• Title/Summary/Keyword: Li Chan

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A Study on the Correlation between the Cold-damage Six-meridian disease of Qibo (岐伯六經病證) and the Sasang Constitutional Symptomatology (四象體質病證) (기백육경병증(岐伯六經病證)과 사상체질병증(四象體質病證)간의 상관관계 연구)

  • Lee, Jun-Hee
    • Journal of Sasang Constitutional Medicine
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    • v.33 no.1
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    • pp.1-21
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    • 2021
  • Objective The purpose of this study was to examine the correlation between the Cold-damage Six-meridian disease of Qibo (岐伯六經病證) and Sasang Constitutional Symptomatology (四象體質病證), presented in Discourse on the Origin of Eastern Medicine (醫源論) of Longevity and Life Preservation in Eastern Medicine (Donguisusebowon, 東醫壽世保元). Method The process of development from Cold-damage Six-meridian disease of Qibo (岐伯六經病證) to Six Meridians Physical Symptoms and Medicines (六經形證用藥) in the chapter Cold(寒門) of the Treasure Mirror of Eastern Medicine (Donguibogam, 東醫寶鑑) was investigated. And the correlation between Six Meridians Physical Symptoms and Medicines (六經形證用藥) and Sasang Constitutional Symptomatology (四象體質病證) was considered. Results and Conclusions 1. The Cold-damage Six-meridian disease of Qibo (岐伯六經病證) in the chapter Heat Treatise (熱論篇) of Basic Questions (素問) had evolved into Six Meridians Physical Symptoms and Medicines (六經形證用藥) in the chapter Cold(寒門) of the Treasure Mirror of Eastern Medicine (Donguibogam, 東醫寶鑑) through Book for Life Saving (Huorenshu, 活人書), a work of Zhu Gong (朱肱), Six Books on Cold Damage disease (Shanghanliushu, 傷寒六書), a work of Tao Hua (陶華) and Introduction to Medicine (YixueRumen, 醫學入門), a work of Li Chan (李梴). 2. The correlation between the Cold-damage Six-meridian disease of Qibo (岐伯六經病證) and Sasang Constitutional Symptomatology (四象體質病證) can be analyzed and understood through Six Meridians Physical Symptoms and Medicines (六經形證用藥) in the chapter Cold(寒門) of the Treasure Mirror of Eastern Medicine (Donguibogam, 東醫寶鑑). 3. Greater Yang meridian disease of Qibo (岐伯) is related to Soyangin early stage of Lesser-Yang Wind-Injury symptomatology and Soyangin early stage of Chest-Heat symptomatology, Yang Brightness meridian disease and Greater Yin meridian disease to Taeeumin Liver-Heat symptomatology, Lesser Yin meridian disease to Soyangin Chest-Heat symptomatology, Lesser Yang meridian disease to Soyangin early stage of Lesser-Yang Wind-Injury symptomatology and Reverting Yin meridian disease to Soeumin Reverting Yin symptomatology of Greater Yang disease.

Seismic behavior and failure modes of non-ductile three-story reinforced concrete structure: A numerical investigation

  • Hidayat, Banu A.;Hu, Hsuan-Teh;Hsiao, Fu-Pei;Han, Ay Lie;Sosa, Lisha;Chan, Li-Yin;Haryanto, Yanuar
    • Computers and Concrete
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    • v.27 no.5
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    • pp.457-472
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    • 2021
  • Reinforced concrete (RC) buildings in Taiwan have suffered failure from strong earthquakes, which was magnified by the non-ductile detailing frames. Inadequate reinforcement as a consequence of the design philosophy prior to the introduction of current standards resulted in severe damage in the column and beam-column joint (BCJ). This study establishes a finite element analysis (FEA) of the non-ductile detailing RC column, BCJ, and three-story building that was previously tested through a tri-axial shaking table test. The results were then validated to laboratory specimens having the exact same dimensions and properties. FEA simulation integrates the concrete damage plasticity model and the elastic-perfectly plastic model for steel. The load-displacement responses of the column and BCJ specimens obtained from FEA were in a reasonable agreement with the experimental curves. The resulting initial stiffness and maximum base shear were found to be a close approximation to the experimental results. Also, the findings of a dynamic analysis of the three-story building showed that the time-history data of acceleration and displacement correlated well with the shaking table test results. This indicates the FEA implementation can be effectively used to predict the RC frame performance and failure mode under seismic loads.

