• The Journal of Internal Korean Medicine
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• v.39 no.6
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• pp.1206-1224
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• 2018

Purpose: This systematic review was planned and performed in order to determine the clinical effectiveness of acupuncture for non-alcoholic fatty liver disease (NAFLD). Methods: We searched related randomized controlled trials in several medical online databases, including China National Knowledge Infrastructure (CNKI), Excerpta Medica dataBASE (EMBASE), Public/Publisher MEDLINE (PubMed), Cochrane Central Register of Controlled Trials (CENTRAL), National Digital Science Library (NDSL), and Research Information Sharing Service (RISS). NAFLD related outcomes were extracted from the included trials and meta-analyzed. Results: From the 8 included trials, the values of the following examinations were extracted: liver ultrasonography, liver CT, body fat CT, aspartate transaminase (AST), alanine transaminase (ALT), gamma-glutamyltransferase (GGT), total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) cholesterol, high density lipoprotein (HDL) cholesterol, fasting blood sugar (FBS), hosmeostatic model assessment for insulin resistance (HOMA-IR), weight, body mass index (BMI), waist hip ratio (WHR), obesity degree, body fat mass, body fat rate, leptin, malondialdehyde (MDA), and super oxide dismutase (SOD). In the 4 outcomes, cure rate in liver ultrasonography (RR=1.56; 95%CI=1.05~2.31; P=0.03), cure rate in liver CT (RR=2.23; 95%CI=1.33~3.72; P=0.002), TC (MD=-0.78; 95%CI=-1.41~-0.15; P=0.02), and TG (MD=-2.05; 95%CI=-3.88~-0.21; P=0.03), acupuncture was more effective than the control intervention. Conclusions: In this meta-analysis, acupuncture relieved hepatic steatosis, and reduced TC, and TG in NAFLD patients. more well-planned studies are still needed due to the heterogeneity and the considerable methodological flaws in the analyzed trials.

• Journal of Korean Medicine Rehabilitation
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• v.33 no.3
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• pp.67-78
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• 2023

Objectives To evaluate the evidence supporting the efficacy and safety of electroacupuncture for lumbar spinal stenosis. Methods We searched eight electronic databases (PubMed, EMBASE, Cochrane Library, Chinese Academic Journals, Research Information Sharing Service, ScienceOn, KMBASE, DBpia) and related two journals up to March 2023. We included randomized controlled trials of testing electroacupuncture for lumbar spinal stenosis patients. The methodological quality of relevant randomized controlled trials assessed by the Cochrane risk of bias tool. Results Among 90 articles that were searched, seven randomized controlled trials involving 474 participants were finally selected in this systematic review. Electroacupuncture was more effective on lumbar spinal stenosis compared with other treatments including analgesics, acupuncture, bed rest and exercise therapy, but showed ambiguous effect compared with physical therapy. Most of the side effects and adverse reactions were reported as minor and temporary. Conclusions Electroacupuncture for lumbar spinal stenosis was more effective than analgesics, acupuncture, bed rest and exercise therapy. In terms of safety, it was limited because there are many papers that do not mention side effects and adverse reactions related to electroacupuncture. Additional studies are needed to determine the effect of electroacupuncture on lumbar spinal stenosis.

• Biomedical Science Letters
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• v.13 no.4
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• pp.263-272
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• 2007

Nebulin is a giant actin binding protein (600-900 kDa) which is specific to skeletal muscle. This protein is known to regulate thin filaments length in sarcomere as a molecular template. The C-terminus of nebulin is located in the Z-disc of muscle sarcomere and is bound to other proteins such like myopalladin, titin, archvillin, and desmin. The N-terminus of nebulin binds to tropomodulin at the pointed ends of the thin filaments. In recent research, nebulin not only found in brain but also expressed in heart, stomach, and liver. So, the roles of nebulin in non-muscle tissue have been studied. However, lack of information or studies on nebulin binding proteins and nebulin function in brain are available so far. Therefore, the current study have investigated a novel binding partner of Nebulin C-terminus by using yeast two-hybrid screening with human brain cDNA library. Nebulin C-terminus, containing simple repeats, serine rich and SH3 domain, interacts with osteonectin C-terminal region. The specific interaction of nebulin and osteonectin were confirmed in vitro by using GST pull-down assay and reconfirmed in vivo by using transfected COS-7 cells with EGFP-tagged nebulin and DsRed-tagged osteonectin. Consequently, this study identified SH3 domain in nebulin C-terminus specifically binds to extracellular Ca-binding (EeC domain in osteonectin. Also, nebulin C-terminus fusion protein colocalized with osteonectin EC domain fusion protein in transfected COS-7 cells. The current study found the interaction between nebulin and osteonectin in human brain for the first time and suggested the nebulin in brain may be associated with osteonectin, as a regulator of cell cycle progression and mitosis.

