• BMB Reports
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• v.55 no.11
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• pp.553-558
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• 2022

Hepatocellular carcinoma (HCC) is dangerous cancer that often evades early detection because it is asymptomatic and an effective detection method is lacking. For people with chronic liver inflammation who are at high risk of developing HCC, a sensitive detection method for HCC is needed. In a meta-analysis of The Cancer Genome Atlas pan-cancer methylation database, we identified a CpG island in the USP44 promoter that is methylated specifically in HCC. We developed methylation-sensitive high-resolution melting (MS-HRM) analysis to measure the methylation levels of the USP promoter in cell-free DNA isolated from patients. Our MS-HRM assay correctly identified 40% of patients with early-stage HCC, whereas the α-fetoprotein test, which is currently used to detect HCC, correctly identified only 25% of early-stage HCC patients. These results demonstrate that USP44 MS-HRM analysis is suitable for HCC surveillance.

• International Journal of Computer Science & Network Security
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• v.23 no.3
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• pp.31-48
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• 2023

The popularization of smart devices and subsequent optimization of their sensing capacity has resulted in a novel mobile crowdsensing (MCS) pattern, which employs smart devices as sensing nodes by recruiting users to develop a sensing network for multiple-task performance. This technique has garnered much scholarly interest in terms of sensing range, cost, and integration. The MCS is prevalent in various fields, including environmental monitoring, noise monitoring, and road monitoring. A complete MCS life cycle entails task allocation, data collection, and data aggregation. Regardless, specific drawbacks remain unresolved in this study despite extensive research on this life cycle. This article mainly summarizes single-task, multi-task allocation, and space-time multi-task allocation at the task allocation stage. Meanwhile, the quality, safety, and efficiency of data collection are discussed at the data collection stage. Edge computing, which provides a novel development idea to derive data from the MCS system, is also highlighted. Furthermore, data aggregation security and quality are summarized at the data aggregation stage. The novel development of multi-modal data aggregation is also outlined following the diversity of data obtained from MCS. Overall, this article summarizes the three aspects of the MCS life cycle, analyzes the issues underlying this study, and offers developmental directions for future scholars' reference.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.10a
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• pp.207-209
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• 2022

In the IoT environment, it is possible to collect life pattern data by recognizing human physical activity from smart devices. In this paper, the proposed model consists of a prediction stage and a recommendation stage. The prediction stage predicts the scale of anxiety and depression by using logistic regression and k-nearest neighbor algorithm through machine learning on the dataset collected from life pattern data. In the recommendation step, if the symptoms of anxiety and depression are classified, the principal component analysis algorithm is applied to recommend food and light exercise that can improve them. It is expected that the proposed anxiety/depression prediction and food/exercise recommendations will have a ripple effect on improving the quality of life of individuals.

• Membrane Journal
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• v.22 no.4
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• pp.251-257
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• 2012

For the separation and recovery of n-pentane from nitrogen environment, the poly (dimethyl siloxane) (PDMS) composite membranes supported by polyetherimide (PEI) hollow fiber membranes were prepared. To characterize the gas separation properties of the resulting membranes, the permeance of n-pentane and nitrogen, concentrations of permeate and retentate, and recovery ratio were measured for n-pentane and nitrogen mixtures. The permeance of n-pentane and nitrogen, 2485.3 and 9.9 GPU, were observed respectively. As the stage cut decreases and the feed concentration increases, the n-pentane concentration in permeate tends to increase. In the meanwhile, the recovery efficiency tends to increase as the stage cut increases and the feed concentration decreases.

