• 제목/요약/키워드: Latent Mean

검색결과 159건 처리시간 0.032초

Determination of Frequency of Epstein-Barr Virus in Non-Hodgkin Lymphomas Using EBV Latent Membrane Protein 1 (EBV-LMP1) Immunohistochemical Staining

  • Ishtiaq, Sheeba;Hassan, Usman;Mushtaq, Sajid;Akhtar, Noreen
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권6호
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    • pp.3963-3967
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    • 2013
  • Background: The presence of Epstein-Barr virus (EBV) in Non-Hodgkin's lymphoma can be identified by immunohistochemistry for detection of EBV latent membrane protein (LMP). The role of EBV as an etiologic agent in the development of non-Hodgkin lymphoma has been supported by detection of high levels of latent membrane protein 1 (LMP-1) expression in tumors. However, no study has been conducted in a Pakistani population up till now to determine the frequency of Epstein-Barr virus positivity. The objective of our study was to determine a value for non-Hodgkin lymphoma patients using EBV LMP-1 immunostaining in our institution. Materials and Methods: This study was carried out at the Department of Histopathology, Armed Forces Institute of Pathology (AFIP), Pakistan from December 2011 to December 2012. It was a cross sectional study. A total of 71 patients who were diagnosed with various subtypes of NHL after histological and EBV LMP-1 immunohistochemical evaluation were studied. Sampling technique was non-probability purposive. Statistical analysis was achieved using SPSS version 17.0. Mean and SD were calculated for quantitative variables like patient age. Frequencies and percentages were calculated for qualitative variables like subgroup of NHL, results outcome of IHC for EBV and gender distribution. Results: Mean age of the patients was $53.6{\pm}16$ years (Mean${\pm}$SD). A total of 50 (70.4%) were male and 21 (29.6%) were female. Some 9 (12.7%) out of 71 cases were positive for EBV-LMP-1 immunostaining, 2 (22.2%) follicular lymphoma cases, 1 (11.1%) case of T-cell lymphoblastic lymphoma, 4 (44.4%) cases of diffuse large B cell lymphomas, 1 (11.1%) mantle cell lymphoma and 1 (11.1%) angioimmunoblastic T cell lymphoma case. Conclusion: In our study, frequency of EBV in NHL is 12.7% and is mostly seen in diffuse large B cell lymphoma. This requires further evaluation to find out whether this positivity is due to co-infection or has a role in pathogenesis.

장애자녀 돌봄제공자의 웰니스 증진을 위한 융복합 돌봄역량 요인 연구 (A study on the factors of convergent caring competency for promotion of caregivers' wellness of disabled children)

  • 이유리;김남중
    • 디지털융복합연구
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    • 제14권2호
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    • pp.479-487
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    • 2016
  • 본 연구는 장애자녀 부모가 인식한 돌봄역량, 돌봄경험의 평가(돌봄부담, 돌봄만족), 자조집단지지의 수준이 자녀의 장애유형(정신장애, 신체장애)에 따라 차이가 있는지 탐색하는데 목적이 있다. 이를 위해 전국 장애자녀 부모 301명을 조사대상자로 하였고, 자녀의 장애유형에 따라 정신장애 유형 180명과 신체장애 유형 121명으로 구분하였다. 두 집단의 잠재평균분석을 위해 형태동일성 검증, 측정동일성 검증, 절편동일성 검증, 요인분산동일성 검증을 실시하였다. 연구결과 정신장애 자녀를 돌보는 부모 집단은 신체장애 자녀를 돌보는 부모 집단에 비해 자조집단지지와 돌봄부담이 더 높게 분석되었고, 반대로 신체장애 자녀를 돌보는 부모 집단은 정신장애 자녀를 돌보는 집단에 비해 돌봄만족과 돌봄역량이 더 높은 것으로 나타났다. 이러한 결과를 바탕으로 실천적 서비스 개입 방안을 제시하였다.

