• 대한지역사회영양학회지
• /
• 제26권3호
• /
• pp.211-227
• /
• 2021

Objectives: We aimed to examine the association between the relative preference for vegetables and meat and cancer incidence, in a population-based retrospective cohort in Korea. Methods: We included 10,148,131 participants (5,794,124 men; 4,354,007 women) who underwent national health screening between 2004 and 2005 from the National Health Information Database of the National Health Insurance Service (NHIS-NHID). Participants were asked whether they preferred consuming 1) vegetables more often, 2) both vegetables and meat or 3) meat more often. Participants were followed up to Dec. 31, 2017. All cancer and eighteen common cancer cases were identified through the code from the International Classification of Diseases, 10th revision. We estimated sex-specific relative risks and 95% confidence intervals, adjusting for age, body mass index, alcohol consumption, smoking, physical activity, and income level. Results: During an average follow-up of 12.4 years, 714,170 cancer cases were documented. In men, consuming meat more often was associated with lower risk of esophageal, liver, and stomach cancers, but higher risk of lung and kidney cancers. Consuming both vegetables and meat was associated with higher risk of prostate cancer, but with lower risk of esophageal, liver, and stomach cancers in men. In women, consuming meat more often was associated with a higher risk of colorectal cancer and breast, endometrial, and cervical cancers diagnosed before the age of 50. Consuming both vegetables and meat was associated with lower risk of liver cancer in women. Conclusions: Our study suggests a potential link between vegetable and meat intake and cancer incidence in the Korean population. Further investigation on the association between the intake of specific types of vegetables and meat and cancer risk in Korean prospective cohort studies is needed.

• 가정과삶의질연구
• /
• 제7권1호
• /
• pp.97-118
• /
• 1989

The purpose of this study is to clarify the definition of middle age, to compare the different perspectives about mid-life crisis, and to identify the variables that cause the mid-life crisis of men and women.. For this purpose reviewing literatures and emprical research were conducted. For the emprical research, Mid-life Crisis Scale, Mid-life Indentity Scale, Family Relation Scale. Health Scale and Religious Scale were developed. The Sample was selected form the men and women living in Seoul, whose age is from 40 to 59 , and whose last child is older than 13 years of age. Among 820 respondents 218 men and 442 women were finally selected as datum sources. The data were analyzed by the statistical method such as the factor analysis frequency distribution, percentile, ANOVA, Pearson's correlation and regression analysis. The main results were as follows; 1) Men and women experience mid-life crisis some extent. The mid-life crisis score for men is 33.60 and 35.0 for women. This implies women reveal significantly higher crisis than men. As for women's mid-life crisis. self-awaring age, education, income, husband's occupation, employment status of wife and occupational status of wife have a significant influence Expecially employment status of wife seemed to interact with sex, husband's occupation and educational level of wife. however status of child, family pattern, son's existence are not as important an influence on mid-life crisis. 3) Among the psychological variables, work identity and physical identity have the strong influence on the mid-life crisis of men and women, It implies that mid-life crisis si lower when one has higher work identity and physical identity. 4) Mid -life crisis of men and women is influenced significantly according to family relation variables and health variables. It reveals that the better one's family relations and health sate, the lower one's mid-life crisis is. However menopause and the years after menopause do not influence on the mid-life crisis of women. 5) Mid-life crisis of women differs significantly according to the kind of religion and religious activity. That is mid-life crisis of women is lower when she believes in Protestantism and Catholicism and participate in more religious activity. Mid-life crisis of men is not significantly influenced by religious variables. After all among the five categories of variables that related to mid-life crisis, psychological variables-especially work identity and physical identity are observed to have the strongest degree of significance.

