• Title/Summary/Keyword: Likelihood ratios

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Short Sleep Duration and Its Correlates among Cancer Survivors in Korea: the Korea National Health and Nutrition Examination Surveys

  • Yoon, Hyung-Suk;Yang, Jae Jeong;Song, Minkyo;Lee, Hwi-Won;Lee, Yunhee;Lee, Kyoung-Mu;Lee, Sang-Ah;Lee, Jong-koo;Kang, Daehee
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.11
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    • pp.4705-4710
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    • 2015
  • Background: Though a large proportion of cancer survivors are assumed to be commonly affected by sleep disturbance, few studies have focused on short sleep problems and its correlates among Korean cancer survivors. The purpose of this study was to evaluate the prevalence of short sleep in adult cancer survivors from a nationwide population-based sample and to identify risk factors for short sleep duration. Materials and Methods: Based on the fourth and fifth Korea National Health and Nutrition Examination Surveys (2007-2012), 1,045 cancer survivors and 33,929 non-cancer controls were analyzed. The prevalence of short sleep was compared between these two groups. Associations between short sleep and its correlates were evaluated using multiple logistic regression among cancer survivors: odds ratios (ORs) and 95% confidence intervals (95%CIs) were estimated after adjusting for sociodemographic factors, lifestyle factors, psychological conditions, and cancer-related factors. Results: About 8.1% of cancer survivors slept for less than 5 hours per day (6.2% men and 9.3% women), whereas this was the case for only 3.7% of non-cancer controls. Cancer survivors who had the lowest household income level showed a significantly higher likelihood for short sleep (adjusted OR 2.82, 95%CI 1.06-7.54). Self-reported poor health and depressive symptoms were found to be associated with significantly increased likelihood for short sleep in cancer survivors (adjusted OR 3.60, 95%CI 1.40-9.26 and adjusted OR 2.00, 95%CI 1.17-3.42). Gastric cancer survivors had a 3.97-fold increased risk for short sleep (95%CI 1.60-9.90). Conclusions: The prevalence of short sleep occurs at a high rate among the Korean cancer survivors, which may indicate a poorer quality of life and a higher risk of future complications in survivorship. Targeted interventions that can assist cancer survivors to cope with sleep disturbances as well as ensuring psychological stability are warranted to reduce the latent disease burden.

Reliability Based Pile Bearing Capacity Evaluation (신뢰도에 근거한 말뚝의 지지력 평가)

  • Lee, In-Mo;Jo, Guk-Hwan;Lee, Jeong-Hak
    • Geotechnical Engineering
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    • v.11 no.1
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    • pp.9-22
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    • 1995
  • The purpose of this study is to propose safety factors of pile bearing capacity based on the reliability analysis. Each prediction method involves various degrees of uncertainties. To account for these uncertainties in a systematic way, the ratios of the measured bearing capacity from pile load tests to the predicted bearing capacity are represented in the form of a probability density function. The safety factor for each design method is obtained so that the probability of pile foundation failure is less than 10-3. The Bayesian theorem is applied in a way that the distribution using static formulae is assumed to be the A-prior and the distribution using dynamic formulae or wave equation based methods is assumed to be the likelihood, and these two are combined to obtain the posterior which has the reduced uncertainty. The results of this study show that static formulae of the pile bearing capacity using the 5.p.7. N-value as well as dynamic formulae are highly unreliable and have to have the safety factor more than 7.4 : the wave equation analysis using PDA(Pile Driving Analyzer) system the most reliable with the safety factor close to 2.7. The safety factor could be reduced certain amount by adoption the Bayes methodology in pile design.

