• Journal of Science Education
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• v.43 no.2
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• pp.258-269
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• 2019

This study developed an instrument for measuring STEAM education effectiveness focused on key competencies of STEAM. This study performed literature reviews on the prior studies associated with the STEAM education and completed a pilot instrument through reflective reviews by external experts. A pilot study was administered to a total of 408 students and finalized by statistical analyses such as reliability check and exploratory factor analysis. The factors of the final instrument were identified as convergence (seven items), creativity (eleven items), challenge (five items), and care (nine items). The Cronbach' ${\alpha}$ for each construct ranged from .849 to .929 turned out to be reliable. This instrument can be utilized for measuring the effectiveness of the STEAM education on students' key competencies.

• PNF and Movement
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• v.20 no.3
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• pp.307-319
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• 2022

Purpose: This study aimed to investigate the perceptions of tele-physical therapy of health and non-health majors. It can provide basic research data for the provision of medical services in the future by identifying the level of awareness of the need for tele-physical therapy and the factors that affect it. Methods: The subjects were adults aged 20 to 29 in Korea, with 199 participants consisting of 83 health majors and 116 non-health majors. The survey was conducted over a period of 14 days. The survey comprised 19 questions, including 10 questions about general characteristics and 9 questions about tele-physical therapy recognition. The results were statistically analyzed using a statistical package program. Results: There was a significant difference between the two groups regarding the recognition of tele-physical therapy, with an average of 2.64 points in health majors and an average of 1.71 points in non-health majors, showing a low overall score. There was no significant difference in perception of the necessity of tele-physical therapy, with an average of 3.71 points in health majors and an average of 3.49 points in non-health majors, showing a high score, which was defined as a score of 3 or higher. Conclusion: Health and non-health majors showed low awareness of tele-physical therapy. A high level of perceived necessity for tele-physical therapy was shown. In the perception of tele-physical therapy in health majors, 'awareness', 'health improvement', and 'convenience' affect the perception of the necessity of tele-physical therapy. In non-health majors, 'knowledge and skills', 'health improvement', 'expected treatment satisfaction', and 'resolving restrictions on hospital visits' affect the perception of the necessity of tele-physical therapy.

• Toxicological Research
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• v.35 no.2
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• pp.191-200
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• 2019

Alismatis rhizoma (AR), the dried rhizome of Alisma orientale (Sam.) Juzep, is a well-known, traditional medicine that is used for the various biological activities including as a diuretic, to lower cholesterol and as an anti-inflammatory agent. The present study was carried out to investigate the potential toxicity of the Alismatis rhizoma aqueous extract (ARAE) following 90-day repeated oral administration to Sprague-Dawley rats. ARAE was administered orally to male and female rats for 90 days at 0 (control), 500, 1,000 and 2,000 mg/kg/day (n = 10 for male and female rats for each dose). Additional recovery groups from the control group and high dose group were observed for a 28-day recovery period. Chromatograms of ARAE detected main compounds with four peaks. Treatment-related effects including an increase in the red blood cells, hemoglobin, hematocrit, albumin, total protein, and urine volume were observed in males of the 2,000 mg/kg/day group (p < 0.05). However, the diuretic effect of ARAE was considered, a major cause of hematological and serum biochemical changes. The oral no-observed-adverse-effect level (NOAEL) of the ARAE was > 2,000 mg/kg/day in both genders, and no target organs were identified.

• Korean Journal of Radiology
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• v.23 no.11
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• pp.1078-1088
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• 2022

