• 제목/요약/키워드: Late effect

검색결과 1,514건 처리시간 0.049초

감마선을 조사 한 마우스에서 녹차 장기투여의 효과 (The Effect of Green Tea on Radion-induced Late Biological Effect in Mice)

  • 김세라;이해준;김휴경;이진희;오기석;박인철;오헌;조성기;김성호
    • 한국임상수의학회지
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    • 제20권2호
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    • pp.159-165
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    • 2003
  • This study was performed to determine the effect of green tea on the late biological effect (survival, hematological change, carcinogenesis) of mice irradiated with 3 Gy of gamma-radiation. There was little difference in body weights between normal and irradiated mice. Survival rate were decreased in irradiated mice and the survival rate and mean survival time of the groups treated with green tea were far better than the irradiation control group. An elevation of mean number of total leukocyte or lymphocyte counts was seen at week 12 of the group treated with green tea. Stimulated recovery by the extract from green tea was also observed in thrombocyte. Main gross findings of irradiated mice were appeared as enlargement of spleen, thymus and liver, tumorous nodules in lung and cyst or mass in ovary. Microscopically, there were various findings including hematopoietic and lymphoid tumor, lung cancer, ovarian cancer and cancer of other lesions. Green tea reduced the incidence of tumor development. Further studies are needed to characterize better the protective nature of active compounds.

GIS 자료와 일조모델을 이용한 자연적 및 인공적 지형에 의한 일조차단 평가 (Assessment of Blocking Effect of Natural and Artificial Topography on Sunshine Duration Using GIS Data and Sunshine Model)

  • 김도용;김재진
    • 대한공간정보학회지
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    • 제24권3호
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    • pp.67-73
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    • 2016
  • 본 연구에서는 하의도 남쪽 연안지역을 대상으로 자연적 및 인공적 지형에 의한 일조차단의 영향을 평가하였다. 지리정보시스템 자료를 이용하여 대상지역의 지형공간자료를 생산하고, 태양의 방위각과 고도각을 기반으로 3차원 일조환경평가 모델링을 수행하였다. 주간시간대에는 대상지역의 약 80~90% 이상의 영역에서 일조가 형성되었으며, 특히 하지(여름철)의 경우가 일조환경이 가장 우수한 것으로 평가되었다. 산악지형에 의한 일조차단의 영향은 일몰에 가까운 늦은 오후 시간대에 북쪽 주거지역에서 나타났다. 성토건설에 따라 형성되는 인공지형의 경우, 이른 오전 시간대에는 남쪽 주거지역의 일조환경에 영향을 미쳤으며, 늦은 오후 시간대에는 염전의 남서쪽 지역에 영향을 미치는 것으로 평가되었다.

Changes in growth performance, carcass characteristics, and meat properties of Hanwoo steers according to supplementation of composite feed additive

  • Ahn, Jun-Sang;Shin, Jong-Suh;Lee, Chang-Woo;Choi, Wook-Jin;Kim, Min-Ji;Choi, Jang-Gun;Son, Gi-Hwal;Chang, Sun-Six;Kwon, Eung-Gi;Park, Byung-Ki
    • 농업과학연구
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    • 제46권1호
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    • pp.11-25
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    • 2019
  • This study was conducted to evaluate the effects of a composite feed additive (CFA) consisting of vitamin C, vitamin E, selenium, and choline on growth performance, carcass characteristics, and meat properties of Hanwoo steers. Twenty-two late fattening steers were randomly assigned to one of two dietary groups, control (commercial concentrate + rice straw) and treatment (commercial concentrate + rice straw + 50 g of CFA). Average daily gain (ADG) was 4.0% higher in treatment than that in control; however, there was no statistically significant difference. The supplementation of CFA had no effect on overall yield or quality traits of carcass. CFA had no effect on chemical composition, water holding capacity, shear force, cooking loss, or myoglobin values in longissimus muscle; however, the content of ${\alpha}$-tocopherol was increased by supplementation of CFA (p < 0.01). The contents of ${\alpha}$-linolenic acid and n-3 fatty acids were higher in treatment group than in control (p < 0.01). The ratio of n-6/n-3 fatty acids was decreased by supplementation of CFA (p < 0.01). The supplementation of CFA had no effect on pH or thiobarbituric acid reactive substances (TBARS) values in longissimus muscle (raw); however, TBARS (cooked) values were lower in treatment group than in control during refrigerated storage (p < 0.01). Thus, the results indicate that the supplementation of CFA (vitamin C + vitamin E + selenium + choline) had some positive effects on the increase in ${\alpha}$-tocopherol and n-3 fatty in longissimus muscle, without any negative effect on growth performance or carcass characteristics of late fattening Hanwoo steers.

