• 한국융합학회논문지
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• 제12권7호
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• pp.317-327
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• 2021

본 연구는 빛 요법이 중년여성의 스트레스, 우울, 수면의 질 및 삶의 질에 미치는 효과를 비교하기 위한 무작위 대조군 연구이다. 본 연구의 대상은 I시 소재 일기관에 근무하는 중년여성 56명이며 자료수집 기간은 대조군은 2019년 8월 26일부터 9월 13일까지 실험군은 9월 16일부터 10월 4일까지 각 3주간 이루어졌다. 중년여성의 주관적 스트레스, 우울, 수면의 질 및 삶의 질은 스트레스 측정도구(NRS), 우울 측정도구(CES-D), 수면 측정도구(VHS), 삶의 질 측정도구(WHOQOL-BREF)로 측정하였으며 객관적 스트레스 지수는 Canopy9 RSA (IEMBIO, Gangwondo, Korea) 장비를 이용하여 측정하였다. 자료 분석은 IBM SPSS Statistics version 25.0을 이용하여 평균과 표준편차, 실수와 백분율, χ²-test, t-test, repeated measures ANOVA, ANCOVA로 분석하였다. 연구결과는 빛 요법을 적용한 실험군은 대조군에 비해 주관적 스트레스(F=6.30, p<.001)가 유의하게 낮았고, 삶의 질 (F=2.80, p=.049)이 유의하게 높았다. 객관적 스트레스 지수, 우울, 수면의 질에는 차이가 없는 것으로 나타났다. 결과적으로 빛 요법은 중년여성의 주관적 스트레스, 삶의 질에 부분적으로 효과를 보이고 있어 빛 노출이 제한된 직무환경에서 근무하는 중년여성을 대상으로 한 반복연구가 필요하다고 본다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2021년도 춘계학술대회
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• pp.123-125
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• 2021

임산부의 심리 상태는 태아의 건강에 많은 영향을 미친다. 따라서 건강한 태아 출산을 위해 임산부의 건강 관리는 필수이다. 많은 임산부가 겪는 임신 증상 중 하나는 감정 기복에 따른 우울감이며, 이 우울감 해소를 위한 한 가지 방법으로 조명을 이용한 라이트 테라피와 컬러테라피를 이용한 방법이다. 조명 빛의 색온도를 조절하여 색을 통해 감정에 영향을 미치도록 한다. 그 예로 자동차 판매장의 천장 조명을 태양과 비슷한 자연광과 같이 설정을 한다던가 스파숍 시설에서 편안한 분위기를 연출하기 위해 색온도가 낮은 색상을 사용한다. 본 논문에서는 실시간으로 임산부의 표정을 이미지 센서를 사용하여 심리 상태를 파악하고 조명의 색온도를 변경한다. 쉽게 구매할 수 있는 조명기기로 임산부가 받는 심리학적 영향을 이용해 산후우울증 해소하고자 연구하였다.

• The Journal of Korean Physical Therapy
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• 제34권5호
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• pp.272-277
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• 2022

Purpose: This study compared the subjective and objective sleep quality between subjects with and without thoracic hyper-kyphosis. Methods: Forty participants were divided into a hyper-kyphosis (n=17) and normal group (n=17) by thoracic spinal angle measurement. The subjective sleep quality was measured using PSQI, a self-report, and objective sleep quality was measured using an actigraphy that measures time according to sleep patterns. Results: The PSQI scores of subjects with thoracic hyper-kyphosis were significantly higher than those with normal thoracic curvature (p=0.013). The total sleep time and real sleep time were less in subjects with hyper-kyphosis than in normal subjects (p=0.006; p=0.029). The light sleep time was less in subjects with excessive spondylolisthesis than in normal subjects (p=0.010). Light sleep time was less in those with hyper-kyphosis, but deep sleep time was similar to the subjects with a normal thoracic curvature (p=0.003; p=0.140). Conclusion: Subjects with thoracic hyper-kyphosis had a decrease in subjective sleep quality, such as sleep discomfort, and objective sleep quality, such as a decrease in sleep time compared to normal subjects.

• 셀메드
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• 제13권16호
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• pp.61.1-61.3
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• 2023

Objective: Case report on improvement of pruritus through application of Ortho-Cellular Nutrition Therapy (OCNT) Method: OCNT was implemented on a Korean female patient in her 50s suffering from pruritus with unknown cause. Results: The pruritus improved upon implementation of OCNT. Conclusion: Application of OCNT can be helpful to pruritus patient.

• 셀메드
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• 제13권15호
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• pp.55.1-55.4
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• 2023

Objective: To report a case of SIBO syndrome improvement through Ortho-Cellular Nutrition Therapy. Methods: A Korean male in his 60s suffering from indigestion due to SIBO. Results: After the OCNT, symptoms of SIBO and indigestion improved. Conclusion: OCNT can be beneficial for patients with SIBO and indigestion.

