• 동의생리병리학회지
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• 제31권3호
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• pp.153-158
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• 2017

As social interest in acne treatment has grown, various external preparations have been developed and studied. So, we investigated the external prescription which can treat acne in medical classics, then reviewed and divided it by dynasty. The data for analysis of Herbal formula was taken from 'medicine Dictionary of traditional Chinese medicine prescriptions(中醫方劑大辭典)'. 31 external medicines were searched, 3 were before song(宋) dynasty, 11 were Song(宋) dynasty, 11 were Yuan(元) dynasty, 7 were Ming(明) dynasty and 7 were Qing(淸) dynasty. The recipe and usage were only making them pill(丸) and paste(膏) using grinded medicinal herbs, then rubbing to face. As the age developed, unique manufacturing process(i.e fermentation method), and usage(i.e time-based usage, herbal medicine extracts for wash) were proposed. The external application with oriental medicine for acne used with Angelicae Gahuricae Radix(n=12), Bletillae Rhizoma(n=8), Syzygii Flos, Saposhnikoviae Radix(n=7) and so on. In particular, Bletillae Rhizoma was searched with high frequency in this study, but it was not included or studied in patent composition. The results of this study will provide basic data for future experiments and clinical studies.

• 대한한방내과학회지
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• 제33권4호
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• pp.476-484
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• 2012

Objectives : The purpose of this study was to report the clinical characteristics of glossodynia patients and effects of traditional Korean treatment on glossodynia and to gather data in order to carry out future study. Methods : We surveyed 40 glossodynia patients visiting the Department of Korean Internal Medicine of Stroke and Neurological Disorders Center, Kyung Hee University Hospital at Gangdong and analyzed their glossodynia questionnaires, examination results, and progression of symptoms. Results : In Glossodynia patients the average age was 62.4 years old. Glossodynia was more prevalent in females than males (5.67:1). Red tongue color, white fur, and fissured tongue were observed most often. The average glossodynia duration was 36.1 months and the average glossodynia degree was VAS 5.6. The most commonly appearing symptom was burning sense, and dryness of tongue. In Korean medicine diagnosis, Yin, deficiency, Tae-eum was most commonly diagnosed. In herbal medicine, Gamichungsim-tang was the most frequently prescribed. In laboratory tests, zinc deficiency was the most common result. In heart rate variability (HRV), average SDNN was 34.03 and average LF/HF ratio was 2.11. Of 40 patients, 23 completed treatment and their pain was relieved from average VAS 5.52 to VAS 3.63. Pre-and post-treatment results showed a significant difference. The average duration of treatment was 34.91 days. Conclusions : The results of this study suggest that Korean medical approach and treatment for glossodynia could be effective. Further study should be conducted for more valuable information.

• 한국의사학회지
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• 제33권1호
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• pp.31-41
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• 2020

Purpose : This study compares prescriptions in the 1901 edition of the Donguisusebowon (東醫壽世保元) and the 1901 edition of 24 Revised Tae-eum constitution prescriptions (新定太陰人病應用要藥二十四方) (1901PCDT) with medical herbs found in classical texts. This study also examines whether to include patterns which compose medical herbs for the person of Tae-eum constitution (太陰人). Method : The prescriptions for Tae-eum-in in the Shinchukbon and the ingredients of medical herbs of the prescriptions of the Complete Works of Zhang Jingyue (景岳全書), Secret Works of Universal Benefit (廣濟秘笈), Treasured Mirror of Eastern Medicine (東醫寶鑑), Comprised Edition for Formulas (方藥合編), Protecting Essence for Longevity (壽世保元), Introduction to Medicine (醫學入門), New Book for Saving People (濟衆新編 ENGLISH), and Compendium of Local Medicinals and Formulas (鄕藥集成方) were input into a database. The prescriptions were examined and combinations of medical herbs used to treat the person of Tae-eum constitution were noted. Result : Among the prescriptions for the person of Tae-eum constitution, similar examples of the 17 prescriptions of Kudzu Decoction to Relieve the Muscles (葛根解肌湯), Regulate the Stomach and Coordinate the Purity Decoction (調胃升淸湯), Clear the Heart and Lotus Pip Decoction (淸心蓮子湯), Decoction for Stabilizing Asthma with Ephedra (麻黃定喘湯), Profuse Heat and Sparse Cold Decoction (熱多寒少湯), Decoction for Coordinating Qi with Kudzu (葛根承氣湯), Major Decoction for Coordinating Qi with Kudzu (葛根大承氣湯), Minor Decoction for Coordinating Qi with Kudzu (葛根小承氣湯), Decoction for Dispersing the Exterior with Ephedra (麻黃發表湯), Boost the Lung Essence Decoction (補肺元湯), Major Supplementing Decoction with Deer Antler Velvet (鹿茸大補湯), Boosting Black Essence Pill (拱辰黑元丹), Honeylocust Fruit and Rhubarb Decoction (皂角大黃湯), Kudza and Duckweed Decoction (葛根浮萍湯), Sweet Flag and Polygala Powder (石菖蒲遠志散), Liriopis and Polygala Decoction Powder (麥門冬遠志散), and Cattle Gallstone Formula to Clear the Heart (牛黃淸心元) were found in important ancient literature and Dried Chestnut and Holotrichia Decoction (乾栗蠐螬湯) and Dried Chestnut and Tree of Heaven Root Bark Decoction (乾栗樗根皮湯) are the combination originally set by Lee Jema. Conclusion : Because 70.8% of the prescriptions in 1901PCDT could be found in literature which were pervasive in the period of the Joseon Dynasty (the period of Ming and Qing), it corresponds with Lee Jema's view that medical men in the Song, Yuan, and Ming Dynasties disclosed half of the prescriptions for Tae-eum person by studying these texts more.

