• Korean Journal of Pharmacognosy
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• v.51 no.1
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• pp.65-69
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• 2020

Five known flavonoid glycosides were isolated from the aerial parts of Lespedeza juncea. Using various spectral data, we found the structures of the isolates to be 6"-O-acetylisovitexin (1), afzelin (2), vitexin (3), isovitexin (4), and, kaempferol-3-O-robinobioside (5). All compounds were isolated for the first time from this plant.

• Korean Journal of Plant Taxonomy
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• v.38 no.4
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• pp.547-555
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• 2008

Two naturalized plants of Lespedeza from Korea are reported. L. lichiyuniae T. Nemoto, H. Ohashi & T. Itoh is similar to L. cuneata (Dum. Cours.) G. Don. and L. juncea (L. .f.) Pers. in morphology, but the species differs from them by pink or purple flowers and the under surface of leaflets and cleistogamous pods with densely hairs. L. davidii Franchet is distinguished by distinctly large leaflets from the other Korean Lespedeza and by plants covered with densely tomentose hairs from the Korean species of subgenus Macrolespedeza. In Korea two plants are found on the parks or roads prepared recently.

• Journal of Practical Agriculture & Fisheries Research
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• v.19 no.1
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• pp.99-108
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• 2017

It is Lespedeza cuneata. G. don used as a remedy for cough, asthma, premature ejaculation and so on, though it has been used for a long time. In order to investigate the possibility of using Lespedeza cuneata. G. don as a raw material for functional food, we examined useful substances through analysis. In the study, 124 useful substances were analyzed and 84 of them were found to be functional. In 6 species, 6 of them were found to be functional and 5 of them were functional. In the present study, the other useful substance, D-pinitol, also confirmed its functionality. Potassium isolespedezate and Potassium lespedezate act as antibiotics, Trifolin acts as an antibiotic and hepatoprotectant, and Vitexin acts as a hepatoprotectant. D-pinitol has shown excellent efficacy in patients with prediabetic and insulin-resistant diabetes. As it contains a large amount of useful substances, it can be utilized as a highly functional food.

• Korean Journal of Pharmacognosy
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• v.39 no.1
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• pp.68-73
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• 2008

The present study represents the screening of the protective effects of herbal methanolic extracts from Baekdu mountain against tacrine-induced cytotoxicity in HepG2 cells. Tacrine is an acetylcholinesterase inhibitor, and used for the treatment of Alzheimer's disease. However, administration of tacrine for the treatment of Alzheimer's disease results in a reversible hepatotoxicity in 30-50% of patients, consequently limiting clinical use. Therefore, studies for natural products with protective effect on the tacrine-induced hepatotoxicity would be valuable as providing potential therapeutic use. 109 plant sources were collected in Baekdu mountain, and extracted with methanol. These extracts had been screened the protective effects against tacrine-induced cytotoxicity in HepG2 cells at the 100 and 300 ${\mu}g/ml$. Of these, ten methanolic extracts, roots of Ampelosis japonica, aerial parts of Berberis amurensis, aerial parts of Sedum aizoon, aerial parts of Lespedeza tomentosa, aerial parts of Lespedeza juncea, aerial parts of Hypenricum ascyron, stem barks of Syringa reticulata, fruits of Gleditsia japonica, aerial parts of Chamaenerion angustifolium, branches of Ginkgo biloba, showed significant protective effects against tacrine-induced cytotoxicity in HepG2 cells.

• Korean Journal of Pharmacognosy
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• v.39 no.4
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• pp.335-340
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• 2008

Diabetes mellitus is metabolic disorder characterized by hyperglycemia caused by insufficient insulin secretion or insulin receptor insensitivity to endogenous insulin. It is well-known that hyperglycemia is one of the main causes of oxidative stress in both type 1 and 2 diabetes. Oxidative stress is related by death of pancreatic ${\beta}$ cell and dysfunction of ${\beta}$ cell. Although ${\beta}$ cell death or dysfunction is induced by many substances or molecules, increased evidences that oxidative stress plays a crucial role in ${\beta}$ cell death or dysfunction. Considering the importance of oxidative stress in the pathogenesis of diabetes mellitus, we investigated the cytoprotective effects against hydrogen peroxide-induced oxidative stress in pancreatic ${\beta}$ cell line RIN-m5F cell. 110 Plant sources were collected in Mt. Baek-du, and extracted with methanol. These extracts had been screened the protective effects against hydrogen peroxide-induced oxidative damage in RIN-m5F cells at 50 and 200 ${\mu}g$/ml. Of these, ten methanolic extracts, aerial part of Erigenron cannadensis, aerial part of Lespedeza juncea, whole plant of Alopecurus aequalis, fruit of Lycium chinense, leaf of Morus alba, rhizome of Polygonatum odoratum, root of Ampelosis japonica, whole plant of Ranunculus japonicus, aerial part of Polygonum sieboldii, rhizome of Arisaema amurense var. violaceum showed significant protective effects against hydrogen peroxide-induced oxidative damage in pancreatic ${\beta}$ cell line RIN-m5F cell.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.15 no.4
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• pp.23-40
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• 2012

