90 % of the world's population breathes air with a fine dust content exceeding the World Health Organization's annual average exposure limit (10 ㎍/㎥). Global efforts have been devoted toward reducing secondary pollutants and ultra-fine dust through regulations on nitrogen oxides released over land and sea. Domestic efforts have also aimed at creating clean marine environments by reducing sulfur emissions, which are the primary cause of dust accumulation in ships, through developing and distributing environment-friendly ships. Among the technologies for reducing harmful emissions from diesel engines, electrostatic precipitator offer several advantages such as a low pressure loss, high dust collection efficiency, and NOx removal and maintenance. This study aims to increase the durability of a ship by improving equipment quality through failure mode effects analysis for the preventive maintenance of an electrostatic precipitator that was developed for reducing fine dust particles emitted from the 2,427 kW marine diesel engines in ships with a gross tonnage of 999 tons. With regard to risk priority, failure mode 241 (poor dust capture efficiency) was the highest, with an RPN of 180. It was necessary to determine the high-risk failure mode in the collecting electrode and manage it intensively. This was caused by clearance defects, owing to vibrations and consequent pin loosening. Given that pin loosening is mainly caused by vibrations generated in the hull or equipment, it is necessary to manage the position of pin loosening.

The Effect of Ankle Balance Training on Unstable and Stable Surface on Proprioception, Balance and Muscle Strength in Obese Middle-Aged Woman (불안정지지면과 안정지지면에서의 발목균형훈련이 비만중년여성의 고유수용성감각, 균형 및 근력에 미치는 영향)

  • Han, Jun Ho;Woo, Sunghee;Lee, Hyojeong
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2018.05a
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    • pp.580-583
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    • 2018
  • Purpose: The purpose of this study was to compare the effects of ankle balance training on unstable and stable surfaces to discover on which surface the proprioception, balance and muscle strength of obese middle aged women improves more. Method: 30 obese middle-aged women were randomly recruited and divided into two groups (training on an unstable surface, training on a stable surface). The subjects in each group participated in the training for six weeks, three times per week for 30 minutes each session. Proprioception was measured using Dualer IQ digital inclinometer; sway length (SL) and sway area (SA) of center of pressure, and limit of stability (LOS) were measured for balance; muscle strength before and after the training was measured using manual muscle testing. Results: There were significant improvements in the subscales of the proprioception, balance and muscle strength in those who participated in ankle balance training on the unstable surface, and in those who participated on the stable surface. Therefore, the training of participants on unstable and stable surfaces did not identify which ankle balance training technique was more effective. Conclusion: Unstable and stable surface ankle balance training are both effective in improving the proprioception, balance and muscle strength of obese middle-aged woman.

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Case Studies on Distributed Temperature and Strain Sensing(DTSS) by using an Optical fiber (광섬유 센서를 이용한 온도 및 변형 모니터링에 대한 현장응용 사례)

  • Kim, Jung-Yul;Kim, Yoo-Sung;Lee, Sung-Uk;Min, Kyoung-Ju;Park, Dong-Su;Pang, Gi-Sung;Kim, Kang-Sik
    • Proceedings of the Korean Geotechical Society Conference
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    • 2006.03a
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    • pp.86-95
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    • 2006
  • Brillouin backscatter is a type of reflection that occurs when light is shone into an optical fibre. Brillouin reflections are very sensitive to changes in the fibre arising from external effects, such as temperature, strain and pressure. We report here several case studies on the measurement of strain using Brillouin reflections. A mechanical bending test of an I beam, deployed with both fiber optic sensors and conventional strain gauge rosettes, was performed with the aim of evaluating: (1) the capability and technical limit of the DTSS technology for strain profile sensing; (2) the reliability of strain measurement using fiber optic sensor. The average values of strains obtained from both DTSS and strain gauges (corresponding to the deflection of I beam) showed a linear relationship and an excellent one-to-one match. A practical application of DTSS technology as an early warning system for land sliding or subsidence was examined through a field test at a hillside. Extremely strong, lightweight, rugged, survivable tight-buffered cables, designed for optimal strain transfer to the fibre, were used and clamped on the subsurface at a depth of about 50cm. It was proved that DTSS measurements could detect the exact position and the progress of strain changes induced by land sliding and subsidence. We also carried out the first ever distributed dynamic strain measurement (10Hz) on the Korean Train eXpress(KTX) railway track in Daejeon, Korea. The aim was to analyse the integrity of a section of track that had recently been repaired. The Sensornet DTSS was used to monitor this 85m section of track while a KTX train passed over. In the repaired section the strain increases to levels of 90 microstrain, whereas in the section of regular track the strain is in the region of 30-50 microstrain. The results were excellent since they demonstrate that the DTSS is able to measure small, dynamic changes in strain in rails during normal operating conditions. The current 10km range of the DTSS creates a potential to monitor the integrity of large lengths of track, and especially higher risk sections such as bridges, repaired track and areas at risk of subsidence.