MARS-PD: Meridian Activation Remedy System for Parkinson's Disease

  • Miso S. Park;Chan-young Kim;In-woo Choi;In-cheol Chae;Wangjung Hur;SangSoo Park;Horyong Yoo
    • The Journal of Internal Korean Medicine
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    • v.44 no.1
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    • pp.1-11
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    • 2023
  • Objective: There are currently no disease-modifying medications or definite long-term sustainable interventions for patients with Parkinson's disease (PD), indicating an unmet treatment need. Our goal was to create a long-term sustainable intervention for PD patients that can be used in Korean medicine clinics. Methods: The Meridian Activation Remedy System (MARS) was created to stimulate a patient's 12 meridians and sinew channels using a combination of acupoint stimulation and exercise. The acupoints and motions used in MARS were selected through literature studies and expert advice. The methodologies were refined using observational and case studies. With slow and fast movements, the MARS intervention was intended to activate both slow- and fast-twitch muscle fibers. Intradermal acupuncture and motion that shift the center of gravity were employed to enhance the patient's balance and proprioception. In addition, the intervention included alternating movement exercises to address the complex cognitive decline commonly occurring in PD patients. Results: The following acupoints were chosen for the MARS intervention: bilateral Hegu (LI4), Houxi (SI3), Waiguan (TE5), Neiguan (PC6), Zhongchong (PC9), Yuji (LU10), Zusanli (ST36), Yanglingquan (GB34), Taichong (LR3), Kunlun (BL60), and Taixi (KI3). We also developed actions that can stimulate the body's 12 meridians. Conclusion: We developed the MARS intervention, which combines acupuncture and exercise, to address the unmet therapeutic needs of PD patients. We hope that with additional research, the MARS intervention can be set as an effective therapeutic program for PD patients.

Developing a BIM-Based Methodology Framework for Sustainability Analysis of Low Carbon High-Rise Buildings

  • Gan, Vincent J.L.;Li, Nan;Tse, K.T.;Chan, C.M.;Lo, Irene M.C.;Cheng, Jack C.P.
    • International conference on construction engineering and project management
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    • 2017.10a
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    • pp.14-23
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    • 2017
  • In high-density high-rise cities such as Hong Kong, buildings account for nearly 90% of energy consumption and 61% of carbon emissions. Therefore, it is important to study the design of buildings, especially high-rise buildings, to achieve lower carbon emissions in the city. The carbon emissions of a building consist of embodied carbon from the production of construction materials and operational carbon from energy consumption during daily operation (e.g., air-conditioning and lighting). An integrated analysis of both types of carbon emissions can strengthen the design of low carbon buildings, but most of the previous studies concentrated mainly on either embodied or operational carbon. Therefore, the primary objective of this study is to develop a holistic methodology framework considering both embodied and operational carbon, in order to enhance the sustainable design of low carbon high-rise buildings. The framework will be based on the building information modeling (BIM) technology because BIM can be integrated with simulation systems and digital models of different disciplines, thereby enabling a holistic design and assessment of low carbon buildings. Structural analysis program is first coupled with BIM to validate the structural performance of a building design. The amounts of construction materials and embodied carbon are then quantified by a BIM-based program using the Dynamo programming interface. Operational carbon is quantified by energy simulation software based on the green building extensible Markup Language (gbXML) file from BIM. Computational fluid dynamics (CFD) will be applied to analyze the ambient wind effect on indoor temperature and operational carbon. The BIM-based framework serves as a decision support tool to compare and explore more environmentally-sustainable design options to help reduce the carbon emissions in buildings.