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Diagnostic Accuracy of 18F-FDG-PET in Patients with Testicular Cancer: a Meta-analysis

  • Zhao, Jing-Yi;Ma, Xue-Lei;Li, Yan-Yan;Zhang, Bing-Lan;Li, Min-Min;Ma, Xue-Lei;Liu, Lei
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3525-3531
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    • 2014
  • Objective: Fluorine-18-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) is a new technique for identifying different malignant tumors using different uptake values between tumor cells and normal tissues. Here we assessed the diagnostic accuracy of 18F-FDG-PET in patients with testicular cancer by pooling data of existing trials in a meta-analysis. Methods: PubMed/MEDLINE, Embase and Cochrane Central Trials databases were searched and studies published in English relating to the diagnostic value of FDG-PET for testicular cancer were collected. The summary receiver operating characteristic (SROC) curve was used to examine the FDG-PET accuracy. Results: A total of 16 studies which included 957 examinations in 807 patients (median age, 31.1 years) were analyzed. A meta-analysis was performed to combine the sensitivity and specificity and their 95% confidence intervals (CIs), from diagnostic odds ratio (DOR), positive likelihood ratios (PLR), negative likelihood ratio (NLR). SROC were derived to demonstrate the diagnostic accuracy of FDG-PET for testicular cancer. The pooled sensitivity and specificity were 0.75 (95% confidence interval (CI), 0.70-0.80) and 0.87 (95% CI, 0.84-0.89), respectively. The pooled DOR was 35.6 (95% CI, 12.9-98.3). The area under the curve (AUC) was 0.88. The pooled PLR and pooled NLR were 7.80 (95% CI, 3.73-16.3) and 0.31 (95% CI, 0.23-0.43), respectively. Conclusion: In patients with testicular cancer, 18F-FDG-PET demonstrated a high SROC area, and could be a potentially useful tool if combined with other imaging methods such as MRI and CT. Nevertheless, the literature focusing on the use of 18F-FDG-PET in this setting still remains limited.

Upper Bounds for the Performance of Turbo-Like Codes and Low Density Parity Check Codes

  • Chung, Kyu-Hyuk;Heo, Jun
    • Journal of Communications and Networks
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    • v.10 no.1
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    • pp.5-9
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    • 2008
  • Researchers have investigated many upper bound techniques applicable to error probabilities on the maximum likelihood (ML) decoding performance of turbo-like codes and low density parity check (LDPC) codes in recent years for a long codeword block size. This is because it is trivial for a short codeword block size. Previous research efforts, such as the simple bound technique [20] recently proposed, developed upper bounds for LDPC codes and turbo-like codes using ensemble codes or the uniformly interleaved assumption. This assumption bounds the performance averaged over all ensemble codes or all interleavers. Another previous research effort [21] obtained the upper bound of turbo-like code with a particular interleaver using a truncated union bound which requires information of the minimum Hamming distance and the number of codewords with the minimum Hamming distance. However, it gives the reliable bound only in the region of the error floor where the minimum Hamming distance is dominant, i.e., in the region of high signal-to-noise ratios. Therefore, currently an upper bound on ML decoding performance for turbo-like code with a particular interleaver and LDPC code with a particular parity check matrix cannot be calculated because of heavy complexity so that only average bounds for ensemble codes can be obtained using a uniform interleaver assumption. In this paper, we propose a new bound technique on ML decoding performance for turbo-like code with a particular interleaver and LDPC code with a particular parity check matrix using ML estimated weight distributions and we also show that the practical iterative decoding performance is approximately suboptimal in ML sense because the simulation performance of iterative decoding is worse than the proposed upper bound and no wonder, even worse than ML decoding performance. In order to show this point, we compare the simulation results with the proposed upper bound and previous bounds. The proposed bound technique is based on the simple bound with an approximate weight distribution including several exact smallest distance terms, not with the ensemble distribution or the uniform interleaver assumption. This technique also shows a tighter upper bound than any other previous bound techniques for turbo-like code with a particular interleaver and LDPC code with a particular parity check matrix.

