• Title/Summary/Keyword: Lep

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Analysis of Single Nucleotide Polymorphisms of Leptin Gene in Hanwoo(Korean Cattle) (한우 Leptin 유전자의 단일 염기 다형성 분석)

  • Lee, J.-Min;Song, G.C.;Lee, J.Y.;Kim, Young-Bong
    • Journal of Animal Science and Technology
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    • v.49 no.3
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    • pp.295-302
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    • 2007
  • Leptin, the product of the obese(ob) gene, is an adipocyte-derived hormone for the regulation of whole- body energy storage and energy usage. It has been reported that the homozygous mutations in the gene for leptin(LEP) induce obesity and reduce energy expenditure. In cattle, LEP has significant roles directly or indirectly related with phenotypes such as body weight and fat deposits, therefore SNPs of LEP have been considered important genetic marker to estimate carcass fat content in cattle. In this study, SNPs were screened in LEP(2,222 bp) between intron 1 to 3'-UTR from 24 independent Hanwoo(Korean cattle) by PCR and DNA sequencing. Total 25 SNPs were found and two nonsynonymous SNPs including T1163A(V19E) and G3256A(G132D) were newly detected only from Hanwoo. Among 20 SNPs previously reported in cattle, 16 SNPs were found in Hanwoo; however, the frequencies of some SNPs were significantly different between Hanwoo and western cattle breeds. The other 4 SNPs were not detected from Hanwoo. These Hanwoo specific SNP patterns in LEP will be used in development of molecular marker and application to genetic improvement of Hanwoo.

Experimental determination of liquid entry pressure (LEP) in vacuum membrane distillation for oily wastewaters

  • Racz, Gabor;Kerker, Steffen;Schmitz, Oliver;Schnabel, Benjamin;Kovacs, Zoltan;Vatai, Gyula;Ebrahimi, Mehrdad;Czermak, Peter
    • Membrane and Water Treatment
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    • v.6 no.3
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    • pp.237-249
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    • 2015
  • In this study we investigate a laboratory scale vacuum membrane distillation system to produce pure water from model oil in water emulsion. Experimental determination of liquid entry pressure (LEP) of a commercial Durapore$^{TM}$ GVPH flat sheet membrane using model emulsions in various oil concentrations has been carried out. Two different methods of liquid entry pressure determination - a frequently used, so-called static and a novel dynamic method - have been investigated. In case of static method, LEP value was found to be 2.3 bar. No significant effect of oil content on LEP was detected up to 3200 ppm. In contrast, LEP values determined with dynamic method showed strong dependence on the oil concentration of the feed and decreased from 2.0 bar to a spontaneous wetting at 0.2 bar in the range 0-250 ppm, respectively. Vacuum membrane distillation tests were also performed. The separation performance is evaluated in terms of flux behavior, total organic carbon removal and droplet size distribution of the feed and final retentate. No significant effect of oil content on the flux was found ($5.05{\pm}0.31kgm^{-2}h^{-1}$) up to 250 ppm, where a spontaneous wetting occurred. High separation performance was achieved along with the increasing oil concentration between 93.4-97.0%.

Performance and the Current Reform Process of Regional Development Agencies in England (영국 지역발전기구의 활동 성과와 구조재편 동향)

  • Lee, Jong-Ho
    • Journal of the Economic Geographical Society of Korea
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    • v.14 no.4
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    • pp.553-567
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    • 2011
  • Since their establishment in 1999, Regional Development Agencies in England have been a critical catalyst for sustaining regional development, by linking the central government and the region. Nevertheless, the new Coalition Government formed in May 2010 is to abolish RDAs and is to be replaced by Local Enterprise Partnerships(LEP). This article looks at the performance and the present reform process of the English Regional Development Agencies(RDA). It argues that RDAs have been a sort of laboratory to expose the possibility of realizing the new regionalist approach away from the government-centered approach. Nevertheless, the case of RDAs in England shows that the RDA model is less likely to be effective without substantial devolution. It shows that the extent to which RDAs contribute to the regional economy tends to be much higher in soft infra-centered projects, such as business supports and skills development, than physical infrastructure projects. It argues that the LEP model, which is to replace RDAs, is controversial, especially in terms of spatial boundary and financial structure.