후기 황체기 불쾌기분 장애의 평가 방법 및 진단에 관한 예비 연구 - 정신과 외래환자를 대상으로 - (A Preliminary Study on Method for Evaluation and Diagnosis of Late Luteal Phase Dysphoric Disorder in Women - Focusing on Psychiatric Outpatients -)

  • 이상규;조숙행;곽동일
    • 정신신체의학
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    • 제3권2호
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    • pp.115-125
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    • 1995
  • Reports about the prevalence of premenstrual symptoms state that occurs in 20 to 100% of most reproductive-age women. There is a close association between premenstrual syndrome and affective disorders as well as same some other psychiatric disorders. Late luteal phase dysphoric disorder (LLPDD) is a premenstrual condition defined in DSM-III-R by severe mood changes and other symptoms that repeatedly occur only in the luteal phase of the menstrual cycle. However, DSM-III-R does not specify how to compute the change from the follicular to the luteal phase or how to determine when the amount of change is great enough to warrant the diagnosis nor how to determine occupational or social functional impairment. This study was conducted to evaluate the nature, severity and magnitude of premenstrual syndrome in women with current psychiatric disorders by using prospective Daily Rating Form(DRF), and to measure symptom changes according to three scoring methods for diagnosing LLPDD. Our study obtains the data about premenstrual changes estimated by DRF from 22 women with psychiatric disorders who had met criteria for major depressive syndrome on the Premenstrual Assessment Form (PAF). The data was scored by each three methods and was determined to meet criteria A for LLPDD. The results are as follows: 1) the subjects, when scored according to the percent change method, effect size method and absolute severity method, met the DSM-III-R criteria A for LLPDD in 36.4% (8 subjects), 14% (3 subjects) and 4.5% (1 subject) of the cases respectively. 2) The items of irritability, anger and impatience were occurred most frequently on the DRF, when it was scored according to the three scoring methods. And the item of breast pain was next frequent according to the effect size method and the percent change method but according to the absolute severity method. 3) The PAF item of impaired social functioning was reported by 16 (73%) of the subjects. 4) 4 (18%) of the subjects met criteria A for LLPDD and reported impaired social functioning. The prevalency of LLPDD according to each method varied. The percent change method yielded the greatest (36.4%), and the absolute seventy method yielded the laest (4.5%), The effect size method yielded an intermediate frequency (14%). Therefore, for maximizing the diagnostic accuracy of LLPDD, a diagnostic procedure including a measure of change (e.q., effect size method, percent change method) as well as confirmed diagnosis by DRF, will be needed. Also, an accurate tool to evaluate impaired social functioning will be required.

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HMD기반 몰입형 VR 학습에서 방해요인, 프레즌스, 몰입, 학습효과 사이의 관계에 관한 연구 (A Study on the Relationship of Distraction Factors, Presence, Flow, and Learning Effects in HMD-based Immersed VR Learning)

  • 권종산
    • 한국멀티미디어학회논문지
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    • 제21권8호
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    • pp.1002-1020
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    • 2018
  • Virtual reality (VR) technologies, which have been improved of late, offer experiences closer to reality than before. While VR technologies are expected to be an effective medium if used in learning content that cannot be offered in real life, distraction factors in VR technologies may prevent the users' presence and flow, making these technologies ineffective. Therefore, this study, through experiment and observation, analyzed the effect of distraction factors on the user's experience perception and learning effect when using HMD-based immersive VR. Experimental results revealed that the distraction factors were shown to have a negative, albeit not generally significant (except for tactile interactivity), effect on vividness, tactile interactivity, locomotive interactivity, presence, and flow. Ultimately, they were shown to have a negative effect on learning.