• 한국산업보건학회지
• /
• 제10권1호
• /
• pp.160-169
• /
• 2000

Daily indoor and outdoor nitrogen dioxide ($NO_2$) concentration for 30 days were measured in 28 houses with questionnaire of housing characteristics in Brisbane, Australia. Using mass balance equation and regression analysis, penetration factors and source strength factors were calculated. The penetration factors of 27 houses except one house were between zero and 1, though penetration factor should be between zero and 1 by means of mass balance equation. Relationship between indoor and outdoor concentrations in each 27 house was calculated using regression analysis. According to the obtained linear regression equation, the slope means penetration factor and the intercept means source strength factor. Calculated mean and standard deviation of coefficients of determination ($R^2$) in electric and gas range houses were $0.70{\pm}0.13$ and $0.57{\pm}0.21$, respectively. The source strength factors were more than zero in 27 houses. Mean and standard deviation of slopes in electric and gas range houses were $0.65{\pm}0.18$ and $0.56{\pm}0.12$, respectively. Mean and standard deviation of intercepts in electric and gas range houses were $1.49{\pm}1.25$ and $5.77{\pm}3.55$, respectively. Air exchange rate and source strength were calculated from penetration factor and source strength factor, respectively. Geometric mean and standard deviation of calculated air exchange rates in 27 houses were $1.1/hr{\pm}1.5$. Presence of gas range was the most significant factor contributing to indoor $NO_2$ level in house characteristics (p=0.003). In gas range houses, source strengths ranged from 4.1 to $33.1cm^3/hr{\cdot}m^3$ with a mean $12.7cm^3/hr{\cdot}m^3$ and a standard deviation 9.8. The source strengths of gas range houses were significantly different from those of electric range houses by t-test (p<0.001)

• 한국환경보건학회지
• /
• 제43권4호
• /
• pp.247-256
• /
• 2017

Objectives: The deaths of Korean victims exposed to the disinfectant CMIT/MIT have remained unresolved. This is mainly due to a lack of concordance between the few available toxicity tests and the abundant epidemiological data, making it difficult to establish a cause-and-effect relationship. Therefore, this study was carried out to investigate any potential associations between CMIT/MIT exposure and death. Methods: Groups of experimental and control C57BL/6 mice were instilled (in the trachea) with chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) using a visual instillobot. CMIT/MIT was instilled over a period of three days and eight weeks, respectively, to achieve acute and chronic exposures. A threshold dose-response model was applied for estimating the threshold level as one line of evidence for a causal association between CMIT/MIT and death. Results: An acute exposure of 1.2 mg ai/kg/day of CMIT/MIT was estimated to reflect the threshold for death. The dose-response curve with this threshold showed a very steep slope and a narrow range of CMIT/MIT exposures. The narrow range of CMIT/MIT exposures, in particular, indicated an evident boundary between survival and death, thus implicating a strong causal association. A similar threshold dose-response relationship observed following acute exposure was also seen following chronic exposure to CMIT/MIT. Airborne disinfectant exposure was visible as minimal or mild lung damage with no fibrosis, as shown by histopathological tests. However, many observations are considered to be functional respiratory tract or lung failure due to death, as observed in necropsies of the mice that died due to CMIT/MIT exposures. Conclusions: There are two strong lines of evidence for a causal association between death and CMIT/MIT exposure: 1) The threshold dose-response curve, with a very steep slope and a narrow range of CMIT/MIT exposures showing a visible boundary between survival and death; and 2) many cases of functional respiratory or lung failure.

