• Applied Microscopy
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• 제47권3호
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• pp.203-207
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• 2017

A homogeneous $KNbO_3$ (KN) phase was formed by sintering at $1,040^{\circ}C$ for 1 hour, without formation of the $K_2O$-deficient secondary phase even though suffering the minor loss of $K_2O$. KN liquid phase was formed during sintering and abnormal grain growth occurred in this specimen. The detailed microstructural observations on KN during sintering were carried out using high resolution transmission electron microscopy. The ledged structures were found at the KN grain boundary and the abnormal grain growth was performed by the lateral migration of these ledges in the presence of the liquid phase. The liquid pockets were found in the KN grains. They have various external shapes mainly due to the kinetic factors. They have atomically flat interfaces with some ledges with one atomic height. The slight deficient $K_2O$ by evaporation might somewhat reduce the melting point of KN from the reported at $1,058^{\circ}C$. The liquid pockets play an important role in supplying the liquid phase during the abnormal grain growth in the sintering process of KN ceramics.

• 대한소아치과학회지
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• 제26권1호
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• pp.38-43
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• 1999

치아전위는 비교적 드문 발육장애이다. 적절하게 차단치료된다면 예방이 가능할 뿐 아니라 이후의 교정과 수복과정이 보다 용이할 수 있다. 이를 위한 8-9세 경의 조기 임상검사가 이러한 발육장애의 인지를 위해 추천된다. 일단 전위가 일어난 경우에는, 부정교합을 교정하고 최상의 기능적, 심미적 결과를 얻기 위해 주의깊은 교정적 평가가 요구된다. 이상적인 결과를 얻기 위하여 두 치아를 원래의 위치로 환원시키는 치료가 요구되나, 완전전위되어 두 치아가 맹출되었다면 전위된 상태로 치아를 배열하여도 비교적 양호한 결과를 얻을 수 있었다.

• Journal of Korean Neurosurgical Society
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• 제42권5호
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• pp.367-370
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• 2007

Objective : There are numerous reports on the primary stabilizing effects of the different cervical cages for cervical radiculopathy. But, little is known about the subsidence which may be clinical problem postoperatively. The goal of this study is to evaluate subsidence of cage and investigate the correlation between radiologic subsidence and clinical outcome. Methods : To assess possible subsidence, the authors investigated clinical and radiological results of the one-hundred patients who underwent anterior cervical fusion by using $AMSLU^{TM}$ cage during the period between January 2003 and June 2005. Preoperative and postoperative lateral radiographs were measured for height of intervertebral disc space where cages were placed intervertebral disc space was measured by dividing the sum of anterior, posterior, and midpoint interbody distance by 3. Follow-up time was 6 to 12 months. Subsidence was defined as any change in at least one of our parameters of at least 3 mm. Results : Subsidence was found in 22 patients (22%). The mean value of subsidence was 2.21 mm, and mean subsidence rate was 22%. There were no cases of the clinical status deterioration during the follow-up period No posterior or anterior migration was observed. Conclusion : The phenomenon of subsidence is seen in substantial number of patients. Nevertheless, clinical and radiological results of the surgery were favorable. An excessive subsidence may result in hardware failure. Endplate preservation may enables us to control subsidence and reduce the number of complications.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1995년도 추계학술대회
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• pp.34-38
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• 1995

Using a 3-D finite element method (FEM), the biomechanical characteristics of a threaded truncated acetabular component and a porous coated hemispherical acetabular component were studied. The Von-Mises stress/strain patterns in the acetabulum reconstructed with these two different types of cementless acetabular cups were investigated. The geometry and dimensions of human hemi-pelvis used in the present shape modeling for finite element analysis were scanned with a 3-D laser scanner(TDS-9000, Cyberware, USA). The scanned data was numerically handled with a shape modelling software 'Pro-Engineer'. Using 19836, 16853 tetrahedral elements, respectively, the stress and displacement field of the acetabulum reconstructed with the two different types of the acetabular components were computed. While the hemi-sphere component was found to show a relatively similar stress/strain patterns to those in the normal hip, the results with the threaded cup showed a considerably different patterns from those in the normal condition. Several regions in cancellous bone near the threads and the edge of the truncated cup was found to be overstressed, especially in the superior-lateral part of the acetabulum. It was postulated that the excessive reaming-out of subchondral bone layer when the truncated cup was used can cause the presence of these overstressed regions of cancellous bone. This theoretical prediction for the implanted acetabulum appeared to consistent with the pathological observation of proximal/medial migration of the threaded truncated acetabular prostheses in the previous publications.

