• Korean Journal of Computational Design and Engineering
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• v.9 no.4
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• pp.387-396
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• 2004

In order to keep and increase a competitive potential, industrial enterprises have to reduce their costs for product development as well as shorten lead time in product development processes. Moreover they have to respond to market factors and conditions such as increasing demands for functionality and individuality of products, short product life cycles, high pressure on prices and time to market. The improved functional requirement in connection with high time and cost pressure lead to high risk in product development. Technological fine improvements in connection with high time and cost pressure lead to high development risk. To cope with these challenges many enterprises have to collaborate globally. The collaborative engineering in product development is aimed to create distributed collaborative corporations and to facilitate the management of design conflicts. This paper provides a methodology for analyzing collaborative design process as well as the tools and the framework to support collaborative product development. The methodology can identify the interdependences among design tasks and teams. The tools and framework are implemented to facilitate the management of product development process.

• IE interfaces
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• v.21 no.4
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• pp.418-434
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• 2008

This paper studied issues in decision making on the production control policy of a cathode plate manufacturing process in zinc refining plant. The present production system has a long lead time from raw materials (aluminum plate) to products (cathode plate) due to many WIP inventories. Because WIP inventories are stocked at each process and moved from one place to another frequently, they are the main cause of inefficiency in the process. In this paper, to solve this problem, several production control policies have been identified and studied. Several simulation models are used to compare the performances of these production control policies. The output lead time and WIP (Work In Process) of real production system are compared with those of simulation models. PUSH, CONWIP, DBR, KANBAN and CONWIP-DBR models have been used to simulate and review the optimized production control policy that achieves the target output quantities with decreased lead time and WIP. The simulation results of each production control policy show that CONWIP and CONWIP-DBR models are the good production control policy under the present production system. Especially in present production system, CONWIP with one parameter is easier control policy than CONWIP-DBR with two parameters. Therefore CONWIP has been selected as the best optimum production control policy. With CONWIP, lead time has been reduced by 97% (from 6,653 to 187 minute) and WIP has been reduced from 1,488 to 53, compared to the present system.

• Journal of the Korea Safety Management & Science
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• v.20 no.3
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• pp.11-19
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• 2018

This study suggests a model of production information system that can reduce manufacturing lead time and uniformize quality by using DNC S/W as a part of constructing production information management system in the industrial field of the existing marine engine block manufacturing companies. Under the effect of development of this system, the NC machine interface device can be installed in the control computer to obtain the quality information of the workpiece in real time so that the time to inspect the process quality and verify the product defect information can be reduced by more than 70%. In addition, the reliability of quality information has been improved and the external credibility has been improved. It took 30 minutes for operator to obtain, analyze and manage the quality information when the existing USB memory is used, but the communication between the NC controller computer and the NC controller in real time was completed to analyze the workpiece within 10 seconds.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.38 no.4
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• pp.109-116
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• 2015

This paper is concerned with the single vendor single buyer integrated production inventory problem. To make this problem more practical, space restriction and lead time proportional to lot size are considered. Since the space for the inventory is limited in most practical inventory system, the space restriction for the inventory of a vendor and a buyer is considered. As product's quantity to be manufactured by the vendor is increased, the lead time for the order is usually increased. Therefore, lead time for the product is proportional to the order quantity by the buyer. Demand is assumed to be stochastic and the continuous review inventory policy is used by the buyer. If the buyer places an order, then the vendor will start to manufacture products and the products will be transferred to the buyer with equal shipments many times. The mathematical formulation with space restriction for the inventory of a vendor and a buyer is suggested in this paper. This problem is constrained nonlinear integer programming problem. Order quantity, reorder points for the buyer, and the number of shipments are required to be determined. A Lagrangian relaxation approach, a popular solution method for constrained problem, is developed to find lower bound of this problem. Since a Lagrangian relaxation approach cannot guarantee the feasible solution, the solution method based on the Lagrangian relaxation approach is proposed to provide with a good feasible solution. Total costs by the proposed method are pretty close to those by the Lagrangian relaxation approach. Sensitivity analysis for space restriction for the vendor and the buyer is done to figure out the relationships between parameters.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.44 no.2
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• pp.140-152
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• 2021

During the shift from gasoline vehicles to electric ones, auto parts manufacturing companies have realized the importance of improvement in the manufacturing process that does not require any layout changes nor extra investments, while maintaining their current production rate. Due to these reasons, for the auto part manufacturing company, I-company, this study has developed the simulation model of the PUSH system to conduct a process analysis in terms of production rate, WIP level, and logistics work's utilization rate. In addition, this study compares the PUSH system with other three manufacturing systems -KANBAN, DBR, and CONWIP- to compare the performance of these production systems, while satisfying the company's target production rate. With respect to lead-time, the simulation results show that the improvement of 77.90% for the KANBAN system, 40.39% for the CONWIP system, and 69.81% for the DBR system compared to the PUSH system. In addition, with respect to WIP level, the experimental results demonstrate that the improvement of 77.91% for the KANBAN system, 40.41% for the CONWIP system, and 69.82% for the DBR system compared to the PUSH system. Since the KANBAN system has the largest impacts on the reduction of the lead-time and WIP level compared to other production systems, this study recommends the KANBAN system as the proper manufacturing system of the target company. This study also shows that the proper size of moving units is four and the priority allocation of bottleneck process methods improves the target company's WIP and lead-time. Based on the results of this study, the adoption of the KANBAN system will significantly improve the production process of the target company in terms of lead-time and WIP level.