• 한국산업보건학회지
• /
• 제6권2호
• /
• pp.187-201
• /
• 1996

This study was to evaluate the efficiency of diffusive monitor using activated carbon fiber(ACF, KF-1500) in measuring airborne organic solvents. The following characteristics were identified and studied as critical to the performance of diffusive monitor; recovery, sampling rate, face velocity, reverse diffusion and storage stability. For the evaluation of the performance of this monitor, MIBK, PCE, toluene were used as organic solvents. In the sampling rate experiments, eight kinds of solvents (n-hexane, MEK, DIBK, MCF, TCE, CB, xylene, cumene) as well as the above solvents were used. The results were as follows: 1. The desorption efficiencies(DE's) of ACF diffusive monitor ranged from 83 % to 101 %. In contrast, those of coconut shell charcoal ranged from 78 % to 102 %. Especially, the DE's of ACF for the polar solvents such as MEK were superior to those of charcoal. 2. Experimental sampling rates on ACF were average 42ml/min(37-46ml/min) for 11 organic solvents at $24{\pm}2^{\circ}C$, $50{\pm}5%RH$. However ideal sampling rates(DA/L) were 33 % higher than experimental sampling rates. 3. The initial response(15~16 min) of the testing monitor was 2 times higher than the actual concentration determined by the reference methods at $24{\pm}2^{\circ}C$, $8{\pm}5%RH$ and $80{\pm}5%RH$. Within 1 hours, the curve reached a linear horizontal line at low humidity condition. But sampling efficiencies decreased with respect to time at high humidity condition. And sampling efficiencies were higher at high humidity condition than low humidity condition for MIBK. 4. At very low velocity (less than 0.02 m/sec), the concentration of ACF diffusive monitor were poorly estimated. But ACF diffusive monitor were not affected at higher velocity(0.2 m/sec-0.6 m/sec). 5. There was no significant reverse diffusion when the ACF monitors were exposed to clean air for 2 hours after being exposed for 2 hours at the level of 1 TLV. 6. There was no significant sample loss during 3 weeks of storage at room temperature and 5 weeks of storage at refrigeration.

• Journal of Preventive Medicine and Public Health
• /
• 제5권1호
• /
• pp.49-56
• /
• 1972

During the Period from 22th to November 26th, 1971, An Epidemiological Survey was performed on the Accident which was occurred by Leakage of Chloride Gases in A Chemical Industry, one of Wul San Industrial Areas. The obtained results were as follows; 1. The largest damage was observed at Yeo Cheon Dong, 5.38 Km2 in Area and 8,192 in the Residents. 2. By the age distribution of Yeo Cheon Dong, The largest damaged area resulting from chloride accident, the age group of between 10 and 39 was highly occupied with 55.2% Of all Yeo Cheon residents. 3. The number of patient was 436 totally, 198 in male and 238 in female. 4. By the age group distribution of the patient, in case of male, the largest group was under 20 age (96) and female, between 20 and 40 age group. 5. By the educational level of the patient, No-Education group was 116 (26.6%), and primary school, middle school and high school were respectively 168 (38.5%), 68 (15.6%) and 12 (2.8%). 6. By the occupational distribution of the patient, No-Occupation group was 49.7%, students and agriculture were respectively 14.4% and 8.1%. 7. By the complaints of the patient, most of all were for respiratory tract, those are coughing (56.9%), chest tightness (35.6%), sore throat (24.8%), and so forth. 8. By the injured domestic animal, the Dog was most highly injured with 46.2%.

• 한국산업보건학회지
• /
• 제7권2호
• /
• pp.289-297
• /
• 1997

Work-related low back pain(below LBP) is one of the major cause of morbidity, disability, limitation of activity and economic loss. Therefore the work-related LBP is one of the major issue in the field of industrial safety and health. This study was performed for detecting the risk factors and proposing the effective control programs of work-related LBP. The subjects were male workers employed at the welding and metal factory. The data was collected by self-reported questionnaire, interview and checking abdomen muscular and grasping power for two days on October, 1993. The contents of questionnaire were as follow: the experience of LBP, general characteristics, physical characteristics, employment status, type of work and working environment. The number of cases was 104 with a history of work-related LBP, so the prevalence of work-related LBP was 35.0%, and the number of controls was 140 without any history of LBP. As a result, marital status, educational level, abdomen muscular power, tenure, category of job, satisfaction of job, working posture, satisfaction for table and chair and lifting materials showed a statistical significance between the case and control groups. 284 Lifting jobs were quantified by NIOSH lifting equation method and ergonomic computer modelling methods. There were no significant differences in the action limit and disc compression force between group with LBP and without LBP. But in the lifting frequency and cumulative disc compression force there were significant differences. Therefore work-related LBP should be prevented by the ergonomic and environmental control.