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A review of DEM resolution based on flood inundation analysis (DEM 해상도에 따른 홍수범람해석 검토)

  • Lim, Jae Deok;Park, Su Hee;Park, Chan Hee;Yoo, Sang Yeon
    • Proceedings of the Korea Water Resources Association Conference
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    • 2022.05a
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    • pp.223-223
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    • 2022
  • 최근 도시지역의 홍수피해가 증가함에 따라 홍수방어대책이 중요해지고 있다. 제방 축조 및 배수시설 개선 등의 구조적 대책이 우선되어야 하나, 계획빈도 이상의 호우로 인한 피해 발생시 인명피해 및 재산피해를 최소화하기 위한 비구조적 대책 또한 중요한 실정이다. 본 연구에서는 도시지역의 비구조적 대책 수립을 위해 하천 제방 붕괴로 인한 홍수범람 해석을 수행하였다. 도시지역의 홍수범람 해석은 일반적으로 확산형의 흐름 특성을 가져, 홍수의 잠재성이 크다고 판단되는 도시지역에 대해 확산형 범람 해석을 통해 홍수의 전파양상을 심층적으로 검토할 수 있는 Flumen 모형을 적용하였다. "홍수위험지도 작성에 관한 지침(2020, 환경부)"에서는 2차원(확산형) 홍수범람 분석시 LiDAR 기반 1m급 DEM 자료를 권장하고 있으나, 영산·섬진강권역(제주도 포함) 내 1m급 DEM 자료는 약 11,320km2가 구축되어 전체면적(17,756km2) 대비 64%만 구축되어 도시지역 전체 적용에 한계가 있다. 본 연구에서는 도시지역과 농경지가 포함된 도시지역(농촌형 도심지역)을 대상으로 1m급 DEM과 5m급 DEM을 구분하여 2차원(확산형) 홍수범람 분석을 수행하였다. 도시지역으로는 지방하천 순천동천이 관류하는 순천시가지를 선정하였고, 농촌형 도심지역으로는 지방하천 광치천이 관류하는 남원시가지를 선정하였다. 2차원 홍수범람 해석을 위해 주요 지점별 파제 시나리오는 각 지구별 동일하게 작성하였으며, DEM 자료에 따른 검토 결과, 도시지역의 경우 지하차도 등과 같은 시설로 인한 차이가 발생하였으나, 농촌형 도시지역의 경우 DEM 해상도에 따른 침수양상 및 면적 차이가 크지 않은 것으로 검토되어 농촌형 도시지역의 경우 5m급 DEM 자료의 활용이 가능한 것으로 검토되었다. 추후 전국 지방·도시하천에 대한 홍수위험지도 제작이 완료된다면 홍수로 인한 침수피해에 대해 사전에 대비하고, EAP, 재해지도 제작, 수해방지대책 수립 등 관련 계획수립 시 기초자료로 활용이 가능할 것이다.

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Advancing Cardio-Oncology in Asia

  • Choon Ta Ng;Li Ling Tan;Il Suk Sohn;Hilda Gonzalez Bonilla;Toru Oka;Teerapat Yinchoncharoen;Wei-Ting Chang;Jun Hua Chong;Maria Katrina Cruz Tan;Rochelle Regina Cruz;Astri Astuti;Vivek Agarwala;Van Chien;Jong-Chan Youn;Jieli Tong;Joerg Herrmann
    • Korean Circulation Journal
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    • v.53 no.2
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    • pp.69-91
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    • 2023
  • Cardio-oncology is an emerging multi-disciplinary field, which aims to reduce morbidity and mortality of cancer patients by preventing and managing cancer treatment-related cardiovascular toxicities. With the exponential growth in cancer and cardiovascular diseases in Asia, there is an emerging need for cardio-oncology awareness among physicians and country-specific cardio-oncology initiatives. In this state-of-the-art review, we sought to describe the burden of cancer and cardiovascular disease in Asia, a region with rich cultural and socio-economic diversity. From describing the uniqueness and challenges (such as socio-economic disparity, ethnical and racial diversity, and limited training opportunities) in establishing cardio-oncology in Asia, and outlining ways to overcome any barriers, this article aims to help advance the field of cardio-oncology in Asia.

