• Title/Summary/Keyword: Leaflet

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Effect of an Educational Intervention on Knowledge of Human Papillomavirus Vaccination among Pre-University Students in Malaysia

  • Kwang, Ng Beng;Mahayudin, Tasneem;Yien, Hii Ling;Abdul Karim, Abdul Kadir;Teik, Chew Kah;Shan, Lim Pei
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.1
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    • pp.267-274
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    • 2016
  • Background: Cervical cancer is the fourth most common cancer among women worldwide. Studies evaluating the effect of health education on knowledge and perception of cervical cancer have generated conflicting results. Thus, this study aimed to evaluate the effect of educational intervention towards knowledge of HPV vacccination for cervical cancer prevention among pre-university students in Malaysia. Materials and Methods: This was an experimental before and after study performed between October 2014 and March 2015. Five hundred and eighty students were randomly assigned into intervention and control groups. All were required to complete both pre-intervention and post-intervention questionnaires. Those in the intervention group were given an information leaflet to read before answering the post-intervention questionnaire. Results: Almost half (48.3%) of the students had poor knowledge, with a score less than 5, and only 51 (8.8%) exhibited good knowledge, with a score of 11 and above. After educational intervention, the number of students with poor knowledge was reduced to 177 (29.3%) and the number of students who exhibited good knowledge increased to 148 (25.5%). Students from the intervention group demonstrated significant higher total scores in knowledge regarding 'HPV infection and cervical cancer' (p=0.000) and 'HPV vaccination and cervical cancer prevention' (p=0.000) during post-intervention as compared to the control group. Conclusions: Knowledge on HPV infection and vaccination is low among pre-university students. Educational intervention in the form of information leaflets appears effective in creating awareness and improving knowledge.

Composition of Optimal Nutrient Solution for Single-stemmed Rose 'Red velvet' in a Closed Aeroponic System

  • Kang Mu Jang;Lee Joo Hyun;Lee Yong-Beom
    • Journal of Bio-Environment Control
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    • v.14 no.3
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    • pp.174-181
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    • 2005
  • Experiments were carried out to develop an optimal nutrient solution for the single-stemmed rose (Rosa hybrida L.) 'Red velvet' in a closed aeroponic system. Plants were grown in 1/3, 1/2, 1, or 3/2 strength of the nutrient solution of National Horticultural Research Station in Japan (NHRS). Significantly less changes of pH and EC ($dS{\cdot}m^{-1}$) in the drainage were observed in 1/2 strength treatment as compared to other treatments. The $NO_3-N$, K, Ca, and Mg concentrations in the drainage solution of 1/2 strength treatment were maintained at optimal levels. These results indicated that the rose uptakes of both nutrients and water was more stable than those in other concentration. The concentration of macronutrients in nutrient solution were adjusted based on the ratio of nutrient:water (n/w) taken up by plants grown in the 1/2 strength solution. The composition of the new solution (classified the University of Seoul (UOS) solution) was as follow; $NO_3-N$ 8.8, $NH_4-N$ 0.67, P 2.0, K 4.8, Ca 4.0, Mg 2.0 $me{\cdot}L^{-1}$. To further evaluate new solution on crop growth, the rose 'Red Velvet' was grown again in l/2, 1, and 2 strength UOS solution to compare with 1.0 strength PBG (proefstion voor bloemisterij en glasgroenpe) solution. Overall the plant growth, including the stem length and number of five-leaflet leaves was higher in 1.0 strength of UOS solution than other treatments. Results presented in this study indicate that the nutrients in the UOS solution are well balanced for the single-stemmed rose in the closed aeroponic system.

