• Title/Summary/Keyword: Lee Ji-Ham

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The Impact of Different Endotracheal Suction Methods on Respiratory Function: Normal Saline with Chest Vibration vs Normal Saline with Expectorant Mixture (기관내 흡인방법에 따른 호흡기능의 차이)

  • Cho, Hyo-Im;Lee, Young-Whee;Ham, Ok-Kyung;Lim, Ji-Young
    • Korean Journal of Adult Nursing
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    • v.20 no.2
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    • pp.209-218
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    • 2008
  • Purpose: Regarding the respiratory function of patients with an artificial airway, this study compared the effects between normal saline with chest vibration and normal saline with expectorant mixture, administered before endotracheal suction. Methods: The study was conducted in the ICUs of one university hospital located in Incheon. The experimental group I received normal saline with chest vibration administered before endotracheal suction while the experimental group II received normal saline with expectorant mixture administered before endotracheal suction. For respiratory function, $PaO_2$, $PaCO_2$, and $O_2$ saturation were measured by ABGA at 3 minutes after endotracheal suction for both pre-test and post-test. Results: The two groups were not different significantly regarding $PaO_2$ level and $O_2$ saturation after the treatments, while, the experimental group II had lower $PaCO_2$ level than the experimental group I after the treatments (t = 2.075, p = .042). For experimental group II, post-test score of $PaCO_2$ level was significantly lower than that of the pre-test score (t = 1.842, p = .075). Conclusion: The administration of normal saline with expectorant mixture before endotracheal suction reduced $PaCO_2$ level and improved the respiratory function.

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The Comparison of the Neurocognitive Functions between Dysthymic Disorder and Major Depressive Disorder (기분부전장애 환자군과 주요우울장애 환자군의 신경인지학적 기능 비교)

  • Kang, Rhee-Hun;Ham, Byung-Joo;Cha, Ji-Hyun;Lee, Min-Soo
    • Korean Journal of Biological Psychiatry
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    • v.9 no.2
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    • pp.103-111
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    • 2002
  • Neurocognitive research focusing on cognitive deficits in Depression has resulted in several important but yet potentially contradictory findings. Much literature documents the presence of significant neurocognitive impairments in depressive patients. Studies have shown that dysthymic disorder patients demonstrate a diffuse pattern of cognitive impairment which is frequently indistinguishable from that of focal braindamaged patients. Some reports have suggested that there is a focal pattern of deficit, such as anterior cingulate dysfunction, frontal lobe impairment, or dysfunction of the temporal-limbic cortex. The aim of this study is to evaluate the neurocognitive functions in dysthymic disorder patients, and to compare the functions with those of major depressive disorder patients. The subjects are 17 dysthymic disorder patients. And their neurocognitive functions are compared with those of 23 major depressive episode patients. Patients with a history of neurologic disease, alcohol dependence, substance abuse and mental retardation are excluded. They are assessed with a part of Vienna Test System which is computerized neurocognitive function tests and can evaluate attention, eductive ability, reproductive ability, visuoperceptual analysis, vigilance, visual immediate memory, the speed of information-processing, judgement, and fine motor coordinations. There are no other specific difference between two groups, except the result of cognitrone test. This study provides information about the neurocognitive functions and some difference between major depressive disorder patients and carefully diagnosed dysthymic disorder patients.

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A Study on Isotopic Fractionation between Ice and Meltwater by a Melting Experiment (융해실험에 의한 얼음과 융해수의 안정동위원소분화에 관한 연구)

