• The Journal of Internal Korean Medicine
• /
• v.28 no.2
• /
• pp.321-332
• /
• 2007

Objectives : Anticancer and immune-modulating effects of several Korean medical prescriptions including Yukgunja-tang, Bohwa-tang, Sogam-Won, and Kamiboa-tang were investigated. Methods : In vitro anti-cancer effects were measured by cytotoxicity MTT assay using SNU-1 gastric cancer cell lines, In vivo anti-cancer effects were measured by increased life span of S-180 sarcoma-injected ICR mouse. Immune-modulating effects were analyzed by measuring hemagglutinin titer, appearance of rosette forming cells, lymphocyte proliferation, and phagocytic index in methotrexate-pretreated mice. Results : In vitro assay showed that only Sogam-won showed cytotoxic effect with $IC_{50}$ of 87.9 ${\mu}g/ml$. All other prescriptions showed no cytotoxic effects against SNU-1 gastric cancer cell line. However, in vivo assay showed that Sogam-won showed lowest anti-cancer effects in contrast to its highest cytotoxic effects, Kamiboa-tang, which showed no cytotoxic effect, showed the highest in vivo anticancer effects, with increased life span of 140%. Kamiboa-tang showed significant immune-enhancing activities by significantly increasing rosette forming cells, lymphocyte proliferation, and phagocytic index in methotrexate-pretreated mice (P<0.05). Conclusion : The anticancer effect of Kamiboa-tang is not mediated by direct inhibition of cancer cells but is mediated by improving immune reactions against cancer cells.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.17 no.2
• /
• pp.560-567
• /
• 2003

Antimetastatic effects of Agaricus mixed prescription (AMP) were studied in the respect of blood-borne metastasis. For this aim, cytotoxicity against various cancer cells and normal cells, Chicken Chorioallantoic membrane (CAM) assay, cancer cell adhesion assay, platelet aggregation assay, pulmonary colonization, life span of S-180 implanted mice, and cytokine release assay were evaluated, respectively. The results were summarized as follows; AMP did not exert any cytotoxicity against all cell lines with IC50 of 25mg/ml on B16BL6. AMP disrupted formation of CAM at 1mg/ml. AMP was suppressive in adhesion assay of B16BL6. AMP also inhibited tumor induced platelet aggregation. In pulmonary colonization assay by B16BL6, the number of colonies in the lungs was significantly decreased in sample group than in control group. In animal study with S-180, the life span of AMP treated group was extended than that of control group. IL-12 was effectively increased in AMP treated group in cytokine release assay. Taken together, AMP can be possibly applied to cancer or metastasis.

• Smart Structures and Systems
• /
• v.15 no.3
• /
• pp.555-576
• /
• 2015

The large number of long-span bridges constructed in China motivates the applications of structural health monitoring (SHM) technology. Many bridges have been equipped with sophisticated SHM systems in the mainland of China and in Hong Kong of China. Recently, SHM technology has been extended to field test systems. In this view, SHM can serve as a tool to develop the methods of life-cycle performance design, evaluation, maintenance and management of bridges; to develop new structural analysis methods through validation and feedback from SHM results; and to understand the behavior of bridges under natural and man-made disasters, rapidly assess the damage and loss of structures over large regions after disasters, e.g., earthquake, typhoon, flood, etc. It is hoped that combining analytical methods, numerical simulation, small-scale tests and accelerated durability tests with SHM could become the main engine driving the development of bridge engineering. This paper demonstrates the above viewpoint.

• Earthquakes and Structures
• /
• v.8 no.3
• /
• pp.681-697
• /
• 2015

Iran as one of the countries located on the Alpine-Himalayan seismic belt has recently experienced a few number of catastrophic earthquakes. A well-known index of how buildings are affected by earthquakes is through assessment of probable Peak Ground Acceleration (PGA) and structures' response spectra. In this research, active faults around Kerman and Birjand, two major cities in eastern parts of Iran, have been considered. Seismic catalogues are gathered to categorize effects of surrounding faults on seismicity of the region. These catalogues were further refined with respect to time and space based on Knopoff-Gardner algorithm in order to increase statistical independency of events. Probabilistic Seismic Hazard Analysis (PSHA) has been estimated for each of cities regarding 50, 100, 200 and 500 years of structures' effective life-span. These results subsequently have been compared with Deterministic Seismic Hazard Analysis (DSHA). It has been observed that DSHA not necessarily suggests upper bound of PSHA results. Furthermore, based on spectral Ground Motion Prediction Equations (GMPEs), Uniform Hazard Spectra (UHS) and spectral acceleration were provided for 2% and 10% levels of probability of exceedance. The results show that increasing source-to-site distance leads to spectral acceleration reduction regarding each fault. In addition, the spectral acceleration rate of variation would increase if the source-to-site distance decreases.