The relation of the bioprosthetic valve failure to its calcification (조직판막의 실패와 석회화에 관한 연구)

  • 홍유선
    • Journal of Chest Surgery
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    • v.22 no.6
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    • pp.1001-1012
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    • 1989
  • In 1968, Carpentier and his associates introduced glutaraldehyde as a compound for preparing cardiac tissue valve, and this technique has provided a considerably more suitable and durable tissue valve substitute. To increase further durability of valve tissue, Reis and his colleagues designed a flexible stent to reduce the stress on the heterogeneous tissue valve mounted. However with the advent of more innovative mechanical valve currently, many bioprosthetic valves are being substituted by mechanical valves at our department of cardiothoracic surgery because of bioprosthetic valve failure. Main cause of bioprosthetic valves failure were calcification or/and tear of tissue valves. The purpose of this retrospective study is to clarify the relationship between the patients clinical profile during implantation of tissue valves and pathologic features of the failed bioprosthetic valve. From March, 1982 through June, 1988, 53 bioprosthetic heart valves that had been ex-planted from 45 patients at the department of cardiac surgery of Yonsei University Hospital were subjected to this study. The patients were 10 to 65 year-old [mean age: 30.3 yr] with 17 males and 28 females. Re-replacements of prosthetic valves were carried out twenty nine in mitral position, eight in aortic position and eight in both aortic and mitral position simultaneously. The grading and location for calcification of valves were verified by radiograms. The calcification of the explanted valves leaflets was graded from 0 to 4 plus according to Cipriano and associates method. The types of tear and perforation of leaflet were classified into four types as Ishihara has adopted initially in 1981. In younger age group under thirty three years, explanted tissue valves were significantly more affected in terms of grades of severity of valve calcification as compared with older age group [p < 0.035]. Valve calcification appeared more severe in male as compared to female [p< 0.002]. Ionescu-Shiley bovine pericardial bioprosthetic valves showed more severe calcification than Hancock porcine tissue valves [p< 0.035]. Calcium deposit was found very prevalent at the area of commissural attachment [86 % of all]. Type I of valve rupture was shown to be related with simultaneous calcification. However, the relation of explanted valve position, duration of implanted prosthetic valve, atrial fibrillation and anticoagulant therapy to the severity of bioprosthetic valve calcification were not significantly clear statistically [p > 0.05].

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Animal Experiment and Blood Biocompatibility Study of Polymer Valve (고분자판막의 동물실험 및 생체내 혈액적합성 연구)

  • 김상현;홍유선
    • Journal of Chest Surgery
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    • v.30 no.4
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    • pp.357-362
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    • 1997
  • In vivo testings of the monoleaflet polymer valve were performed in seven dogs to prove its blood biocompatibility. The monoleaflet polymer valve used in this study was developed for short-term usage n the ventricular assist device. The frame and leaflet of the polymer valve were made of polyurethane. The inter-aortic valved conduit were implanted in four dogs and the ventriculo-atrial valved conduit was implanted in one dog. The ventricular assist devices with polymer valve were implanted in two dogs. The longest survival was 20 days. Main causes of death were bleeding and infection. To examine the blood compatibility, each blood sample was collected and RBC, WBC, hematocrit, hemoglobin, platelet and lactic acid dehydrogenase were analyzed. These studies thus far demonstrated that, with further development, a reliable and inexpensive polymer valve will be used in the ventricular assist device as short term usage.

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STRUCTURAL PERTURBATIONS INDUCED BY PHOTODYNAMIC ACTION OF PORPHYRIN AGGREGATES ON PLASMA MEMBRANE AND MICROSOMES OF GLIOBLASTOMA CELLS

