• Molecules and Cells
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• v.26 no.6
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• pp.606-610
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• 2008

Phenoloxidase (PO), a melanin-forming enzyme around the foreign bodies, is an important component of the host defense system in invertebrates. Pro-PO is the enzymatically inactive zymogen form of PO. In the Drosophila genome, three Pro-PO isoforms have been identified to date. These include Pro-PO1 and 2, which are primarily expressed in crystal cells, and Pro-PO3, which is predominantly found in the lamellocytes. In this study, we demonstrated that Drosophila Pro-PO3, but not Pro-PO1 or 2, is enzymatically active in its zymogen form. These findings were evidenced by spectacular melanin forming capacities of various cells and tissues that overexpressed these pro-enzymes. Furthermore, the melanization phenotype observed in the lamellocyte-enriched $hop^{Tum-l}$ mutant was drastically reduced in the absence of PPO3, indicating that PPO3 plays a major role in the lamellocyte-mediated spontaneous melanization process. Taken together, these findings indicate that the biochemical properties, activation mode and in vivo role of Pro-PO3 are likely distinct from those of the other two Pro-PO enzymes involved in Drosophila physiology.

• Journal of the Korean Society for Precision Engineering
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• v.14 no.3
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• pp.21-27
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• 1997

This paper aims to clarify the effects of grinding conditions in form grinding of Sr-ferrite with the electro-plated diamond wheel. The main conclusions obtained were as follows. (1) The flexural strength and surface roughness of ferrite became the best at the peripheral wheel speed of 1700 m/min. (2) In the case of the depth of cut larger than 0.4mm, crack layers is induced in the ground surface, and the fracture type of chips exhibits slight ductile mode in the depth of cut smaller than 0.2mm. (3) Whe the depth of cut exceeds 0.6mm, the wheel life becomes extremely severe due to the large chipping and brack- age in the diamond grains. However, at the depth of cut .leq. 0.05mm, the diamond grain shows abrasive wear. (4) The decrease of flexural strength and the increase of surface roughness is in proportion to the increase of the feed rate. (5) Most effective nozzle setting angles with various delivery conditions of the grinding fluid, such as nozzle position .PHI. , flow rate Q, etc., were made clear.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1996.04a
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• pp.29-33
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• 1996

This paper aims to clatify the potimum grinding condition for the electroplated diamond wheel in form grinding of Sr-ferrite. The main conclusions obtained were as follows. (1) The flexural strength and surface roughness of ferrite became the highest at the peripheral wheel speed of 1700m/min. (2) In the case of depth of cut larger than 0.4mm, crack layers is induced in the ground surface, the fracture type of chips exhibits slight ductile mode in the depth of cut smaller than 0.2mm. (3) When the depth of cut exceed 0.6mm, the tool life becomes extermely short due to large chipping and brackage. However, at the depth of cut .geq. 0.05mm, the diamond grain shows abrasive wear. (4) The flexural strength and surface roughness increases in proportion to the feed rate.

• Animal Systematics, Evolution and Diversity
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• v.23 no.2
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• pp.169-173
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• 2007

Two new marine sponges in the family Chalinidae, Haliclona (Haliclona) uljinensis n. sp. and Haliclona (Reniera) hongdoensis n. sp., are collected from Uljin and Hongdo Island, Korea during 2004-2007. H. (H.) uljinensis n. sp. is closely related to H. (H.) oculata in type of spicules. However, ectosomal skeleton of H. (H.) uljinensis n. sp. is reticulated and isodictyal reticulated type but H. (H.) oculata has not any dermal specialization in skeleton. The growth form of H. (H.) uljinensis n. sp. is thin encrusting with numerous cylindrical tubes on the surface but H. (H.) oculata is solid branch form. Haliclona (R.) hongdoensis n. sp. is closely related to H. (R.) aquaeductus in skeletal structure and growth form. However, oxeas of H. (R.) hongdoensis n. sp. are larger than H. (R.) aquaeductus's.

• Animal Systematics, Evolution and Diversity
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• v.24 no.2
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• pp.205-208
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• 2008

Two new marine sponges in family Halichondriidae, Halichondria ulleungensis n. sp. and H. hongdoenesis n. sp. are collected from Ulleungdo Island and Hongdo Island, Korea by SCUBA diving during 2003-2004. H. ulleungensis n. sp. is similar to H. corrugata Diaz, Pomponi and van Soest, 1993 in the type of spicule, but it is different in growth form and choanosomal skeleton. The growth form is encrusting, with numerous erected cylindrical tube, comparing with massive-lobate of H. corrugata. The choanosomal skeleton is confused with loosely arranged oxea tract, comparing with densely tracts with many spicules of H. corrugata. H. hongdoenesis n. sp. is similar to H. surrubicunda Hoshino, 1981 in type of spicule and growth form, but this species has two kinds (thick and thin) of oxea.