• Journal of Korean Academy of Nursing
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• v.27 no.3
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• pp.489-502
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• 1997

Quality of life(QOL) and fatigue in cancer patients receiving the radiotherapy was assessed. The subjects were 46 cancer patients who daily attended the radiotherapy department. Assessment was done on four occassions : the first assessment was done on the treatment simulation visit, the second one was four weeks after treatment started, the third one at the completion of treatment and the last assessment was done between six and eight week following treatment. The results are as follows : The fatigue scores of the patients at each stage of assessment ranged from 5.49 points to 7.67 points and highest score was recorded at the third assessment that is, at the completion of treatment. The fatigue points showed an increase from the 1st. to 3rd. stage. However, at the 4th. stage, fatigue points decreased to the level at the first stage of assessment. QOL were assessed in three areas namely, physical, emotional and social /functional. The QOL scores in the physical area showed the highest score, followed by social /functional and emotional areas. The QOL scores decreased gradually to the third. stage of assessment thereafter recovered to the level of the first. stage. Correlation between QOL and fatigue scores during the treatment indicated that the level of QOL decreased as the level of fatigue increased. In particular, fatigue persisted after completion of the treatment and showed a significantly negative correlation with QOL. The present study strongly suggests that a strategy to restore the emotional well being level of the patient should be devised in order to improve QOL and reduce fatigue of patients receiving radiotherapy.

• Journal of the Korean Society for Railway
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• v.10 no.5
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• pp.596-599
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• 2007

A comparative Life Cycle Assessment (LCA) among three types of Electric Motor Unit (EMU) Interior Panel (IP) was conducted. A functional unit for comparative LCA is a weight of IP for 1 EMU. It is assumed that Manufacturing stage and its upstream processes, Use stage and End of Life (EoL) stage are included in the boundary of product system. For Use stage, the weight of IP causes electricity consumption. It is assumed that aluminum IP is recycled and the other IPs are incinerated at the EoL stage. As a comparison results, aluminum IP has much larger environmental impact (5.162pt) than others (FRP IP; 4.069pt, Phenol IP; 4.053pt) even though recycling consideration is included. The manufacturing stage of aluminum IP has relative big environmental impact (1.824pt) and this point make the most important difference from other IPs (FRP IP; 0.1617pt, Phenol IP; 0.4534pt)). Despite of large weight difference between FRP IP (888.96kg) and phenol IP (316kg), the final environmental impact result has only little difference (0.016pt, 0.39%). With this result, the EMU designer can choose IP with a consideration of the environmental performance of IP.

• Korean Journal of Community Nutrition
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• v.13 no.1
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• pp.34-45
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• 2008

For the correct dietary habit and balanced dietary intake of aged people, the nutrition management that fits to the dietary behavior change stage has to be accomplished. In order to do so, in this paper, we chose 175 women that are aged more than 65 years old who are rural long life community residents and surveyed the dietary intake for 2 days including a twice depth interview and the 24 hour recall method. Also, for the sake of our aim, using the transtheoretical model, the dietary behavior change stage group was divided into the contemplation stage group, the preparation stage group, the action stage group and the maintenance stage group. The results are as follows: In the intake amount of protein (p < 0.01), vitamin $B_1$ (p < 0.05) and vitamin $B_6$ (p < 0.05), the intake amount of these nutrients in the action stage group and the maintenance stage group were significantly larger than the intake amount in the contemplation stage group and the preparation stage group. The nutrition evaluation according to the dietary behavior change stage, the ratio of subjects who took insufficient amount of energy, protein, vitamin A, and vitamin C were low as the dietary behavior change stage was upgraded. The subjects of maintenance stage group were most likely to consume vegetables more than once a day, and consume fruits and milk and milk products more than 5 times/week. MAR [13], MAR [10] and MAR [4] of subjects in the action stage group and the maintenance stage group were significantly higher than MAR [13], MAR [10] and MAR [4] of subjects in the contemplation stage group and the preparation stage group (p < 0.001). From the above results, there were differences of nutrient intakes according to the dietary behavior change stage. Therefore, it is considered that the intervention for the dietary behavior motivation induction has to be advanced before accomplishing the individually fitting intervention at the time of nutrient management intervention.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.5
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• pp.2081-2091
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• 2013