  • Sreentvasan, Rajesh;Joshi, Preeti G.;Joshi, Nanda B.
    • Journal of Photoscience
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    • v.4 no.2
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    • pp.41-48
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    • 1997
  • The plasma membrane and microsomes, isolated from the cells treated with hematoporphyrm derivative (HpD) for 1 and 24 h, accumulated the aggregated porphyrin. The quantity of aggregated porphyrin was same in the plasma membrane and microsomes after isolating them from cells treated with HpD for 1 h whereas the microsomes accumulated higher quantity of aggregated porphyrin when cells were treated with HpD for 24 h. Photodynamic action of aggregated porphyrin on plasma membrane and microsomes was investigated using lipid specific fluorescent probes: 1,6-diphenyl-1,3,5-hexatrine (DPH) and 1-(4-trimethylammonium), 6-diphenyl-1,3,5-hexatrine(TMA-DPH). The time dependent anisotropy of these probes in the membranes was measured and the decay of anisotropy was analyzed using wobbling in cone model. Upon irradiation both the plasma membrane and the microsomes showed an increase in the limiting anis~)tropy and order parameter and a decrease in the cone angle of the lipid probes. The increase in the limiting anisotropy was pronounced in membranes isolated from the cells treated with HpD for 24 h. Photoinduced change in the limiting anisotropy was dependent on the duration of incubation of cells with HpD before isolating the membranes. In both the membranes. the membrane core was affected more as compared to the outer leaflet. In addition to the structural changes, a decrease in Na$^+$-K$^+$-ATPase and NADPH cyt c reductase activity was also observed upon irradiation of HpD treated cells. Inhibition in NADPH cyt c reductase was more when cells were treated with HpD for 24 h, however, Na$^+$-K$^+$-ATPase activity did not depend on the duration of the treatment of cells with HpD before irradiation. Our results suggest that the extent of photoinduced perturbations in the membranes varies as a function of duration of the treatment of cells with HpD and the membrane core is more susceptible to the photodynamic action of aggregated porphyrin.

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Congenital Polyvalvular Disease; Report of A Case (선천성 다발성 판막질환 1예 보고)

  • 김정원;민경석;윤태진;서동만;윤소영;김영휘;고재곤;박인숙;김규래
    • Journal of Chest Surgery
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    • v.34 no.8
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    • pp.626-629
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    • 2001
  • Congenital polyvalvular disease is a connective tissue disorder affecting more than one heart valve with variable involvement of the entire valvular and subvalvular apparatus. It is frequently associated with the Trisomy 18 and trisomy 13-15 or ventricular septal defect and patent ductus arteriosus. We present an isolated case of congenital polyvalvular disease in a new born baby with a review of the pertinent literatures, which has not been described in Korea. The mass was discovered as a right atrial mass in the prenatal ultrasonography and it was thought to be either a hematoma or a myxoma in the preoperative echocardiography. Microscopic examination of the surgically resected mass showed irregular thickening, nodulation, and additional features of calcification and ossification in the valvular connective tissue on the body of anterior and septal leaflet of tricuspid valve. Congenital polyvalvular disease should be included in the differential diagnosis in cases showing valvular calcification or ossification in the fetal echocardiography.

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A Comparative Study on Fashion Design Education in Europe and Korea -Focus on the Educational Cases in the UK, France, Italy and Korea- (유럽과 한국의 패션디자인 교육에 관한 비교연구 -영국, 프랑스, 이태리, 한국의 교육사례를 중심으로-)

  • Choi, Kyung-Hee
    • Journal of the Korean Society of Clothing and Textiles
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    • v.35 no.10
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    • pp.1199-1214
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    • 2011
  • This study suggests the direction of fashion design education suitable for Korea by comparing the fashion design educational systems and the curricula of the main fashion institutions in Europe and those of some universities in Korea. For this, 6 fashion schools in UK, France and Italy and 12 four-year-course universities in Korea were sellected. At first, the educational systems of the nations above and the information about the selected institutions were examined through literature reviews. Then, case studies were performed about the curricula and the other characteristics of the selected fashion design courses by each website or leaflet as well as additional interviews with their course directors or graduates. The results of this study are as follow: First, Korean fashion design education system needs to be specialized and subdivided with a curriculum centered on fashion design. Second, a foundation course needs to be developed to raise a broad and creative approach for design as well as to discover each student's aptitude. Third, the curricula about design process and research methodology need to raise a problem-solving individual of ability. Fourth, a project-based fashion design education is required by a specialized education as well as multi-disciplinary programs. Fifth, an industry- related and market-based fashion design education is asked through internships, professional teaching staff, industry-sponsored projects, seminars and professional design critics. Sixth, English and technology needs to be added to the curricula to develop global professionals. Finally, a cultural fashion design education based on Korean identity is required to develop the Korean fashion industry into a higher value-added business.