• 동국한의학연구소논문집
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• 제6권1호
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• pp.205-229
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• 1997

금원사대가(金元四大家) 중의 한 사람인 주진형(朱震亨)은 주화론(主火論)의 영향을 받았지만 독창적인 "상화론(相火論)"과 "음부족이양유여(陰不足而陽有餘)"하다는 견해를 밝히면서 보음정이억상화(補陰精而抑相火)를 위주로한 치법(治法)을 제창하여 후대(後代)에 "자음파(滋陰派)"라고 불리운다. 이러한 단계(丹溪)의 의학사상(醫學思想)과 한방부인과학(韓方婦人科學)과 관련된 이론을 개괄하여 단계(丹溪)의 이론과 처방이 우리나라 한방(韓方) 부인과학(婦人科學)의 발전과정에 미친 영향을 고찰하였다. 그 결과 첫째, 단계(丹溪)의 증치사상(證治思想)의 특징은 거습담(祛濕痰), 조기(調氣), 자음청열(滋陰淸熱)의 치법(治法) 운용(運用)과 금욕적(禁慾的) 섭생(攝生)을 통한 양생론(養生論)이었으며, 둘째로 단계(丹溪)의 이론(理論)과 처방(處方)들은 <의방류취(醫方類聚)>와 <동의보감(東醫寶鑑)>에서 <단계심법(丹溪心法)>과 <단계심법부여(丹溪心法附餘)>의 내용을 대폭 수용함으로써 우리나라 한방부인과학(韓方婦人科學) 이론(理論)의 주요한 부분을 형성하는 계기가 되었으며, 셋째로, 부인과질환과 관련하여 월경병(月經病)에 조기(調氣) 및 거습담(祛濕痰)을, 불임증(不姙症)에는 월경불조(月經不調)와의 관련성(關聯性)은 물론 체형(體型) 체질별(體質別) 병기(病機)와 치법(治法)을 구분하였으며, "산전당청열양혈(産前當淸熱養血)" 이론에 의한 황금(黃芩) 백출(白朮)을 위주로 한 안태론(安胎論), "종담론치(從痰論治)"한 악조치법(惡阻治法), 난산예방(難産豫防), 산후(産後)의 "대보기혈(大補氣血)"등의 이론을 제시하여 단계(丹溪)의 학술사상이 우리나라 한방부인과학에 미친 영향은 많았던 것으로 사료된다.