Relationship between Resumption of Postpartum Ovarian Cyclicity and Plasma Urea Nitrogen (PUN) in Holstein Cows (젖소의 분만 후 난소 주기의 재개와 혈장 요소태 질소(PUN)와의 관계)

  • Park, S.B.;Son, J.K.;Park, S.J.;Baek, K.S.;Jeon, B.S.;Ahn, B.S.;Kim, H.S.;Park, C.K.
    • Journal of Embryo Transfer
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    • v.21 no.3
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    • pp.199-205
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    • 2006
  • The objective of this study was to investigate the resumption of postpartum ovarian cyclicity, and to determine the relationship between concentrations of plasma urea nitrogen (PUN) and resumption of ovarian cyclicity in Holstein cows. The cows were considered to have resumed ovarian cyclicity on the day of ovulation, if followed by regular ovarian cycles. 58.8 percentage of the cows (114/194) had normal resumption of ovarian cyclicity (resumption within 40days after calving), and 41.2% (80/194) had delayed resumption (resumption did not occur until> 40days after calving). Delayed resumption Type I (one or more ovarian cycles with luteal phase> 20days, i.e. prolonged luteal phase; 17.5%) and delayed resumption Type II (first ovulation did not occur until ${\ge}40days$ after calving, i.e. delayed first ovulation 22.7%) were the most common types of delayed resumption. 18 percentage of the cows (35/194) did not resume their ovarian cyclicity until 60days postpartum. Prolonged luteal phase and delayed first ovulation were two important ovarian dysfunctions that delayed postpartum resumption of cyclicity in dairy cows. Cows with PUN of <15, $15{\sim}19.9\;and\;{\ge}20mg/dl$ had the likelihood ratios of normal ovarian cyclicity of 0.9, 1.14 and 0.55, respectively. Thus, PUN concentration of $15{\sim}19.9mg/dl$ had a favorable association with postpartum resumption of cyclicity, whereas lower or higher PUN had a negative association with postpartum resumption of cyclicity.

Performance of Magnitude Sum Correlation and Vector Sum Correlation Methods for Robust Frame Synchronization Under Low Signal-to-Noise Ratios (낮은 신호 대 잡음 비에서 강건한 프레임 동기를 위한 크기 합 상관 및 벡터 합 상관 방식의 성능 평가)

  • Lee, Dong-Uk;Kim, Sang-Tae;Sung, Won-Jin
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.45 no.7
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    • pp.32-37
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    • 2008
  • Satellite communication systems including the DVB-S2 (Digital Video Broadcasting - Satellite Version 2) system require operations under low signal-to-noise ratio (SNR) and large frequency offset values, and the initial frame synchronization process necessitates a robust correlation method. While a variety of conventional correlation structures exist for the initial synchronization, each method has different characteristics and performance in different channel environments. In this paper, we propose new correlation methods which exhibit enhanced performance in low SNR and large frequency offsets, and analyze their performance. The proposed methods use the magnitude sum and vector sum of extended differential correlation values, to maximize the correlation between the received signal and the synchronization sequence by using the spanned differential correlation result. The magnitude sum correlation method has better performance compared to conventional methods including the approximated ML (Maximum likelihood) method for SNR values below 4 dB with or without frequency offsets. The vector sum correlation method has improved performance over the magnitude sum method for channels with relatively small frequency offsets.

Interpreting Mixtures Using Allele Peak Areas (Mixture에서 봉우리 면적을 활용한 유전자 증거의 해석)

  • Hong, Yu-Lim;Lee, Hyo-Jung;Lee, Jae-Won
    • The Korean Journal of Applied Statistics
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    • v.23 no.1
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    • pp.113-121
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    • 2010
  • Mixture is that DNA profiles of samples contain material from more than one contributor, especially common in rape cases. In this situation, first, the method based on enumerating a complete set of possible genotype that may have generated the mixed DNA profile have been studied for interpreting DNA mixtures. More recently, the methods utilizing peak area information to calculate likelihood ratios have been suggested. This study is concerned with the analysis and interpretation of mixed forensic stains using quantitative peak area information and the method of forensic inference for extension of material from more than or equal to three contributors. Finally, the numerical example will be outlined.

