• Title/Summary/Keyword: Lee Gyu-Bo

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The Association between Cancer Incidence and Family Income: Analysis of Korean National Health Insurance Cancer Registration Data

  • Kim, Ji-Man;Kim, Hee-Moon;Jung, Bo-Young;Park, Eun-Cheol;Cho, Woo-Hyun;Lee, Sang-Gyu
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1371-1376
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    • 2012
  • Background: Economic status is known to be directly or indirectly related to cancer incidence since it affects accessibility to health-related social resources, preventive medical checkups, and lifestyle. This study investigates the relationship between cancer incidence and family income in Korea. Methods:Using the Korean National Health Insurance cancer registration data in 2009, the relationship between their family income class and cancer risk was analyzed. The age-standardized incidence rates of the major cancers were calculated for men and women separately. After adjusting for age, residential area, and number of family members, cancer risks for major cancers according to family income class were estimated using a logistic regression model. Results: In men, the risk of stomach cancer for Income Class 5 (lowest) was 1.12 times (95% CI 1.02-1.23) higher than that of Income Class 1 (highest), for lung cancer 1.61 times (95% CI 1.43-1.81) higher, for liver cancer 1.22 times (95% CI 1.08-1.37) higher, and for rectal cancer 1.37 times higher (95% CI 1.18-1.59). In women, the risk of stomach cancer for Income Class 5 was 1.22 times higher (95% CI 1.08-1.37) than that for Income Class 1, while for cervical cancer it was 2.47 times higher (95% CI 2.08-2.94). In contrast, in men, Income Class 1 showed a higher risk of thyroid cancer and prostate cancer than that of Income Class 5, while, in women the same was the case for thyroid cancer. Conclusions: The results show the relationship between family income and cancer risk differs according to type of cancer.

Experimental Research of Hyunggaeyunkyotanggamibalhyobang (HYGBH) on Atopic Dermatitis Treatment (형개련교탕가미발효방(荊芥連翹湯加味醱酵方)의 항아토피피부염 효능에 관한 실험적 연구)

  • Hwang, Yun-Gyu;Park, Bo-Kyung;Gim, Seon-Bin;Lee, Yong-Koo;Jin, Mi-Rim;Kim, Dong-Hee
    • Journal of Haehwa Medicine
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    • v.19 no.2
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    • pp.85-100
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    • 2011
  • In order to investigate the efficacy of HYGBH on atopic dermatitis, various immune related factors were studied. The results and conclusions are as follows. Atopic dermatitis symptoms were improved in HYGBH treated group and significant decrease in dermatitis index were observed in 12 and 14 weeks. HYGBH treated group showed significant decrease in CD4+, CD3+/CD69+ immune cell ratio in PBMC by 18% and 40.6% respectively. HYGBH treated group showed significant decrease in CD3+, CD11b+/Gr-1+ immune cell ratio in dorsal skin by 44.6% and 53.1% respectively. HYGBH treated group showed significant decrease in IL-4, IFN-${\gamma}$ in spleen by 29.5%, 7.7% respectively. HYGBH treated group showed decrease in the expression of IL-5, IL-13, IL-17 and histamine by 21%, 9.6%, 14%, and 32.2% respectively. Also the group showed decrease in the expression of IgE by 6.8% respectively. HYGBH treated group showed significant decrease in the transcription of IL-5 and IL-3 mRNA in skin by 35.5% and 23.2% respectively. The results above indicated that treatment of HYGBH improved atopic dermatitis symptoms by anti-oxidant activity as well as immune modulation activity as a clinical evidence. Also, to increase the application of fermented oriental medicine, different fermentation conditions using various microbial strains should be accumulated as the clinical evidence in the future.