• 산업융합연구
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• 제17권4호
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• pp.39-43
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• 2019

마우스 배아 줄기 세포는 신경 세포 분화가 가능한 세포의 대안적인 공급원이 될 수 있으며 잠재적으로 신경계 질환의 치료에 유용하게 사용될 수있다. 우리는 배아 줄기 세포 (ESCs)가 신경 분화를 유도하도록 유도 될 수 있는지를 조사했다. 신경 세포 유도 후, mESC의 표현형이 뉴런의 형태학으로 변하였고, mESCs는 실험쥐 뇌의 측 뇌실로 주입되었다. 이식 된 세포는 뇌의 여러 부위로 이동하였고 중대뇌동맥 결찰에 의한 허혈성 뇌혈관 손상부위에 이식된 줄기세포군이 손상된 피질부위로 집중적으로 이동하여 손상복구 기전을 증가시켰다. mESCs의 뇌내 이식은 MCAO 쥐의 기능적 결손의 감각 및 운동 회복을 유의 적으로 향상시킨다. 이러한 데이터는 이식 된 mESC가 허혈성 미세 환경에서 생존, 이동 및 분화하고 쥐에서 뇌졸중 후 신경 기능 회복을 향상 시킨다는 것을 나타낸다. 따라서 우리는 mESC의 이식이 인간 신경계 손상 및 퇴행성 장애에 대한 강력한 이식 치료법을 제공 할 것으로 기대한다.

• 대한정형외과스포츠의학회지
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• 제1권2호
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• pp.124-130
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• 2002

목적:반월상연골변연부파열을반월상연골화살로고정하였으며그치료결과를분석하였다 .대상및방법: 반월상연골변연부파열25예로서내측이18예, 외측이6예, 양측이1예였다. 전예후방1/2 부위의파열이었으며, 각각의예마다화살을1개내지6개를삽입하였다. 전방십자인대동반파열이 14예( 56.0$\%$ )였다. 추시기간은평균3.4년이었다. 결과는이학적검사와수술후1 $\~$ 5년사이에1 $\~$ 2회시행한자기공명영상소견으로판정하였다. 결과:전예에서반월상연골파열의치유를얻었으나, 2예에서화살삽입선을따라종파열이발생하였고, 2예에서화살의피하이동으로동통을호소하였으며제거후쾌유되었다. 결론:화살이파열의치유에는효과적이었다. 다만나란히가깝게화살을많이삽입하면삽입구선을따라종파열이발생할가능성이있으며, 화살의피하이동도주의를요한다.

• 대한지리학회지
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• 제33권3호
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• pp.355-364
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• 1998

하천 합류점의 하노형상을 파악하고 하도형상에 영향을 미치는 요소를 조사하기 위해 소형 수로실험을 실시했다. 합류하는 두 수류리 모삔트가 동일하면 할류후 하도는 합류각도를 이분하는 방향으로 늘어서기 때문에 초기하도의 배열에 따라 하도의 측방이동이 일어난다. 그 결과 합류후 하도의 형상은 합류의 평면형태 즉 대칭형, 점이형. 비대칭형에 따라 달라진다. 합류에 기인하는 가장 특징적인 하도혈상으로 하상 세굴부를 들 수 있다. 급경사의 양벽으로 둘러싸인 합류점의 세굴부는 기본적으로 합류각도에 의해 지배된다. 하천합류는 전통적으로 협화적이라고 표현되어 왔지만 불협화적 합류도 빈번하게 발생한다. 합류의 불협화에는 합류하천의 유량비뿐만 아니라 유사농도비도 관여한다. 따라서 불협화를 일으키는 최대요소로는 두 비를 고려한 수면폭당 단위유량비를 들 수 있다.

• Advances in pediatric surgery
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• 제2권1호
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• pp.64-67
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• 1996

1세된 남아에서 세열낭종을 의심한 좌측 경부 종양이 수술을 시행한 결과 고형종양이였고, 조직검사상 이소성 흉선으로 판명되었다. 술후 초음파상 흉선은 정상적으로 있었고, 현재 환자의 면역기능은 아무 이상없이 정상으로 자라고 있다.

• 대한의용생체공학회:의공학회지
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• 제43권3호
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• pp.170-176
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• 2022

Cell separation from a heterogenous mixture sample is an essential process for downstream analysis in biological, chemical, and clinical applications. This study demonstrates an integrated hybrid device of the viscoelastic focusing in a straight rectangular channel and subsequent size-based separation using acoustophoresis to attain high efficiency and separation tunability. For particle pre-alignment in a viscoelastic fluid, the flow rate higher than 10 μl/min was required. Surface acoustic wave-based lateral migration of particles with different sizes (13 and 27 ㎛) was examined at various applied voltages and flow rate conditions. Therefore, the flow rate of 100 μl/min and the applied voltage of 20 V_pp can be used for size-based particle separation.

• Geomechanics and Engineering
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• 제29권1호
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• pp.91-97
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• 2022

The cohesive non-swelling soil (CNS) cushion technology has been widely applied in the subgrade and slope improvement at expansive soil regions. However, the mechanism of the inhibition effect of the CNS layer on expansive soil (ES) has not been fully understood. We performed four outdoor model tests to further understand the inhibition effect, including different kinds of upper layer and thickness, under the unidirectional seepage condition. The swelling deformation, soil pressure, and electrical resistivity were constantly monitored during the saturation process. It is found that when a CNS layer covered the ES layer, the swelling deformation and electrical resistivity of the ES layer decreased significantly, especially the upper part. The inhibition effect of the CNS layer increases with the increase of CNS thickness. The distribution of vertical and lateral soil pressure also changed with the covering of a CNS layer. The electrical resistivity can be an effective index to describe the swelling deformation of ES layer and analyze the inhibition effect of the CNS layer. Overall, the CNS deadweight and the ion migration are the major factors that inhibit the swelling deformation of expansive soil.