Objective: To develop and validate a model using radiomics features from apparent diffusion coefficient (ADC) map to diagnose local tumor recurrence in head and neck squamous cell carcinoma (HNSCC). Materials and Methods: This retrospective study included 285 patients (mean age ± standard deviation, 62 ± 12 years; 220 male, 77.2%), including 215 for training (n = 161) and internal validation (n = 54) and 70 others for external validation, with newly developed contrast-enhancing lesions at the primary cancer site on the surveillance MRI following definitive treatment of HNSCC between January 2014 and October 2019. Of the 215 and 70 patients, 127 and 34, respectively, had local tumor recurrence. Radiomics models using radiomics scores were created separately for T2-weighted imaging (T2WI), contrast-enhanced T1-weighted imaging (CE-T1WI), and ADC maps using non-zero coefficients from the least absolute shrinkage and selection operator in the training set. Receiver operating characteristic (ROC) analysis was used to evaluate the diagnostic performance of each radiomics score and known clinical parameter (age, sex, and clinical stage) in the internal and external validation sets. Results: Five radiomics features from T2WI, six from CE-T1WI, and nine from ADC maps were selected and used to develop the respective radiomics models. The area under ROC curve (AUROC) of ADC radiomics score was 0.76 (95% confidence interval [CI], 0.62-0.89) and 0.77 (95% CI, 0.65-0.88) in the internal and external validation sets, respectively. These were significantly higher than the AUROC values of T2WI (0.53 [95% CI, 0.40-0.67], p = 0.006), CE-T1WI (0.53 [95% CI, 0.40-0.67], p = 0.012), and clinical parameters (0.53 [95% CI, 0.39-0.67], p = 0.021) in the external validation set. Conclusion: The radiomics model using ADC maps exhibited higher diagnostic performance than those of the radiomics models using T2WI or CE-T1WI and clinical parameters in the diagnosis of local tumor recurrence in HNSCC following definitive treatment.

• Food Science and Biotechnology
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• v.17 no.1
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• pp.58-65
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• 2008

To see the possibility of irradiation as an alternative to ultra high temperature (UHT) sterilization, the quality characteristics of milk were analyzed. Milk treated by UHT ($135^{\circ}C$ for 4 sec) and irradiation at higher than 3 kGy showed no viable counts after 7 days of storage at $4^{\circ}C$. The contents of certain amino acids of milk, such as Arg, Asp, Glu, Ile, Leu, Lys, Pro, Ser, Thr, and Tyr, were lower in irradiated groups at 10 kGy than in UHT-treated one, but no difference was observed between irradiated milks at less than 5 kGy and UHT. The capillary electrophoresis (CE) patterns of the milk irradiated at 10 kGy showed a similar trend to the raw milk, low temperature long time (LTLT, $63^{\circ}C$ for 30 min), and high temperature short time (HTST, $72^{\circ}C$ for 15 sec) treated. However, the CE pattern of UHT-treated milk was different. Rennet coagulation test agreed with the CE results, showing that all milk samples were coagulated by rennet addition except for UHT-treated milk after 1 hr. These results suggest that irradiation of milk reduce the content of individual amino acids but it may not induce severe conformational change at a protein level when compared with UHT treatment.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.29 no.2
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• pp.131-140
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• 2016

Recent destructions of outdoor signboards have frequently been caused by strong wind, resulting in damage on the property and human livelihood. One of the major causes of the problems is inadequate implementation of structural design code to the outdoor signboards which are vulnerable to wind. This leads to this paper to present the design guideline of wind-resistant outdoor signboards. In order to estimate the design wind speed, basic wind speeds over Korea suggested by KBC(2015)(revision) are corrected with land surface roughness and topography of the terrain and installation height of the signboard. This paper also suggested the procedure of wind load estimation for different types of outdoor signboards; wall attached type, wall ribbed type and ground erected type. Since the process involves complex calculation to some extent, this paper presents summarized version of wind load estimation from non-professional point of view.

• Korean Journal of Materials Research
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• v.28 no.8
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• pp.459-465
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• 2018

This paper presents a study of the microstructure and mechanical properties of commercial high-hardness armor (HHA) steels tempered at different temperatures. Although the as-received specimens of all the steels exhibit a tempered martensite structure with lath type morphology, the A steel, which has the smallest carbon content, had the lowest hardness due to reduced solid solution hardening and larger lath thickness, irrespective of tempering conditions. As the tempering temperature increases, the hardness of the steels steadily decreases because dislocation density decreases and the lath thickness of martensite increases due to recovery and over-aging effects. When the variations in hardness plotted as a function of tempering temperature are compared with the hardness of the as-received specimens, it seems that the B steel, which has the highest yield and tensile strengths, is fabricated by quenching, while the other steels are fabricated by quenching and tempering. On the other hand, the impact properties of the steels are affected by specimen orientation and test temperature as well as microstructure. Based on these results, the effect of tempering on the microstructure and mechanical properties of commercial high-hardness armor steels is discussed.

