• International Journal of Advanced Culture Technology
• /
• v.11 no.4
• /
• pp.9-15
• /
• 2023

The outbreak of COVID-19 has significantly impacted various facets of individuals' lives, including perceptions, leisure activities, work-family balance, and overall life satisfaction. This study aims to explore the intricate relationships among changes in perceptions due to COVID-19, leisure activity satisfaction, work-family conflict, and life satisfaction of married working women. Employing path analysis, we examined a dataset of 1,973 married working women drawn from the 8th Korean Women and Families Panel Survey. The findings indicate that while changes in perception associated with COVID-19 did not directly affect leisure activity satisfaction and life satisfaction, they did significantly decrease work-family conflict, indirectly leading to heightened life satisfaction. Additionally, leisure activity satisfaction emerged as a mitigating factor for work-family conflict, contributing to enhanced life satisfaction. These results emphasize the importance of understanding the interplay between external factors, individual perceptions, and well-being, offering insights for devising tailored strategies. The study holds significance in guiding policies and interventions to enhance the quality of life for married working women in the context of evolving pandemic challenges.

• Journal of Christian Education in Korea
• /
• v.67
• /
• pp.229-265
• /
• 2021

The purpose of this study is to suggest educational directions by exploring the stories of changes and expectations experienced by Christian children during the COVID-19 pandemic. For this purpose, nine third- to fourth-grade elementary school children attending the church, were interviewed about their changes and expectations regarding COVID-19. The results identified five areas of experience: daily life changes, school life changes, interpersonal relationship changes, religious life changes, and emotional changes during the COVID-19 period. Daily changes included infection prevention, missing play, leisurely routine, and lethargy. Changes in school life included loss of face-to-face classes and various rule requirements. Interpersonal relationship changes included the difficulties in forming relationships with friends, teachers, parents, and siblings, and religious life changes included loss of face-to-face worship and the restoration of family worship. Various negative emotions were expressed. Analysis of the participants' expectations showed in daily life they wanted to travel and play, return to pre-corona school life, return to face-to-face worship, restore retreats, and develop fun programs as religious life expectations. Based on these children's experiences and wishes, the study suggests that educators need to recognize children's efforts during the COVID-19 period, read their hurt feelings, and develop church programs that include communication, community, and fun elements.

• Journal of Korean Academy of Nursing
• /
• v.45 no.5
• /
• pp.694-703
• /
• 2015

Purpose: This study was a prospective longitudinal study to identify changes in quality of life in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT). It was based on Roy's adaptation model. Methods: The questionnaires were administered before HSCT, 30 and 100 days after HSCT. Of the 48 potentially eligible patients, 44 (91.7%) participated in the study and 40 (90.9%) completed the questionnaires at 100 days after HSCT. Multilevel analysis was applied to analyze changes in quality of life. Results: Overall, quality of life showed a decreasing tendency from pre-HSCT to 100 days after HSCT. The adaptation level of participants was compensatory. Type of conditioning was the significant factor influencing quality of life before HSCT (${\beta}_{00}$=79.92, p <.001; ${\beta}_{01}$= - 12.64, p <.001) and the change rate of quality of life (${\beta}_{10}$= - 1.66, p =.020; ${\beta}_{11}$=2.88, p =.014). Symptom severity (${\beta}_{20}$= - 1.81, p =.004), depression (${\beta}_{30}$= - 0.58, p =.001), social dependency (${\beta}_{40}$= - 0.35, p =.165), and loneliness (${\beta}_{50}$= - 0.23, p =.065) had a negative effect on changes in quality of life. Symptom severity and depression were statistically significant factors influencing changes in quality of life. Conclusion: According to the results of this study, the development of nursing intervention is needed to improve quality of life in patients undergoing allogeneic hematopoietic stem cell transplantation in the early immune reconstruction period. The interventions should include programs to enhance coping capacity and programs to help control symptom severity and depression. Also these interventions need to be started from the beginning of HSCT and a multidisciplinary approach would be helpful.

• Journal of muscle and joint health
• /
• v.30 no.2
• /
• pp.83-92
• /
• 2023

Purpose: This study aims to compare and analyze the changes in the physical and mental health status of middle-aged women before and after menopause and their quality of life over the past 10 years. Methods: A descriptive study was conducted by using secondary data from the 4th and 7th Korea National Health and Nutrition Examination Survey (KNHANES) involving middle-aged women in menopause (N=8,363). Data were analyzed using the complex sample x² test. Results: Compared to 10 years ago, notable changes were observed in general characteristics. These included increase in age, education level, economic activity, and urban residency. In addition, there was an increase in alcohol consumption, a decrease in smoking, and a decline in regular exercise. The study also observed changes in obesity rates and an increase in dyslipidemia and stress levels, along with positive changes across all aspects of quality of life. Conclusion: The results indicate temporal changes in general characteristics, major physical and mental health factors, and the quality of life of middle-aged women in menopause. Thus, it is essential to consider these changes when designing health interventions such as health promotions and education initiatives for middle-aged women experiencing menopause. Further research is necessary for identifying factors influencing the quality of life of middle-aged women in menopause.