산후 2주 축약형 모유수유 적응 측정도구의 구성 타당도, 신뢰도와 측정 불변성 (Breastfeeding Adaptation Scale-Short Form for mothers at 2 weeks postpartum: construct validity, reliability, and measurement invariance)

  • 김선희
    • 여성건강간호학회지
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    • 제26권4호
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    • pp.326-335
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    • 2020
  • Purpose: This study was conducted to evaluate the construct validity, reliability, measurement invariance, and latent mean differences in the Breastfeeding Adaptation Scale-Short Form (BFAS-SF) for use with mothers at 2 weeks postpartum. Methods: This methodological study was designed to evaluate the validity, reliability, and measurement invariance of the BFAS-SF at 2 weeks postpartum, with data collected from 431 breastfeeding mothers. Confirmatory factor analysis and multi-group confirmatory factor analysis were conducted to assess the factor structure and the measurement invariance across employment status, delivery mode, parity, and previous breastfeeding experience, and the latent mean differences were then examined. Results: The goodness of fit of the six-factor model at 2 weeks postpartum was acceptable. Multi-group confirmatory factor analysis supported strict invariance of the BFAS-SF across employment status and delivery mode. Full configural invariance, full metric invariance, and partial scalar invariance across parity and full configural invariance and full metric invariance across previous breastfeeding experience were supported, respectively. The results for latent mean differences suggested that mothers who were employed showed significantly higher scores for breastfeeding confidence. Mothers who had a vaginal delivery showed significantly higher scores for sufficient breast milk and baby's feeding capability. Multiparous mothers showed significantly higher scores for baby's feeding capability and baby's satisfaction with breastfeeding. Conclusion: The validity and reliability of the BFAS-SF at 2 weeks postpartum are acceptable. It can be used to compare mean scores of breastfeeding adaptation according to employment status, delivery mode, and parity.

제주도 북부해역의 표면 열수지 해석 -1993년과 1994년 하계의 경우- (Surface Heat Budget of the Northern Sea of Cheju Island for June-August 1993 and 1994)

  • 김해동;양성기
    • 한국환경과학회지
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    • 제4권3호
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    • pp.197-206
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    • 1995
  • Surface heat balance of the northern sea of Cheju Island for summer in 1993 and 1994 is analyzed using the observation data obtained by Marine Research Institute, Cheju National University. Each flux elements at the sea surface is derived from the marine meteorological reports with application of an aerodynamical bulk method for the turbulent heat fluxes, and empirical formulae for the long-wave radiation heat fluxes. The flux divergence of oceanic heat transport and the rate of heat storage in the ocean are estimated as residual. The features of the surface heat balance are mainly decided by the solar radiation flux and the latent heat flux for 199B. But the Bowen Ratios were large for 1993. This means that the sensible heat fluxes were nearly equal to the latent heat fluxes for 1993. In this period, mean flux divergence of oceanic heat transport is about 130 W/$m^2$.

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평균-분산 모형을 이용한 화석에너지원 소비조합 구성에 관한 연구 (A Study on Construction of an Optimal Fossil Fuel Mix: A Portfolio-Based Approach)

  • 차경수
    • 자원ㆍ환경경제연구
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    • 제20권2호
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    • pp.335-356
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    • 2011
  • 본 연구에서는 Markowitz (1952)의 평균-분산 모형과 지배원리에 입각하여 원유, 석탄, 천연가스로 대표되는 화석에너지원의 최적 소비조합을 구축하려 하였다. 이를 위해 1달러당 열량으로 정의된 화석에너지원들의 편익변동을 동태은닉공통인자 모형을 이용하여 동행부분과 개별 에너지원의 특이적 수급상황에 기초한 변동으로 분해한 후, 그 결과에 기초하여 최적 화석에너지원의 최적 소비조합을 구성하였다. 분석결과, 평균-분산 모형에서 최적 소비조합을 의미하는 효율적 프론티어 선상의 소비조합들에서는 사회적으로 도달 가능한 최저 수준의 원유소비 비중을 유지하면서 석탄보다는 천연가스의 소비비중을 높여야 하는 것으로 나타났다. 이와 같은 결과는 현재 우리나라에서 추구하고 있는 원유 및 석탄의 소비비중 축소전략과도 일치하는 결과라 할 수 있으며, 원유소비의 비중축소가 화석에너지원의 소비로부터 얻을 수 있는 편익향상과 함께 편익변동에 따르는 경제활동의 불안정성을 축소시킬 수 있는 방법임을 지적하는 것이라 할 수 있다.