Study on the Unburned Carbon and NOx emission of High Moisture Coal (고수분탄의 건조에 따른 미연분 및 NOx 배출 특성에 관한 연구)

  • Ahn, Seok-Gi;Kim, Jung-Woo;Kim, Gyu-Bo;Lee, Si-Hyun;Jeon, Chung-Hwan
    • Journal of Energy Engineering
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    • v.25 no.4
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    • pp.53-61
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    • 2016
  • Unburned Carbon(UBC) and NOx emissions from High-moisture coal and Dried coal were investigated in Drop Tube Furnace(DTF). When the same amount of the High-moisture coal and Dried coal were oxidized in DTF, the results show that UBC and NOx emissions of Dried coal case is higher than High-moisture coal case. As the moisture in coal decreases from 40% to 10%, the average gas temperature increases but the moisture concentration in DTF decreases. As the wall temperature increases from $900^{\circ}C$ to $1500^{\circ}C$, the UBC decreases and NOx emissions increases. Especially, the difference for UBC between High-moisture coal and Dried coal decreases with increasing wall temperature.

Development of Variable Deposition manufacturing for Ethylene Vinyl Acettecopolymer (EVA를 이용한 가변 용착 쾌속 조형 공정의 개발)

  • Lee, Sang-Ho;Sin, Bo-Seong;Jeong, Jun-Ho;An, Dong-Gyu;Yang, Dong-Yeol
    • Journal of the Korean Society for Precision Engineering
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    • v.17 no.9
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    • pp.189-195
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    • 2000
  • RP techniques have their unique characteristics according to the working principles : star-stepped surface of parts due to layer-by-layer stacking low build speed caused by line-by-line solidification to fish one layer and post processing to improve surface finish etc The objective of this study is to propose a new RP technique Variable Deposition Mnanufacturing (VDM) which can make up for the disadvantages of the existing RP techniques and to develop an apparatus to implement the technique. The proposed process can greatly reduce the build time and improve the surface finish of parts generated. Experiments are carried out to obtain the range of temperature of molten material to maintain its fluidity and to investigate the effect of gas cooling on the preservation of the slopes. Some simple shapes such as a line-shape an S-shape and a circle-shape are fabricated from Ethylene Vinyl Acetatecopolymer(EVA) In order to examine the applicability of VDM to more general shapes a tensile specimen and a yo-yo shape were manufactured by the proposed RP method using EVA material as a trial approach. The current basic study shows a high potential of practical use of the proposed VDM process to prototyping of a general three-dimensional shape.

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Effects of Seedling Age on Growth and Yield of Machine Transplanted Rice in Southern Plain Region

  • Kim, Sang-Su;Kim, Bo-Kyeong;Choi, Min-Gyu;Back, Nam-Hyun;Choi, Weon-Young;Lee, Sean-Yong
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.44 no.2
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    • pp.122-128
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    • 1999
  • Three rice cultivars, Namweonbyeo (early maturing), Hwaseongbyeo (medium maturing) and Dongjinbyeo (medium-late maturing) were trans-planted with 3 different seedling ages to investigate their growth habits and to improve the cultural method in paddy fields in the southern plain area of the Honam region in 1993. The 10-day old seedlings had more vigorous elongation of plant height and higher tillering ability but lower effective tiller rate, when compared with 35-day or 40-day old seedlings. Leaf area index and top dry weight were lower in 10-day old seedlings up to 40 days after transplanting but thereafter, were not different among seedlings ages. CGR was later in 10-day old seedlings, up to 30 days after transplanting, but in 30 to 40 days after transplanting, it was reversed. RGR was the highest in infant seedlings to 40 days after trans-planting, while in 50 days after transplanting, it was reversed. Panicle number and spikelet number per square meter were the highest in 40-day old seedlings, next highest in 35-day old seedlings and the lowest and in adult seedlings up to 40 days after transplanting, while spikelet number per panicle was vice versa. Milled rice yield did not vary significantly by seedling ages, but among the varieties, it was less in Hwaseongbyeo compared with Naweonbyeo and Dongjnbyeo.