Estimation of Carbon Stock and Annual CO2 Uptake of Four Species at the Sejong National Arboretum - Pinus densiflora, Metasequoia glyptostroboides, Aesculus turbinata, Chionanthus retusus - (국립세종수목원 교목 4종의 탄소 저장량 및 연간 이산화탄소 흡수량 평가 - 소나무, 메타세쿼이아, 칠엽수, 이팝나무를 대상으로 -)

  • Hak Koo KIm;Yong Sik Hong;Yun Kyung Lim;I Seul Yun;Ki Seok Do;Chan Hyung Jung;Chi Mun Lee;Hoi Eun Roh;Sin Koo Kang;Chan-Beom Kim
    • Journal of Environmental Impact Assessment
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    • v.32 no.1
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    • pp.41-48
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    • 2023
  • This study was conducted to confirm the possibility of a new carbon stock in the Sejong National Arboretum, a major urban greenspace in Sejong-si. This study involved field and ground surveys of 1,336 trees, including 794 Pinus densiflora trees with a diameter at breast height (DBH) of above 5.5cm, which are the most planted in the Sejong National Arboretum, Chionanthus retusus 154 trees planted, Metasequoia glyptostroboides 216 trees, and Aesculus turbinata 172 trees as street trees. Measurements were performed from April to November. Based on the results of the survey, the carbon storage and annual carbon stock were calculated using the annual carbon stock estimation equation used in the forest carbon offset projects. As a result of comparing the carbon stock of the 12cm diameter class, which is the most distributed of four major trees, it was found in the order of C. retusus (0.0136tC/tree), P. densiflora (0.0126tC/tree), M. glyptostroboides (0.0092tC/tree), and A. turbinata (0.0076tC/tree). In addition, the field survey measurement data compared with terrestrial LiDAR measurement data for 20 trees showed a difference of 10.0cm in tree height and 1.7cm in diameter at breast height (p<0.05). In the future, additional carbon stock and annual uptake of other species planted in the arboretum are expected to promote the carbon uptake effect of the arboretum and contribute to the achievement of the national NDC. In the long term, it is also necessary to develop the carbon uptake factor of trees and shrubs mainly used to calculate the exact carbon uptake amount of trees mainly used in urban forests and gardens.

Magnetic Tunnel Junctions with AlN and AlO Barriers

  • Yoon, Tae-Sick;Yoshimura, Satoru;Tsunoda, Masakiyo;Takahashi, Migaku;Park, Bum-Chan;Lee, Young-Woo;Li, Ying;Kim, Chong-Oh
    • Journal of Magnetics
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    • v.9 no.1
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    • pp.17-22
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    • 2004
  • We studied the magnetotransport properties of tunnel junctions with AlO and AlN barriers fabricated using microwave-excited plasma. The plasma nitridation process provided wider controllability than the plasma oxidization for the formation of MTJs with ultra-thin insulating layer, because of the slow nitriding rate of metal Al layers, comparing with the oxidizing rate of them. High tunnel magnetoresistance (TMR) ratios of 49 and 44% with respective resistance-area product $(R{\times}A) of 3 {\times} 10^4 and 6 {\times} 10^3 {\Omega}{\mu}m^2$ were obtained in the Co-Fe/Al-N/Co-Fe MTJs. We conclude that AlN is a hopeful barrier material to realize MTJs with high TMR ratio and low $R{\times}A$ for high performance MRAM cells. In addition, in order to clarify the annealing temperature dependence of TMR, the local transport properties were measured for Ta $50{\AA} /Cu 200 {\AA}/Ta 50 {\AA}/Ni_{76}Fe_{24} 20 {\AA}/Cu 50 {\AA}/Mn_{75}Ir_{25} 100 {\AA}/Co_{71}Fe_{29} 40 {\AA}/Al-O$ junction with $d_{Al}= 8 {\AA} and P_{O2}{\times}t_{0X}/ = 8.4 {\times} 10^4$ at various temperatures. The current histogram statistically calculated from the electrical current image was well in accord with the fitting result considering the Gaussian distribution and Fowler-Nordheim equation. After annealing at $340^{\circ}C$, where the TMR ratio of the corresponding MTJ had the maximum value of 44%, the average barrier height increased to 1.12 eV and its standard deviation decreased to 0.1 eV. The increase of TMR ratio after annealing could be well explained by the enhancement of the average barrier height and the reduction of its fluctuation.