• Journal of Korea Entertainment Industry Association
• /
• v.14 no.7
• /
• pp.501-509
• /
• 2020

The purpose of this study was to provide basic information about the analysis of the changes in problem behavior, sleep quality and quality of life of the people with intellectual disability through the application of the heavy work activities. This study subjects were 10 people with intellectual disability and they participated in the this activities for 12 weeks. Through the application of heavy work activities, Korean-Adaptive Behavior Scale was used to analyze the changes in problem behavior, sleep quality assessment was used to analyze the changes in sleep quality and satisfaction with life scale was used to analyze the changes in quality of life. As the results, the decrease of problem behavior, the improvement of sleep quality and quality of life were showed. Heavy work activities should be act to decrease the problem behavior, improve sleep quality and quality of life of the study subjects. Thus, heavy work activities should be considered to apply for the people with intellectual disability.

• BMB Reports
• /
• v.51 no.12
• /
• pp.623-629
• /
• 2018

For mechanical force to induce changes in cellular behaviors, two main processes are inevitable; perception of the force and response to it. Perception of mechanical force by cells, or mechanosensing, requires mechanical force-induced conformational changes in mechanosensors. For this, at least one end of the mechanosensors should be anchored to relatively fixed structures, such as extracellular matrices or the cytoskeletons, while the other end should be pulled along the direction of the mechanical force. Alternatively, mechanosensors may be positioned in lipid bilayers, so that conformational changes in the embedded sensors can be induced by mechanical force-driven tension in the lipid bilayer. Responses to mechanical force by cells, or mechanotransduction, require translation of such mechanical force-induced conformational changes into biochemical signaling. For this, protein-protein interactions or enzymatic activities of mechanosensors should be modulated in response to force-induced structural changes. In the last decade, several molecules that met the required criteria of mechanosensors have been identified and proven to directly sense mechanical force. The present review introduces examples of such mechanosensors and summarizes their mechanisms of action.

• Asian Oncology Nursing
• /
• v.11 no.3
• /
• pp.229-236
• /
• 2011

Purpose: The purpose of this study was to examine the sensation changes in upper extremity and the quality of life for post-operative mastectomy patients. Methods: This study used a descriptive study design. The participants were 132 women who had mastectomies after being diagnosed with breast cancer and were participating in breast cancer self-help groups. The sensation changes in the arm of the surgery site was measured by the arm symptoms which were subjective uncomfortable feelings of the affected arm, and the quality of life was measured by Medical Outcomes Study Short Form-36. Collected data were analyzed by ANOVA, t-test, ${\chi}^2$-test and multiple regression with SPSS WIN 12.0 program. Results: Patients with stage IV breast cancer had severe changes in sensation of the arm. Participants with lymphedema had statistically significant changes in sensation compared to participants without lymphedema, but the quality of life was not different between the two groups. Pain by the SF 36 was statistically different between the two groups, with- and without-lymphedema. The factors in upper extremity's sensation changes which influence on quality of life were pain and heaviness. Conclusion: Nursing intervention for relieving pain and heaviness of the affected arm needs to be developed in order to improve QOL of the breast cancer survivors.

• Journal of fish pathology
• /
• v.33 no.1
• /
• pp.23-34
• /
• 2020

In recent years, global warming is causing dramatic environmental changes and deterioration, such as hypoxia, leading to reduced survival rate and growth performance of farmed aquatic animals. Hence, understanding systemic immuno-physiological changes in fish under environmental stress might be important to maximize aquaculture production. In this study, we investigated physiological changes in rainbow trout exposed to hypoxic stress by monitoring changes in blood chemistry, leukocyte population, and expression levels of related cytokine genes. Hematological and serological factors were evaluated in blood obtained from rainbow trout sampled at a dissolved level of 4.6 mg O₂ L^-1 and 2.1 mg O₂ L^-1. Blood and head kidney tissue obtained at each sampling time point were used to determine erythrocyte size, leukocyte population, and cytokine gene expression. The level of LDH and GPT in fish under progressive hypoxia were significantly increased in plasma. Likewise, the (Granulocyte + Macrophage)/lymphocyte ratio (%) of fish exposed to hypoxia was significantly lower than that in fish in the control group. Such changes might be due to the rapid movement of lymphocytes in fish exposed to acute hypoxia. In this study, significant up-regulation in expression levels of IL-1β and IL-6 gene appeared to be involved in the redistribution of leukocytes in rainbow trout. This is the first study to demonstrate the involvement of cytokines in leukocyte trafficking in fish exposed to hypoxia. It will help us understand systemic physiological changes and mechanisms involved in teleost under hypoxic stress.

• BMB Reports
• /
• v.56 no.9
• /
• pp.469-481
• /
• 2023

The gut microbiome is widely recognized as a dynamic organ with a profound influence on human physiology and pathology. Extensive epidemiological and longitudinal cohort studies have provided compelling evidence that disruptions in the early-life microbiome can have long-lasting health implications. Various factors before, during, and after birth contribute to shaping the composition and function of the neonatal and infant microbiome. While these alterations can be partially restored over time, metabolic phenotypes may persist, necessitating research to identify the critical period for early intervention to achieve phenotypic recovery beyond microbiome composition. In this review, we provide current understanding of changes in the gut microbiota throughout life and the various factors affecting these changes. Specifically, we highlight the profound impact of early-life gut microbiota disruption on the development of diseases later in life and discuss perspectives on efforts to recover from such disruptions.

• Journal of Korean Society for Quality Management
• /
• v.23 no.3
• /
• pp.93-101
• /
• 1995

We present a brief survey concerning the relations between mean residual life and failure rate. Change points of mean residual life and failure rate are known to be different in general and we explore such situations in this paper. A few parametric models which show bathtub-shaped failure rate are examined in details, including the shape of its corresponding mean residual life function. We give some graphical comparisons of trend changes of mean residual life and failure rate for various choices of parameters for each parametric model.