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Analysis of Deformation and Stability of Slope at the Wiri Region of Local Road 999 Nearby Andong, Gyeongsangbukdo in Korea. (999번 지방도로 경상북도 안동시 위리 지역의 사면 변형 및 안정성 분석)

  • 장현식;장보안
    • The Journal of Engineering Geology
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    • v.10 no.1
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    • pp.1-12
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    • 2000
  • Heaving of road and subsidence of slope took place at the Wiri region of the local highway 999 in Gyeongsangbukdo, Korea after heavy rain in the next year of construction. Although the state government had performed remedial treatments by reducing the angle and the height of the slope, deformation had never stopped. Therefore, we have preformed the analysis of deformation and stabilityof the slope. Study area consists of the Cretaceous shale, siltstone and sandstone and two faults are found. The major deformation occurred by sliding of rock mass along faults after heavy rain because not only thepore pressure at the fault plane and the unit weight of sliding mass increased, but did the shearstrength of saturated fault clay become very low. The decrease in shear strength of saturated fault clayis the major factor among the reasons for deformation. Numerical simulations using limit equilibriummodel, finite difference model and finite element model were performed for eight cross sections.Although safety factors are above 1.7 during the dry season, they become below 1.0 when groundwaterlevel raises to surface. The maximum displacement is about 15-3Ocm. However, safety factors increasedto above 2.4 and the maximum displacement is below 2.08cm after remedial treatment, Indicating thatthe slope becomes stable.

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Evaluation of the Stability of Quay Wall under the Earthquake and Tsunami (지진 및 지진해일파 작용하의 해안안벽의 안정성평가)

  • Lee, Kwang-Ho;Ha, Sun-Wook;Lee, Kui-Seop;Kim, Do-Sam;Kim, Tae-Hyung
    • Journal of the Korean Geotechnical Society
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    • v.27 no.3
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    • pp.41-54
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    • 2011
  • The present study analyzes the stability of waterfront quay wall under the combined action of earthquake and tsunami. Adopting the limit equilibrium method, the stability of waterfront quay wall is checked for both the sliding and overturning. Forces due to tsunami are compared with the proposed formula and the 3-D one-field Model for immiscible TWO-Phase flows (TWOPM-3D). Variations of the stability of wall are also proposed by the parametric study including tsunami water height, horizontal seismic acceleration coefficient, internal friction angle of soil, friction angle between the wall and the soil and the pore water pressure ratio. The present study about the stability of wall is also compared with the case when earthquake and tsunami are not considered. As a result, the result of numerical analysis about the tsunami force is similar to that of proposed formula. When earthquake and tsunami are simultaneously considered, the stability of wall in passive case significantly decreases and tsunami forces in active case are affected as a resistance force on the wall and so the stability of wall increases.

Ion Exchange of Glutamic Acid Coupled with Crystallization (결정화 반응이 결합된 글루탐산의 이온교환)

  • 이기세
    • KSBB Journal
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    • v.11 no.5
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    • pp.606-612
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    • 1996
  • A specific ammino auid in a mixture can be crystallized inside an ion exchange column when displacer concentration is high enough to concentrate the amino acid in a pure band beyond its solubility limit. Glutamic acid formpd a discrete crystal layer in a cation exchanger column by operating displacement development mode and using a high concentration of displacer NaOH. The glutamic acid crystal formed was eluded from the column with the effluent stream and collected in a fraction collector. When 1.0 M of NaOH was used as a displacer, more than 60% of the loaded glutamic acid was recovered as crystal. The continuous crystallization and dissolution of crystal occurred, resulting in apparent movement of the crystal along the column without clogging or pressure increase. NaOH was proved a better displacer than NaCl because hydroxide ions neutralized hydrogen ions released from the resin and thus reduced the number of hydrogen ion competing with sodium ion for re-adsorption. The displacement development process coupled with crystallization provided higher concentration and recovery of glutamic acrid than conventional chromatography.

