• International Journal of Highway Engineering
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• v.11 no.1
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• pp.195-201
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• 2009

In this paper, the critical strains for pavement design were calculated from both Layered Elastic Program (LEP) and Finite Element Method (FEM) and the case studies which give similar critical responses were compared. Although FEM has been realized as a superior model, LEP is more favorable to pavement design due to its simplicity and thus, the technique to calculate the correct critical responses using LEP is significant. This study showed that KENLAYER can possibly estimate the critical responses close to ones obtained from TTIPAVE, which considers nonlinear cross-anisotropic behavior of unbound base materials, by adjusting the stress point locations.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.12
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• pp.1930-1939
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• 2020

Objective: This study was conducted to investigate the differences in several serum adipokines in perinatal dairy cows with type I and II ketosis, and the correlations between these adipokines and the two types of ketosis. Methods: Serum adiponectin (ADP), leptin (LEP), resistin, tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) levels, and energy balance indicators related to ketosis were measured. Type I and II ketosis were distinguished by serum glucose (Glu) and Y values and the correlations between adipokines in the two types of ketosis were analyzed. Results: β-Hydroxybutyric acid of type I ketosis cows was significantly negatively correlated with insulin (INS) and LEP and had a significant positive correlation with serum ADP. In type II ketosis cows, ADP and LEP were significantly negatively correlated, and INS and resistin were significantly positively correlated. Revised quantitative INS sensitivity check index (RQUICKI) values had a significantly positive correlation with ADP and had a very significant and significant negative correlation with resistin, TNF-α, and IL-6. ADP was significantly negatively correlated with resistin and TNF-α, LEP had a significantly positive correlation with TNF-α, and a significantly positive correlation was shown among resistin, IL-6, and TNF-α. There was also a significant positive correlation between IL-6 and TNF-α. Conclusion: INS, ADP, and LEP might exert biological influences to help the body recover from negative energy balance, whereas resistin, TNF-α, and IL-6 in type II ketosis cows exacerbated INS resistance and inhibited the production and secretion of ADP, weakened INS sensitivity, and liver protection function, and aggravated ketosis.

• The Journal of Korea CHUNA Manual Medicine
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• v.3 no.1
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• pp.31-41
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• 2002

Objectives : To study that lateral epicondylitis(tennis elbow) is related with cervical spondylosis. Subjects : The study was composed of 25 patients of lateral epicondylitis(LEP group) and 25 normal control group(CON group). Method : Simple radiologic scale was compared such as cervical lordotic angle, grading for disc degeneration. Pavlov ratio and Intervertebral body Index Results : Cervical lordotic angle and disc degeneration is not significantly different. And Pavlov ratio and intervertebral body index is significantly decrease in the LEP group. Conclusion : The cervical spondylosis is related with ocuuring lateral epicondylitis.

• Korean Journal of Veterinary Pathology
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• v.3 no.2
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• pp.93-94
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• 1999

Spontaneous hydronephrosis was found in a 19 month-old female C57BL/KsJ-Lep $r^{db}$ / Lep $r^{db}$ mouse. We described the gross and histological appearance of spontaneous in db mouse The left kidney was dilated and filled with urine. Microscopically the renal pelvis was remarkedly dilated and the renal cortex and renal papilla were flattened.

• Journal of the Korea Society of Computer and Information
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• v.22 no.7
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• pp.47-54
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• 2017

Recently, correlation filter based trackers have shown excellent tracking performance and computational efficiency. In order to enhance tracking performance in the correlation filter based tracker, search area which is image patch for finding target must include target. In this paper, two methods to discriminatively represent target in the search area are proposed. Firstly, search area location is estimated using pyramidal Lucas-Kanade algorithm. By estimating search area location before filtering, fast motion target can be included in the search area. Secondly, we investigate multi-channel Local Edge Pattern(LEP) which is insensitive to illumination and noise variation. Qualitative and quantitative experiments are performed with eight dataset, which includes ground truth. In comparison with method without search area estimation, our approach retain tracking for the fast motion target. Additionally, the proposed multi-channel LEP improves discriminative performance compare to existing features.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2018.11a
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• pp.124-127
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• 2018

넓은 동적 영역 (High Dynamic Range: HDR) 이미지는 주관적 화질 측면에서 우수하지만 대부분의 디스플레이는 좁은 동적 영역 (Low Dynamic Rang e: LDR) 만 지원이 가능하다. 본 논문에서는 이를 해결하기 위해서 톤 매핑 기법 (Tone Mapping Operator: TMO) 을 사용하여 넓은 동적 영역을 압축하여 수행한다. 기존의 지역 에지 보존 (Local Edge Preserving: LEP) 필터를 적용한 이미지결과는 에지를 보존하지만, 스케일의 분해 과정 중 디테일의 손실이 발생되었다. 본 논문에서는 이미지 변화도를 기반으로 디테일을 보존하는 알고리듬을 제안한다. LEP 필터가 적용되기 전에 이미지의 변화도와 동적 영역이 압축된 후의 이미지에 대한 변화도의 차이만큼 가중하여 디테일을 보존함으로써 주관적 화질을 향상시켰다.