• Journal of Veterinary Clinics
• /
• v.10 no.1
• /
• pp.101-109
• /
• 1993

This study was attempted to develop a rearing method of the tick(Haemaphysalis longicornis) at the laboratory in winter. The rearing conditions for ticks in winter were summarized as follows; Even in the winter, under controlled Incubator on 25~3$0^{\circ}C$ and 90~95%, temperature and humidity, respectively, it is possible to rear the ticks normally as on summer. in the usual laboratory room temperature and humidity, 20~$25^{\circ}C$ and 51 ~77%. In the ticks collected in summer, the life span of the ticks, from hatching to death, was 91～129(112.8$\pm$15.2) days in the lagoratory, and the number of the oviposited eggs from a tick were about 1,680~2,460 and the hatching rate of the oviposited eggs was about 95(92~98)%. The life span of the ticks which were reared in the laboratory in winter was 89-138(112.2$\pm$21.1) days, and the number of the oviposited eggs from the tick were about 1,382~2,674 and the hatching rate of them was about 89.5(87~92)%. In the rearing of the tick at the laboratory, the dogs, rabbits and mice were able to use the hosts for the tick. The proper temperature to feed the ticks on the cattle in the cold season was obtained by $Hokalong^{\circledR}$ which were attached on the out side of sac which covered bovine ear where attached ticks.

• Research in Community and Public Health Nursing
• /
• v.9 no.1
• /
• pp.40-63
• /
• 1998

A long life is the desire of many people. The purpose of this study was to describe long life factors for people aged one hundred and above on Chju island. The research was conducted using a phenomenological method to add understanding to this subject. The field work for this study was done from July, 1997 to February, 1998 on Cheju island. The sample consisted of 10 persons of one hundred or above and 12 families. They were audio-recorded and analyzed using Colaizzi's (1978) method. The results of the present study shows the following: The thoughts of the persons one hundred and above showed ten important concepts; 'dietary regimen', 'mental regimen', 'sleep regimen', 'residence regimen', 'health regimen', 'labor regimen', 'exercise regimen', 'being born', 'filial piety and posterity', 'attachment to life'. Concerning 'Dietary Regimen': Dietary regulation, Preferential food intake, Living on vegetables, Light eating, and concern for longevity in food intake were important. Concerning 'Mental Regimen' : Harmony, Clearheadedness, Mildness, Abstinence, Generosity, Relaxation, Gaiety, Inspiration and Strength were important. Concerning 'Sleep Regimen'; Enough sleeping hours, Sound sleep, Curved sleeping posture, and Comfortable bedding were important. Concerning 'Residence Regimen' ; Clean dwelling, Pleasant surroundings, Thatched house life, Living in the village with good-hearted people, and Regular life were important. Concerning 'Health Regimen'; Temperance of drug, use Proper temperature, Proper humidity, and a Clean body were important. Concerning 'Labor Regimen'; Agricultural labor, Diligence, and Domestic labor were important. Concerning Exercise Regimen': Proper exercise, and Sunbathing were important. Concerning 'Being Born' ; Strong physical constitution, Longevity lineage, and Destiny were important. Concerning 'Filial Piety and Posterity' : Showing respect to a long-lived elder and Reducing anxiety were important. Concerning 'Attachment to Life' ; The desire to live long was important. The following conclusion was made from the above results. Human beings cannot avoid death, but the span of life can be prolonged to the maximum span of human life by wisdom, health care, and proper environmental conditions. As a result, a health regimen must be imposed for longevity such as controling food intake, having positive thoughts, being relaxed, sleeping enough, clean dwelling, taking care of oneself which can improve immunity and resistance to decrease, as well as proper labor and exercise. In addition, when filial piety is served, the desire of longevity and retaining one's youthfulness for a long time can be achieved. These should be done to live long and lead a qualitative life. By the results of this research, the following is suggesed for nursing. To satisfy the basic nursing principle that nursing must be practiced to help people live long, education must be spread to people who are nursed and their family so that they can lead a healthy life. And in nursing elders, nurses must recognize that elders have a strong desire for life, even though they may have negative thoughts about life at times. Therefore nurses have to respect the elders' value of life, and help them improve their self-esteem and self -fulfilment.