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잠재요인 모델 기반 영화 추천 시스템 (Movie Recommendation System based on Latent Factor Model)

  • ;김강철
    • 한국전자통신학회논문지
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    • 제16권1호
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    • pp.125-134
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    • 2021
  • 영화 산업의 빠른 발전으로 영화의 제작 수가 급격하게 증가하고 있으며, 영화 추천 시스템은 관객들의 과거 행동이나 영화 후기에 기반하여 관객들의 선호도를 예측하여 영화의 선택에 도움을 주고 있다. 본 논문은 평점의 평균과 편향의 보정을 이용하여 잠재요인 모델에 기반한 영화 추천 시스템을 제안한다. 특이값 분해 방법이 평점 매트릭스 분해에 사용되고, 통계 경사 하강법이 최소자승 손실 함수의 파라미터 최적합에 사용된다. 그리고 평균 제곱근 오차를 사용하여 제안한 시스템 성능을 평가한다. Surprise 패키지를 이용하여 제안한 시스템을 구현 하였으며, 모의실험 결과는 평균 제곱근 오차가 0.671이며, 다른 논문에서 방법에 비하여 좋은 성능을 가진다는 것을 확인하였다.

중학생의 진로성숙도와 성취 목표, 학습 태도 및 학업성취도 실증적 고찰 : 교과연계 진로교육 경험을 중심으로 (An Empirical Study on Career Maturity, Achievement Goal, Learning Attitude and Academic Achievement of Middle School Students : Focused on Subjects-Related Career Education)

  • 함승연
    • 수산해양교육연구
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    • 제24권5호
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    • pp.616-626
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    • 2012
  • The purpose of this study is to verify career maturity, achievement goal, learning attitude and academic achievement relation with subjects-related career education of middle school students. To achieve these aims, this study used SELS(Seoul education longitudinal study) of Seoul Education Research & Information Institute. Also, analysis as well as descriptive statistics calculation on average, deviation, skewness and kurtosis of variable factor and calculated characteristic item and degree of reliability(Cronbach ${\alpha}$). For goodness of fit test, this study used TLI(Tucker-Lewis index) and RMSEA(Root mean square error of approximation). To achieve the ultimate objects, this study used LMA(latent mean analysis) for analysis of difference career maturity, achievement goal, learning attitude and academic achievement relation with subjects-related career education in middle school students. The results are as follows. First, experience relation with subjects-related career education were influenced on career maturity with career cognition. Second, experience relation with subjects-related career education were influenced on achievement goal, learning attitude, and larger than career maturity and academic achievement. Third, experience relation with subjects-related career education were influenced on middle school students more than inexperienced relation with subjects-related career education.

The Breast Feeding Adaptation Scale-Short Form: Development and Testing of Its Psychometric Properties and Measurement Invariance

  • Kim, Sun-Hee
    • Child Health Nursing Research
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    • 제25권3호
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    • pp.333-343
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    • 2019
  • Purpose: This study sought to develop the Breastfeeding Adaptation Scale-Short Form (BFAS-SF) for use at 4 weeks postpartum, to test its validity and reliability, and to examine its measurement invariance. The latent mean score of the BFAS-SF across multiple groups was also compared. Methods: This methodological research study was conducted to develop a short form of the BFAS and to test its psychometric properties and measurement invariance. Data were collected twice for measurement invariance testing. The sample included 431 and 272 breastfeeding mothers at 2 weeks and 4 weeks postpartum, respectively. Results: Confirmatory factor analysis supported six dimensions of the BFAS-SF at 4 weeks postpartum. Multi-group confirmatory factor analysis revealed evidence for invariance of the BFAS-SF according to employment status, parity, delivery mode, and the postpartum period. There were statistically significant latent mean differences. Mothers who were unemployed and who had a vaginal delivery showed significantly higher scores for breastfeeding confidence, sufficient breast milk, and baby's satisfaction with breastfeeding. Conclusion: The BFAS-SF is valid, reliable, and an appropriate instrument for assessing mothers' breastfeeding adaptation. It can be used to compare mean scores according to employment status and delivery mode.