• The Journal of Korean Obstetrics and Gynecology
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• v.34 no.4
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• pp.46-61
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• 2021

Objectives: The purpose of this review is to overview the studies of traditional herbal medicine for chronic pelvic inflammatory disease. Methods: We searched relevant studies using seven databases (The Journal of Korean obstetrics & gynecology, National Digital Science Library (NDSL), Research Information Sharing Service (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS), Pubmed, Cochrane, Chinese National Knowledge Infrastructure (CNKI)). Data retrieval was carried out on April 5, 2021 and the papers published from January 1, 2015 to March 31, 2021 were included. The risk of bias was assessed by using Cochrane's risk of bias tool. Results: 524 studies were searched in domestic and foreign databases, and 7 studies were finally selected. In all studies, the treatment group was treated with oral traditional herbal medicine and the control group was treated with western medicine. Although the evaluation index was slightly different for each study, all studies used total efficacy rate index. In all 7 studies, the treatment group was more effective than the control group. Conclusions: Traditional herbal medicine can be an effective option in treating chronic pelvic inflammatory disease. Further high quality studies which include large number should be carried out to confirm the evidence and safety of traditional herbal medicine treatment.

• Journal of the Korea Convergence Society
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• v.9 no.9
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• pp.9-14
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• 2018

This study aims to investigate an importance of Author keyword with analysis the position of author keyword. An analysis was carried out on the position of author keyword. we examined an importance of Author keyword by using degree centrality, closeness centrality, betweenness centrality, eigenvector centrality. In the next stage, we performed analysis on correlation between network centrality measures and the position of keyword. As a result, degree centrality, closeness centrality, betweenness centrality, eigenvector centrality both has a high value in 4th author keyword order. eigenvector centrality was the comparatively effective method to separate of author keyword order method than other 3 centrality. Correlation analysis result shows that the network analysis value are increasing in order. This study has significance in that it was able to examine the author keyword behavior. Future research is needed to identify and supplement future situational factors, behavior, and psychology.

• Journal of Korean Medicine Rehabilitation
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• v.34 no.2
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• pp.29-49
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• 2024

Objectives The purpose of this study is to systemically review the recent studies in the Korean medicine treatments for torticollis. Methods We search the clinical studies from January 1, 2018 to December 31, 2023. The studies were searched through 10 databases (Oriental Medicine Advanced Searching Integrated System, Korean studies Information Service System, Research Information Sharing Service, Korean Medical Database, ScienceON, PubMed, Cochrane Library, Embase, Wanfang Data, China National Knowledge Infrastructure). Results A total of 19 studies were included in the study. 12 studies were case report studies, 5 studies were randomized controlled trials, 2 studies were non-randomized controlled trials. Of the 19 interventions, Chuna was the most used in this study and of the 28 evaluation tools, Sternocleidomastoid thickness was the most used in this study except efficiency rate. All 19 studies had improvements after treatment, and 8 studies had statistically significant improvements. As a result of the study, we found that Chuna, GB, GB20, BL10, Glycyrrhiza uralensis were commonly used Korean medicine treatments for torticollis. Conclusions We analyzed the Korean medicine treatments for torticollis. Through this study, we found that the Korean medicine was effective for torticollis. However, more research is needed to confirm the more detailed effect.

• Journal of Korean Physical Therapy Science
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• v.18 no.4
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• pp.31-46
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• 2011

The purpose of this survey was to give data and information about type and needs of Home Physical Therapy, Visiting Physical Therapy and School Physical Therapy for physical and nurse. The subjects were 154(99 physical therapists and 55 nurses) who were working at geriatric rehabilitation hospitals and children hospitals. The period of questionary collection was from the 15 of August to the 15th of September 2011. And data was analysis from 99 articles such as journals related to physical therapy, and searched with keyword 'home and visiting physical therapy' by web site and Korea National Assembly Library from 1991 to 2011. The data was analysis with percentage, mean, standard deviation and ANOVA by SPSS PC 12.0. The results were as follows; 1. The definition of 'Home Physical Therapy' has been community based on physical therapy service for the patient who had diagnosis by medical doctor, has been based on medical law. The definition of 'Visiting Physical Therapy' has been community based on physical therapy service at home for the patient who had diagnosis by medical doctor, for the national basic living security, and senior citizen over 65 years who lives alone, has been based on law for community health and law of long term health insurance. The definition of 'School Physical Therapy' has been school based on physical therapy service at school after class for the disabled children who are studying at school, has been based on special education law article 28. 2. As for the knowledge of the Home and Visiting and School Physical Therapy, both groups PT and nurse were 'I do not know'125(81.3%) of the difference the concept of 3 definitions, so it means to need education and information about the different concept of three physical therapy. As for the needs of home and visiting physical therapy, both groups of PT and Nurse were 'needs' 151(98.1%). Physical therapist showed of 'Needs' on visiting physical therapy 35(35.4%), home physical therapy 32(32.3%), and schole physical therapy 32(32.3%). Nurse showed of 'Needs' on home physical therapy 23(41.8%). visiting physical therapy 19(34.5%), school physical therapy 13(23.6%). Therefore it is necessary to have home and visiting physical therapy as for the elderly and disabled person. 3. As for the qualification of Home and Visiting physical therapist, both PT and nurse groups showed as follows; take post graduation education program for home and visiting therapy after became PT : home physical therapist 108(70.1%), visiting physical therapist 106(68.8%). So it means education center or university can be developed post graduation program for home and visiting physical therapist. 4. As for the 'Needs' of school physical therapy, both groups of PT and nurse showed as follows; 'Needs' 142(92.2%), 'Needs superviser education program' 148(96.1%), in PT group showed 'I will participate of education program' 92(92.9%). 5. As for the present states of research papers or report of home, visiting, and school physical therapy was as follows; the 103 papers for 8 fields about' the needs of home and visiting physical therapy' from 1991 to 2011, the 13 papers for 2 fields about school physical therapy from 2001 to 2011, so total papers were 114 articles.