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Effect of Low-Dose Radiation on Quality Characteristics of Takju (저선량 방사선 처리가 탁주 품질특성에 미치는 영향)

  • Lee, Yun-Gyu;Tak, Eun-Mi;Kim, Bo-Mi-Na;Seo, Choung-Won;Choi, Seung-Hwan;Shin, Yong-Seob;Kim, Seon-Chil
    • Korean Journal of Digital Imaging in Medicine
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    • v.13 no.3
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    • pp.133-137
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    • 2011
  • This research investigated how low dose radiation affected the quality characteristics of Takju. The treatment group were the quality characteristics of control group, Takju treated by radiation of separate 4, 7, 10 Gy and sterilized Takju. We measured pH, titratable acidity, alcohol, brix, total viable cell count, Hunter's color values, sensory characteristic. As a result, We discovered there were minute changes in pH, titratable acidity, alcohol, brix, total viable cell count. Likewise, The color appeared changes on separate radiation dose. In the sensory characteristic, People's preference ranked better than average level according to priority Takju treated by 4, 7, 10 radiation. In conclusion, Low dose radiation had little effect on the quality characteristics of Takju. However, Takju received a favorable review by some people In test of taste such as after taste. So We thought, such as preservation, the research using the radiation should be continually conducted.

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The simultaneous determination of germanium and selenium in plant by hydride vapour generator inductively coupled plasma mass spectrometry (HVG-ICPMS을 이용한 식물체 중 게르마늄과 셀레늄의 동시분석 연구)

  • Ham, Yong-Gyu;Kim, Bo-Kyong;Kwon, Young-Uk;Baek, Hyo-Hyu;Lee, Seok-Ki
    • Analytical Science and Technology
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    • v.24 no.3
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    • pp.159-167
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    • 2011
  • In this study, the hydride vapour generator inductively coupled plasma mass spectrometry (HVGICPMS) was applied as the new analytical method to show the high accurate and reproductive data analysing the amounts of selenium and germanium being existed inside a system of plant. In order to decrease the interference effects, such as ion and molecular interference. Mini torch was used into the ICPMS instead of the conventional torch. At conditions of the different kinds and concentrations of acid solution, the different reductive conditions for composing hydride, and the different methods for making ash, the contents of selenium and germanium in lettuce were analysed. The inspection of yields and data comparison from SRM-1574 and -1570a were used for increasing the accuracy of this analysis.

A Study on the Methodology for a Clinical Trial of an Antidepressive Korean Herb by Comparison with St. John's Wort Trials (성요한초제제 임상시험 고찰을 통한 한약기원 항우울제 임상시험 방법론 연구)

  • Jung, Hee;Lee, Ji-Hyung;Jang, Bo-Hyoung;Ko, Seong-Gyu
    • The Journal of Internal Korean Medicine
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    • v.28 no.2
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    • pp.363-376
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    • 2007
  • Objectives : This study was undertaken to learn what should be considered in a good clinical trial investigating a herbal medicine as an antidepressant. Methods : Five well-designed clinical trials published from 2000 to 2006 investigating SJWE in depressive disorder were selected. The trials were reviewed and compared in terms of methodology such as trial design, patient selection, efficacy & safety evaluation, and so on. On the basis of this review of the trials and the regulations and guidelines of KFDA, we suggest some points to be considered for a good clinical trial of a herb for depression. Results : Although every trial had its own unique design, procedure, objectives and so on, all trials used randomizing and double blinding methods. If there is no ethical problem, a placebo-controlled design should be considered in a herbal antidepressant clinical trial for depression. Conclusions : Some points to be considered in an optimal & good clinical trial for an antidepressive herbal medicine were suggested as follows: 1) randomizing and double blinding manner is essential, 2) if there is no ethical problem, placebo control design should be considered, 3) the trial period should be 6 weeks, 4) out-patients will be recruited as subjects, 5) investigators will be well-trained psychiatrists or medical doctors, 6) the number of subjects should be calculated by statistical methods, 7) subjects should be diagnosed by DSM-IV criteria, 8) subjects who have current risk of committing suicide should be excluded, etc.