예비 교사들을 대상으로 한 과학적 자기 효능감 척도 타당도 검증과 배경 변인별 잠재평균분석 (Validation of Science Self-Efficacy Scale for Pre-Service Teachers and Latent Mean Analysis According to Background Variable)

  • 이현동
    • 한국초등과학교육학회지:초등과학교육
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    • 제41권1호
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    • pp.65-78
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    • 2022
  • 이 연구의 목적은 예비 교사들을 대상으로 과학적 자기 효능감 척도의 타당도 검증과 배경 변인에 따른 잠재평균분석을 통해 예비 교사 교육에서의 시사점을 도출하는 것이다. 이를 위하여 187명의 예비 교사들을 대상으로 과학적 자기 효능감 척도(Tark, 2011)를 활용한 사전 검사를 진행하였다. 그리고 탐색적 요인분석을 통해 도출한 결과를 바탕으로 전문가 협의회를 실시하여 문항을 보완한 후 354명의 예비 교사들에게 본 검사를 실시하였으며 탐색적 요인분석과 확인적 요인분석을 실시하였다. 분석 결과 사전 검사에는 과학적 자기 효능감 척도에 예비 교사들은 3개 요인으로 응답하였으나 2개 문항의 타당도가 낮게 나타났다. 수정한 척도를 활용하여 본 검사를 실시한 결과 29개 문항이 의도한 3개 요인에 적재되었음을 확인하였으며 각 요인별 신뢰도는 .882~.886으로 나타났다. 예비 교사들의 배경 변인에 따른 잠재평균분석을 실시하여 효과 크기를 도출한 결과, 성별에 따라서는 자기조절효능감(Cohen's d > .5)은 여성이 자신감(Cohen's d > .3)은 남성이 유의미하게 높은 결과를 보여주었다. 진로 계열과 과학에 대한 선호도 변인에서는 과제곤란도선호 요인과 자기조절효능감 요인에서 자연(이공)계열, 그리고 과학에 긍정적 선호를 선택한 예비 교사가 유의미하게 큰 효과크기 차이(Cohen's d > .8)를 보여주었다. 이 연구 결과를 토대로 수정된 과학적 자기 효능감 척도를 활용하면 예비 교사들의 과학 과목에 대한 자기 효능감을 정확히 진단하는데 큰 기여를 할 것이라 판단된다. 또한 과학적 자기 효능감 검사 결과를 바탕으로 예비 교사들의 과학적 자기 효능감을 효과적으로 향상시킬 수 있는 교육과정 및 교육 내용 개편에도 기여할 수 있을 것이다.

남극 세종기지에서의 지표 플럭스 관측: II. 2002-2003년 남반구 여름 기간의 열과 수증기의 난류 교환 (Surface Flux Measurements at King Sejong Station in West Antarctica: II. Turbulent exchanges of sensible heat and latent heat in the austral summer of 2002-2003)

  • 최태진;이방용;이희춘;김성중;홍성민
    • 지구물리
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    • 제8권3호
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    • pp.159-167
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    • 2005
  • Turbulent fluxes of sensible heat and latent heat were analyzed at King Sejong station in the austral summer of 2002 (December) and 2003 (January and February). Monthly mean air temperatures of January and February (2.2oC) were similar to those averaged over 1988 to 2001. Precipitation was less in January and greater in February than those averaged over last 14 years. In December of 2002 and January, there was precipitation primarily when easterly wind blew usually. The frequency of snowfall was equal to or larger than that of rainfall. In the mean while, precipitation primarily in forms of rainfall occurred with westerly wind in February. In addition, while for easterly wind, temperature and humidity was low, temperature and humidity were high in case of westerly wind. Based on flux footprint, measured flux mainly came from within 300 m with maximum of 40 m upwind, indicating the insignificant role of the sea around the study site. Half-hourly downward short wave radiation amounted up to ∼ 1000 Wm-2 and net radiation ranged from -50 to 600 Wm-2. Half-hourly sensible heat flux was positive at daytime with maximum of ∼ 400 Wm-2, except the 27th and 28th in February of 2003 when it was negative all day despite of positive net radiation at short daytime. Latent heat flux was positive with maximum of ∼ 130 Wm-2. Depending on wind direction, the partitioning of net radiation into the sum of sensible heat flux and latent heat flux was larger than 0.8, indicating the strong source of the land surface for the atmospheric heating. The daytime averaged Bowen ratio (=sensible heat flux /latent heat flux) was significantly greater than 1, indicating that sensible heat flux was the main source to heat the atmosphere over the site.

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