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Design on the large section of station tunnel under shallow overburden (저토피고 대단면 정거장터널의 설계)

  • Jeong, Yun-Young;Choi, Hae-Joon;Kim, Byung-Ju;Yu, Bong-Won;Kim, Yong-Il;Oh, Sung-Jin
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.9 no.2
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    • pp.171-182
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    • 2007
  • For minimizing the effect on the focus of civil traffic and environment conditions related to the excavation at the traffic jamming points, an underground station tunnel was planned with 35.5 m in length and bigger area than $200\;m^2$ in sedimentary rock mass. It faced the case that the overburden was just under 13 m. Not based on a pattern design but on the case histories of similar projects and arching effect, the design of large section tunnel under shallow overburden was investigated on three design subjects which are shape effect on the section area, application method of support pressure, and supporting and tunnel safety. According to the mechanical effect from section shape, a basic design and a preliminary design was obtained, and then supporting method of large section was planned by the supporting of NATM and a pipe roof method for subsidence prevention and mechanical stability. From the comparative study between both designs, it was found that the basic design was suitable and acceptable for the steel alignment of tunnel lining, safety and the design parameter restricted by the limit considered as partition of the excavation facilities. Through the analysis result of preliminary design showing the mechanical stability without stress concentration in tunnel arch level, it also was induced that shape effect of the large section area and yielding load obtained from deformation zone in the surrounding rock mass of tunnel have to be considered as major topics for the further development of design technique on the large section tunnel.

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Salinity Distribution and Ecological Environment of Han River Estuary (한강 하구역의 염분 분포 및 생태환경특성)

  • Park, Gyung Soo
    • Journal of Wetlands Research
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    • v.6 no.1
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    • pp.149-166
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    • 2004
  • Water quality and ecological environment in the Han River estuary was analyzed using the longterm water quality monitoring data from National Fisheries Research and Development Institute (NFRDI) and the existing data collected in this area. Based on the salinity distribution and changes of current direction in the lower Han River and its estuary, boundaries of the estuary were identified and also, distribution patterns of the phyto- and zooplankton, benthos, ichthyoplankton and fish were discussed related with the salinity changes in the macrotidal subestuary of Han River. Seasonal and spatial distribution of salinity suggested that the direct impact of freshwater be limited to the Incheon North Harbour all the year round and even extended to the southern area of Gyunggi Bay near Palmi island during limited time, usually in summer. Upper limit of salt water intrusion through the Han River is likely to be Singok underwater dam located Gimpo, Gyunggi Province, and normally limited to much lower part of the river, Jeonryuri, Gimpo. Biological boundaries of the Han River estuary exceeded the physical boundaries based on the salinity distribution. Many estuarine species in plankton and fish were found at the totally freshwater or saltwater depending on the seasons and tidal cycles. Some estuarine ichthyoplanktons showed extremely limited distributions in the estuary whereas adult fish revealed wide ranges of salinity adaptation. Critical environmental issues in the Han River estuary and its drainage basin are likely to be 1) pressure on development-promoted district for new town in the drainage area of the estuary, 2) reduction of tidal flat by reclamation, 3) pollutant input through river from municipal sewages and industrial wastes, and 4) ecological barrier between river and terrestrial systems by the military wire fence and riverside road.

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Optimal Flow Rate Evaluation for Low Energy, High Efficiency Cleaning of Forward Osmosis (FO) (정삼투 공정의 저에너지 고효율 세정을 위한 최적 유속 평가)

  • Kim, Yihyang;Kim, Jungbin;Zhan, Min;Min, Dahae;Hong, Seungkwan
    • Membrane Journal
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    • v.29 no.6
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    • pp.339-347
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    • 2019
  • Forward osmosis (FO) is operated at a lower pressure than reverse osmosis (RO), which has great advantages in terms of fouling control, maintenance, membrane cleaning, and potential energy reduction. In particular, since the membrane fouling layer of the forward osmosis process has a relatively loose and dispersed property, it is possible to control the membrane fouling by physical cleaning, unlike the reverse osmosis process. However, existing studies do not apply the proper cleaning flow rate for forward osmosis physical cleaning, and thus there is a limit that the optimal operation can not be performed. Therefore, this study aims to evaluate the justification of proper flow rate that can show high efficiency cleaning with economical energy amount. The membrane fouling experiments of the forward osmosis process were maintained at a circulating flow rate of 8.54 cm/s and the recovery rates were compared with the three cleaning flow rates. As a result of this experiment, it was confirmed that the 2 × speed cleaning showed the same efficiency as the water permeability recovery rate of the 3 × speed cleaning, and it was confirmed that the 2 × speed cleaning was an appropriate flow rate with high cleaning efficiency and economical SEC.