Inheritance of Agronomic Traits and Their Interrelationship in Mungbean(Vigna radiata(L.) Wilczek)

  • Sriphadet, Sukhumaporn;Lambrides, Christopher J.;Srinives, Peerasak
    • Journal of Crop Science and Biotechnology
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    • v.10 no.4
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    • pp.249-256
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    • 2007
  • A study was conducted to observe the variation and inheritance of agronomic traits and their interrelationship in mungbean. The objective of the study was to compare agronomic traits and hardseed percentage of 268 recombinant inbred lines(RILs) developed from the cross between wild Vigna subspecies sublobata "ACC 41" with the mungbean cultivar "Berken". The RIL population and their parents were evaluated under controlled conditions in a glass house at the University of Queensland, Brisbane, Australia. The results showed significant differences among the RILs and among the parents in all traits under study. Berken had a longer flowering date and a higher seed weight per plant, but less total leaf number and pod number per plant than ACC 41. A germination test between papers revealed that ACC 41 was 100% hard-seeded and did not germinate at all, while Berken germinated up to 100%. Their RILs distributed well between 0 to 100% hardseed. Upon scarification, all hardseed germinated within seven days. Narrowsense heritability estimates of total leave number, hardseedness, pod length, and pod width were highly heritable at 89.9, 98.9, 93.7, and 93.2%, respectively. The heritability of seed weight per plant and number of seeds per plant were lower at 63.1 and 58.4%, respectively. Seed weight per plant showed positive transgressive segregation when compared with ACC 41 and a positive correlation with 100 seed weight. While the number of seeds per pod showed a negative transgressive segregation when compared with Berken and a negative correlation with pod length and pod width. The RILs gave a 1:1 segregation ratio in leaflet shape, growth habit, and growth pattern, indicating that these traits were controlled by a single dominant gene.

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The Effect of Compliance Structures Near the Mechanical Heart Valve on Valve Surface Erosion (기계식 인공 판막 주위의 유연성 구조가 표면 괴식에 미치는 영향)

  • Lee, Hwan-Sung;Hwang, Sung-Won;Sun, Kyung
    • Journal of Biomedical Engineering Research
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    • v.23 no.4
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    • pp.309-315
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    • 2002
  • Since the discovery, in the 1980s, of erosion-pit-induced fractures in implanted mechanical heart valves. cavitation on the surface of mechanical heart valves has been widely studied as a possible cause of pitting. Several factors, including peak dp/dt of the ventricular pressure. maximum closing velocity of the leaflet, and squeeze flow. have been studied as indices of the cavitation threshold. In the present study. cavitation erosion on the surface of a mechanical valve was examined by focusing on squeeze flow and the water hammer phenomenon during the closing period of the valve. In this study, we measures pressure wave forms near a valve and closing velocities of a disk, which were placed in a holder with and without compliance. In case of all holders, pressure drop of below vapor pressure expect at near the surface disk. It was also found that the closing velocity of the disk increased and that cavitation erosion was enhanced too. These results suggest that disk closing velocity during the closing phase has signifiant effects on pitting erosion.

Preparation and Characterization of Mullite Whiskers (뮬라이트 휘스커의 제조와 특성)

  • Lee, Hong-Lim;Shim, Il-Yong;Kang, Jong-Bong
    • Journal of the Korean Ceramic Society
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    • v.41 no.1
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    • pp.51-56
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    • 2004
  • Mullite whiskers were synthesized using $Al(OH)_3$, amorphous $SiO_2$ and $AIF_3$ as starting materials by a vapor-solid reaction at relatively low temperature of $1100^{\circ}C$. Leaflet Fluorotopaz was observed for the specimen heat-treated at $800^{\circ}C$. Fluorotopaz was decomposed at $1000^{\circ}C$ and only mullite phase was observed for the specimen sintered at $1100^{\circ}C$ and above. It was found that the synthesized mullite at $1200^{\circ}C$ had grown to [001] direction and side planes were the {110}. The distance of (110} plane was $5.34^{\AA}C$. The amounts of $Al_2O_3$ in mullite was 73.56(1.39)wt%.