• 한국건축시공학회지
• /
• 제13권1호
• /
• pp.75-83
• /
• 2013

The prevention of safety accidents can be achieved through Harvey's 3E's: Engineering, Enforcement, and Education. On construction sites, however, enforcement and engineering did not prove to be valid ways of reducing the number of safety accidents, as enforcement and engineering have failed to overcome and/or supplement the realistic limits regarding the relatively lower education levels of construction workers and the communication issues with foreign workers. On the other hand, safety education can enable the advancement of safety management by enhancing the educational contents and their methods of delivery. To improve the efficiency of safety education via educational contents, this research conducted a qualitative and quantitative analysis on the validity of the newly educational contents by overviewing possible accident types in different work phases. Of the accident types identified by the qualitative analysis, neither highly important nor insignificant accident types were found, yet all the suggested types are found to be required. In addition, this study did not find any significant differences in the occurrence probability of safety accidents related to the level of importance of each type of accident. The qualitative analysis in this research verified that the suggested accident types can be valid, educational material that can take into account future safety accidents.

• Journal of Preventive Medicine and Public Health
• /
• 제45권4호
• /
• pp.251-258
• /
• 2012

Objectives: The purpose of this paper was to elucidate the potential methylation levels of adjacent normal and cancer tissues by comparing them with normal colorectal tissues, and to describe the correlations between the methylation and clinical parameters in Korean colorectal cancer (CRC) patients. Methods: Hypermethylation profiles of nine genes (RASSF1, APC, $p16^{INK4a}$, Twist1, E-cadherin, TIMP3, Smad4, COX2, and ABCB1) were examined with 100 sets of cancer tissues and 14 normal colorectal tissues. We determined the hypermethylation at a given level by a percent of methylation ratio value of 10 using quantitative methylation real-time polymerase chain reaction. Results: Nine genes' hypermethylation levels in Korean CRC patient tissues were increased more higher than normal colorectal tissues. However, the amounts of $p16^{INK4a}$ and E-cadherin gene hypermethylation in normal and CRC tissues were not significantly different nor did TIMP3 gene hypermethylation in adjacent normal and cancer tissues differ significantly. The hypermethylation of TIMP3, Ecadherin, ABCB1, and COX2 genes among other genes were abundantly found in normal colorectal tissues. The hypermethylation of nine genes' methylation in cancer tissues was not significantly associated with any clinical parameters. In Cohen's kappa test, it was moderately observed that RASSF1 was related with E-cadherin, and Smad4 with ABCB1 and COX2. Conclusions: This study provides evidence for different hypermethylation patterns of cancer-associated genes in normal and CRC tissues, which may serve as useful information on CRC cancer progression.

• The Journal of Korean Physical Therapy
• /
• 제30권1호
• /
• pp.29-34
• /
• 2018

Purpose: This study aimed to systematically analyze the reliability and validity of Korean versions of mobility and gait assessment tools for patients with stroke. Methods: Two reviewers conducted an independent literature search and systematically reviewed the literature. Literature published until June of 2017 was searched using search engines for electronic databases. The 2 reviewers reviewed the title and abstract of each article. Among the articles examined, we read the full text of those judged to be suitable for our study. We classified the selected data into research methods and results. The determination was made through mutual agreement. Results: The reviewers selected 5 articles related to the purpose of this study. The DGI was found to be moderately associated with BBS, 10MWT, and TUG in intra-rater reliability (ICC=0.92), inter-rater reliability (ICC=0.88), and concurrent validity tests. The FGA demonstrated a high level of reliability with intra-rater (ICC=0.92-0.95) and inter-rater reliability (ICC=0.91, 0.95). The intra-rater reliability of the RMI was high at ICC=0.98. Its concurrent validity showed a high association with STREAM and BI. The intra-rater reliability of the MAS was ICC=0.75-0.99. Its inter-rater reliability was very high, exceeding 0.99. The inter-rater reliability of the Tinetti-gait Scale was ICC=0.91, and its concurrent validity was moderately associated with the DGI, 10WMT, OLST, FM-L/E, and STS. Conclusion: The results of this study revealed that the reliability and validity of the Korean versions of the mobility and gait assessment tools were high.