기아를 일으킨 흰쥐의 생명연장에 미치는 천연약물의 효과 (Effect of Natural Drugs on the Life Support of Starving Rats)

  • 박시원;이현아
    • 약학회지
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    • 제39권1호
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    • pp.14-23
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    • 1995
  • The current study was undertaken to select the crude drug showing life prolonging effect on the starved rats(Sprague-Dawley) and elucidate the reaction mechanism there of. As distilled water extracts prepared from twenty kinds of natural drugs were administered orally to female starved rats, Bupleuri Radix demonstrated the most prominent effect with 34.6% increment in the survival time. To investigate underlying mechanism of life prolonging effect of Bupleuri Radix, the concentrations of adrenocorticosteroids(corticsterone, testosterone and aldosterone) and enzyme activities of superoxide dismutase(SOD), glutamate oxaloacetate transaminase(GOT), glutamate pyrurate transaminase(GPT) were assayed in the serums of rats starved for, 2, 4 and 6 days respectively. The results manifested much elevated values of corticosterone, aldosterone(2 days) and rather decreasing tendency afterwards, specially in the late periods of starvation(6 days). With respect to such a considerable changes according to starvation periods, Bupleur Radix restored these values much near to normal suggesting that Buplerum Radix may play a life prolonging action during starvation probably through reinforcing the homeostatic properties of corticosteroids and some enzyme activities.

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Applicability of Coda Wave Interferometry Technique for Measurement of Acoustoelastic Effect of Concrete

  • Shin, Sung Woo
    • 비파괴검사학회지
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    • 제34권6호
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    • pp.428-434
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    • 2014
  • In this study, we examined the applicability of coda wave interferometry (CWI) technique, which was developed to characterize seismic waves, to detect and evaluate change in the velocity of ultrasonic waves in concrete due to acoustoelastic effect. Ultrasonic wave measurements and compressive loading tests were conducted on a concrete specimen. The measured wave signals were processed with CWI to detect and evaluate the relative velocity change with respect to the stress state of the specimen. A phase change due to the acoustoelastic effect of concrete was clearly detected in the late-arriving coda wave. This shows that the relative velocity change of ultrasonic waves in concrete due to the acoustoelastic effect can be evaluated successfully and precisely using CWI.

토마토에서 아메리카잎굴파리의 발생, 가해양상 및 살충제처리 효과 (Occurrence, Injury aspects and Effect of insecticide applications of Liriomyza trifolii Burgess on Tomato Cultivated in Plastic house)

  • 박종대;엄기백;유재기;김상철
    • 농약과학회지
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    • 제4권2호
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    • pp.50-55
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    • 2000
  • 토마토를 가해하는 아메리카잎굴파리의 발생과 가해양상 그리고 살충제처리에 의한 아메리카잎굴파리의 방제가 토마토 생육에 미치는 영향을 구명하기 위하여 1997년부터 1998년까지 전남지방의 플라스틱하우스를 중심으로 연구하였다. 봄 재배에서 황색끈끈이트랩과 sweeping에 의한 조사 결과는 5월 하순부터 밀도가 급격히 증가하였으며 sweeping 보다는 끈끈이트랩 조사에 의한 밀도변동이 뚜렷하였다. 피해엽율은 5년 이상 계속하여 토마토를 재배한 포장에서는 년중 피해엽을 확인할 수 있었으며, 4월 상순 이전에는 20%이하, 중순 30%, 하순 40%, 5월 상순에 60%, 하순이후에는 80%수준이었다. 반면 처녀재배지에서는 정식후 6주째부터 피해엽이 나타나기 시작하였으며 피해엽율은 80%수준으로 급격히 높아졌다. 가을재배에서는 재배연수에 관계없이 정식때부터 피해엽율이 80%수준을 유지하였다. 성충과 유충의 발생소장은 봄재배의 경우 5월하순부터 성충이 유인되었고 6월하순에 포회량이 가장 많았으나 종령유충은 발생초기부터 주당 $6{\sim}8$마리로 수확기까지 거의 비슷한 밀도 수준을 유지하였다. 가을재배의 경우 정식직후부터 3주째까지는 성충과 유충의 밀도가 높게 유지되었으나 4주째인 9월상순부터는 밀도가 급격히 떨어졌다. 살충제처리에 의한 방제 효과는 클로르페나피르 유제, 싸이로마진 수화제, 아바멕틴 유제가 아메리카잎굴파리의 유충의 밀도를 효과적으로 억제시킬 수 있었다.