Evaluation of Salt-Tolerance Plant for Improving Saline Soil of Reclaimed Land (간척지 토양개량을 위한 내염성 식물의 활용성 평가)

  • Lee, Kyeong-Bo;Kang, Jong-Gook;Li, Jumei;Lee, Deog-Bae;Park, Chan-Won;Kim, Jae-Duk
    • Korean Journal of Soil Science and Fertilizer
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    • v.40 no.3
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    • pp.173-180
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    • 2007
  • Reclaimed tidal area is a great agricultural resource in the world. Improvement and utilization of reclaimed soil is an important measure for expanding land resource. This study was conducted to evaluate relative salt-tolerance of plants and its effect for improving saline soil. Eighteen tolerance plants were selected from China, Pakistan and Korea the climate of which is different. The emergence of different varieties in reclaimed soil was in order as FL478>Barnyard grass>Pokkali>Atriplex>Sesbania>Rumex>Alfalfa>Tall Fescue>Ryegrass>Sudan grass. Four varieties, Barnyard grass, Sesbania, Atriplex and Limonium were selected for soil improvement in reclaimed land. Cultivation of Sesbania, Barnyard grass and Atriplex were good to soil physico-chemical quality. Also these plants increased soil organic matter contents and reduced soil salt concentration. Organic matter contents of cultivated soils of Sesbania, Barnyard grass and Atriplex were $4.10g\;kg^{-1}$, $4.60g\;kg^{-1}$ and $2.81g\;kg^{-1}$ respectively. On the other hand organic matter content of uncultivated soils was $2.65g\;kg^{-1}$. As Sesbania and Barnyard grass were applied to cultivated soil like green manure, bulk density improved from $1.42Mg\;m^{-3}$ to $1.39Mg\;m^{-3}$.

Effects of Dermal Cell Combination on the Formation of Basement membrane and Epidermis in Skin Equivalents (진피세포의 조성이 인공피부의 기저막과 표피형성에 미치는 영향)

  • Li, Hai-Lan;Jeong, Hyo-Soon;Kim, Jan-Di;Yun, Hye-Young;Baek, Kwang-Jin;Kwon, Nyoun-Soo;Min, Young-Sil;Park, Kyoung-Chan;Kim, Dong-Seok
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.38 no.3
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    • pp.219-224
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    • 2012
  • European Union prohibited the marketing of cosmetic products containing constituents that have been examined through animal experiments. Thus, non-animal test models are needed to replace animal experiments. The reconstructed skin models are important as a test system for cosmetic, pharmaceutical, and medical device safety testing. In the present study, we tried to develop an optimal skin equivalent model containing basement membrane and epidermis. For this purpose, we used mesenchymal stem cells (MSCs) and/or preadipocytes as well as fibroblasts as the dermal matrix cells. The formation of basement membrane and epidermis was verified by immunohistochemical stains. Among various models, the epidermis was thickest when MSCs were used in the dermal matrix. Furthermore, PCNA and involucrin distribution showed that dermal matrix with MSCs resembled human skin. Therefore, skin equivalents with MSCs could be developed as a non-animal test model to replace animal experiments.