The vascular plants of major sites in Changwon-si were listed 456 taxa (9.3% of all 4,881 taxa of vascular plants); 112 families, 293 genera, 371 species, 2 subspecies, 66 varieties and 17 forms. The vascular plants of Changwon-cheon were listed 133 taxa, Junam reservoir were listed 90 taxa, Seongju-sa were listed 293 taxa, and Yungji park were listed 164 taxa. Divided into 456 taxa; woody plants were 160 taxa (35.1%) and herbaceous plants were 296 taxa (64.9%). Furthermore, therophytes (Th) were 111 taxa (24.3%), hemicryptophytes (H) were 75 taxa (16.4%), megaphanerophytes (MM) were 63 taxa (13.8%) showed high proportional ratio in life form. Based on the list of rare plants by the Korea Forest Service and Korea National Arboretum, 10 taxa (1.8% of all 571 taxa of rare plants); Aristolochia contorta (LC), Euryale ferox (VU), Melothrua japonica (LC), Utricularia pilosa (CR), Hydrocharis dubia (LC), Carex idzuroei (DD), Acorus calamus var. angustatus (LC), etc. Based on the list of endemic plants by the Korea National Arboretum, 10 taxa (3.0% of all 328 taxa of endemic plants); Salix pseudolasiogyne, Philadelphus incanus, Indigofera koreana, Lespedeza ${\times}$ maritima, Stewartia pseudocamellia, Weigela subsessilis, Carex okamotoi, etc. Based on the list of specific plants by floral region were total 43 taxa (4.0% of all 1,071 taxa of specific plants); 4 taxa (Euryale ferox, Hydrocharis dubia, Carex idzuroei, etc.) in class IV, 9 taxa (Ilex crenata, Acer palmatum, Stewartia pseudocamellia, Melothria japonica, Fatsia japonica, etc.) in class III, 3 taxa (Caltha palustris var. membranacea, Nymphoides indica, etc.) in class II, 26 taxa (Cyrtomium fortunei, Chloranthus japonicus, Quercus variabilis, Ulmus parvifolia, Aphananthe aspera, etc.) in class I. Based on the list of naturalized plants, 48 taxa (Rumex crispus, Chenopodium album var. album, Amaranthus patulus, Phytolacca american, Brassica juncea var. integrifolia, Potentilla paradoxa, Robinia pseudoacacia, Euphorbia maculata, Oenothera odorata, Cuscuta pentagona, Veronica persica, Plantago lanceolata, Diodia teres, Helianthus tuberosus, Dactylis glomerata, etc.), naturalization rate was 10.5% of all 456 taxa of vascular plants and urbanization index was 15.0% of all 321 taxa of naturalized plants. Ecosystem disturbing wild plants were 3 taxa (Rumex acetocella, Solanum carolinense, Ambrosia artemisiifolia).

• Korean Journal of Plant Taxonomy
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• v.49 no.3
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• pp.224-239
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• 2019

Species identification for the Korean tribe Desmodieae was conducted using the DNA barcoding genes rbcL, matK (from chloroplast DNA) and ITS (from nuclear ribosomal DNA). A total of 25 taxa (n = 75) in five genera were sequenced, and neighbor-joining trees were constructed using different combinations of DNA barcodes. When comparing these phylogenetic trees, a tree with all loci combined (rbcL + matK + ITS) showed the highest rate of identification success (72%). On this tree, two subtribes and five genera within the tribe were supported as monophyletic. In the Desmodiinae clade, Desmodium and Hylodesmum were more closely related to each other than to Ohwia. In the Hylodesmum clade, H. oldhamii was found to be a sister to H. podocarpum complex, and all taxa within the complex were identified successfully. Subsp. fallax, regarded as a variety of subsp. oxyphyllum, is closely clustered with subsp. podocarpum. Although var. mandshuricum has been regarded as a synonym of var. oxyphyllum, this taxon is supported as a distinct variety. For the Lespedezinae clade, all species of Kummerowia were monophyletic, while nine of 16 Lespedeza taxa were identified successfully. In particular, the resolution of Macrolespedeza (28.5%) was lower than that of Junceae (77.8%). Among the Lespedeza taxa, L. cuneata was distinguishable from L. lichiyuniae, despite morphological similarities. It has been suggested that both L. maritima and L. inschanica are hybrids. The former is thought to be an independent species. While it is difficult to determine whether the latter originated via hybridization, this study showed that it is closely related to L. juncea.