• Journal of Korea Water Resources Association
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• v.55 no.4
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• pp.301-308
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• 2022

Algae is an indispensable primary producer in the ecosystem by supplying energy to consumers in the aquatic ecosystem, and is largely divided into green algae, blue-green algae, and diatoms. In the case of blue-green algae, the water temperature rises, which occurs in the summer and overgrows, which is the main cause of the algae bloom. Recently, the change in the occurrence time and frequency of the algae bloom is increasing due to climate change. Existing algae survey methods are performed by collecting water and measuring through sensors, and time, cost and manpower are limited. In order to overcome the limitations of these existing monitoring methods, research has been conducted to perform remote monitoring using spectroscopic devices such as multispectral and hyperspectral using satellite image, UAV, etc. In this study, we tried to confirm the possibility of species classification of remote monitoring through laboratory-scale experiments through algal culture and river water collection. In order to acquire hyperspectral images, a hyperspectral sensor capable of analyzing at 400-1000 nm was used. In order to extract the spectral characteristics of the collected river water for classification of algae species, filtration was performed using a GF/C filter to prepare a sample and images were collected. Radiation correction and base removal of the collected images were performed, and spectral information for each sample was extracted and analyzed through the process of extracting spectral information of algae to identify and compare and analyze the spectral characteristics of algae, and remote sensing based on hyperspectral images in rivers and lakes. We tried to review the applicability of monitoring.

• Korean Journal of Remote Sensing
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• v.33 no.2
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• pp.189-199
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• 2017

Thisstudy quantitatively analyzed the research trendsin the use ofICT ofthe environmental field using the text mining technique. To that end, the study collected 359 papers published in the past two decades(1996-2015)from the National Digital Science Library (NDSL) using 38 environment-related keywords and 16 ICT-related keywords. It processed the natural languages of the environment and ICT fields in the papers and reorganized the classification system into the unit of corpus. It conducted the text mining analysis techniques of frequency analysis, keyword analysis and the association rule analysis of keywords, based on the above-mentioned keywords of the classification system. As a result, the frequency of the keywords of 'general environment' and 'climate' accounted for 77 % of the total proportion and the keywords of 'public convergence service' and 'industrial convergence service' in the ICT field took up approximately 30 % of the total proportion. According to the time series analysis, the researches using ICT in the environmental field rapidly increased over the past 5 years (2011-2015) and the number of such researches more than doubled compared to the past (1996-2010). Based on the environmental field with generated association rules among the keywords, it was identified that the keyword 'general environment' was using 16 ICT-based technologies and 'climate' was using 14 ICT-based technologies.

• Journal of Intelligence and Information Systems
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• v.14 no.3
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• pp.59-76
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• 2008

In this paper, we propose an agent architecture called L-CAA that is quite effective in real-time dynamic environments. L-CAA is an extension of CAA, the behavior-based agent architecture which was also developed by our research group. In order to improve adaptability to the changing environment, it is extended by adding reinforcement learning capability. To obtain stable performance, however, behavior selection and execution in the L-CAA architecture do not entirely rely on learning. In L-CAA, learning is utilized merely as a complimentary means for behavior selection and execution. Behavior selection mechanism in this architecture consists of two phases. In the first phase, the behaviors are extracted from the behavior library by checking the user-defined applicable conditions and utility of each behavior. If multiple behaviors are extracted in the first phase, the single behavior is selected to execute in the help of reinforcement learning in the second phase. That is, the behavior with the highest expected reward is selected by comparing Q values of individual behaviors updated through reinforcement learning. L-CAA can monitor the maintainable conditions of the executing behavior and stop immediately the behavior when some of the conditions fail due to dynamic change of the environment. Additionally, L-CAA can suspend and then resume the current behavior whenever it encounters a higher utility behavior. In order to analyze effectiveness of the L-CAA architecture, we implement an L-CAA-enabled agent autonomously playing in an Unreal Tournament game that is a well-known dynamic virtual environment, and then conduct several experiments using it.