• The Korean Journal of Physiology and Pharmacology
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• 제6권6호
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• pp.293-297
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• 2002

The role of 5-hydroxytryptamine $(5-HT)_1A$ receptor activity in prenatal ischemia was studied, by injecting 8-hydroxy-dipropylaminotetraline (8-OH-DPAT; $50{\mu}g/kg,$ s.c.), a $5-HT_1A$ agonist on gestation day 17, and 30 min later inducing transient ischemia by ligating the uterine vessels for 30 min. On postnatal day 95, rats that had experienced prenatal ischemia showed impaired motor coordination and reduced concentration of 5-HT in the cerebellum compared with Sham-operated controls. In addition, they showed increased $5-HT_1A$ receptor densities in the cerebral cortex. Pretreatment with 8-OH-DPAT ameliorated the behavioral and neurochemical sequelae measured in the present study. The results suggest that $5-HT_1A$ receptors protect the brain from ischemic insult and/or facilitate recovery after prenatally experienced ischemia.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2009년도 춘계 종합학술대회 논문집
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• pp.221-226
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• 2009

중국 MMORPG 게임에서 용의 캐릭터 디자인은 서양 게임의 용 캐릭터 영향을 받아 정체성이 결여 되어 있다. 서양 용 이미지가 너무 강해서 중국인들이 게임에서 그 용의 이미지를 받아 들이기에는 이질감이 너무 크다. 이러한 이유로 인해 중국전통 용의 디자인을 게임에 표현할 용 캐릭터디자인 분석이 필요하다. 우선 문화적 측면과 디자인적 측면을 고려하여 스타일 표현 특징을 설명하고 현재 MMORPG 게임에서 용 캐릭터로 사용되고 있는 용의 표현 분석을 통해 그 차이성을 살펴보고, 또한 동서양 융합을 모색할 수 있는 방향을 제안하고자 한다. 이를 위해 동양을 대표하는 중국 명대(明代)의 용과 서양 중세의 용의 비교 분석을 통해 용합하고 MMORPG에서 중국 게임 콘텐츠 디자인에 응용 가능한 용 캐릭터 프로토타입을 제작하고자 한다.

• Journal of Ginseng Research
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• 제46권2호
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• pp.175-182
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• 2022

Coronavirus disease 2019 (COVID-19) not only targets the respiratory system but also triggers a cytokine storm and a series of complications, such as gastrointestinal problems, acute kidney injury, and myocardial ischemia. The use of natural products has been utilized to ease the symptoms of COVID-19, and in some cases, to strengthen the immune system against COVID-19. Natural products are readily available and have been regularly consumed for various health benefits. COVID-19 has been reported to be associated with the risk of thromboembolism and deep vein thrombosis. These thrombotic complications often affects mortality and morbidity. Panax ginseng, which has been widely consumed for its various health benefits has also been reported for its therapeutic effects against cardiovascular disease, thrombosis and platelet aggregation. In this review, we propose that P. ginseng can be consumed as a supplementation against the various associated complications of COVID-19, especially against thrombosis. We utilized the network pharmacology approach to validate the potential therapeutic properties of P. ginseng against COVID-19 mediated thrombosis, the coagulation pathway and platelet aggregation. Additionally, we aimed to investigate the roles of P. ginseng against COVID-19 with the involvement of platelet-leukocyte aggregates in relation to immunity-related responses in COVID-19.

• 한국의상디자인학회지
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• 제16권2호
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• pp.101-109
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• 2014

Bangryeong generally means rectangular collars at present. However, it is estimated that there would be Bangryeong in different shapes besides rectangular shape in ancient times, but there is no accurate evidence. The dispute on the shape of Bangryeong started with the records in Yegi(禮記) and Simui written during Zhou period, China, the oldest records on Bangryeong. However, there are no remains or paintings(pictorial data) accurately proving the different shapes of Bangryeong. While the new shape of Gokgeop(collar of Simui) was mentioned by Zhu Xi during Song period, it was not accurately verified. There are almost no literature, excavated objects or pictorial data on the shapes of Bangryeong which are not definitely identified. The shape of Bangryeong is identified to a certain extent by objects excavated or pictorial data during Yuan and Ming period. There will be definite reasons why Zhou Xibao and Hua Mei, the scholars in China, the y-shaped collar rolled on the chest among the objects excavated during Warring States Period as Bangryeong or Guryeong. Thus, this paper investigated the notes and description in Yegijeongui(禮記正義) and the records and notes during the Han period which are mentioned most frequently except Yegi among the records on Bangryeong. Accordingly, this paper identified that there are different shapes of Bangryeong except rectangular shape during the Han period. It is estimated that Bangyeong at that time had symmetric collars, the collars of Jikryeong which are not overlapped. The collar section after the neck section was straight. It was also said that Bangyeong was women's clothing. In other words, Bangyeong in the Han period suggests that the collar of Jikryeong was Bangryeong. As discussed above, Bangryeong has the long history and different meanings by period. However, it is very difficult to accurately define Bangryeong because there are almost no records on it. Nevertheless, Bangryeong will be discussed more in further study.

