• Title/Summary/Keyword: LeeWhang

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Differentiation of Roots of Glycyrrhiza Species by 1H Nuclear Magnetic Resonance Spectroscopy and Multivariate Statistical Analysis

  • Yang, Seung-Ok;Hyun, Sun-Hee;Kim, So-Hyun;Kim, Hee-Su;Lee, Jae-Hwi;Whang, Wan-Kyun;Lee, Min-Won;Choi, Hyung-Kyoon
    • Bulletin of the Korean Chemical Society
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    • v.31 no.4
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    • pp.825-828
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    • 2010
  • To classify Glycyrrhiza species, samples of different species were analyzed by $^1H$ NMR-based metabolomics technique. Partial least squares discriminant analysis (PLS-DA) was used as the multivariate statistical analysis of the 1H NMR data sets. There was a clear separation between various Glycyrrhiza species in the PLS-DA derived score plots. The PLS-DA model was validated, and the key metabolites contributing to the separation in the score plots of various Glycyrrhiza species were lactic acid, alanine, arginine, proline, malic acid, asparagine, choline, glycine, glucose, sucrose, 4-hydroxy-phenylacetic acid, and formic acid. The compounds present at relatively high levels were glucose, and 4-hydroxyphenylacetic acid in G. glabra; lactic acid, alanine, and proline in G. inflata; and arginine, malic acid, and sucrose in G. uralensis. This is the first study to perform the global metabolomic profiling and differentiation of Glycyrrhiza species using $^1H$ NMR and multivariate statistical analysis.

Substituent Effects on the Gas-Phase Pyrolyses of 2-Substituted Ethyl N,N-Dialkylcarbamates: A Theoretical Study

  • Kim, Chang-Kon;Kim, Dong-Jin;Zhang, Hui;Hsieh, Yih-huang;Lee, Bon-Su;Lee, Hai-Whang;Kim, Chan-Kyung
    • Bulletin of the Korean Chemical Society
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    • v.28 no.6
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    • pp.1031-1034
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    • 2007
  • The R- and Z-substituent effects for the gas-phase thermal decompositions of carbamates, R2NC(=O)- OCH2CH2Z, have been investigated theoretically at B3LYP level with 6-31G(d) and 6-31++G(d,p) basis sets. Both the Z- and R-substituent effects on reactivity (ΔH≠) were well consistent with experimental results, although the R-substituent effect was underestimated theoretically. No correlations were found between activation enthalpies and reaction enthalpies. The substituent effects on reactivity seemed to be complicated at a glance, but were understandable by concurrent electronic and steric factors. Variations of bond lengths at TS structures were well correlated with the Taft's σ* values and the TS structures became tighter as the Zsubstituent became a stronger electron-acceptor (δσ* > 0). However the effects of R-substituents on the TS structures were much smaller when compared to those of Z-substituents.

A Case of Lung Injury Caused by Ammonia-Gas Inhalation (암모니아 가스 흡입에 의한 폐 합병증 1예)

  • Lee, Jong-Deog;Sin, Won-Ho;Kim, Kuen-Yong;Lee, Won-Ju;Choi, Jin-Hak;Whang, Young-Sil
    • Tuberculosis and Respiratory Diseases
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    • v.38 no.1
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    • pp.70-73
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    • 1991
  • We have experienced a case of lung injury caused by accidental inhalation of ammonia gas in a 34 year-old-man. By the explosion of ammonia tank in a refrigerator boat he inhaled ammonia gas. Several minutes later, he suffered from severe dyspnea and visual loss. On arrival at emergency room, analysis of arterial blood gas revealed severe hypoxemia and his chest film showed bilateral pulmonary infiltrates. Under the impression of adult respiratory distress syndrome, mechanical ventilator was applied to the patient. After recovery from ARDS and tracheal edema, he complained of some hemoptysis and productive sputum during the admission. So we checked bronchoscopy and bronchograpy which showed tracheal bullae just above carina and tubular bronchiectatic change in the right lower lobe. We report a case of lung injuries-ARDS, tracheal bullae, and bronchiectasis-caused by inhalation of ammonia gas with the review of the relevant literatures.