• 센서학회지
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• 제15권3호
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• pp.186-191
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• 2006

In general, Cerenkov light is produced by a charged particle that passes through a medium with a velocity greater than that of visible light. Although the wavelength of Cerenkov light is very broad, the peak is in the almost visible range from 400 to 480 nm. Therefore, it always causes a problem to detect a real light signal that is generated in the scintillator on the fiber-optic sensor tip for dose measurements of high-energy electron beam. The objectives of this study are to measure, characterize and remove Cerenkov light generated in a fiber-optic radiation sensor tip to detect a real light signal from the scintillator. In this study, the intensity of Cerenkov light is measured and characterized as a function of incident angle of electron beam from a LINAC, and as a function of the energy of electron beam. As a measuring device, a photodiode-amplifier system is used, and a subtraction method using a background optical fiber is investigated to remove Cerenkov light.

• 대한의생명과학회지
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• 제15권3호
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• pp.233-239
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• 2009

The aim of this study was to evaluate the photodynamic effect of various photosensitizing agents against methicillin-resistant Staphylococcus aureus (MRSA). MRSA was exposed to light from a 632 urn diode laser (15 J/$cm^2$) in the presence of various photosensitizer, such as photofrin, photogem, radachlorine and ALA. In vivo study was performed using ICR mice. Twenty eight mice had a standard wound ($100\;mm^2$) created on the dorsum, and MRSA was inoculated into the wound region. The four groups were classified as follows: (1) the untreated control group (bacteria alone), (2) the bacteria plus light group (15 J/$cm^2$), (3) the bacteria plus photofrin group (kept in the dark), and (4) the photodynamic therapy (PDT) group (bacteria, photofrin, and light). After photofrin (dose 1 mg/kg) injection, the experimental group was irradiated with 632 urn diode laser (15 J/$cm^2$) for 30 minutes after In vitro results of PDT showed the complete killing of MRSA at the photofrin, radachlorine, and photogem However, ALA-PDT was ineffective on MRSA viability. In vivo results showed that photofrin has therapeutic effect on the wound infection. These results demonstrate that selective lethal photosensitization of MRSA can be achieved using phofrin, photogem and radachlorin. Thus, PDT can inactivate MRSA survival.

• The Journal of Korean Physical Therapy
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• 제3권1호
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• pp.229-250
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• 1991

The study was carried out to investigate and review the principles and practices of immunocytochemical method in light microscopic level. The results were as follows. 1. Immunocytochemistry is the method to search out the intracellular position of the specific meterials using antigen -antibody reaction. 2. The chief items in immunocytochemistry are antigen, antibody and chromogen. 3. The identifical fixation is cardiac perfusion fixation. 4. The tissue slides must be prepared by vibratomy. 5. All stainings are carried out with free floating staining method. 6. There are polyclonal and monoclonal antibodies used in immunocytochemistry.

• Journal of Industrial and Engineering Chemistry
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• 제67권
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• pp.429-436
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• 2018

Targeted intracellular delivery of therapeutic agents is one of the great challenges for cancer treatment. Aptamers that bind to a variety of biological targets have emerged as new targeting moieties with high specificity for targeted cancer therapy. In this study, near-infrared (NIR) light-absorbing hollow gold nanocages (AuNCs) were synthesized and conjugated with AS1411 aptamer to achieve cancer-targeted photothermal therapy. AuNC functionalized with PEG and AS1411 (AS1411-PEG-AuNC) exhibited selective cellular uptake in breast cancer cells due to selective binding of AS1411 to nucleolin, a protein that is over-expressed in cancer cells over normal cells. As a result, AS1411-PEG-AuNC showed cancer-targeted photothermal activity. This study demonstrates that aptamer-conjugated AuNCs are effective tumor-targeting photothermal agents.

• 한국광학회지
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• 제32권5호
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• pp.235-243
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• 2021

Photobiomodulation (PBM) 치료법은 특정 파장대역의 광원이 미토콘드리아에서 ATP 생성을 촉진하는 현상을 이용하는 치료법으로서 상처 치유, 염증 감소, 통증 완화 효과가 있는 것으로 알려져 생물 및 의학 분야에서 많은 관심을 받고 있다. PBM 치료법에 대한 연구는 주로 레이저, 발광다이오드(LED)를 광원으로 사용하였고, 유기발광다이오드(OLED)가 가지는 장점에도 불구하고 PBM 치료법에 사용된 사례는 제한적이다. 본 연구에서는 적색(λ = 620 nm), 녹색(λ = 525 nm), 청색(λ = 455 nm) OLED 조명모듈을 사용하여 PBM에 의한 피부관리 효과를 분석하고 LED에 의한 PBM 효과와 비교하였다. OLED 조명모듈의 PBM에 의한 피부미용효과는 적색 OLED 조명모듈에 의한 collagen type 1 합성량 증가, 녹색 OLED 조명모듈에 의한 melanin 합성 억제, 청색 OLED 조명모듈에 의한 nitric oxide 생성 억제를 각각 측정하여 입증되었다.