• 한방안이비인후피부과학회지
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• 제12권1호
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• pp.179-214
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• 1999

The result were as follows: 1. Yu Wan So(劉完素) regarded the cause of surgical disease as the heat(熱). He used the three method to drain(疏通), promoting pus drainage(托裏) and the balance between ying-energy(營氣) and wei-energy(衛氣). 2. Jang Jong Jeung(張從正) only refered to medicines without entire theory. 3. Lee Dong Won(李東垣) regarded the cause of surgical disease as the greasy diet(膏梁厚味), damp air(濕氣), wetness heat(濕熱). For each treatment he used the method of Yu Wan So's treatment and emphasized the balance between ying-energy(營氣) and wei-energy(衛氣), stomach energy(胃氣). 4. Ju Jin Heung(朱震亨) distinguished the cause of surgical disease from enternal(內), external(外) and channel(經). For each treatment he used the method to drain(疏通), promoting pus drainage(托裏) and the balance between ying-energy(營氣) and wei-energy(衛氣). The first stage used the clearing away heat and toxic materials(淸熱解毒) and the last stage used the invigoration and dispersion(補托). 5. Yu Wan So(劉完素) used to be very busy of Moschus(麝香), Alumen(白礬), Olibanum(乳香), Coptidis Rhizoma(黃連), Minium(黃丹) and Scutel1ariae Radix(黃芩) In classification of the medical action, great part of the medicine are activating blood circulation to dissipate blood stasis(活血祛瘀), clearing away heat and toxic materials( 淸熱解毒) and external application(外用). 6. Jang Jong Jeung(張從正) used to be very busy of Olibanum(乳香), Angelicae Gigantis Radix(當歸), Minium(黃丹), Myrrha(沒藥), Calomelas(輕粉), Rhei Radix Et Rhizoma(大黃) and Phellodendri Cortex(黃柏). In classification of the medical action, great part of the medicine arc activating blood circulation to dissipate blood stasis(活血祛瘀), clearing away heat and toxic materials(淸熱解毒) and diverged wind-cold evil(發散風寒). 7. Lee Dong Won(李東垣) used to be very busy of Forsythiae Fructus(連翹), Scuteliariae Radix(黃芩), Angelicae Gigantis Radix(當歸). Astragali Radix(황기), Glycyrrhizae Radix(炙甘草), Bupleuri Radix(紫胡), Phellodendri Cortcx(黃柏), and Coptidis Rhizoma(黃連). In classification of the medical action, great part of the medicine are activating blood circulation to dissipate blood stasis(活血祛瘀), regulating vital energy(理氣) and clearing away heat and toxic materials(淸熱解毒). 8. Ju Jin Heung(朱震亨) used to be very busy of Glycyrrhizae Radix(甘草), Astragali Radix(황기), Angelicae Gigantis Radix(當歸), Phellodendri Cortex(黃柏), Scutellariae Radix(黃芩), Ginseng Radix(人蔘), Qlibanum(乳香). In classification of the medical action, great part of the medicine are clearing away heat and toxic materiaIs(淸熱解毒), activating blood circulation to dissipate blood stasis(活血祛瘀) and diverged wind-cold evil(發散風寒).

• Korean Journal of Acupuncture
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• 제31권1호
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• pp.40-47
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• 2014

Objectives : Postural instability and gait difficulty(PIGD) can develop in all Parkinson's disease patients, especially late in the disease course, but does not respond well to conventional dopamine treatment. This study aimed to report three cases of PIGD in Parkinson's disease patients treated with Korean and Western medicine treatment. Methods : We used acupuncture, bee venom acupuncture, herbal medicine and moxibustion to treat patients during hospitalization. They continued Western medication and received rehabilitation treatment. We observed the changes of PIGD using the Unified Parkinson's Disease Rating Scale(UPDRS). Results : After treatment, PIGD symptoms improved and UPDRS scores were decreased. Especially, scores of falling, walking, gait and postural stability subsections related with PIGD were decreased. In addition, general conditions of patients were improved. Conclusions : This study suggests that Korean medicine treatment could be effective in the treatment of PIGD in Parkinson's disease patients.