• Journal of Environmental Health Sciences
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• v.19 no.4
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• pp.67-82
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• 1993

This study was performed to investigate the preventive effect of KDD against lead toxicity. KDD of 133, 266, 532 and 1,064 mg/kg were administered twice to the rats of Sprague-Dawley strain and then 300 mg/kg lead acetate was given to times, respectively. 1. The accumulation effects of KDD against to lead showed the changes of lead concentration by time variation. But, no statistical significance were showed on 8 and 10 weeks for kidney, spleen, 8 weeks for liver, and 4, 6 and 8 weeks for duodenum. In the femur, statistical significance existed during the whole experimental period. The relatively high concentration of lead detected in the feces of the experimental group means that KDD facilitated excretion of lead. 2. The histopathological effect of KDD against lead showed cytomegaly, karyomegaly, inclusion body, urinary cast and hemosiderin of kidney in the experimental group I (Pb 300 mg/kg). Recovery of KDD administrated group was inclined to increase by KDD concentration. But, spleen's histopathological recovery of KDD aginst to lead did not show as much as kidney. In conclusion, this study revealed the preventive effect of KDD against lead toxicity and its mechanism inferred to facilitate lead excretion in feces following hinderance of lead absorption in the gastric-intestine and organs.

• Journal of the Korea Society of Computer and Information
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• v.7 no.2
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• pp.196-204
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• 2002

This paper examines the price discovery role of the KOSPI 200 futures index for its cash index. It was used the intrady data for KOSPI 200 and futures index from July 1998 to June 2001. The existing Preceding study for KOSPI 200 futures index was used the data of early market installation, but this study is distinguished to use a recent data accompanied with the great volume of transaction and various investors. We established three hypothesis to examine whether there is the price discovery role in the KOPSI 200 futures index and the characteristics of that. First, to examine whether the lead-lag relation is induced by the infrequent trading of component stocks, observations are sorted by the size of the trading volume of cash index. In a low trading volume, the long lead time is reported and the short lead time in a high volume. It is explained that the infrequent trading effect have an influence on the price discovery role. Second, to examine whether the lead-lag relation is different under bad news and good news, observations are sorted by the sign and size of cash index returns. In a bad news the long lead time is reported and the short lead time in a good news. This is explained by the restriction of"short selling" of the cash index Third, we compared estimates of the lead and lag relationships on the expiration day with those on days prior to expiration using a minute-to-minute data. The futures-to-spot lead time on the expiration day was at least as long as other days Prior to expiration, suggesting that "expiration day effects" did not demonstrate a temporal character substantially different form earlier days. Thus, while arbitrage activity may be presumed to be the greatest at expiration, such arbitrage transactions were not sufficiently strong or Pervasive to alter the empirical price relationship for the entire day. for the entire day.

• Toxicological Research
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• v.25 no.4
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• pp.231-235
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• 2009

Trace lead detection for cyclic voltammetry (CV) and square-wave (SW) stripping voltammetry was performed using mercury immobilized onto a carbon nanotube electrode (HNPE). Using the characteristics of mercury and the catalytic carbon nanotube structure, a modified technique, the $0.45{\mu}g/l$ detection limit of lead ion was attained. The developed method can be applied to pond water, fish tissue, plant tissue, and in vivo direct assay.

• Bulletin of the Korean Chemical Society
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• v.15 no.5
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• pp.390-393
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• 1994

Details on the electrochemical formation of lead dioxide from aqueous plumbous ion are studied by measuring current-time behavior with potential step method at a rotating platinum electrode. A cubic law without induction period can be applied to the crystallization of lead dioxide in both acetate and nitrate media. In the course of the mechanistic study, the presence of a soluble intermediate during the nucleation step is clearly observed with a rotating ring-disk electrode. Decrease in the anodic ring current due to the reduction of soluble species formed during the anodic crystallization of lead dioxide at disk is detected.

• Applied Microscopy
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• v.17 no.2
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• pp.41-54
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• 1987

This experiment was performed to investigate the acute and chronic effects of lead on cerebral cortex. In acute treatment, mouse were injected with lead acetate at dose of 0.3 mmole/kg body weight, and in chronic treatment, mouse were supplied 0.03 M lead acetate sol. in the place of water. After treatment, mouse were sacrificed at time intervals of 24, 48, 72, and 96 hours in acute treatment and at time intervals of 4 weeks and 8 weeks in chronic treatment. In acute treatment, acetylcholinesterase activity is reduced at 72 hours and recovered at 96 hours in homogenate, and reduced at 24 hours and recovered at 72 hours in crude synaptosomes. In chronic treatment, acetylcholinesterase activity is increased in young mouse but reduced in mother mouse. Ultrastructural changes were composed of swelling of Golgi apparatus, nerve terminals with diminished synaptic vesicles, and vacuolated myeline lamellae of myelinated axon.