  • Lee, Jeonghoon;Ham, Ji-Young;Hur, Soon Do
    • Ocean and Polar Research
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    • v.37 no.4
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    • pp.327-332
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    • 2015
  • Isotopic compositions of ice and meltwater play a very crucial role in paleoclimate studies based on ice cores and water resources research conducted in alpine hydrogeology. Better understanding of variations in the stable isotopic compositions of water is required since changes from ice to liquid water are gaining more attention due to recent climate change. In this work, a melting experiment was designed and conducted to investigate how the isotopic compositions of ice vary with time by heat sources, such as solar radiation. We conducted the melting experiment for 22 hours. The discharge rate rose to a maximum value after 258 minutes and gradually declined because we fixed the heat source. The isotopic compositions of meltwater increased linearly or to a second degree polynomial. The linear relationship between oxygen and hydrogen has a slope of 6.8, which is less than that of the Global Meteoric Water Line (8) and higher than a theoretical value (6.3). The deuterium excess decreased when ${\delta}D$ or ${\delta}^{18}O$ increases or vise versa since the slope of the relationship for ice-liquid exchange is less than 8. These findings and the apparatus of the melting experiments will make a helpful contribution to the studies of stable isotopes and the melting process in temperate and polar regions.

Microstructural and Wear Properties of WC-based and Cr3C2-based Cermet Coating Materials Manufactured with High Velocity Oxygen Fuel Process (고속 화염 용사 공정으로 제조된 WC계 및 Cr3C2계 Cermet 코팅 소재의 미세조직 및 마모 특성)

  • Kang, Yeon-Ji;Ham, Gi-Su;Kim, Hyung-Jun;Yoon, Sang-Hoon;Lee, Kee-Ahn
    • Journal of Powder Materials
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    • v.25 no.5
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    • pp.408-414
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    • 2018
  • This study investigates the microstructure and wear properties of cermet (ceramic + metal) coating materials manufactured using high velocity oxygen fuel (HVOF) process. Three types of HVOF coating layers are formed by depositing WC-12Co, WC-20Cr-7Ni, and Cr3C2-20NiCr (wt.%) powders on S45C steel substrate. The porosities of the coating layers are $1{\pm}0.5%$ for all three specimens. Microstructural analysis confirms the formation of second carbide phases of $W_2C$, $Co_6W_6C$, and $Cr_7C_3$ owing to decarburizing of WC phases on WC-based coating layers. In the case of WC-12Co coating, which has a high ratio of $W_2C$ phase with high brittleness, the interface property between the carbide and the metal binder slightly decreases. In the $Cr_3C_2-20CrNi$ coating layer, decarburizing almost does not occur, but fine cavities exist between the splats. The wear loss occurs in the descending order of $Cr_3C_2-20NiCr$, WC-12Co, and WC-20Cr-7Ni, where WC-20Cr-7Ni achieves the highest wear resistance property. It can be inferred that the ratio of the carbide and the binding properties between carbide-binder and binder-binder in a cermet coating material manufactured with HVOF as the primary factors determine the wear properties of the cermet coating material.

Activity of Crude Extract of Rubus crataegifolius Roots as a Potent Apoptosis Inducer and DNA Topoisomerase I Inhibitor

  • Lee, Ji-Hyeon;Ham, Yoon-Ah;Choi, Sang-Ho;Im, Eun-Ok;Jung, Jee-H;Im, Kwang-Sik;Kim, Dong-Kyoo;Ying-Xu;Wang, Min-Wei;Kim, Nam-Deuk
    • Archives of Pharmacal Research
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    • v.23 no.4
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    • pp.338-343
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    • 2000
  • The effects of methanol extract of Rubus crategifolius roots and its solvent fractions were investigated on the proliferation of MCF-7 human breast carcinoma cells. The methanol extract inhibited the proliferation of MCF-7 cells in a concentration dependent manner. Moreover, their methanol soluble (W-M) fraction had the greatest inhibitory effect on the growth of MCF-7 cells. To evaluate whether the W-M fraction affects on the cell cycle of MCF-7 cells, cells treated with this fraction were analyzed with flow cytometry. The W-M fraction increased $G_0$/$G_1$phase after 24 h-treatment and induced apoptosis after 48 h-treatment. The hallmark of apoptosis, DNA fragmentation, also appeared by W-M fraction after 48 h-treatment. Furthermore, the methanol extract and its W-M fraction inhibited the activity of the topoisomerase 1 enzyme in the relaxation assay, From these results, their W-M fraction as well as methanol extract of R. crategifolius roots are necessary for further studies as a potent inhibitor of the growth of cancer cells.