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Study on Soot Primary Particle Size Measurement in Ethylene Diffusion Flame by Time-Resolved Laser-Induced Incandescence (시분해 레이저 유도 백열법을 이용한 에틸렌 확산 화염에서의 매연 일차입자크기 측정에 관한 연구)

  • Kim Gyu-Bo;Cho Seung-Wan;Lee Jong-Ho;Jeong Dong-Soo;Chang Young-June;Jeon Chung-Hwan
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.30 no.10 s.253
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    • pp.973-981
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    • 2006
  • Recently there is an increasing interest in particulate matter emission because of new emission regulations, health awareness and environmental problems. It requires to improve particulate measurement techniques as well as to reduce soot emissions from combustion systems. As mentioned above, it is demanded that reduction techniques together with measurement techniques of exhausted particulate matters in combustion systems such as vehicles. However, measurement techniques of particulate matters should be prior to reduction techniques of that because it is able to know an increase and a decrease of exhausted particulate matters when measured particulate matters. Therefore, in this study, we report the measurement of soot primary-particle size using time-resolved laser induced incandescence (TIRE-LII) technique in laminar ethylene diffusion flame. As an optical method, laser induced incandescence is one of well known methods to get information for spatial and temporal soot volume fraction and soot primary particle size. Furthermore, TIRE-LII is able to measure soot primary particle size that is decided to solve the decay ate of signal S $(t_1)$ and S $(t_2)$ at two detection time. In laminar ethylene diffusion flame, visual flame height is 40 mm from burner tip and measurement points are height of 15, 20, 27.5, 30 mm above burner tip along radial direction. As increasing the height of the flame from burne. tip, primary particle size was increased to HAB(Height Above Burner tip)=20mm, and then decreased from HAB=27.5 mm to 30 mm. This results show the growth and oxidation processes for soot particles formed by combustion.

Anticonvulsant, Antioxidant Effect of Gungchihwadam-jeon (궁치화담전 투여가 PTZ 경련 유발시 뇌조직 중 경련 및 산화 관련물질에 미치는 영향)

  • Kim Lak hyung;Kwon Bo Hyung;Lee Kwang Gyu;Oh Chan Ho
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.1
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    • pp.206-213
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    • 2004
  • This study was performed to evaluate the anticonvulsant, antioxidant effect of modified formulas Korean traditional medicine Gungchihwadam-Jeon(GCHDJ). The extract of GCHDJ was administered (p.o.) to mice for 14 days in anticonvulsant and antioxidant tests. The pretreatment of GCHDJ extract prohibited the pentylenetrazol(PTZ)-induced convulsion in PTZ-induced convulsion, lowered level of brain r-aminobutyric acid(GABA) was restored by the pretreatment of GCHDJ. Increased level of brain glutamic acid was lowered to normal state by GCHDJ, and increased activity of brain r-aminobutyric acid transaminase(GABA-T) was reduced by GCHDJ. In PTZ-induced convulsion, increased level of brain lipid peroxide was lowered to normal state by the pretreatment of GCHDJ. Increased activity of brain xanthine oxidase(XOD) was lowered to normal state by GCHDJ, and increased activity of brain aldehyde oxidase lowered to normal state by GCHDJ. In PTZ-induced convulsion, increased activities of superoxide dismutase(SOD) and catalase in brain were lowered by the pretreatment of GCHDJ, whereas increased level of glutathione and increased activity of gluthathione peroxidase in brain were not changed significantly. Above results suggest that GCHDJ have anticonvulsant. antioxidant effect. That seems to be strongly related with the levels of GABA, glutamate, lipid peroxide and the activities of GABA-T, XOD, aldehyde oxidase, SOD, catalase in brain tissue. From these results, GCHDJ could be applied to various convulsive disorders.