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TMF와 배합사료의 급여방법이 거세한우의 성장 및 도체특성에 미치는 영향 (Comparison of Growth Performance, Carcass and Meat Characteristics According to the Feeding Method of Concentrate and Total Mixed Fermentation in Hanwoo Steers)

  • 박병기;안준상;최장근;권응기;신종서
    • 한국초지조사료학회지
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    • 제39권4호
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    • pp.281-291
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    • 2019
  • 본 연구는 TMF 및 배합사료 급여방법의 차이가 거세한우의 사양성적 및 도체 특성에 미치는 영향을 검토하기 위하여 수행되었다. 공시동물은 거세한우 24두(166.3±34.4kg)를 이용하였으며, 시험구배치는 육성기부터 비육후기까지 배합사료와 볏짚을 급여하는 대조구, 육성기부터 비육전기까지 TMF를 급여하고 비육후기에는 배합 사료와 볏짚을 급여하는 T1 및 육성기부터 비육후기까지 TMF를 급여하는 T2의 3처리로 하였다. 일당증체량 및 건물섭취량은 처리구간 차이는 없었으며, 혈중 cholesterol 및 HDL-cholesterol 농도는 대조구에 T2에서 증가되는 결과를 보였다(p<0.05). TMF 및 배합사료의 급여방법이 거세한우의 육량등급 및 육질등급에 미치는 영양은 없었으며, 등심의 명도는 대조구 및 T2구에 비해 T1구에서 증가되는 결과를 보였다(p<0.05). PUFA 비율은 대조구에 비해 T2에서 증가되는 것으로 나타났다. 따라서, TMF 및 배합사료의 급여 방법은 거세한우의 성장과 도체등급에 미치는 영향 없이 등심의 육색 및 지방산 조성에 긍정적인 영향을 미칠 수 있을 것으로 판단되며, 향후 공시두수 및 사료 배합비 등에 따른 추가 연구가 필요할 것으로 생각된다.

The effect of nutrition and body condition of triplet-bearing ewes during late pregnancy on the behaviour of ewes and lambs

  • Gronqvist, Gabriella V.;Corner-Thomas, Rene A.;Kenyon, Paul R.;Stafford, Kevin J.;Morris, Stephen T.;Hickson, Rebecca E.
    • Asian-Australasian Journal of Animal Sciences
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    • 제31권12호
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    • pp.1991-2000
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    • 2018
  • Objective: Triplet-born lambs are less likely to survive to weaning than twin-born or single-born lambs. Appropriate ewe-lamb bonding behaviours and lamb vigour behaviours are necessary for survival of lambs. The aim of this experiment was to determine whether maternal nutrition during late pregnancy influenced behaviour of the ewe and her lambs soon after birth, and to determine whether mid-pregnancy body condition score (BCS) influenced any behavioural response. Methods: The experiments included ewes that were in BCS 2.0, 2.5, or 3.0 in mid-pregnancy and were fed either ad libitum or to pregnancy-maintenance requirements in late-pregnancy (day 115 until 136 in experiment one, and day 128 until 141 in experiment two). The time taken for lambs to stand, contact dam, suck from dam and follow dam was recorded three to 18 h after birth. The number of high- and low-pitched bleats emitted by the ewe and lambs was recorded, along with maternal behaviour score (MBS) of the ewe. Lambs in experiment two underwent a maternal-recognition test at 12 or 24 h. Results: There were significant effects of feeding treatment on bleating behaviour of ewes and lambs, but these were inconsistent among BCS groups and between experiments. Lamb vigour behaviours were not affected by feeding treatment. In experiment one, there was no effect of feeding treatment or BCS on MBS, but in experiment two, ewes in BCS3 in mid-pregnancy had greater MBS than ewes in BCS2 in mid-pregnancy (MBS 3.1/5 vs MBS 2.1/5; p<0.05). Conclusion: Given there were no repeatable effects on behaviour of ewes and lambs, ad libitum feeding rather than feeding for pregnancy-maintenance requirements cannot be used to improve behaviours soon after birth of triplet-bearing ewes in BCS 2-3 and their lambs in extensive pastoral conditions.