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Quantitative Risk Assessment of the Chemical Facilities by KS-RBI Program (위험기반검사 프로그램에 의한 화학설비의 정량적 위험성 평가)

  • Kim, Tae-Ok;Lee, Hern-Chang;Choi, Sung-Kyu;Jo, Ji-Hoon;Ham, Byeong-Ho
    • Journal of the Korean Institute of Gas
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    • v.11 no.4
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    • pp.23-28
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    • 2007
  • Damage ranges of accidents of the chemical facilities were estimated by the KS-RBI(Ver.3.0) program supporting the quantitative cause analysis, and the consequences were compared with the results of K-CARM(Ver2.0) program which assesses the quantitative risk in an usual method. As a result we found that the consequences of the KS-RBI program were similar to those of the K-CARM program. Therefore, the KS-RBI program could be applied to the quantitative risk assessment. In addition, it can be safely said that through appling the damage ranges of accidents by weighted average, industrial sites can come up with the effective plans of mitigation and emergency.

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Effects of Goat Milk Yogurt Supplemented with Citrus Concentrate on Blood Glucose and Serum Lipids in Diabetic Rats (밀감농축액 첨가 산양발효유가 당뇨병 유발 랫드의 혈당 및 혈액지질에 미치는 영향)

  • Ham, Jun-Sang;Shin, Ji-Hye;Jang, Ae-Ra;Jeong, Seok-Geun;Park, Kwang-Wook;Kim, Hyun-Uk;Kang, Su-Yeon;Hwang, Hye-Joong;Lee, Wan-Kyu
    • Food Science of Animal Resources
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    • v.28 no.4
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    • pp.445-450
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    • 2008
  • The effects of fermented goat milk supplemented with citrus concentrate on blood glucose levels in streptozotocin-nicotinamide-induced diabetic rats were examined. Streptozotocin-nicotinamide-induced diabetic rats (type II) were divided into five experimental groups treated with metformin, goat milk, fermented goat milk, fermented goat milk containing citrus concentrate, or no supplementation (control). The rats in each group were examined weekly for blood levels of glucose, total cholesterol, triglyceride. HDL-cholesterol, LDL-cholesterol. and body weight. On the $24^{th}$ day of the experiment, an oral glucose tolerance test (OGTT) was carried out. Administration of fermented goat milk to the diabetic rats significantly decreased blood glucose and triglyceride levels, while administration of metformin (33.3 mg/kg body weight) did not significantly lower blood glucose levels. Fermented goat milk containing citrus concentrate caused a significant decrease in blood glucose levels in the OGTT at 30 min. This study shows that supplementation with fermented goat milk containing citrus concentrate may be a practical method of reducing blood glucose levels in type II diabetics.

Reduction in Lesion Incidence in Pork Carcass Using Transdermal Needle-free Injection of Foot-and-Mouth Disease Vaccine

  • Ko, Eun Young;Cho, Jaesung;Cho, Jin Ho;Jo, Kyung;Lee, Seung Hwan;Chung, Yoon Ji;Jung, Samooel
    • Food Science of Animal Resources
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    • v.38 no.6
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    • pp.1155-1159
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    • 2018
  • Foot-and-mouth disease (FMD) is an infectious disease affecting pigs. The control of FMD in swine husbandry is very important because its outbreak results in a vast economic loss. FMD vaccination has effectively controlled FMD; however, it results in economic loss associated with the incidence of lesions in the pork meat at the injection site. The objective of this study was to investigate the effects of transdermal needle-free injection (NFI) of the FMD vaccine on the incidence of lesions at the injection site. Pigs (n=493) in the control group were vaccinated with the FMD vaccine using a commercial syringe needle, while 492 pigs in the transdermal NFI group received the FMD vaccine using a needle-free gas-powered jet injector. After the slaughter of the pigs, the incidence of lesions at the injection site of all pigs was checked by plant workers. The result of this study showed that the incidence of lesions in the pork ham from pigs vaccinated with NFI was 14.82% lower than that in control pigs (p<0.01). In addition, lesions generated in the NFI group were found just in the subcutaneous tissue. Therefore, the incidence of lesions at the injection site in pork from pigs vaccinated with the FMD vaccine can be effectively reduced by using transdermal NFI rather than a conventional syringe needle.