• Molecules and Cells
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• v.21 no.1
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• pp.76-81
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• 2006

Tubulin is synthesized in the cell body and must be delivered to the axon to support axonal growth. However, the exact form in which these proteins, in particular tubulin, move within the axon remains contentious. According to the "polymer transport model", tubulin is transported in the form of microtubules. In an alternative hypothesis, the "short oligomer transport model", tubulin is added to existing, stationary microtubules along the axon. In this study, we measured the translocation of microtubule plus ends in soma segments, the middle of axonal shafts and the growth cone areas, by expressing GFP-EB3 in cultured Xenopus embryonic spinal neurons. We found that none of the microtubules in the three compartments were transported rapidly as would be expected from the polymer transport model. These results suggest that microtubules are stationary in most segments of the axon, thus supporting the model according to which tubulin is transported in nonpolymeric form in rapidly growing Xenopus neurons.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2019.11a
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• pp.10-11
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• 2019

The purpose of this study is to validate the environmental performance of the 'eco-friendly lightweight form' in the construction process. Unlike existing euro form and aluminum form, the proposed form does not require form oil during the process of concrete casting and is lightweight because it is made of engineering plastic. Therefore, eco-friendly lightweight form will reduce the $CO_2$ emissions in the construction process. To verify the hypothesis, the study compared existing forms and eco-friendly light weight form's $CO_2$ emissions in each stage in construction process when using 1,000 forms and 100 times from the LCI(Life Cycle Inventory) data. The total $CO_2$ emissions of the eco-friendly light weight form were 30,487kg $CO_2$, which equated to about 58% and 20% less emissions than the euroform and aluminum form. The result of the study verified that the eco-friendly lightweight form was effectively reduced $CO_2$ emission in the construction process.

• Korean Journal of Environmental Biology
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• v.34 no.2
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• pp.63-72
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• 2016

The objective of this study was to identify the life form characteristics, naturalized degree and introduction period of naturalized plants on upland fields in South Korea. The survey sites were selected in 222 upland fields over 9 provinces where are relatively dry soil conditions and are disturbed continuously by farming practices. It seemed that these uplands maintain good condition for the invasion and settlement of alien plants. Field surveys were carried out twice from May to June and from August to September in 2013. The vascular plants of the upland fields were listed into 539 taxa which contain 103 families, 320 genera, 448 species, 2 subspecies, 74 varieties and 15 forms. Ninety nine taxa were naturalized plants composed of 23 families, 64 genera, 91 species and 8 varieties. The urbanization index and naturalized index is 30.65% and 18.37%, respectively. Among total 99 naturalized plants, Compositae (30 taxa) was the most dominant family, and followed by Gramineae (14 taxa). On the basis of dormancy form, 78 taxa were belong to Th (Therophyte). In radicoid form, $R_5$ plants (86 taxa) and $R_3$ plants (14 taxa) were dominantly distributed. In disseminule form, $D_4$ including 63 taxa and $D_2$ containing 26 taxa were dominant. On the basis of growth form, erect form (e) containing 26 taxa was dominant. In conclusion, life form spectrum was $Th-R_5-D_4-e$ type. According to life form analysis, naturalized degree and introduction period, alien plants with unique characteristics may have high ability to settle and spread nationwide after inflow into South Korea. It needs further to observe some plant species with or without ecological features such as widely disseminated seeds by wind or water, high seed productivity, long life-span seeds, high germination rate of seeds, or non-dormant germinable seed.

• Journal of the Korean Society of Industry Convergence
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• v.7 no.3
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• pp.249-257
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• 2004

Forms provide meaning and deep correlation with human life All religion has symbolity through form expressions. The symbols of christanity is architectural interpreation to express the symbol of glories Form expression was Investigator from architectural design. Expression is regarded as important from the view of forms Form expressions are the motivation of expressing religion as an architectural factor. Form expression is one of proassing from architectural position Also it is the basic data of expressing glory from the architectural designer. So planning of church should be the harmony between city view and acceptance of love.

• IMMUNE NETWORK
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• v.9 no.5
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• pp.158-168
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• 2009

Tumor therapy using cytokines has been developed for last two decades. Several recombinant cytokines and tumor cell vaccines produced by cytokine gene transfer have been in clinical trials, but several side effects hamper routine clinical applications. Many cytokines are originally expressed as membrane-bound form and then processed to secretory form exerting paracrine effects. Though functional differences of these two types of cytokines are elusive yet, the membrane-bound form of cytokine may exert its effects on restricted target cells as a juxtacrine, which are in physical contacts. With the efforts to improve antitumor activities of cytokines in cancer patients, developing new strategies to alleviate life-threatening side effects became an inevitable goal of tumor immunologists. Among these, tumor cell vaccines expressing cytokines as membrane-bound form on tumor cell surface have been developed by genetic engineering techniques with the hope of selective stimulation of the target cells that are in cell-to-cell contacts. In this review, recent progress of tumor cell vaccines expressing membrane-bound form of cytokines will be discussed.