• Journal of Microbiology and Biotechnology
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• v.17 no.8
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• pp.1316-1323
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• 2007

In order to induce high levels of protein secretion, we have constructed a recombinant plasmid, designated pBP244, into which was incorporated key components of the type-II See-dependent secretion system, including LepB (signal peptidase), SecA (ATPase), and SecB (chaperone). The biological activities of the LepB, SecA, and SecB components expressed from genes harbored by pBP244 appeared to play their normal roles. In order to evaluate the protein secretion, a pspA (Streptococcus $\underline{p}neumoniae\;\underline{s}urface\;\underline{p}rotein\;\underline{A}$) gene was cloned into pBP244, resulting in pBP438. S. typhimurium harboring pBP438 grown until the stationary phase, secreted a higher level of PspA into the culture supernatants than did the strain harboring pYA3494. The strain harboring pBP438 secreted a supernatant amount 1.71-fold, a periplasmic space amount 1.47-fold, and an outer membrane amount 1.49-fold higher than that of pYA3494. S. typhimurium ${\chi}8554$ kept the $Asd^+$ plasmid pBP244 and pBP438 for 60 generations in LB broth harboring DAP, thereby indicating that pBP244 and pBP438 were quite stable in the Salmonella strain.

• Journal of Astronomy and Space Sciences
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• v.18 no.3
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• pp.249-256
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• 2001

KARI(Ko.ea Aerospace Research Institute) has measured the ionospheric electron temperature and density over the Korean Peninsular with the Langmuir and Electron Probe(LEP) onboard the Korean Sounding Rocket-II(KSR-II) In 1998. The purpose of LEP is to measure the electron density and temperature profile in the ionosphere. LEP consists of the Langmuir probe(LP) and the Electron temperature Probe(ETP) which are widely used for the measurement of the ionospheric plazma environment . We discuss the development of the Langmuir and Electron Probe which will be onboard the KSR-III and some test results in a simulated space plasma environment with the plasma chamber at the ISAS in Japan. These measurements could contribute to the basic study of ionospheric environment which also can be compared with other reference models such as IRI and PIM.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.9
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• pp.4281-4288
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• 2016

Background: Traditional meta-analyses or systematic reviews of randomized controlled trials (RCTs) have been used to compare laser surgeries and transurethral resection of the prostate (TURP) for benign prostate hyperplasia (BHP), but they cannot provide a hierarchy regarding efficacy and safety of treatment. Objective: We therefore performed a network meta-analysis (NMA) to compare and create hierarchies for efficacy and safety of TUPR and laser surgeries for BPH. Materials and Methods: We searched for reports of RCTs published up to April 25, 2015. After methodological quality assessment and data extraction, we performed an NMA to compare TURP and laser surgeries for BPH. Results: We ranked the treatments of TURP and laser surgeries for BPH. For IPSS at 6 months, holmium laser resection of the prostate (HoLRP) ranked the first-best and at 12 months, holmium laser enucleation of the prostate (HoLEP). For Qmax at 6 and 12 months, HoLEP ranked the first-best; for operative time it was TURP; for cathedral removal time, diode laser enucleation of the prostate (DiLEP) ranked the first-best. Conclusions: Although TURP is considered the gold standard for treating BPH, it is not better in terms of efficacy and safety compared with the laser surgery. Our NMA created hierarchies for the 9 types of surgery in terms of efficacy and safety, which should help clinicians choose the best approach for the individual patient.

• The Journal of Korean Society for Radiation Therapy
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• v.25 no.1
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• pp.1-8
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• 2013

Purpose: A selection of proper energy in treatment planning is very important because of having different dose distribution in body as photon energy. In generally, the low energy photon has been used in intensity-modulated radiation therapy (IMRT) for head and neck (H&N) cancer. The aim of this study was to evaluate the effect of partially used high energy photon at posterior oblique fields on IMRT plan for H&N cancer. Materials and Methods: The study was carried out on 10 patients (nasopharyngeal cancer 5, tonsilar cancer 5) treated with IMRT in Seoul National University Bundang Hospital. CT images were acquired 3 mm of thickness in the same condition and the treatment plan was performed by Eclipse (Ver.7.1, Varian, Palo Alto, USA). Two plans were generated under same planing objectives, dose volume constraints, and eight fields setting: (1) The low energy plan (LEP) created using 6 MV beam alone, (2) the partially used high energy plan (PHEP) created partially using 15 MV beam at two posterior oblique fields with deeper penetration depths, while 6 MV beam was used at the rest of fields. The plans for LEP and PHEP were compared in terms of coverage, conformity index (CI) and homogeneity index (HI) for planning target volume (PTV). For organs at risk (OARs), $D_{mean}$ and $D_{50%}$ were analyzed on both parotid glands and $D_{max}$, $D_{1%}$ for spinal cord were analyzed. Integral dose (ID) and total monitor unit (MU) were compared as addition parameters. For the comparing dose to normal tissue of posterior neck, the posterior-normal tissue volume (P-NTV) was set on the patients respectively. The $D_{mean}$, $V_{20Gy}$ and $V_{25Gy}$ for P-NTV were evaluated by using dose volume histogram (DVH). Results: The dose distributions were similar with regard to coverage, CI and HI for PTV between the LEP and PHEP. No evident difference was observed in the spinal cord. However, the $D_{mean}$, $D_{50%}$ for both parotid gland were slightly reduced by 0.6%, 0.7% in PHEP. The ID was reduced by 1.1% in PHEP, and total MU for PHEP was 1.8% lower than that for LEP. In the P-NTV, the $D_{mean}$, $V_{20Gy}$ and $V_{25Gy}$ of the PHEP were 1.6%, 1.8% and 2.9% lower than those of LEP. Conclusion: Dose to some OARs and a normal tissue, total monitor unit were reduced in IMRT plan with partially used high energy photon. Although these reduction are unclear how have a clinical benefit to patient, application of the partially used high energy photon could improve the overall plan quality of IMRT for head and neck cancer.