Recently, the demand on the practical application of life-cycle cost effectiveness for design and rehabilitation of civil infrastructure is rapidly growing unprecedently in civil engineering practice. Accordingly, in the 21st century, it is almost obvious that life-cycle cost together with value engineering will become a new paradigm for all engineering decision problems in practice. However, in spite of impressive progress in the researches on the LCC, the most researches have only focused on the Deterministic or Probabilistic LCC analysis approach and general bridge at design stage. Thus, the goal of this study is to develop a practical and realistic methodology for the Life-Cycle Cost LCC-effective optimum decision-making based on reliability analysis of bridges at design stage. The proposed updated methodology is based on the concept of Life Cycle Performance(LCP) which is expressed as the sum of present value of expected direct/indirect maintenance costs with expected optimal maintenance scenario. The updated LCC methodology proposed in this study is applied to the optimum design problem of an actual highway bridge with Cable Stayed Bridges. In conclusion, based on the application of the proposed methods to an actual example bridge, it is demonstrated that a updated methodology for performance-based LCC analysis proposed in this thesis, shown applicably in practice as a efficient, practical, process LCC analysis method at design stage.

• Journal of Families and Better Life
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• v.2 no.1
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• pp.111-129
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• 1984

The purpose of this study is to make a model of Family Life Cycle in Korea now. Answers to a questionnaire were collected from 724 housewives in Seoul area, 232 housewives in big cities, 203 housewives in small cities. The questionnaire contained 10 items about family situations,. Analyzing method employed for modeling to family life cycle are frequency, percentage, X2 -test . Results and findings are as follows; 1) The mean of first marriage age is 22.4yrs old. 23.5yrs old is the result of statistical materials published by E.P.B. 1975. The age of first marriage is higher according to the age, education & residential area. 2) The mean of first baby bearing age is 24.2 yrs old (generally 1 year after marriage). This age is the same as the result of statistical materials published by E.P.B. 3) the mean of last baby berating age is 32.6 yrs old compared to the E.P.B. statistical materials 3 yrs. low. This age is very different according to the age, education & residential area. 4) The mean of first child marriage age is 46.4 yrs old compared to the E.P.B. statistical materials 2.5 yrs old low. 5) the mean of last marriage age is 52.7 yrs old. this age is also 2.3 yrs low compared to the result of E.P.B. materials. 6) The number of child & interval is quite different according to the result of family planning generation of not. 7)According to the wife's employment, it does not show and difference. 8)The result of analyzing by F.L.C.,, we don't have launching stage & middle age stage apparently. So, we can make model of F.L.C. in Korea as follows (it will be change). 1) Establishment stage; from marriage to first baby born (23yrs old -24yrs old). 2) Child bearing & rearing stage; form first baby born to first child enter primary school(24 yrs old-30 yrs old). 3) Families with children's education stage; from first child primary school to high school graduation (30 yrs old-42yrs old) 4)Families with adult children stage; form first child got army college or stay at home(42 yrs- 48 yrs old). 5)Families with children's marriage stage; from first child marriage to last child marriage (48yrs old-57yrs old). 6) Aging stage; from last child marriage to self dying.

• Journal of Chest Surgery
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• v.26 no.6
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• pp.463-469
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• 1993

From May 1986 to May 1992, 72 patients were diagnosed and operated for primary lung cancer, among them 65 patients were clinically evaluated at the department of Thoracic & Cardiovascular Surgery, Masan Koryo General Hospital. 1. There were 52 males 13 females[M:F=4:1], and 5th, 6th decade of life[72%] was peak incidence. 2. The preoperative diagnosis and its positive rate were sputum cytology 35%, bronchoscopy 47%, pleural effusion cytology 80%, and pleural biopsy 50%. 3. The classification histologic types were squamous cell cancer 71%, adenocarcinoma 17%, undifferentiated cell carcinoma 4.6%, and staging classification were Stage I 31%, Stage II 22%, Stage IIIa 26%, and Stage IIIb 20%. 4. The operative methods were lobectomy 52%, pneumonectomy 36%, and open biopsy 12%, and operability was 89%, resectability was 88%. 5. The postoperative complications developed 13 patients[22%], and operative mortality was 5%. 6. The overall actuarial survival rate was 1year 70%, 2year 42%, 3year 32%, 4year 26%, and 5year 22%, according to Stage 5year survival rate was Stage I 37%, Stage II 22%, Stage IIIa 3year 12%, Stage IIIb 2year 23%. And according to operative method lobectomy 23%, pneumonectomy 19%.