• Journal of Applied Biological Chemistry
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• v.61 no.1
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• pp.39-46
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• 2018

Column chromatographic separation of the MeOH extract from the roots of Dicentra spectabilis yielded fourteen compounds, menisdaurin (1), menisdaurilide (2), trans-N-p-coumaroyltyramine (3), trans-N-p-feruloyltyramine (4), 4-O-feruloylquinicacid (5), chlorogenic acid (6), 3-O-feruloylquinicacid (7), ferulic acid (8), protopine (9), Kaempferol 3,7-di-O-${\beta}-{\text\tiny{D}}$-glucopyranoside (10), kaempferol 3-O-${\beta}-{\text\tiny{D}}$-glucopyranosyl-7-O-${\alpha}-{\text\tiny{L}}$-rhamnopyranoside (11), ${\alpha}-rhamnoisorobin$ (12), astragalin (13), and nicotiflorin (14). Their structures were determined on the basis of NMR spectroscopic data. Among them, compound 1, 3-8, and 10-14 isolated from this plant were reported for the first time. The isolated compounds (1-14) were tested for nitric oxide (NO) inhibitory activity on lipopolysaccharide-stimulated RAW 264.7 cells. Compound 3, 4 and 12 significantly inhibited NO production. Moreover, Compound 3 suppressed pro-inflammatory cytokines ($TNF-{\alpha}$, $IL-1{\beta}$ and IL-6) in a dose- dependent manner. These data suggest that compound 3 possess anti-inflammatory activity and might be useful natural materials for development of anti-inflammatory agent.

• Asian Oncology Nursing
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• v.12 no.4
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• pp.305-313
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• 2012

Purpose: This study was done to clarify the effects of foot reflexology on peripheral neuropathy, symptom distress, anxiety and depression in cancer patients treated with oxaliplatin. Methods: A quasi-experimental design was employed. Changes in the variables were evaluated to test the effects of foot reflexology. Participants were cancer patients treated with oxaliplatin (experimental group 14 and control group 17). Peripheral neuropathy, symptom distress, anxiety and depression were measured before and after reflexology. Data were collected from October, 2010 to April, 2011. ${\chi}^2$-test, Fisher's exact test, t-test, Wilcoxon signed rank test and the Mann-Whitney U test were used to analyze the data. Results: The experimental group who received foot reflexology experienced less peripheral neuropathy and symptom distress than the control group. There was no difference in anxiety and depression between the experimental and control group. Conclusion: The foot reflexology program adopted in this study was found to be an effective method to reduce peripheral neuropathy and symptom distress. We recommend foot reflexology for patients with chemotherapy induced peripheral neuropathy.

• Knowledge Management Research
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• v.15 no.3
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• pp.37-66
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• 2014

Since social network service (SNS) has been widely used as a effective way for people to connect and communication with each other, the use of corporate SNS account also has increased. However, compared to a private SNS account, only few people have a continuous relationship with their corporate SNS account because the use of corporate SNS account tends to be one-time and temporary activity whenever the users just need events and information. Given the psychological side effects of using SNS, the relative lack of empirical studies on the impacts of emotional factor in SNS prevents the deeper understanding of the intention to continuous using corporate SNS account. Therefore, this study aims to explore key determinants of the intension to continuous using the corporate SNS account from a habit and emotional perspective. To bridge research gap, we attempt to divide emotional factor into the following 5 factors based on Mehrabian and Russell model (1974): intimacy, enjoyment (positive factor), privacy concern, anxiety (negative factor), arousal (arousal factor) and (dominant factor). The basic model is proposed to explore the effects of habit and emotional factors on the intension to continuous using the corporate SNS account. We then examine how the effects of habit and emotional factors differ depending on social media types (e.g., facebook and twitter). The results indicates that habit is related to emotional factors, and each emotional factor differently influences the intension to continuous using the corporate SNS account. The results also confirm that the effects of the habit and emotional factors on the intension to continuous using the corporate SNS account differ according to social media types. This study provides practical and useful guidance and the strategic marketing insight for managers in maintaining and improving the intension to continuous using the corporate SNS account.