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Studies on Preparation of Resion-Metal Chelates and Its Catalytic Activity for the Oxidation of Hydroxy Compounds and l-Ascorbic Acid (Resin-Metal Chelate의 제조와 Hydroxy화합물 및 l-Ascorbic Acid의 산화 촉매효과에 관한 연구)

  • Whang Kyu-Ja;Lee Young Sun;Kim Young Mi;Lee Yong-Keun
    • Journal of the Korean Chemical Society
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    • v.33 no.1
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    • pp.113-119
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    • 1989
  • Chelating resins containing hydrazide or triethylenetetramine side chain were prepared using a commercial cation exchage resin, Diaion WK 11, and their nitrogen contents were determined by elemental analysis. The synthesized resin, and commercial chelating resins, (Diaion-CR 10 and-CR 20) were treated with various metal chelates of which metal contents were subsequently determined by chelatometry. Sectioned beads of the resin-metal chelates were also observed using electron microprobs X-ray analyzer. To examine the catalytic activity of the resin-metal chelates, they were applied to the oxidation of various hydroxy compounds and l-ascorbic acid, and found to be effective catalysts.

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A Study on C-axis Preferred Orientation of ZnO Thin Film at Ar/$O_2$gas ratios (Ar/$O_2$에 따른 ZnO 박막의 C-축 배향성에 관한 연구)

  • Lee, Dong-Yoon;Park, Yong-Wook;Nam, Sahn;Lee, Jeon-Kook;Kim, Hyun-Jai;Yoon, Seok-Jin;Whang, Keum-Chan
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.13 no.7
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    • pp.617-624
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    • 2000
  • Zinc Oxide(ZnO) thin films on Si(100) substrate were deposited by RF magnetron reactive sputtering. The charcteristics of ZnO thin films on argon/oxygen(Ar/O$_2$)gas ratios RF power and substrate temperature were investigated by XRD, SEM, and AFM analyses. C-axis preferred orientation resistivity and surface roughness highly depended on Ar/O$_2$gas ratios. The resistivity of ZnO thin films rapidly increased with increasing oxygen ratio and the resistivity value of 9$\times$10$^{7}$ $\Omega$cm was obtained at a working pressure of 10 mTorr with Ar/O$_2$=50/50. The surface roughness was also improved with increasing oxygen ratio and the ZnO films deposited with Ar/O$_2$=50/50 showed the excellent roughness value of 28.7$\AA$.

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Pinhole Phenomena of Dielectric Breakdown in External Electrode Fluorescent Lamps (외부전극 형광램프의 절연 파괴에 의한 핀홀(Pinhole) 현상)

  • Lee, J.;Kim, S.;Song, H.;Gill, D.;Lee, D.;Koo, J.;Cho, G.;Cho, M.;Whang, M.;Kim, Y.
    • Proceedings of the KIEE Conference
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    • 2004.11a
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    • pp.29-32
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    • 2004
  • 외부전극 형광램프의 구동에서 과도한 전력을 인가하면, 치부전극 부분의 유리관 표면에 작은 원형의 구멍이 발생하여 램프가 파손된다. 이를 핀홀이라고 지칭한다. 핀홀은 치부전극과 유리관을 유전층으로 하는 캐패시터의 절연파괴로 분석된다. 치부전극에 정상 동작이상의 고 전압을 인가하면, 고 전류에 의하여 전극부분에 상당한 열이 발생하고, 이러한 전극부분에 발생하는 열과 고 전압에 의한 유리층 자제의 강한 전기장에 의하여 절연이 파괴되면서 핀홀이 발생한다. 이러한 현상은 유리판을 절연층으로 하여 유리판 양면에 전극을 형성하여 고 전압에 의한 절연 파괴 실험과 동일한 현상으로 이해된다.

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Clinical Evaluation of Patients with Atrophied Left Lobe on the Liver Scan (간 스캔에서 나타난 간 좌엽위축의 임상적 의의)

  • Chung, Jin-Hong;Chung, Byung-Chun;Kim, Kwang-Won;Sohn, Sang-Kyun;Lee, Jae-Tae;Lee, Kyu-Bo;Whang, Kee-Suk
    • The Korean Journal of Nuclear Medicine
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    • v.24 no.1
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    • pp.56-61
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    • 1990
  • We evaluated 85 cases with atrophy of left lobe among 11,133 cases performed liver scan using $^{99m}Tc-phytate$ from January 1984 to January 1990 at Kyungpook National University Hospital in association with underlying causes and related conditions. Seventeen cases seemed to be due to biliary tract diseases, eg, cholelithiasis, cholangiocarcinoma, clonorchiasis and postcholecystectomy state. Fifteen cases were patients with primary and metastatic hepatic malignancies. One case had a history of hepatic irradiation. Thirty cases comprised acute hepatitis, chronic hepatitis, liver cirrhosis and fatty liver. However no causative abnormalities could be detected in 22 cases despite of meticulous diagnostic work-up.