Fabrication and Performance Demonstration of the 20kW Class Inverted-type Cross-flow Turbine Based on Computational Fluid Dynamics Analysis (전산유체역학 해석에 기반한 20kW급 도립형 횡류수차의 제작 및 성능 실증)

  • Ham, Sangwoo;Choi, Ji-Woong;Jeong, Changho;Kim, Taeyun;Choi, Sangin;Jin, Glenn Young;Lee, Jeong Wan;Ha, Hojin
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.20 no.2
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    • pp.107-119
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    • 2021
  • The cross-flow turbine is one of the most famous and widely used hydraulic power systems for a long time. The cross-flow turbine is especially popular in many countries and remote regions where off-grided because of its many benefits such as low cost, high efficiency at low head, simple structure, and easy maintenance. However, most modern turbines, including the cross-flow turbine, are unsuitable for the ultra-low head situation, known as less than 3m water head or zero head with over 0.5m/s flow velocity. In this study, we demonstrated a 20kW class inverted-type cross-flow turbine's performance. First, we reevaluated our previous studies and introduced how to design the inverted-type cross-flow turbine. Secondly, we fabricated the 20kW class inverted-type cross-flow turbine for the performance test. And then, we designed a testbed and installed the turbine system in the demonstration facility. In the end, we compare the demonstration with its previous CFD results. The comparing result shows that both CFD and real model fitted on guide vane angle at 10 degrees. At the demonstration, we achieved 42% turbine efficiency at runner speed 125 RPM.

Observations of the Aurora by Visible All-Sky Camera at Jang Bogo Station, Antarctica

  • Jee, Geonhwa;Ham, Young-Bae;Choi, Yoonseung;Kim, Eunsol;Lee, Changsup;Kwon, Hyuckjin;Trondsen, Trond S.;Kim, Ji Eun;Kim, Jeong-Han
    • Journal of Astronomy and Space Sciences
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    • v.38 no.4
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    • pp.203-215
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    • 2021
  • The auroral observation has been started at Jang Bogo Station (JBS), Antarctica by using a visible All-sky camera (v-ASC) in 2018 to routinely monitor the aurora in association with the simultaneous observations of the ionosphere, thermosphere and magnetosphere at the station. In this article, the auroral observations are introduced with the analysis procedure to recognize the aurora from the v-ASC image data and to compute the auroral occurrences and the initial results on their spatial and temporal distributions are presented. The auroral occurrences are mostly confined to the northern horizon in the evening sector and extend to the zenith from the northwest to cover almost the entire sky disk over JBS at around 08 MLT (magnetic local time; 03 LT) and then retract to the northeast in the morning sector. At near the magnetic local noon, the occurrences are horizontally distributed in the northern sky disk, which shows the auroral occurrences in the cusp region. The results of the auroral occurrences indicate that JBS is located most of the time in the polar cap near the poleward boundary of the auroral oval in the nightside and approaches closer to the oval in the morning sector. At around 08 MLT (03 LT), JBS is located within the auroral oval and then moves away from it, finally being located in the cusp region at the magnetic local noon, which indicates that the location of JBS turns out to be ideal to investigate the variabilities of the poleward boundary of the auroral oval from long-term observations of the auroral occurrences. The future plan for the ground auroral observations near JBS is presented.