• Journal of Families and Better Life
• /
• v.10 no.2
• /
• pp.209-229
• /
• 1992

The purpose of this study is to develop Family Life Education program for Marital education in Korea. In order to realize the about research purpose, this study is divided into three sections. First, nature conception and contents f Family Life Education, second, patterns and models for Family Life Education Program in USA and Korea, and Third, the future of Family Life Education. Family Life Education (FLE) is an education originated in reaction to changing social conditions, industrialization and urbanization, it deals with the perceived inadequacies of families to cope with these changes, thereby reduction social problems involved with, and improving family life. With and assumption that the studies about FLE have not been so active in Korea, the present thesis examines the FLE in Korea. The necessity of marital education in Korea Is based upon the theories of FLE in the United States of America. Also, it atempts to formulate a tentative plan for the promotion of a FLE program in Korea. The concept of FLE in Korea was manifested in the social educational law and life-span education. specified as 4th among ten presidential regulations. It is defined as " the Life-span developmental education to enhance the quality of human life, to solve family problems, to develop an individual's potentiality and to strengthen the family relations. of the FLE programs, the marital education is considered one of the furcial wubjects becaused it is the core of the family life. With this premise, FLE tries to wupport the healthy mrital relations. subsequently helping to explore the family potentiality and to strengthen family ties. The objects of the FLE program are unmarried, pre-marred , and married persons. For the married persons, the FLE program should be arranged in accordance with their rrital status divided by the family life cycle so that they may prevent possible family problems at each stage of the family life. Also, to prevent the problems occurred in the course of carrying out family functions, the FLE program should be provided with on the basis of a family unit, thereby improving the quality of the family functions. The FLE is to hep persons begin smoothly the adaption process for a successful marital relations. For the FLE to be practised more widely systematically, research on family education--that is basic study, research and production and evaluation or the FLE to be carried out by research institute wholly responsible for it-- should be done first.

• Journal of Korea Technical Association of The Pulp and Paper Industry
• /
• v.45 no.1
• /
• pp.67-74
• /
• 2013

Organosolv ethanolamine pulping for oil palm empty fruit bunches(EFB) were evaluated in this study. The screen yield by the ethanolamine pulping were higher than that by the soda pulping at the same operation conditions. The higher concentration of ethanolamine solvent resulted in the higher yield and the lower contents of residual lignin. The EFB pulp fibers were the narrower in fiber width but the higher in coarseness than those of the hardwood pulp fiber, while the fiber length of the EFB pulp fiber were similar to that of the hardwood fiber. The intrinsic zero span tensile testing showed the EFB pulp fiber by the 80% ethanolamine pulping were the stronger than the fiber by the soda pulping. The results of this study supported that the ethanolamine pulping could be used as an alternative pulping method for the EFB.

• Journal of the Korean Society of Industry Convergence
• /
• v.7 no.2
• /
• pp.161-166
• /
• 2004

The impact factor of bridges is analyzed based on experimental data to examine the characteristics of the dynamic responses of bridges. The experimental impact factors are compared with the impact factor of Korean Highway Design Specification and Japan T-load in terms of the span length. According to the superstructural types of bridges, the variation of the impact factor is analyzed. When vehicles are passing on a bridge, the dynamic effect acts on the bridge impact factor more than at the time of design because of the velocity of vehicles, the surface roughness reduction due to the deterioration of the bridge deck pavement, and the disconnection of the bridge entrance and the expansion joint. Because the actual value is greater than the expected value at the time of design, the dynamic response of the bridge accelerates the deterioration of the bridge due to the accumulation of fatigue, and the bridge's life-time is shortened and can have an influence on the serviceability and safety of the bridge.

• Journal of Families and Better Life
• /
• v.28 no.6
• /
• pp.47-57
• /
• 2010

This study examines the effects of parental variable(parental support and supervision), temperament(activity level, attention span/persistence, and emotionality) and the internal locus of control on self-regulation of children. Data were collected from 455 5th and 6th graders and analyzed with Pearson's correlations and pathway analysis. The results were as follows : Children's temperament, internal locus of control and parental variable directly affected children's self-regulation. Parental variables mediated between children's temperament and internal locus of control and self-regulation. Internal locus of control mediated between children's temperament and self-regulation: in addition, the most important variable predicting children's self-regulation was children's attention span/persistence temperament.