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Studies on the Insect Fauna of Mt. Gyeryong(I) (계룡산(鷄龍山)의 곤충상(昆蟲相)에 관(關)한 조사연구(調査硏究)(제(第)I보(報)))

  • Chang, Young Duck;Choe, Kwang Ryul
    • Korean Journal of Agricultural Science
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    • v.9 no.2
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    • pp.519-539
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    • 1982
  • An preliminary study was made with special references on the insect fauna of Mt. Gyeryong during the period from mid-May to mid-September 1981. The results were obtained as follows; 1. 673 species of insects within 156 families of 20 orders were identified and listed herewith. 2. The 16 species are first records from Korea : Phaneraptera nigro-antennata (Tettigoniidae : Orthop.), Phraraortes kumamotoensis(Phasmidae : Phasm.), Nesogaster lewisi (Nesogasteridae : Dermap), Polymerus palustris(Miridae : Hemip.), Agrosteomela indica (Chrysomelidae:Col.), Monochimus sparsutus (Cermbicidae : Col.), Oberthiiria ialcigera (Bombycidae: Lep.), Alcis albiiera (Geometridae : Lep.), Proplepsis diazama (G eometridae : Lep.) Pandemis cinnamomeana (Tortricidae : Lep.), Hypenodes squalida (Noctuidae : Lep.), Hypolimnas bolina (Nymphalidae : Lep.), Ctenophora nohirae (Tipulidae: Dip.), Ortalotrypeta isshiki (Trypetidaedae : Dip.), Trypeta artemisicola (Trypetidae : Dip.), Ichneumom 8-guttatus ( Ichneumonidae : Hymenop.). 3. We could find a considerable number of Oriental fauna species, Lepismachilis nipponica, Nezara antennata, Parapolybia varia, Anthophora zonata, Parnara guttata, Byasa alcinous, Eurema laeta, Pieris canidia, Eizera maha, Kaniska canace, Danaus sita including two newly recorded species, Monochimus sparstus and Hypolimnas bolina.

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Association of leptin, toll-like receptor 4, and chemokine receptor of interleukin 8 C-X-C motif single nucleotide polymorphisms with fertility traits in Czech Fleckvieh cattle

  • Jecminkova, Katerina;Muller, Uwe;Kyselova, Jitka;Sztankoova, Zuzana;Zavadilova, Ludmila;Stipkova, Miloslava;Majzlik, Ivan
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.11
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    • pp.1721-1728
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    • 2018
  • Objective: The use of genetic markers can help to enhance reproduction in cattle, which is a very important trait for profitability in dairy production systems. This study evaluated the association between genotypes of leptin (LEP), toll-like receptor 4 (TLR4), and chemokine receptor of interleukin 8 C-X-C motif (CXCR1) genes and fertility traits in Czech Fleckvieh cattle. Methods: Phenotypic data from 786 Czech Fleckvieh cows raised on 5 farms in the Czech Republic were used, along with information from the 1st three parities. To determine genotype, the polymerase chain reaction-restriction fragment length polymorphism method was used. Results: Except for LEP g.-963C>T, all studied genotype frequencies of single nucleotide polymorphisms (SNPs) were distributed according to the Hardy-Weinberg equilibrium. Two LEP SNPs (g.-963C>T and c.357C>T) were associated with the age at the 1st calving, days open (DO), pregnancy rate after 1st service (PR), and calving interval (CLI). In LEP g.-963C>T the TT genotype heifers firstly calved 24 days earlier than CC genotype and the CT genotype cow showed a tendency for shorter DO and higher PR. In LEP c.357C>T we observed longer CLI and DO period in TT cows. In general, we can propose the TT genotype of g.-963C>T as favorable and the TT genotype of c.357C>T as unfavorable for a cow's fertility. Heterozygotes in TLR4 c.-226C>G were significantly associated with shorter CLI, and presented a nonsignificant tendency to be associated with higher PR. In CXCR1 c.777 C>G, we did not observe any relationship of this SNP with reproduction. Conclusion: Overall, the results showed that LEP could be an effective marker for improving reproduction in Czech Fleckvieh cattle. This study also provides novel insights into the relationship between TLR4 and CXCR1 SNPs and reproduction in dual-purpose cattle.

Affecting the Characteristic Variables(System, Information) of Computing Tax Accounting Systems and Personal Variables to Educational Performance - Focused on KcLep Software - (전산세무회계시스템의 특성변수(시스템, 정보)와 개인변수가 교육성과에 미치는 영향 - KcLep을 중심으로 -)

  • Kim, Hyeon-Gyu;So, Won-Geun;Kim, Ha-Kyun
    • Management & Information Systems Review
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    • v.34 no.5
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    • pp.111-125
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    • 2015
  • The article starts with a review of system characteristic, information characteristic and personal characteristic on educational performance through educational satisfaction. This survey is intended for educatee's who take the course of KcLep. We found that all variables of system characteristic(easiness, flexibility and reliability) significantly effect the educational satisfaction. Information characteristic(timeliness, usefulness) significantly effect on educational satisfaction, but the correctness doesn't significantly effect on educational satisfaction. Personal characteristic(self-efficacy and achievement motivation) significantly effect on educational satisfaction, but the computing ability doesn't significantly effect on educational satisfaction. We found that the educational satisfaction significantly effect on the education performance.