Effects of Cigarette Smoking across Three Generations and of Perceptions of the Smoking-Cancer Relationship on the Cigarette Smoking Status of Turkish University Students

  • Ozturk, Candan;Bektas, Murat;Mert, Ozlem
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.11
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    • pp.4527-4533
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    • 2014
  • Background: This descriptive and cross-sectional study aimed to investigate effects of cigarette smoking across three generations and perceptions of the smoking-cancer relationship on the cigarette smoking status of Turkish university students. Materials and Methods: The study sample comprised of 434 university students studying in different departments of a university. Data were collected using a socio-demographic data collection form and the Decisional Balance Scaleqand evaluated using the Mann-Whitney U test, CHAID and multiple regression analyses. Results: The average age of the students participating in the study is 19.6+.5.0, some 11.3% of the students reporting that they smoked cigarettes. No statistically significant relationship was ascertained between the cigarette smoking statuses of the students based on the cigarette smoking status of their grandparents (p=0.144). but there was alink to that of their parents (p=0.002). The difference between the cigarette smoking ratios of the students based on their perceptions of smoking-cancer relationship was statistically significant (p<0.001). Believing that there is a relationship between smoking and cancer decreased likelihood of cigarette smoking 3.7 fold. Cigarette smoking by grandparents, and believing that there is a relationship between smoking and cancer, and cigarette smoking by parents explained 8.3% of the cigarette smoking status of the students. Conclusions: While cigarette smoking by grandparents only indirectly influences cigarette smoking by the students, believing that there is a relationship between smoking and cancer, and cigarette smoking by parents are influential variables in determining cigarette smoking by Turkish students.

Suicide Attempts and Contributing Factors among South and North Korean-Family Youth Using the Korean Youth Risk Behavior Web-based Survey

  • Rim, Soo Jung;Lee, Min Geu;Park, Subin
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.31 no.1
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    • pp.33-40
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    • 2020
  • Objectives: There is an increasing number of North Korean adolescents in South Korea. These adolescents need clinical attention as they experience a high risk of suicidal behavior because of the childhood adversity and acculturative challenges that they face before and after arriving in South Korea. This study assessed the risk of suicide attempts among North Korean adolescents compared to South Korean adolescents, and investigated the contributing factors for each group. Methods: We used data from the Korean Youth Risk Behavior Web-Based Survey (KYRBS) spanning 2011 to 2018, in which 404 adolescents had a father and/or mother who was a North Korean native. Data on 1,212 propensity-matched South Korean adolescents were extracted from the 2011 to 2018 KYRBS. Prevalence was calculated and compared by group. Separate odds ratios were calculated by group. Results: The North Korean group had a significantly higher suicide attempt rate [unadjusted odds ratio (OR)=8.27; adjusted OR=8.45]. Multivariate analysis indicated that having a low or high socioeconomic status and depressive symptoms were significantly associated with suicide attempts in North Korean adolescents, while being female, having a high socioeconomic status, alcohol use, and depressive symptoms were significantly related to suicide attempts in South Korean adolescents. Conclusion: The results found similarities and differences in the factors associated with the likelihood of suicide attempts in the two groups. From these results, different approaches are needed when planning interventions for each group.

The Relationship between Trust as Social Capital and Participation in Cancer Screening (신뢰수준으로 측정한 사회적 자본과 암 검진 수검 간의 관계)

  • Jeong, Baek-Geun;Hwang, In-Kyoung;Sohn, Hae-Sook;Koh, Kwang-Wook;Yoon, Tae-Ho;Lim, Jeong-Hun
    • Korean Journal of Health Education and Promotion
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    • v.28 no.2
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    • pp.63-73
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    • 2011
  • Objectives: This study was conducted to investigate the relationships between trust and participation in cancer screening. Methods: Data from 2004 Busan Health Survey were analysed for the study. Multiple logistic regression was performed on participation in cancer screening by trust level with potential confounders(sex, age, education, monthly mean household income, subjective health status, smoking, alcohol intake, exercise, and daily eating habits). Results: In a total of 7,423 participants, 2,078(28.0%) were classified as cancer screening participants. High horizontal trust was associated with increased likelihood of cancer screening participation(OR(men) = 1.20, 95% CI 1.00-1.45) and (OR(women) = 1.19, 95% CI 1.02-1.39), after multiple adjustments. Respondents with high trust in health care system had significantly higher odds ratios for participation in cancer screening: 1.60(95% CI 1.27-2.02) among men and 1.18(95% CI 0.97-1.44) among women, after multiple adjustments. Conclusions: Trust was significantly associated with higher odds of cancer screening participation and could be a potent arena for increasing cancer screening participation.