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A study about Views of the Great Learning(大學) of the Three Countries in East Asia at 17th Century (17세기(世紀) 동(東)아시아 3국(國)의 『대학(大學)』관(觀) 고찰(考察))

  • Lee, Yongsoo
    • (The)Study of the Eastern Classic
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    • no.36
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    • pp.265-299
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    • 2009
  • The Great Learning is an essential scripture of Confucianism that has had great influence on the politics, thoughts, society and culture of the East Asia which contains Korea, Japan and China. In case of Japan, the doctrine of Toegye(退溪) is flown into pre-Tokugawa era, and as the doctrine of Zhu Xi(朱熹) exercise influences over the other thoughts, the importance of the Great Learning is embossed relatively in Tokugawa era. The characteristic of Japanese confucianism of Tokugawa era is to lay weight on real world as such, and the Japanese confucianism has grown up academically centers on exhaustive reinterpretation about some Confucian classics. And Backho-Yoon Hyu(白湖 尹?), Seokye-Park Sedang(西溪 朴世堂) who lived in 17th century of Joseon dynasty attempt new interpretation about the Great Learning and they have an objection to the explanatory notes of Zhu Xi. In the same period of China, there are similar academic trends around Whang Jong Hi(黃宗羲), Ko Yeom Mu(顧炎武), Wang Fu Chi(王夫之). In other words, new views of real scholarship which reject emptiness and put much value on reality were current of thoughts that have been common to the oriental three countries in early and middle 17th century. The main object of this paper is to understand the attitude and understanding about the Confucian classics especially the Great Learning of the scholars who lived in early and middle Tokugawa era. It will be a decisive clue to understand the ninucture of thoughts system of them. Through these work, we understand how it has had influenced to thinking-ninucture and lives of the Japanese. And the other purpose of this paper is to understand characteristics of them when we compare that vking-ninucture and lives of the Japanese Confuciang-ninearly and middle Tokugawa era with in the same period of Jeseon and the later Ming(明) and early Ching(淸) dynasty.

Query Expansion Using Augmented Terms in an Extended Boolean Model

  • Nguyen, Tuan-Quang;Heo, Jun-Seok;Lee, Jung-Hoon;Kim, Yi-Reun;Whang, Kyu-Young
    • Journal of Computing Science and Engineering
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    • v.2 no.1
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    • pp.26-43
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    • 2008
  • We propose a new query expansion method in the extended Boolean model that improves precision without degrading recall. For improving precision, our method promotes the ranks of documents having more query terms since users typically prefer such documents. The proposed method consists of the following three steps: (1) expanding the query by adding new terms related to each term of the query, (2) further expanding the query by adding augmented terms, which are conjunctions of the terms, (3) assigning a weight on each term so that augmented terms have higher weights than the other terms. We conduct extensive experiments to show the effectiveness of the proposed method. The experimental results show that the proposed method improves precision by up to 102% for the TREC-6 data compared with the existing query expansion method using a thesaurus proposed by Kwon et al.

A Study on Application of Gypsum Main Blended Prescription From Dongeuibogam (동의보감(東醫寶鑑) 중 석고(石膏)가 주약(主藥)으로 배오(配伍)된 방제(方劑)의 활용(活用)에 대한 고찰(考察))

  • Oh, Whang;Lee, Jang-Cheon
    • Herbal Formula Science
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    • v.15 no.1
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    • pp.1-19
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    • 2007
  • This study was investigated to make sure the range of Gypsum treatment, the nature of disease, the pathology and the dosage of it in Dongeuybogam. The following conclusions were reached through investigations on the prescriptions that use Gypsum as a key ingredient. The Gypsum blended prescriptions are utilized in 23 fields of treatment such as cold, head. ect. Prescriptions that use Gypsum as the main ingredient are used commonly in the treatment of cold, head disease, fever, skin disease, diabetes, stroke, ophthalmic disease, jaundice, ENT disease and dental disease. The Gypsum is used for nature of disease which of cold, heat(fever), summer heat, phlegm, malfunction of liver, malfunction of liver and kidney, heat of stomach, malfunction of spleen and fever of stomach. The clinical dosage of Gypsum has ranged at a wide variety of amount from 1.6g to 16g per dose with 4g ${\sim}$ 8g being the typical dose for most treatment. The Gypsum is applied as a fundamental prescription with several herb remedies for the pathology.

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