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Effect of Electrode Placement on Procaine Iontophoresis (전극배치가 Procaine 이온도입에 미치는 영향)

  • Lee, Jae-Hyoung;Song, In-Young;Kook, Jee-Youn
    • Journal of Korean Physical Therapy Science
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    • v.4 no.2
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    • pp.399-403
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    • 1997
  • The purpose of this study was to determine the efficacy of electrode placement on procaine iontophoresis. Thirty-three healthy students with an age range of 19 to 34 years, were participated in this study. The subjects were randomly assigned into 3 groups. Each subjects received iontophoresis on the proximal 1/3 of volar surface of dominant forearm with soft cotton pad($3.5{\times}3.5cm$) soaked in 2 ml of 4% procaine hydrochloride (pH 5.1) at 4 mA for 10 minutes(total current 40 mA min) of anodal DC. In transversal electrode placement(TEP) group, dispersive electrode was placed on the proximal 1/3 of dorsal surface of the forearm. In longitudinal electrode placement (LEP) group and control group, dispersive electrode were placed on the distal 1/3 of volar surface of the forearm. After procaine iontophoresis, duration of anesthesia were evaluated at five minutes intervals on five random locations in the iontophoretically area using a 21-gauge sterile hypodermic needle pressed with 1 mm invagination until return the sharp pin-pricking pain sensation. The data were ana lysed with one-way ANOVA to determine signific~nt differences between groups. The results showed significantly differences in the local anesthetic duration between the 3 groups(p<0.001). The anesthetic durations of TEP group and LEP group were significantly longer when compared with control group(p<0.05). Anesthetic durations of TEP group and LEP group were not significantly difference, but anesthetic duration of LEP group tends to longer than TEP group. In view of these results, clinicians should consider the electrode placement method when performing the iontophoresis.

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Accuracy Investigation of RPC-based Block Adjustment Using High Resolution Satellite Images GeoEye-1 and WorldView-2 (고해상도 위성영상 GeoEye-1과 WorldView-2의 RPC 블록조정모델 정확도 분석)

  • Choi, Sun-Yong;Kang, Jun-Mook
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.30 no.2
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    • pp.107-116
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    • 2012
  • We investigated the accuracy in three dimensional geo-positioning derived by four high resolution satellite images acquired by two different sensors using the vendor-provided rational polynomial coefficients(RPC) based block adjustment in this research. We used two in-track stereo pairs of GeoEye-1 and WorldView-2 satellite and DGPS surveying data. In this experiment, we analyzed accuracies of RPC block adjustment models of two kinds of homogeneous stereo pairs, four kinds of heterogeneous stereo pairs, three 3 triplet image pairs, and one quadruplet image pair separately. The result shows that the accuracies of the models are nearly same. The accuracy without any GCPs reaches about CEP(90) 2.3m and LEP(90) 2.5m and the accuracy with single GCP is about CEP(90) 0.3m and LEP(90) 0.5m.

Multi-head Inkjet Patterning System for Manufacturing a Full Color Polymer Light Emitting Device (pLED) (고분자 유기 EL 제조를 위한 멀티헤드형 잉크젯 패터닝 시스템)

  • Oh, Je-Hoon;Kim, Si-Kyoung;Yoon, Hee-Youl;Oh, Se-Il;Kang, Yoo-Myung;Kim, Kwang-Il
    • Proceedings of the KSME Conference
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    • 2003.04a
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    • pp.1219-1225
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    • 2003
  • According to the increase of lifetime and efficiency, the interest in the pLED has dramatically increased recently because pLED can be applied to large-size and flexible displays. The core process in the manufacture of pLED is the printing process of red, green and blue light emitting polymers (LEP), and inkjet printing method is one of the promising technology to print red, green and blue LEP on glass substrates. In this work, we developed a multi-head inkjet patterning system with 3 heads for each color. The developed inkjet patterning system is composed of the precise positioning system, head controller circuit, real-time ink drop evaluation system, maintenance system, and stable ink supply system. Finally, we investigated the stability and reliability of the system by printing red, green and blue LEP on the dummy substrate.

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KSR-III 과학탑재 시스템 개발

  • Hwang, Seung-Hyun;Kim, Jhoon;Chun, Young-Doo;Kim, Yong-Ha;Jang, Min-Hwan
    • Aerospace Engineering and Technology
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    • v.1 no.2
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    • pp.83-90
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    • 2002
  • This paper describes the development of scientific payload system onboard the KSR-III. The ozone detector(UVR), Langmuir electron probe(LEP), airglow photometer(AGP), and magnetometer(MAG) constitute this system. The purpose of the ozone detector is to measure the ozone density profile and the LEP measures the electron density and temperature in the ionosphere over the Korean Peninsula. The AGP detects airglow in the mesosphere over the Korean Peninsular. The MAG provides rocket attitude and the magnetic fluctuation information during the flight. With the developed payloads, the ground calibration tests and the environmental tests have been performed.

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